Localization of Atypical Protein Kinase C Isoforms into Lysosome-Targeted Endosomes through Interaction with p62

REFERENCES

• Akimoto, K., R. Takahashi, S. Moriya, N. Nishioka, J. Takayanagi, K. Kimura, Y. Fukui, S.-T. Osada, K. Mizuno, S.-I. Hirai, A. Kazlauskas, and S. Ohno 1996. EGF or PDGF receptors activate atypical PKCλ through phosphatidylinositol 3-kinase. EMBO J. 15: 788–798.
   PubMedGoogle Scholar
• Baier-Bitterlich, G., F. Überall, B. Bauer, F. Fresser, H. Wachter, H. Grunicke, G. Utermann, A. Altman, and G. Baier 1996. Protein kinase C-θ isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes. Mol. Cell. Biol. 16: 1842–1850.
   PubMedGoogle Scholar
• Bandyopadhyay, G., M. L. Standaert, L. Zhao, B. Yu, A. Avignon, L. Galloway, P. Karnam, J. Moscat, and R. V. Farese 1997. Activation of protein kinase C (α, β and ζ) by insulin in 3T3/L1 cells. J. Biol. Chem. 272: 2551–2558.
   PubMed Web of Science ®Google Scholar
• Beaufay, H., A. Amar-Costesec, and T. Feytmans 1974. Analytical study of microsomes and isolated subcellular membranes from rat liver. 3. Subfractionation of the microsomal fraction by isopycnic and differential centrifugation in density gradients. J. Cell Biol. 61: 188–200.
   PubMed Web of Science ®Google Scholar
• Berra, E., M. T. Diaz-Meco, I. Dominguez, M. M. Municio, L. Sanz, J. Lozano, R. S. Chapkin, and J. Moscat 1993. Protein kinase C ζ isoform is critical for mitogenic signal transduction. Cell 74: 555–563.
   PubMed Web of Science ®Google Scholar
• Berra, E., M. T. Diaz-Meco, J. Lozano, S. Frutos, M. M. Municio, P. Sanchez, L. Sanz, and J. Moscat 1995. Evidence for a role of MEK and MAPK during signal transduction by protein kinase Cζ. EMBO J. 14: 6157–6163.
   PubMedGoogle Scholar
• Berra, E., M. M. Municio, L. Sanz, S. Frutos, M. T. Diaz-Meco, and J. Moscat 1997. Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade. Mol. Cell. Biol. 17: 4346–4354.
   PubMed Web of Science ®Google Scholar
• Bjorkoy, G., A. Overvatn, M. T. Dı́az-Meco, J. Moscat, and T. Johansen 1995. Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolysing phospholipase C. J. Biol. Chem. 270: 21299–21306.
   PubMedGoogle Scholar
• Bjorkoy, G., M. Perander, A. Overvatn, and T. Johansen 1997. Reversion of Ras and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of λPKC is accompanied by the loss of constitutive nuclear MAPK/ERK activity. J. Biol. Chem. 272: 11557–11565.
   PubMedGoogle Scholar
• Chavrier, P., R. G. Parton, H. P. Hauri, K. Simons, and M. Zerial 1990. Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments. Cell 62: 317–329.
   PubMed Web of Science ®Google Scholar
• Csukai, M., C. H. Chen, M. A. De Matteis, and D. Mochly-Rosen 1997. The coatomer protein β′-COP, a selective binding protein (RACK) for protein kinase C epsilon. J. Biol. Chem. 272: 29200–29206.
   PubMed Web of Science ®Google Scholar
• Diaz-Meco, M. T., E. Berra, M. M. Municio, L. Sanz, J. Lozano, I. Dominguez, V. Diaz-Golpe, M. T. Lain de Lera, J. Alcami, C. V. Payá, F. Arenzana-Seisdedos, J. L. Virelizier, and J. Moscat 1993. A dominant negative protein kinase C ζ subspecies blocks NF-κB activation. Mol. Cell. Biol. 13: 4770–4775.
   PubMed Web of Science ®Google Scholar
• Diaz-Meco, M. T., J. Lozano, M. M. Municio, E. Berra, S. Frutos, L. Sanz, and J. Moscat 1994. Evidence for the in vitro and in vivo interaction of Ras with protein kinase C ζ. J. Biol. Chem. 269: 31706–31710.
   PubMedGoogle Scholar
• Diaz-Meco, M. T., M. M. Municio, P. Sanchez, J. Lozano, and J. Moscat 1996. Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype λ/ι and stimulates its kinase activity in vitro and in vivo. Mol. Cell. Biol. 16: 105–114.
