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Cell Growth and Development

Thioredoxin Reductase Mediates Cell Death Effects of the Combination of Beta Interferon and Retinoic Acid

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Pages 6493-6504 | Received 12 Mar 1998, Accepted 03 Aug 1998, Published online: 28 Mar 2023

REFERENCES

  • Baichwal, V. R., and P. A. Baeuerle 1997. Activate NF-kappa B or die? Curr. Biol. 7: R94–R96.
  • Baker, A., C. M. Payne, M. M. Briehl, and G. Powis 1997. Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo. Cancer Res. 57: 5162–5167.
  • Barber, G. N., M. Wambach, S. Thompson, R. Jagus, and M. G. Katze 1995. Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation. Mol. Cell. Biol. 15: 3138–3146.
  • Bjornstedt, M., S. Kumar, and A. Holmgren 1995. Selenite and selenodiglutathione: reactions with thioredoxin systems. Methods Enzymol. 252: 209–219.
  • Boldin, M. P., T. M. Goncharov, Y. V. Goltsev, and D. Wallach 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85: 803–815.
  • Casso, D., and D. Beach 1996. A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 252: 518–529.
  • Chin, Y. E., M. Kitagawa, K. Kuida, R. A. Flavell, and X. Y. Fu 1997. Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol. Cell. Biol. 17: 5328–5337.
  • Chin, Y. E., M. Kitagawa, W. C. Su, Z. H. You, Y. Iwamoto, and X. Y. Fu 1996. Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272: 719–722.
  • Cohen, G. M., X. M. Sun, R. T. Snowden, D. Dinsdale, and D. N. Skilleter 1992. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem. J. 286: 331–334.
  • Darnell, J. E.Jr., I. M. Kerr, and G. R. Stark 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415–1421.
  • Deiss, L. P., E. Feinstein, H. Berissi, O. Cohen, and A. Kimchi 1995. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 9: 15–30.
  • Deiss, L. P., and A. Kimchi 1991. A genetic tool used to identify thioredoxin as a mediator of a growth inhibitory signal. Science 252: 117–120.
  • Dong, B., and R. H. Silverman 1995. 2-5A-dependent RNase molecules dimerize during activation by 2-5A. J. Biol. Chem. 270: 4133–4137.
  • Duhe, R. J., G. A. Evans, R. A. Erwin, R. A. Kirken, G. W. Cox, and W. L. Farrar 1998. Nitric oxide and thiol redox regulation of Janus kinase activity. Proc. Natl. Acad. Sci. USA 95: 126–131.
  • Gallegos, A., J. R. Gasdaska, C. W. Taylor, G. D. Paine-Murrieta, D. Goodman, P. Y. Gasdaska, M. Berggren, M. M. Briehl, and G. Powis 1996. Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells. Cancer Res. 56: 5765–5770.
  • Gasdaska, P. Y., J. R. Gasdaska, S. Cochran, and G. Powis 1995. Cloning and sequencing of a human thioredoxin reductase. FEBS Lett. 373: 5–9.
  • Glass, C. K., D. W. Rose, and M. G. Rosenfeld 1997. Nuclear receptor coactivators. Curr. Opin. Cell Biol. 9: 222–232.
  • Gutterman, J. U. 1994. Cytokine therapeutics: lessons from interferon a. Proc. Natl. Acad. Sci. USA 91: 1198–1205.
  • Hassel, B. A., A. Zhou, C. Sotomayor, A. Maran, and R. H. Silverman 1993. A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon. EMBO J. 12: 3297–3304.
  • Heppell-Parton, A., A. Cahn, A. Bench, N. Lowe, H. Lehrach, G. Zehetner, and P. Rabbitts 1995. Thioredoxin, a mediator of growth inhibition, maps to 9q31. Genomics 26: 379–381.
  • Hermeking, H., and D. Eick 1994. Mediation of c-Myc-induced apoptosis by p53. Science 265: 2091–2093.
  • Hirt, B. 1967. Selective extraction of polyoma DNA from infected mouse cell cultures. J. Mol. Biol. 26: 365–369.
  • Holmgren, A., and M. Bjornstedt 1995. Thioredoxin and thioredoxin reductase. Methods Enzymol. 252: 199–208.
  • Holmgren, A., and C. Lyckeborg 1980. Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase. Proc. Natl. Acad. Sci. USA 77: 5149–5152.
  • Holtschke, T., J. Lohler, Y. Kanno, T. Fehr, N. Giese, F. Rosenbauer, J. Lou, K. P. Knobeloch, L. Gabriele, J. Waring, M. F. Bachmann, R. M. Zinkernagel, H. C. Morse, K. Ozato, and I. Horak 1996. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 87: 307–317.
