22
Views
51
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Regulation of Myogenesis by Fibroblast Growth Factors Requires Beta-Gamma Subunits of Pertussis Toxin-Sensitive G Proteins

, &
Pages 5780-5787 | Received 09 Apr 1998, Accepted 04 Jul 1998, Published online: 28 Mar 2023

REFERENCES

  • Bennett, A. M., and N. K. Tonks 1997. Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases. Science 278: 1288–1291.
  • Bladt, F., D. Riethmacher, S. Isenmann, A. Aguzzi, and C. Birchmeier 1995. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature 376: 768–771.
  • Blank, J. L., P. Gerwins, E. M. Elliott, S. Sather, and G. L. Johnson 1996. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase. J. Biol. Chem. 271: 5361–5368.
  • Bogoyevitch, M. A., P. E. Glennon, M. B. Andersson, A. Clerk, A. Lazou, C. J. Marshall, P. J. Parker, and P. H. Sugden 1994. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. J. Biol. Chem. 269: 1110–1119.
  • Brand-Saberi, B., T. S. Muller, J. Wilting, B. Christ, and C. Birchmeier 1996. Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo. Dev. Biol. 179: 303–308.
  • Bruder, J. T., G. Heidecker, and U. R. Rapp 1992. Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase. Genes Dev. 6: 545–556.
  • Cai, H., U. Smola, V. Wixler, I. Eisenmann-Tappe, M. T. Diaz-Meco, J. Moscat, U. Rapp, and G. M. Cooper 1997. Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase. Mol. Cell. Biol. 17: 732–741.
  • Campbell, J. S., M. P. Wenderoth, S. D. Hauschka, and E. G. Krebs 1995. Differential activation of mitogen-activated protein kinase in response to basic fibroblast growth factor in skeletal muscle cells. Proc. Natl. Acad. Sci. USA 92: 870–874.
  • Camps, M., A. Carozzi, P. Schnabel, A. Scheer, P. J. Parker, and P. Gierschik 1992. Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits. Nature 360: 684–686.
  • Clegg, C. H., T. A. Linkhart, B. B. Olwin, and S. D. Hauschka 1987. Growth factor control of skeletal muscle differentiation: commitment to terminal differentiation occurs in G1 phase and is repressed by fibroblast growth factor. J. Cell Biol. 105: 949–956.
  • Crespo, P., T. G. Cachero, N. Xu, and J. S. Gutkind 1995. Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition. J. Biol. Chem. 270: 25259–25265.
  • Crespo, P., N. Xu, W. F. Simonds, and J. S. Gutkind 1994. Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits. Nature 369: 418–420.
  • Della Rocca, G. J., T. van Biesen, Y. Daaka, D. K. Luttrell, L. M. Luttrell, and R. J. Lefkowitz 1997. Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. J. Biol. Chem. 272: 19125–19132.
  • Exton, J. H. 1997. Cell signalling through guanine-nucleotide-binding regulatory proteins (G proteins) and phospholipases. Eur. J. Biochem. 243: 10–20.
  • Faure, M., T. A. Voyno-Yasenetskaya, and H. R. Bourne 1994. cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J. Biol. Chem. 269: 7851–7854.
  • Floss, T., H. H. Arnold, and T. Braun 1997. A role for FGF-6 in skeletal muscle regeneration. Genes Dev. 11: 2040–2051.
  • Fong, H. K., J. B. Hurley, R. S. Hopkins, R. Miake-Lye, M. S. Johnson, R. F. Doolittle, and M. I. Simon 1986. Repetitive segmental structure of the transducin beta subunit: homology with the CDC4 gene and identification of related mRNAs. Proc. Natl. Acad. Sci. USA 83: 2162–2166.
  • Gardner, A. M., R. R. Vaillancourt, and G. L. Johnson 1993. Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins. J. Biol. Chem. 268: 17896–17901.
  • Gautam, N., M. Baetscher, R. Aebersold, and M. I. Simon 1989. A G protein gamma subunit shares homology with ras proteins. Science 244: 971–974.
  • Gines, P., X. Li, S. E. Brown, T. Nakamura, P. S. Guzelian, L. E. Heasley, R. W. Schrier, and R. A. Nemenoff 1996. Inhibitory actions of cyclic adenosine monophosphate and pertussis toxin define two distinct epidermal growth factor-regulated pathways leading to activation of mitogen-activated protein kinase in rat hepatocytes. Hepatology 23: 1167–1173.
  • Gray, L. S., K. S. Huber, M. C. Gray, E. L. Hewlett, and V. H. Engelhard 1989. Pertussis toxin effects on T lymphocytes are mediated through CD3 and not by pertussis toxin catalyzed modification of a G protein. J. Immunol. 142: 1631–1638.
  • Hannon, K., A. J. Kudla, M. J. McAvoy, K. L. Clase, and B. B. Olwin 1996. Differentially expressed fibroblast growth factors regulate skeletal muscle development through autocrine and paracrine mechanisms. J. Cell Biol. 132: 1151–1159.