   PubMed Web of Science ®Google Scholar
• Diaz-Meco, M. T., M. M. Municio, S. Frutos, P. Sanchez, J. Lozano, L. Sanz, and J. Moscat 1996. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 86: 777–786.
   PubMed Web of Science ®Google Scholar
• Dominguez, I., M. T. Diaz-Meco, M. M. Municio, E. Berra, A. Garcı́a de Herreros, M. E. Cornet, L. Sanz, and J. Moscat 1992. Evidence for a role of protein kinase C ζ subspecies in maturation of Xenopus laevis oocytes. Mol. Cell. Biol. 12: 3776–3783.
   PubMed Web of Science ®Google Scholar
• Dominguez, I., L. Sanz, F. Arenzana-Seisdedos, M. T. Diaz-Meco, J. L. Virelizier, and J. Moscat 1993. Inhibition of protein kinase C ζ subspecies blocks the activation of an NF-κB-like activity in Xenopus laevis oocytes. Mol. Cell. Biol. 13: 1290–1295.
   PubMedGoogle Scholar
• Duang-Fang, L., M. Brett, D. Nicholas, and C. B. Bradford 1997. Protein kinase C-ζ mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells. J. Biol. Chem. 279: 8146–8160.
   Google Scholar
• Evan, G. I., G. K. Lewis, G. Ramsay, and J. M. Bishop 1985. Isolation of monoclonal antibodies specific for human c-myc protooncogene product. Mol. Cell. Biol. 5: 3610–3616.
   PubMed Web of Science ®Google Scholar
• Exton, J. H. 1994. Phosphatidylcholine breakdown and signal transduction. Biochim. Biophys. Acta 1212: 26–42.
   PubMed Web of Science ®Google Scholar
• Feng, Y., B. Press, and A. Wandinger-Ness 1995. Rab 7: an important regulator of late endocytic membrane traffic. J. Cell Biol. 131: 1435–1452.
   PubMed Web of Science ®Google Scholar
• Folgueira, L., J. A. McElhinny, G. D. Bren, W. S. MacMorran, M. T. Diaz-Meco, J. Moscat, and C. V. Payá 1996. Protein kinase C-ζ mediates NF-κB activation in human immunodeficiency virus-infected monocytes. J. Virol. 70: 223–231.
   PubMedGoogle Scholar
• Franke, T. F., S.-H. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis 1995. The protein kinase encoded by the proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81: 727–736.
   PubMed Web of Science ®Google Scholar
• Fukuda, M. 1991. Lysosomal membrane glycoproteins. J. Biol. Chem. 266: 21327–21330.
   PubMed Web of Science ®Google Scholar
• Gómez, J., A. Garcı́a, L. R. Borlado, P. Bonay, C. Martı́nez-A, A. Silva, M. Fresno, A. C. Carrera, C. Eicher-Streiber, and A. Rebollo 1997. IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-ζ. J. Immunol. 158: 1516–1522.
   PubMedGoogle Scholar
• Goodnight, J., H. Mischak, W. Kolch, and J. F. Mushinski 1995. Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. J. Biol. Chem. 270: 9991–10001.
   PubMed Web of Science ®Google Scholar
• Gruenberg, J., G. Griffiths, and K. E. Howell 1989. Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro. J. Cell Biol. 108: 1301–1316.
   PubMed Web of Science ®Google Scholar
• Hannun, Y. A. 1994. The sphingomyelin cycle and the second messenger function of ceramide. J. Biol. Chem. 269: 3125–3128.
   PubMed Web of Science ®Google Scholar
• Howe, L. R., S. J. Leevers, N. Gomez, S. Nakielny, P. Cohen, and C. J. Marshall 1992. Activation of MAP kinase pathway by the protein kinase Raf. Cell 71: 335–342.
   PubMed Web of Science ®Google Scholar
• Huang, C., W. Ma, G. T. Bowden, and Z. Dong 1996. Ultraviolet B-induced activated protein-1 activation does not require epidermal growth factor receptor but it is blocked by a dominant negative PKCλ/ι. J. Biol. Chem. 271: 31262–31268.
   PubMed Web of Science ®Google Scholar
• Joung, I., J. L. Strominger, and J. Shin 1996. Molecular cloning of a phosphotyrosine-independent ligand of the p56lckSH2 domain. Proc. Natl. Acad. Sci. USA 93: 5991–5995.