  • Hong, W. K., and L. M. Itri 1994. Retinoids and human cancer The retinoids: biology, chemistry and medicine2nd ed.Sporn, M. B., A. B. Roberts, and D. S. Goodman597–630Raven Press, New York, N.Y.
  • Kalvakolanu, D. V., S. K. Bandyopadhyay, M. L. Harter, and G. C. Sen 1991. Inhibition of interferon-inducible gene expression by adenovirus E1A proteins: block in transcriptional complex formation. Proc. Natl. Acad. Sci. USA 88: 7459–7463.
  • Kalvakolanu, D. V., and E. C. Borden 1996. An overview of the interferon system: signal transduction and mechanisms of action. Cancer Investig. 14: 25–53.
  • Kim, I. Y., and T. C. Stadtman 1997. Inhibition of NF-kappaB DNA binding and nitric oxide induction in human T cells and lung adenocarcinoma cells by selenite treatment. Proc. Natl. Acad. Sci. USA 94: 12904–12907.
  • Kimchi, A. 1998. DAP genes: novel apoptotic genes isolated by a functional approach to gene cloning. Biochim. Biophys. Acta 1377: F13–F33.
  • Kumar, A., M. Commane, T. W. Flickinger, C. M. Horvath, and G. R. Stark 1997. Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 278: 1630–1632.
  • Kumar, R., and I. Atlas 1992. Interferon alpha induces the expression of retinoblastoma gene product in human Burkitt lymphoma Daudi cells: role in growth regulation. Proc. Natl. Acad. Sci. USA 89: 6599–6603.
  • Laurent, A. G., B. Krust, J. Galabru, J. Svab, and A. G. Hovanessian 1985. Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cells. Proc. Natl. Acad. Sci. USA 82: 4341–4345.
  • Lindner, D. J., E. C. Borden, and D. V. Kalvakolanu 1997. Synergistic antitumor effects of a combination of interferons and retinoic acid on human tumor cells in vitro and in vivo. Clin. Cancer Res. 3: 931–937.
  • Machado, A. K., B. A. Morgan, and G. F. Merrill 1997. Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae. J. Biol. Chem. 272: 17045–17054.
  • Mangelsdorf, D. J., and R. M. Evans 1995. The RXR heterodimers and orphan receptors. Cell 83: 841–850.
  • Meissner, P. S., W. P. Sisk, and M. L. Berman 1987. Bacteriophage lambda cloning system for the construction of directional cDNA libraries. Proc. Natl. Acad. Sci. USA 84: 4171–4175.
  • Miranda-Vizuete, A., and G. Spyrou 1997. The novel oxidoreductase KDRF (KM-102-derived reductase-like factor) is identical with human thioredoxin reductase. Biochem. J. 325: 287–288.
  • Moore, D. M., D. V. Kalvakolanu, S. M. Lippman, J. J. Kavanagh, W. K. Hong, E. C. Borden, M. Paredes-Espinoza, and I. H. Krakoff 1994. Retinoic acid and interferon in human cancer: mechanistic and clinical studies. Semin. Hematol. 31: 31–37.
  • Muller, E. G. 1991. Thioredoxin deficiency in yeast prolongs S phase and shortens the G1 interval of the cell cycle. J. Biol. Chem. 266: 9194–9202.
  • Muzio, M., A. M. Chinnaiyan, F. C. Kischkel, K. O’Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J. D. Bretz, M. Zhang, R. Gentz, M. Mann, P. H. Krammer, M. E. Peter, and V. M. Dixit 1996. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85: 817–827.
  • Nolan-Sorden, N. L., K. Lesiak, B. Bayard, P. F. Torrence, and R. H. Silverman 1990. Photochemical crosslinking in oligonucleotide-protein complexes between a bromine-substituted 2-5A analog and 2-5A-dependent RNase by ultraviolet lamp or laser. Anal. Biochem. 184: 298–304.
  • Ossina, N. K., A. Cannas, V. C. Powers, P. A. Fitzpatrick, J. D. Knight, J. R. Gilbert, E. M. Shekhtman, L. D. Tomei, S. R. Umansky, and M. C. Kiefer 1997. Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression. J. Biol. Chem. 272: 16351–16357.
  • Packham, G., and J. L. Cleveland 1995. c-Myc and apoptosis. Biochim. Biophys. Acta 1242: 11–28.
  • Polyak, K., Y. Xia, J. L. Zweier, K. W. Kinzler, and B. Vogelstein 1997. A model for p53-induced apoptosis. Nature 389: 300–305.
