Regulation of IκBβ in WEHI 231 Mature B Cells

REFERENCES

• Atchison, M., and R. Perry. 1987. The role of the к enhancer and its binding factor NF-kB in the developmental regulation of к gene transcription. Cell 48:121–128.
   PubMed Web of Science ®Google Scholar
• Baldwin, A. S. 1996. The NF-kB and IkB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:649–681.
   PubMed Web of Science ®Google Scholar
• Beg, A. A., and A. S. Baldwin, Jr. 1993. The IkB proteins: multifunctional regulators of Rel/NF-кВ transcription factors. Genes Dev. 7:2064–2070.
   PubMed Web of Science ®Google Scholar
• Bours, V., P. R. Burd, K. Brown, J. Villalobos, S. Park, R. P. Ryseck, R. Bravo, K. Kelly, and U. Siebenlist. 1992. A novel mitogen-inducible gene product related to p50/p105-NF-KB participates in transactivation through a kB site. Mol. Cell. Biol. 12:685–695.
   PubMed Web of Science ®Google Scholar
• Chen, Z. J., L. Parent, and T. Maniatis. 1996. Site-specific phosphorylation of iKB-α by a novel ubiquitination-dependent protein kinase activity. Cell 84:853–862.
   PubMed Web of Science ®Google Scholar
• Chiao, P. J., S. Miyamoto, and I. M. Verma. 1994. Autoregulation of IkB-α activity. Proc. Natl. Acad. Sci. USA 91:28–32.
   PubMed Web of Science ®Google Scholar
• Chu, Z.-L., T. A. McKinsey, L. Liu, X. Qi, and D. W. Ballard. 1996. Basal phosphorylation of the PEST domain in IkBβ regulates its functional interaction with the c-rel proto-oncogene product. Mol. Cell. Biol. 16:5974–5984.
   PubMedGoogle Scholar
• Davis, N., S. Ghosh, D. L. Simmons, P. Tempst, H. C. Liou, D. Baltimore, and H. R. Bose, Jr. 1991. Rel-associated pp40: an inhibitor of the rel family of transcription factors. Science 253:1268–1271.
   PubMedGoogle Scholar
• de Martin, R., B. Vanhove, Q. Cheng, E. Hofer, V. Csizmadia, H. Winkler, and F. Bach. 1993. Cytokine-inducible expression in endothelial cells of an IKB-α-like gene is regulated by NF-kB. EMBO J. 12:2773–2779.
   PubMed Web of Science ®Google Scholar
• DiDonato, J., F. Mercurio, C. Rosette, J. Wu-Li, H. Suyang, S. Ghosh, and M. Karin. 1996. Mapping of the inducible IkB phosphorylation sites that signal its ubiquitination and degradation. Mol. Cell. Biol. 16:1295–1304.
   PubMed Web of Science ®Google Scholar
• Frankenberger, M., A. Pforte, T. Sternsdorf, B. Passlick, P. A. Baeuerle, and H. W. Ziegler-Heitbrock. 1994. Constitutive nuclear NF-kB in cells of the monocyte lineage. Biochem. J. 304:87–94.
   PubMedGoogle Scholar
• Ghosh, S., and D. Baltimore. 1990. Activation in vitro of NF-kB by phosphorylation of its inhibitor IkB. Nature 344:678–682.
   PubMed Web of Science ®Google Scholar
• Ghosh, S., A. M. Gifford, L. R. Rivere, P. Tempest, G. P. Nolan, and D. Baltimore. 1990. Cloning of the p50 DNA binding subunit of NF-kB: homology to rel and dorsal. Cell 62:1019–1029.
   PubMed Web of Science ®Google Scholar
• Grumont, R. J., I. B. Richardson, C. Gaff, and S. Gerondakis. 1993. rel/NF-KB nuclear complexes that bind kB sites in the murine c-rel promoter are required for constitutive c-rel transcription in B-cells. Cell Growth Diff. 4:731–43.
   PubMedGoogle Scholar
• Haskill, S., A. A. Beg, S. M. Tompkins, J. S. Morris, A. D. Yurochko, A. Sampson-Johannes, K. Mondal, P. Ralph, and A. S. Baldwin, Jr. 1991. Characterization of an immediate-early gene induced in adherent monocytes that encodes iKB-like activity. Cell 65:1281–1289.
   PubMed Web of Science ®Google Scholar
• Henkel, T., T. Machleidt, I. Alkalay, M. Kronke, Y. Ben-Neriah, and P. Baeuerle. 1993. Rapid proteolysis of iKB-α is necessary for activation of transcription factor NF-kB. Nature 365:182–185.
   PubMed Web of Science ®Google Scholar
• Kieran, M., V. Blank, F. Logeat, J. Vandekerckhove, F. Lottspeich, O. Le Bail, M. B. Urban, P. Kourilsky, P. A. Baeuerle, and A. Israel. 1990. The DNA binding subunit of NF-kB is identical to factor KBF 1 and homologous to the rel oncogene product. Cell 62:1007–1018.
   PubMed Web of Science ®Google Scholar
• Kopp, E., and S. Ghosh. 1995. NF-kB and rel proteins in innate immunity. Adv. Immunol. 58:1–27.
