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Cell Growth and Development

ASAP1, a Phospholipid-Dependent Arf GTPase-Activating Protein That Associates with and Is Phosphorylated by Src

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Pages 7038-7051 | Received 09 Jul 1998, Accepted 21 Aug 1998, Published online: 28 Mar 2023

REFERENCES

  • Alexandropoulos, K., and D. Baltimore 1996. Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin. Genes Dev. 10: 1341–1355.
  • Allen, C. M., C. M. Ely, M. A. Juaneza, and S. J. Parsons 1996. Activation of Fyn tyrosine kinase upon secretogogue stimulation of bovine chromaffin cells. J. Neurosci. Res. 44: 421–429.
  • Antonny, B., I. Huber, S. Paris, M. Chabre, and D. Cassel 1997. Activation of ADP-ribosylation factor 1 GTPase-activating protein by phosphatidylcholine-derived diacylglycerols. J. Biol. Chem. 272: 30848–30851.
  • Aoe, T., E. Cukierman, A. Lee, D. Cassel, P. J. Peters, and V. W. Hsu 1997. The KDEL receptor, ERD2, regulates intracellular traffic by recruiting a GTPase-activating protein for ARF1. EMBO J. 16: 7305–7316.
  • Barnekow, A., R. Jahn, and M. Schartl 1990. Synaptophysin: a substrate for the protein tyrosine kinase pp60c-src in intact synaptic vesicles. Oncogene 5: 1019–1024.
  • Barroso, M., and E. S. Sztul 1994. Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome. J. Cell Biol. 124: 83–100.
  • Bartel, P., C.-T. Chien, R. Sternglanz, and S. Fields 1993. Using the two-hybrid to detect protein-protein interactions Cellular interactions in development: a practical approach. In: Hartley, D. A.153–179Oxford University Press, Oxford, United Kingdom.
  • Boman, A. L., and R. A. Kahn 1995. Arf proteins: the membrane traffic police? Trends Biochem. Sci. 20: 147–150.
  • Bork, P. 1993. Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally? Proteins 17: 363–374.
  • Brown, H. A., S. Gutowski, C. R. Moomaw, C. Slaughter, and P. C. Sternweis 1993. ADP-ribosylation factor, a small GTP-dependent regulatory protein, activates phospholipase D. Cell 75: 1137–1144.
  • Brown, M. T. Unpublished results.
  • Brown, M. T., and J. A. Cooper 1996. Regulation, substrates and functions of src. Biochim. Biophys. Acta 1287: 121–149.
  • Cavenagh, M. M., J. A. Whitney, K. Carroll, C. Zhang, A. L. Bowman, A. G. Rosenwald, I. Mellman, and R. A. Kahn 1996. Intracellular distribution of Arf proteins in mammalian cells. Arf6 is uniquely localized to the plasma membrane. J. Biol. Chem. 271: 21767–21774.
  • Chardin, P., S. Paris, B. Antonny, S. Robineau, S. Beraud-Dufour, C. L. Jackson, and M. Chabre 1996. A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains. Nature 384: 481–484.
  • Cicchetti, P., B. J. Mayer, G. Thiel, and D. Baltimore 1992. Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. Science 257: 803–806.
  • Cockcroft, S., G. M. H. Thomas, A. Fensome, B. Geny, E. Cunningham, I. Gout, I. Hiles, N. F. Totty, O. Truong, and J. J. Hsuan 1994. Phospholipase D: a downstream effector of Arf in granulocytes. Science 263: 523–526.
  • Cooper, J. A., K. L. Gould, C. A. Cartwright, and T. Hunter 1986. Tyr527 is phosphorylated in pp60c-Src: implications for regulation. Science 231: 1431–1434.
  • Cox, M. E., C. M. Ely, A. D. Catling, M. J. Weber, and S. J. Parsons 1996. Tyrosine kinases are required for catecholamine secretion and mitogen-activated protein kinase activation in bovine adrenal chromaffin cells. J. Neurochem. 66: 1103–1112.
