REFERENCES
- Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1994. Current protocols in molecular biology, p. 113–141. John Wiley & Sons, Inc., New York, N.Y.
- Baker, J. C., and R. M. Harland. 1996. A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes Dev. 10:1880–1889.
- Chen, R. H., P. J. Miettinen, E. M. Maruoka, L. Choy, and R. Derynck. 1995. A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor. Nature 377:548–552.
- Derynck, R. 1994. TGF-β receptor-mediated signaling. Trends Biochem. Sci. 19:548–553.
- Derynck, R. 1994. Transforming growth factor-beta, p. 319–342. In A. W. Thomson (ed.), The cytokine handbook. Academic Press, Inc., San Diego, Calif.
- Derynck, R., and Y. Zhang. 1996. The Mad way to do it. Curr. Biol. 6:1226–1229.
- Ebner, R., R.-H. Chen, L. Shum, S. Lawler, T. F. Zioncheck, A. Lee, A. R. Lopez, and R. Derynck. 1993. Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor. Science 260:1344–1348.
- Feng, X. H., E. H. Filvaroff, and R. Derynck. 1995. Transforming growth factor-beta (TGF-beta)-induced down-regulation of cyclin A expression requires a functional TGF-beta receptor complex. Characterization of chimeric and truncated type I and type II receptors. J. Biol. Chem. 270:24237–24245.
- Graff, J. M., A. Bansal, and D. A. Melton. 1996. Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily. Cell 85:479–487.
- Gyuris, J., E. Golemis, H. Chertkov, and R. Brent. 1993. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75:791–803.
- Hahn, S. A., M. Schutte, A. T. Hoque, C. A. Moskaluk, L. T. da Costa, E. Rozenblum, C. L. Weinstein, A. Fischer, C. J. Yeo, R. H. Hruban, and S. E. Kern. 1996. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350–353.
- Hogan, B. 1996. Bone morphogenetic protein: multifunctional regulators of vertebrate development. Genes Dev. 10:1580–1594.
- Hoodless, P. A., T. Haerry, S. Abdollah, M. Stapleton, M. B. O’Connor, L. Attisano, and J. L. Wrana. 1996. MADR1, a MAD-related protein that functions in BMP2 signalling pathways. Cell 85:489–500.
- Kawabata, M., T. Imamura, K. Miyazono, M. E. Engel, and H. L. Moses. 1995. Interaction of the transforming growth factor-beta type I receptor with farnesyl-protein transferase-alpha. J. Biol. Chem. 270:29628–29631.
- Keeton, M. R., S. A. Curriden, A. van Zonneveld, and D. J. Loskutoff. 1991. Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta. J. Biol. Chem. 266:23048–23052.
- Kingsley, D. M. 1994. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8:133–146.
- Lagna, G., A. Hata, A. Hemmati-Brivanlou, and J. Massague. 1996. Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 383:832–836.
- Liu, F., A. Hata, J. C. Baker, J. Doody, J. Carcamo, R. M. Harland, and J. Massague. 1996. A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381:620–623.
- Massague, J. 1996. TGFβ signaling: receptors, transducers, and Mad proteins. Cell 85:947–950.
- Sekelsky, J. J., S. J. Newfeld, L. A. Raftery, E. H. Chartoff, and W. M. Gelbart. 1995. Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139:1347–1358.
- Ventura, F., F. Liu, J. Doody, and J. Massague. 1996. Interaction of transforming growth factor-β receptor I with farnesyl-protein transferase-a in yeast and mammalian cells. J. Biol. Chem. 271:13931–13934.
- Wang, T., P. K. Donahoe, and A. S. Zervos. 1994. Specific interaction of type I receptors of the TGF-β family with the immunophilin FKBP-12. Science 265:674–676.
- Wrana, J. L., L. Attisano, R. Wieser, F. Ventura, and J. Massague. 1994. Mechanism of activation of the TGF-β receptor. Nature 370:341–347.
- Zervos, A. S., J. Gyuris, and R. Brent. 1993. Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell 72:223–232.
- Zhang, Y., X.-H. Feng, R.-Y. Wu, and R. Derynck. 1996. Receptor-associated Mad homologues synergize as effectors of the TGF-beta response. Nature 383:168–172.
- Zhang, Y., T. Musci, and R. Derynck. The tumor suppressor Smad4/DPC4 as a central mediator of Smad function. Curr. Biol., in press.