   PubMed Web of Science ®Google Scholar
• Katz, M. E., and F. McCormick 1997. Signal transduction from multiple Ras effectors. Curr. Opin. Genet. Dev. 7: 75–79.
   PubMed Web of Science ®Google Scholar
• Kolesnick, R., and D. W. Golde 1994. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77: 325–328.
   PubMed Web of Science ®Google Scholar
• Kuroda, S., C. Tokunaga, Y. Kiyohara, O. Higuchi, H. Konishi, K. Mizuno, G. N. Gill, and U. Kikkawa 1996. Protein-protein interaction of zinc finger LIM domains with protein kinase C. J. Biol. Chem. 271: 31029–31032.
   PubMed Web of Science ®Google Scholar
• Limatola, C., B. Barabino, A. Nista, and A. Santoni 1997. Interleukin 1-β-induced protein kinase C-ζ activation is mimicked by exogenous phospholipase D. Biochem. J. 321: 497–501.
   PubMedGoogle Scholar
• Liscovitch, M., and L. C. Cantley 1994. Lipid second messengers. Cell 77: 329–334.
   PubMed Web of Science ®Google Scholar
• Lozano, J., E. Berra, M. M. Municio, M. T. Diaz-Meco, I. Dominguez, L. Sanz, and J. Moscat 1994. Protein kinase C isoform is critical for κB-dependent promoter activation by sphingomyelinase. J. Biol. Chem. 269: 19200–19202.
   PubMed Web of Science ®Google Scholar
• Mendez, R., M. F. White, M. G. Myers, and R. E. Rhoads 1997. IRS-1-mediated activation of protein kinase C ζ is required for the stimulation of protein synthesis by insulin. Mol. Cell. Biol. 17: 5184–5192.
   PubMedGoogle Scholar
• Mochly-Rosen, D., H. Khaner, and J. López 1991. Identification of intracellular receptors for activated protein kinase C. Proc. Natl. Acad. Sci. USA 88: 3997–4000.
   PubMed Web of Science ®Google Scholar
• Moriya, S., A. Kazlauskas, K. Akimoto, S.-I. Hirai, K. Mizuno, T. Takenawa, Y. Fukui, Y. Watanabe, S. Ozaki, and S. Ohno 1996. Platelet-derived growth factor activates protein kinase Cɛ through redundant and independent signaling pathways involving phospholipase Cγ or phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA 93: 151–155.
   PubMed Web of Science ®Google Scholar
• Muller, G., M. Ayoub, P. Storz, J. Rennecke, D. Fabbro, and K. Pfizenmaier 1995. PKCζ is a molecular switch in signal transduction of TNFα, bifunctionally regulated by ceramide and arachidonic acid. EMBO J. 14: 1961–1969.
   PubMedGoogle Scholar
• Municio, M. M., J. Lozano, J. Moscat, and M. T. Dı́az-Meco 1995. Identification of heterogeneous ribonucleoprotein A1 as a novel substrate for protein kinase C ζ. J. Biol. Chem. 270: 15884–15891.
   PubMedGoogle Scholar
• Nakanishi, H., K. A. Brewer, and J. H. Exton 1993. Activation of the isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268: 13–16.
   PubMed Web of Science ®Google Scholar
• Nishizuka, Y. 1992. Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C. Science 258: 607–614.
   PubMed Web of Science ®Google Scholar
• Novick, P., and M. Zerial 1997. The diversity of Rab proteins in vesicle transport. Curr. Opin. Cell Biol. 9: 496–504.
   PubMed Web of Science ®Google Scholar
• Ohno, Y., T. Fuji, K. Ogita, U. Kikkawa, K. Igarashi, and Y. Nishizuka 1989. Protein kinase C ζ subspecies from rat brain: its structure, expression, and properties. Proc. Natl. Acad. Sci. USA 86: 3099–3103.
   PubMedGoogle Scholar
• Okano, I., J. Hiraoka, H. Otera, K. Nunoue, K. Ohashi, S. Iwashita, M. Hirai, and K. Mizuno 1995. Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs. J. Biol. Chem. 270: 31321–31330.
   PubMedGoogle Scholar
• Palmer, R., L. V. Dekker, R. Woscholski, J. A. Le Good, R. Gigg, and P. Parker 1995. Activation of PRK1 by phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 270: 22412–22416.