  • Cukierman, E., I. Huber, M. Rotman, and D. Cassel 1995. The ARF1 GTPase-activating protein: zinc finger motif and Golgi complex localization. Science 270: 1999–2002.
  • David-Pfeuty, T., and Y. Nouvian-Dooghe 1990. Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells. J. Cell Biol. 111: 3097–3116.
  • Ding, M., N. Vitale, S. C. Tsai, R. Adamik, J. Moss, and M. Vaughan 1996. Characterization of a GTPase-activating protein that stimulates GTP hydrolysis by both ADP-ribosylation factor (ARF) and ARF-like proteins. Comparison to the ARD1 gap domain. J. Biol. Chem. 271: 24005–24009.
  • Donaldson, J. G., R. A. Kahn, J. Lippincott-Schwartz, and R. D. Klausner 1991. Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein. Science 254: 1197–1199.
  • Donaldson, J. G., and R. D. Klausner 1994. ARF: a key regulatory switch in membrane traffic and organelle structure. Curr. Opin. Cell Biol. 6: 527–532.
  • Druker, B. J., H. J. Mamon, and T. M. Roberts 1989. Oncogenes, growth factors, and signal transduction. N. Engl. J. Med. 321: 1383–1391.
  • D’Souza-Schorey, C., G. Li, M. I. Colombo, and P. D. Stahl 1995. A regulatory role for ARF6 in receptor-mediated endocytosis. Science 267: 1175–1178.
  • D’Souza-Schorey, C., E. van Donselaar, V. W. Hsu, C. Yang, P. D. Stahl, and P. J. Peters 1998. ARF6 targets recycling vesicles to the plasma membrane: insights from an ultrastructural investigation. J. Cell Biol. 140: 603–616.
  • Evans, G. I., G. K. Lewis, G. Ramsay, and J. M. Bishop 1985. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5: 3610–3616.
  • Faundez, V., J. T. Horng, and R. B. Kelly 1997. ADP ribosylation factor 1 is required for synaptic vesicle budding in PC12 cells. J. Cell Biol. 138: 505–515.
  • Fensome, A., I. Cunningham, S. Prosser, S. K. Tan, P. Swigart, G. Thomas, J. Hsuan, and S. Cockcroft 1996. ARF and PITP restore GTP-gamma-S-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis. Curr. Biol. 6: 730–738.
  • Flynn, D. C., T.-H. Li, A. Reynolds, and J. T. Parsons 1993. Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate. Mol. Cell. Biol. 13: 7892–7900.
  • Foster-Barber, A., and J. M. Bishop 1998. Src interacts with dynamin and sysnapsin in neuronal cells. Proc. Natl. Acad. Sci. USA 95: 4673–4677.
  • Frank, S., S. Upender, S. H. Hansen, and J. E. Casanova 1998. ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6. J. Biol. Chem. 273: 23–27.
  • Fumagalli, S., N. F. Totty, J. J. Hsuan, and S. A. Courtneidge 1994. A target for Src in mitosis. Nature 368: 871–874.
  • Grandori, C., and H. Hanafusa 1988. p60c-src is complexed with a cellular protein in subcellular compartments involved in exocytosis. J. Cell Biol. 107: 2125–2135.
  • Hammonds-Odie, L. P., T. R. Jackson, A. A. Profit, I. J. Blader, C. W. Turck, G. D. Prestwich, and A. B. Theibert 1996. Identification and cloning of centaurin-α. J. Biol. Chem. 271: 18859–18868.
  • Hanks, S. K., and T. R. Polte 1997. Signaling through focal adhesion kinase. Bioessays 19: 137–145.
  • Hellman, U., C. Wernstedt, J. Gonez, and C. H. Heldin 1995. Improvement of an “In-Gel” digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing. Anal. Biochem. 224: 451–455.
  • Hollenberg, S. M., R. Sternglanz, P. F. Cheng, and H. Weintraub 1995. Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell. Biol. 15: 3813–3822.
  • Howell, B. W., F. B. Gertler, and J. A. Cooper 1997. Mouse disabled (mDab1): a Src binding protein implicated in neuronal development. EMBO J. 16: 121–131.