   PubMed Web of Science ®Google Scholar
• Le Bail, O., R. Schmidt-Ullrich, and A. Israel. 1993. Promoter analysis ofthe gene encoding the IkB-o/MAD3 inhibitor of NF-kB: positive regulation by members of the rel/NF-KB family. EMBO J. 12:5043–5049.
   PubMed Web of Science ®Google Scholar
• Lenardo, M., J. W. Pierce, and D. Baltimore. 1987. Protein-binding sites in ig gene enhancers determine transcriptional activity and inducibility. Science 236:1573–1577.
   PubMed Web of Science ®Google Scholar
• Liou, H. C., W. C. Sha, M. L. Scott, and D. Baltimore. 1994. Sequential induction of NF-KB/Rel family proteins during B-cell terminal differentiation. Mol. Cell. Biol. 14:5349–5359.
   PubMed Web of Science ®Google Scholar
• McKinsey, T. A., J. A. Brockman, D. C. Scherer, S. W. Al-Murrani, P. L. Green, and D. W. Ballard. 1996. inactivation of iKBβ by the Tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kB. Mol. Cell. Biol. 16:2083–2090.
   Google Scholar
• Miyamoto, S., P. Chiao, and I. M. Verma. 1994. Enhanced iKBα degradation is responsible for constitutive NF-kB activity in mature murine B-cell lines. Mol. Cell. Biol. 14:3276–3282.
   PubMedGoogle Scholar
• Miyamoto, S., M. J. Schmidt, and I. M. Verma. 1994. Qualitative changes in the subunit composition of KB-binding complexes during murine B cell differentiation. Proc. Natl. Acad. Sci. USA 91:5056–5060.
   PubMedGoogle Scholar
• Molitor, J. A., D. W. Ballard, and W. C. Greene. 1991. Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation. New Biol. 3:987–996.
   PubMedGoogle Scholar
• Neri, A., C. C. Chang, L. Lombardi, M. Salina, P. Corradini, A. T. Maiolo, R. S. Chaganti, and R. Dalla-Favera. 1991. B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kB p50. Cell 67:1075–1087.
   PubMed Web of Science ®Google Scholar
• Nolan, G., S. Ghosh, H.-C. Liou, P. Tempst, and D. Baltimore. 1991. DNA binding and IkB inhibition of the cloned p65 subunit of NF-kB, a rel-related polypeptide. Cell 64:961–969.
   PubMed Web of Science ®Google Scholar
• Phillips, R. J., and S. Ghosh. Unpublished data.
   Google Scholar
• Phillips, R. J., S. Gustafson, and S. Ghosh. 1996. identification of a novel NF-kB p50-related protein in B lymphocytes. Mol. Cell. Biol. 16:7089–7097.
   PubMedGoogle Scholar
• Rice, N. R., and M. K. Ernst. 1993. in vivo control of NF-kB activation by iKB-α. EMBO J. 12:4685–4695.
   PubMedGoogle Scholar
• Ruben, S., P. Dillon, R. Schreck, T. Henkel, C. Chen, M. Maher, P. Baeuerle, and C. Rosen. 1991. isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kB. Science 251:1490–1493.
   PubMedGoogle Scholar
• Ryseck, R.-P., P. Bull, M. Takamiya, V. Bours, U. Siebenlist, P. Dobrzanski, and R. Bravo. 1992. RelB, a new Rel family transcription activator that can interact with p50-NF-KB. Mol. Cell. Biol. 12:674–684.
   PubMedGoogle Scholar
• Schmid, R. M., N. D. Perkins, C. S. Duckett, P. C. Andrews, and G. J. Nabel. 1991. Cloning of an NF-kB subunit which stimulates HIV transcription in synergy with p65. Nature 352:733–736.
   PubMed Web of Science ®Google Scholar
• Schreck, R., B. Meier, D. N. Mannel, W. Droge, and P. A. Baeuerle. 1992. Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells. J. Exp. Med. 175:1181–1194.
   PubMed Web of Science ®Google Scholar
• Sen, R., and D. Baltimore. 1986. inducibility of к immunoglobulin enhancer-binding protein NF-kB by a posttranslational mechanism. Cell 47:921–928.
   PubMed Web of Science ®Google Scholar
• Sen, R., and D. Baltimore. 1986. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46:705–716.
   PubMed Web of Science ®Google Scholar
• Suyang, H., R. Phillips, I. Douglas, and S. Ghosh. 1996. Role of unphos-phorylated, newly synthesized IKBβ in persistent activation of NF-kB. Mol. Cell. Biol. 16:5444–5449.
   Google Scholar
• Ten, R. M., C. V. Paya, N. Israel, O. Le Bail, M. G. Mattei, J. L. Virelizier, P. Kourilsky, and A. Israel. 1992. The characterization of the promoter of the gene encoding the p50 subunit of NF-kB indicates that it participates in its own regulation. EMBO J. 11:195–203.
   PubMed Web of Science ®Google Scholar
• Thompson, J., R. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghosh. 1995. IKB-β regulates the persistent response in a biphasic activation of NF-kB. Cell 80:573–582.
   PubMed Web of Science ®Google Scholar
• Verma, I. M., J. K. Stevenson, E. M. Schwarz, D. Van Antwerp, and S. Miyamoto. 1995. Rel/NF-KB/lKB family: intimate tales of association and dissociation. Genes Dev. 9:2723–2735.
   PubMed Web of Science ®Google Scholar