  • Powis, G., M. Briehl, and J. Oblong 1995. Redox signalling and the control of cell growth and death. Pharmacol. Ther. 68: 149–173.
  • Raveh, T., A. G. Hovanessian, E. F. Meurs, N. Sonenberg, and A. Kimchi 1996. Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons. J. Biol. Chem. 271: 25479–25484.
  • Resnitzky, D., N. Tiefenbrun, H. Berissi, and A. Kimchi 1992. Interferons and interleukin 6 suppress phosphorylation of the retinoblastoma protein in growth-sensitive hematopoietic cells. Proc. Natl. Acad. Sci. USA 89: 402–406.
  • Rubartelli, A., N. Bonifaci, and R. Sitia 1995. High rates of thioredoxin secretion correlate with growth arrest in hepatoma cells. Cancer Res. 55: 675–680.
  • Samuel, C. E., K. L. Kuhen, C. X. George, L. G. Ortega, R. Rende-Fournier, and H. Tanaka 1997. The PKR protein kinase—an interferon-inducible regulator of cell growth and differentiation. Int. J. Hematol. 65: 227–237.
  • Savinova, O., and R. Jagus 1997. Use of vertical slab isoelectric focusing and immunoblotting to evaluate steady-state phosphorylation of eIF2 alpha in cultured cells. Methods 11: 419–425.
  • Schallreuter, K. U., and J. M. Wood 1987. Azelaic acid as a competitive inhibitor of thioredoxin reductase in human melanoma cells. Cancer Lett. 36: 297–305.
  • Schmidt, M., S. Nagel, J. Proba, C. Thiede, M. Ritter, J. F. Waring, F. Rosenbauer, D. Huhn, B. Wittig, I. Horak, and A. Neubauer 1998. Lack of interferon consensus sequence binding protein (ICSBP) transcripts in human myeloid leukemias. Blood 91: 22–29.
  • Schulze-Osthoff, K., H. Schenk, and W. Droge 1995. Effects of thioredoxin on activation of transcription factor NF-kappa B. Methods Enzymol. 252: 253–264.
  • Schulze-Osthoff, K., H. Walczak, W. Droge, and P. H. Krammer 1994. Cell nucleus and DNA fragmentation are not required for apoptosis. J. Cell Biol. 127: 15–20.
  • Schwartz, L. M., S. W. Smith, M. E. Jones, and B. A. Osborne 1993. Do all programmed cell deaths occur via apoptosis? Proc. Natl. Acad. Sci. USA 90: 980–984.
  • Scorsone, K. A., R. Panniers, A. G. Rowlands, and E. C. Henshaw 1987. Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis. J. Biol. Chem. 262: 14538–14543.
  • Sen, G. C., and R. M. Ransohoff 1997. Transcriptional regulation in the interferon system. Chapman & Hall and Landes Bioscience, Austin, Tex.
  • Silverman, R. H. 1997. 2-5A dependent Rnase L: a regulated endoribonuclease in the interferon system Ribonucleases: structure and functions. In: D’Alessio, G., and J. F. Riordan515–551Academic Press, Inc., New York, N.Y.
  • Skehan, P., R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J. T. Warren, H. Bokesch, S. Kenney, and M. R. Boyd 1990. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 82: 1107–1112.
  • Spyrou, G., M. Bjornstedt, S. Skog, and A. Holmgren 1996. Selenite and selenate inhibit human lymphocyte growth via different mechanisms. Cancer Res. 56: 4407–4412.
  • Studzinski, G. P. 1995. Cell growth and apoptosis: a practical approach. IRL Press, Oxford, United Kingdom.
  • Tagaya, Y., Y. Maeda, A. Mitsui, N. Kondo, H. Matsui, J. Hamuro, N. Brown, K. Arai, T. Yokota, H. Wakasugi, et al. 1989. ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin: possible involvement of dithiol-reduction in the IL-2 receptor induction. EMBO J. 8: 757–764.
  • Taniguchi, T., M. S. Lamphier, and N. Tanaka 1997. IRF1: the transcription factor linking interferon response and oncogenesis. Biochim. Biophys. Acta 1333: M9–M17.
  • Ucker, D. S., P. S. Obermiller, W. Eckhart, J. R. Apgar, N. A. Berger, and J. Meyers 1992. Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes. Mol. Cell. Biol. 12: 3060–3069.
  • Willman, C. L., C. E. Sever, M. G. Pallavicini, H. Harada, N. Tanaka, M. L. Slovak, H. Yamamoto, K. Harada, T. C. Meeker, A. F. List, and T. Taniguchi 1993. Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia. Science 259: 968–971.

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