  • Hannon, K., M. M. McAvoy, and B. B. Olwin. 1998. Unpublished observation.
  • Itoh, N., T. Mima, and T. Mikawa 1996. Loss of fibroblast growth factor receptors is necessary for terminal differentiation of embryonic limb muscle. Development 122: 291–300.
  • Iyengar, R. 1993. Molecular and functional diversity of mammalian Gs-stimulated adenylyl cyclases. FASEB J. 7: 768–775.
  • Janknecht, R., and T. Hunter 1997. Convergence of MAP kinase pathways on the ternary complex factor Sap-1a. EMBO J. 16: 1620–1627.
  • Johnson, G. L., and R. R. Vaillancourt 1994. Sequential protein kinase reactions controlling cell growth and differentiation. Curr. Opin. Cell Biol. 6: 230–238.
  • Jones, N. C., Y. V. Fedorov, and B. B. Olwin. Submitted for publication.
  • Kaslow, H. R., and D. L. Burns 1992. Pertussis toxin and target eukaryotic cells: binding, entry, and activation. FASEB J. 6: 2684–2690.
  • Kelvin, D. J., G. Simard, H. H. Tai, T. P. Yamaguchi, and J. A. Connolly 1989. Growth factors, signaling pathways, and the regulation of proliferation and differentiation in BC3H1 muscle cells. I. A pertussis toxin-sensitive pathway is involved. J. Cell Biol. 108: 159–167.
  • Kinane, T. B., I. Kang, A. Chu, S. H. Chin, and L. Ercolani 1997. G alpha(i-2) mediates renal LLC-PK1 growth by a Raf-independent activation of p42/p44 MAP kinase. Am. J. Physiol. 272: F273–F282.
  • Koch, W. J., B. E. Hawes, L. F. Allen, and R. J. Lefkowitz 1994. Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras. Proc. Natl. Acad. Sci. USA 91: 12706–12710.
  • Koch, W. J., B. E. Hawes, J. Inglese, L. M. Luttrell, and R. J. Lefkowitz 1994. Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. J. Biol. Chem. 269: 6193–6197.
  • Kouhara, H., Y. R. Hadari, T. Spivak-Kroizman, J. Schilling, D. Bar-Sagi, I. Lax, and J. Schlessinger 1997. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89: 693–702.
  • Krapivinsky, G., L. Krapivinsky, K. Wickman, and D. E. Clapham 1995. G beta gamma binds directly to the G protein-gated K+ channel, IKACh. J. Biol. Chem. 270: 29059–29062.
  • Kudla, A. J., M. L. John, D. F. Bowen-Pope, B. Rainish, and B. B. Olwin 1995. A requirement for fibroblast growth factor in regulation of skeletal muscle growth and differentiation cannot be replaced by activation of platelet-derived growth factor signaling pathways. Mol. Cell. Biol. 15: 3238–3246.
  • Kudla, A. J., N. C. Jones, R. S. Rosenthal, K. Arthur, K. L. Clase, and B. B. Olwin 1998. The FGF receptor-1 tyrosine kinase domain regulates myogenesis but is not sufficient to stimulate proliferation. J. Cell Biol. 142: 241–250.
  • Lim, R. W., and S. D. Hauschka 1984. EGF responsiveness and receptor regulation in normal and differentiation-defective mouse myoblasts. Dev. Biol. 105: 48–58.
  • Linkhart, T. A., C. H. Clegg, and S. D. Hauschka 1980. Control of mouse myoblast commitment to terminal differentiation by mitogens. J. Supramol. Struct. 14: 483–498.
  • Logan, A., and S. D. Logan 1991. Studies on the mechanisms of signalling and inhibition by pertussis toxin of fibroblast growth factor-stimulated mitogenesis in Balb/c 3T3 cells. Cell. Signalling 3: 215–223.
  • Luttrell, L. M., T. van Biesen, B. E. Hawes, W. J. Koch, K. Touhara, and R. J. Lefkowitz 1995. G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor. J. Biol. Chem. 270: 16495–16498.
  • Macrez, N., J. L. Morel, F. Kalkbrenner, P. Viard, G. Schultz, and J. Mironneau 1997. A betagamma dimer derived from G13 transduces the angiotensin AT1 receptor signal to stimulation of Ca2+ channels in rat portal vein myocytes. J. Biol. Chem. 272: 23180–23185.
  • Mansour, S. J., W. T. Matten, A. S. Hermann, J. M. Candia, S. Rong, K. Fukasawa, G. F. Vande Woude, and N. G. Ahn 1994. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265: 966–970.
  • Marquardt, B., D. Frith, and S. Stabel 1994. Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: reconstitution of the signalling pathway in vitro. Oncogene 9: 3213–3218.
  • Milasincic, D. J., M. R. Calera, S. R. Farmer, and P. F. Pilch 1996. Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways. Mol. Cell. Biol. 16: 5964–5973.