  • Huber, I., E. Cukierman, M. Rotman, T. Aoe, V. W. Hsu, and D. Cassel 1998. Requirement for both the amino terminal catalytic domain and a “non-catalytic” domain for in vivo activity of ADP-ribosylation factor GTPase-activating protein. J. Biol. Chem. 273: 24786–24791.
  • Hunziker, W., J. A. Whitney, and I. Mellman 1991. Selective inhibition of transcytosis by brefeldin A in MDCK cells. Cell 67: 617–627.
  • Ishino, M., T. Ohba, H. Sasaki, and T. Sasaki 1995. Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn. Oncogene 11: 2331–2338.
  • Janz, R., and T. C. Sudhof 1998. Cellugyrin, a novel ubiquitous form of synaptogyrin that is phosphorylated by pp60c-src. J. Biol. Chem. 273: 2851–2857.
  • Jiang, H., Z. Lu, J.-Q. Luo, A. Wolfman, and D. A. Foster 1995. Ras mediates the activation of phospholipase D by v-Src. J. Biol. Chem. 270: 6006–6009.
  • Kam, J., R. Aneja, J. Andrade, and P. A. Randazzo. 1998. Unpublished results.
  • Kaplan, K. B., J. R. Swedlow, H. E. Varmus, and D. O. Morgan 1992. Association of pp60c-src with endosomal membranes in mammalian fibroblasts. J. Cell Biol. 118: 321–333.
  • Klarlund, J. K., A. Guilherme, J. J. Holik, J. V. Virbasius, A. Chawla, and M. P. Czech 1997. Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains. Science 275: 1927–1930.
  • Klarlund, J. K., L. E. Rameh, L. C. Cantley, J. M. Buxton, J. J. Holik, C. Sakelis, V. Patki, S. Corvera, and M. P. Czech 1998. Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273: 1859–1862.
  • Knudsen, B. S., S. M. Feller, and H. Hanafusa 1994. Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk. J. Biol. Chem. 269: 32781–32787.
  • Knudsen, B. S., J. Zheng, S. M. Feller, J. P. Mayer, S. K. Burrell, D. Coxburn, and H. Hanafusa 1995. Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteins. EMBO J. 14: 2191–2198.
  • Kolanus, W., W. Nagel, B. Schiller, L. Zeitlmann, S. Godar, H. Stockinger, and B. Seed 1996. αLβ2 Integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule. Cell 86: 233–242.
  • Lane, W. S., A. Galat, M. W. Harding, and S. L. Schreiber 1991. Complete amino acid sequence of the FK506 and rapamycin binding protein, FKBP, isolated from calf thymus. J. Protein Chem. 10: 151–160.
  • Lemmon, M. A., and K. M. Ferguson 1998. Pleckstrin homology domains. Curr. Top. Microbiol. Immunol. 228: 39–74.
  • Linstedt, A. D., M. L. Vetter, J. M. Bishop, and R. B. Kelly 1992. Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicle. J. Cell Biol. 117: 1077–1084.
  • Lipsich, L. A., A. J. Lewis, and J. S. Brugge 1983. Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses. J. Virol. 48: 352–360.
  • Liscovitch, M., and L. C. Cantley 1995. Signal transduction and membrane traffic: the PITP/phosphoinositide connection. Cell 81: 659–662.
  • Makler, V., E. Cukierman, M. Rotman, A. Admon, and D. Cassel 1995. ADP-ribosylation factor-directed GTPase-activating protein. Purification and partial characterization. J. Biol. Chem. 270: 5232–5237.
  • Martin, A., F. D. Brown, M. N. Hodgkin, A. J. Bradwell, S. J. Cook, M. Hart, and M. J. O. Wakelam 1996. Activation of phospholipase D and phosphatidylinositol 4-phosphate 5-kinase in HL60 membranes is mediated by endogenous Arf but not Rho. J. Biol. Chem. 271: 17397–17903.
  • Martinez, R., B. Mathey-Prevot, A. Bernards, and D. Baltimore 1987. Neuronal pp60c-src contains a six-amino-acid insertion relative to its non-neuronal counterpart. Science 237: 411–415.
  • Meacci, E., S. C. Tsai, R. Adamik, J. Moss, and M. Vaughan 1997. Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor. Proc. Natl. Acad. Sci. USA 94: 1745–1748.
  • Moss, J., and M. Vaughan 1995. Structure and function of ARF proteins: activators of cholera toxin and critical components of intracellular vesicular transport processes. J. Biol. Chem. 270: 12327–12330.
  • Nagel, W., L. Zeitlmann, P. Schilcher, C. Geiger, J. Kolanus, and W. Kolanus 1998. Phosphoinositide 3-OH kinase activates the β2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1. J. Biol. Chem. 273: 14853–14861.
  • Nuoffer, C., and W. E. Balch 1994. GTPases: multifunctional molecular switches regulating vesicular traffic. Annu. Rev. Biochem. 63: 949–990.
  • Oddie, K. M., J. S. Litz, J. C. Balserak, D. M. Payne, C. E. Creutz, and S. J. Parsons 1989. Modulation of pp60c-src tyrosine kinase activity during secretion in stimulated bovine adrenal chromaffin cells. J. Neurosci. Res. 66: 1103–1112.
  • Onofri, F., S. Giovedi, P. Vaccaro, A. J. Czernik, F. Valtorta, C. P. De, P. Greengard, and F. Benfenati 1997. Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity. Proc. Natl. Acad. Sci. USA 94: 12168–12173.
  • Ooi, C. E., E. C. Dell’Angelica, and J. S. Bonifacino 1998. ADP-ribosylation factor 1 (ARF1) regulates recruitment of the AP-3 adaptor complex to membranes. J. Cell Biol. 142: 391–402.
  • Paris, S., S. Beraud-Dufour, S. Robineau, J. Bigay, B. Antonny, M. Chabre, and P. Chardin 1997. Role of protein-phospholipid interaction in the activation of Arf1 by the guanine nucleotide exchange factor Arno. J. Biol. Chem. 272: 22221–22226.
  • Parsons, J. T., and S. J. Parsons 1997. Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr. Opin. Cell Biol. 9: 187–192.
  • Parsons, S. J., and C. E. Creutz 1986. p60c-src activity detected in the chromaffin granule membrane. Biochem. Biophys. Res. Commun. 134: 736–742.
  • Pawson, T., and J. D. Scott 1997. Signaling through scaffold, anchoring, and adaptor proteins. Science 278: 2075–2080.
  • Peters, P. J., V. W. Hsu, C. E. Ooi, D. Finazzi, S. B. Teal, V. Oorschot, J. G. Donaldson, and R. D. Klausner 1995. Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments. J. Cell Biol. 128: 1003–1017.
  • Poon, P. P., X. Wang, M. Rotman, I. Huber, E. Cukierman, D. Cassel, R. A. Singer, and G. C. Johnston 1996. Saccharomyces cerevisiae Gcs1 is an ADP-ribosylation factor GTPase-activating protein. Proc. Natl. Acad. Sci. USA 93: 10074–10077.
  • Radhakrishna, H., and J. G. Donaldson 1997. ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway. J. Cell Biol. 139: 49–61.
  • Radhakrishna, H., R. D. Klausner, and J. G. Donaldson 1996. Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase. J. Cell Biol. 134: 935–947.
  • Rameh, L., A.-K. Arvidsson, Carraway K. L., III, A. D. Couvillon, G. Rathbun, A. Crompton, B. Van Renterghem, M. P. Czech, K. S. Ravichandran, S. J. Burakoff, D.-S. Wang, C.-S. Chen, and L. C. Cantley 1997. A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains. J. Biol. Chem. 272: 22059–22066.
  • Randazzo, P. A. 1997. Functional interaction of ADP-ribosylation factor 1 with phosphatidylinositol 4,5-bisphosphate. J. Biol. Chem. 272: 7688–7692.