  • Mitev, V., R. Le Panse, B. Coulomb, L. Miteva, and L. M. Houdebine 1995. Epidermal growth factor stimulates mitogen-activated protein kinase by a PKC-dependent pathway in human keratinocytes. Biochem. Biophys. Res. Commun. 208: 245–252.
  • Mourey, R. J., Q. C. Vega, J. S. Campbell, M. P. Wenderoth, S. D. Hauschka, E. G. Krebs, and J. E. Dixon 1996. A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation. J. Biol. Chem. 271: 3795–3802.
  • Munsterberg, A. E., J. Kitajewski, D. A. Bumcrot, A. P. McMahon, and A. B. Lassar 1995. Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev. 9: 2911–2922.
  • Olwin, B. B., and A. Rapraeger 1992. Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate. J. Cell Biol. 118: 631–639.
  • Poiraudeau, S., M. Lieberherr, N. Kergosie, and M. T. Corvol 1997. Different mechanisms are involved in intracellular calcium increase by insulin-like growth factors 1 and 2 in articular chondrocytes: voltage-gated calcium channels, and/or phospholipase C coupled to a pertussis-sensitive G-protein. J. Cell Biochem. 64: 414–422.
  • Quaife, C. J., C. A. Pinkert, D. M. Ornitz, R. D. Palmiter, and R. L. Brinster 1987. Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice. Cell 48: 1023–1034.
  • Rando, T. A., and H. M. Blau 1994. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J. Cell Biol. 125: 1275–1287.
  • Rapraeger, A. C., S. Guimond, A. Krufka, and B. B. Olwin 1994. Regulation by heparan sulfate in fibroblast growth factor signaling. Methods Enzymol. 245: 219–240.
  • Rapraeger, A. C., A. Krufka, and B. B. Olwin 1991. Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science 252: 1705–1708.
  • Reimann, T., U. Hempel, S. Krautwald, A. Axmann, R. Scheibe, D. Seidel, and K. W. Wenzel 1997. Transforming growth factor-beta1 induces activation of Ras, Raf-1, MEK and MAPK in rat hepatic stellate cells. FEBS Lett. 403: 57–60.
  • Rodan, S. B., G. Wesolowski, K. A. Thomas, K. Yoon, and G. A. Rodan 1989. Effects of acidic and basic fibroblast growth factors on osteoblastic cells. Connect. Tissue Res. 20: 283–288.
  • Rosoff, P. M., R. Walker, and L. Winberry 1987. Pertussis toxin triggers rapid second messenger production in human T lymphocytes. J. Immunol. 139: 2419–2423.
  • Sa, G., and P. L. Fox 1994. Basic fibroblast growth factor-stimulated endothelial cell movement is mediated by a pertussis toxin-sensitive pathway regulating phospholipase A2 activity. J. Biol. Chem. 269: 3219–3225.
  • Seed, J., and S. D. Hauschka 1988. Clonal analysis of vertebrate myogenesis. VIII. Fibroblasts growth factor (FGF)-dependent and FGF-independent muscle colony types during chick wing development. Dev. Biol. 128: 40–49.
  • Seger, R., and E. G. Krebs 1995. The MAPK signaling cascade. FASEB J. 9: 726–735.
  • Tamura, M., K. Nogimori, M. Yajima, K. Ase, and M. Ui 1983. A role of the B-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells. J. Biol. Chem. 258: 6756–6761.
  • Tang, W. J., and A. G. Gilman 1991. Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits. Science 254: 1500–1503.
  • Templeton, T. J., and S. D. Hauschka 1992. FGF-mediated aspects of skeletal muscle growth and differentiation are controlled by a high affinity receptor, FGFR1. Dev. Biol. 154: 169–181.
  • Touhara, K., J. Inglese, J. A. Pitcher, G. Shaw, and R. J. Lefkowitz 1994. Binding of G protein beta gamma-subunits to pleckstrin homology domains. J. Biol. Chem. 269: 10217–10220.
  • Ueda, Y., S. Hirai, S. Osada, A. Suzuki, K. Mizuno, and S. Ohno 1996. Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J. Biol. Chem. 271: 23512–23519.
  • van Biesen, T., B. E. Hawes, J. R. Raymond, L. M. Luttrell, W. J. Koch, and R. J. Lefkowitz 1996. G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism. J. Biol. Chem. 271: 1266–1269.
  • Vandenburgh, H. H., J. Shansky, R. Solerssi, and J. Chromiak 1995. Mechanical stimulation of skeletal muscle increases prostaglandin F2 alpha production, cyclooxygenase activity, and cell growth by a pertussis toxin sensitive mechanism. J. Cell. Physiol. 163: 285–294.
  • Xu, L., T. Sanchez, and C.-F. Zheng 1997. In vivo signal transduction pathway reporting systems. Strategies 10: 1–3.
  • Xu, N., O. Coso, D. Mahadevan, A. De Blasi, P. K. Goldsmith, W. F. Simonds, and J. S. Gutkind 1996. The PH domain of Ras-GAP is sufficient for in vitro binding to beta gamma subunits of heterotrimeric G proteins. Cell. Mol. Neurobiol. 16: 51–59.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.