  • Randazzo, P. A. 1997. Resolution of two ADP-ribosylation factor 1 GTPase-activating proteins from rat liver. Biochem. J. 324: 413–419.
  • Randazzo, P. A. Unpublished results.
  • Randazzo, P. A., and R. A. Kahn 1994. GTP hydrolysis by ADP-ribosylation factor is dependent on both an ADP-ribosylation factor GTPase-activating protein and acid phospholipids. J. Biol. Chem. 269: 10758–10763.
  • Randazzo, P. A., O. Weiss, and R. A. Kahn 1995. Preparation of recombinant ADP-ribosylation factor. Methods Enzymol. 257: 128–135.
  • Redmond, T., B. K. Brott, R. Jove, and M. J. Welsh 1992. Localization of the viral and cellular src kinases to perinuclear vesicles in fibroblasts. Cell Growth Differ. 3: 567–576.
  • Reichmann, C. T., B. J. Mayer, S. Keshav, and H. Hanafusa 1992. The product of the cellular Crk gene consists primarily of SH2 and SH3 regions. Cell Growth Differ. 3: 451–460.
  • Rickles, R. J., M. C. Botfield, X.-M. Zhou, P. A. Henry, J. S. Brugge, and M. J. Zoller 1995. Phage display selection of ligand residues important for Src homology 3 domain binding specificity. Proc. Natl. Acad. Sci. USA 92: 10909–10913.
  • Rothman, J. E. 1994. Mechanisms of intracellular protein transport. Nature 372: 55–63.
  • Rothman, J. E. 1996. The protein machinery of vesicle budding and fusion. Protein Sci. 5: 185–194.
  • Sakai, R., A. Iwamatsu, N. Hirano, S. Ogawa, T. Tanaka, H. Mano, Y. Yazaki, and H. Hirai 1994. A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMBO J. 16: 3748–3756.
  • Schekman, R., and L. Orci 1996. Coat proteins and vesicle budding. Science 271: 1526–1533.
  • Stokoe, D., L. Stephens, T. Copeland, P. R. J. Gafney, C. B. Reese, G. F. Painter, A. B. Holmes, F. McCormick, and P. T. Hawkins 1997. Dual role of phosphatidylinositol 3,4,5-trisphosphate in the activation of protein kinase B. Science 277: 567–570.
  • Tanaka, K., S. Imajoh-Ohmi, T. Sawada, R. Shirai, Y. Hashimoto, S. Iwasaki, K. Kaibuchi, Y. Kanaho, T. Shirai, Y. Terada, K. Kimura, S. Nagata, and Y. Fukui 1997. A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains. Eur. J. Biochem. 245: 512–519.
  • Taylor, T. C., R. A. Kahn, and P. Melancon 1992. Two distinct members of the ADP-ribosylation factor family of GTP-binding proteins regulate cell-free intra-Golgi transport. Cell 70: 69–79.
  • Thomas, S. M., and J. S. Brugge 1997. Cellular functions regulated by Src family kinases. Annu. Rev. Cell Dev. Biol. 13: 513–609.
  • Turner, D. L., and H. Weintraub 1995. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev. 8: 1434–1447.
  • Venkateswarlu, K., P. B. Oatey, J. M. Tavare, and P. J. Cullen 1998. Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase. Curr. Biol. 8: 463–466.
  • Vojtek, A. B., S. Hollenberg, and J. A. Cooper 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74: 205–214.
  • Ware, M. F., D. A. Tice, S. J. Parsons, and D. A. Lauffenburger 1997. Overexpression of cellular Src in fibroblasts enhances endocytic internalization of epidermal growth factor receptor. J. Biol. Chem. 272: 30185–30190.
  • Whitney, J. A., M. Gomez, D. Sheff, T. E. Kreis, and I. Mellman 1995. Cytoplasmic coat proteins involved in endosome function. Cell 83: 703–713.
  • Yu, H., J. K. Chen, S. Feng, D. C. Dalgarno, A. W. Brauer, and S. L. Schreiber 1994. Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 76: 933–945.

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