   PubMedGoogle Scholar
• Puls, A., S. Schmidt, F. Grawe, and S. Stabel 1997. Interaction of protein kinase C ζ with ZIP, a novel protein kinase C-binding protein. Proc. Natl. Acad. Sci. USA 94: 6191–6196.
   PubMed Web of Science ®Google Scholar
• Quest, A. F. G., and R. M. Bell 1994. The regulatory region of protein kinase Cγ. J. Biol. Chem. 269: 20000–20012.
   PubMed Web of Science ®Google Scholar
• Ron, D., C.-H. Chen, J. Caldwell, L. Jamieson, E. Orr, and D. Mochly-Rosen 1994. Cloning of an intracellular receptor for protein kinase C: a homolog of the β subunit of G protein. Proc. Natl. Acad. Sci. USA 91: 839–843.
   PubMed Web of Science ®Google Scholar
• Rzymkiewicz, D. M., T. Tetsuka, D. Daphna-Iken, S. Srivastava, and A. R. Morrison 1996. Interleukin-1β activates protein kinase Cζ in renal mesangial cells. J. Biol. Chem. 271: 17241–17246.
   PubMedGoogle Scholar
• Sacktor, T. C., P. Osten, P. Valsamis, X. Jiang, M. U. Naik, and E. Sublette 1993. Persistent activation of the ζ isoform of protein kinase C in the maintenance of long-term potentiation. Proc. Natl. Acad. Sci. USA 90: 8342–8346.
   PubMed Web of Science ®Google Scholar
• Sagata, N., M. Oskarsson, T. Copeland, J. Brumbaugh, and F. Vande Woude 1988. Function of c-mos protooncogene product in meiotic maturation in Xenopus oocytes. Nature 335: 519–525.
   PubMed Web of Science ®Google Scholar
• Sanchez, P., et al. Unpublished data.
   Google Scholar
• Sells, S. F., D. P. Wood, S. S. Joshi-Barve, S. Muthukumar, R. J. Jacob, S. A. Crist, S. Humphreys, and V. M. Rangnekar 1994. Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells. Cell Growth Differ. 5: 457–466.
   PubMedGoogle Scholar
• Shpetner, H., M. Joly, D. Hartley, and S. Corvera 1996. Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J. Cell Biol. 132: 595–605.
   PubMedGoogle Scholar
• Sontag, E., J. M. Sontag, and A. Garcia 1997. Protein phosphatase 2A is a critical regulator of protein kinase C ζ signaling targeted by SV40 small t to promote cell growth and NF-κB activation. EMBO J. 16: 5662–5671.
   PubMed Web of Science ®Google Scholar
• Toker, A., M. Meyer, K. K. Reddy, J. R. Falck, R. Aneja, S. Aaneja, A. Parra, D. J. Burns, L., M. Ballas, and L. C. Cantley 1994. Activation of protein kinase C family members by the novel polyphosphoimositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3. J. Biol. Chem. 269: 32358–32367.
   PubMed Web of Science ®Google Scholar
• Van Dijk, M. C. M., F. J. G. Muriana, P. C. J. van der Hoeven, J. Widt, D. Schaap, W. H. Moolenaar, and W. J. van Blitterswijk 1997. Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: dependence on protein kinase C-ζ. Biochem. J. 323: 693–699.
   PubMedGoogle Scholar
• Ways, D. K., K. Posekany, J. Devente, T. Garris, J. M. Chen, J. Hooker, W. X. Qin, P. Cook, D. Fletcher, and P. Parker 1994. Overexpression of protein kinase C-ζ stimulates leukemic cell differentiation. Cell Growth Differ. 5: 1195–1203.
   PubMedGoogle Scholar
• Westermann, P., M. Knoslich, O. Maier, C. Lindschan, and H. Haller 1996. Protein kinase C bound to the Golgi apparatus supports the formation of constitutive transport vesicles. Biochem. J. 320: 651–658.
   PubMedGoogle Scholar
• Wooten, M. W., G. Zhou, M. L. Seibenhener, and E. S. Coleman 1994. A role for ζ protein kinase C in nerve growth factor induced differentiation of PC12 cells. Cell Growth Differ. 5: 395–403.
   PubMedGoogle Scholar
• Wooten, M. W., M. L. Seibenhener, L. H. Matthews, G. Zhou, and E. S. Coleman 1996. Modulation of ζ-protein kinase C by cyclic AMP in PC12 cells occurs through phosphorylation by protein kinase A. J. Neurochem. 67: 1023–1031.
   PubMedGoogle Scholar
• Xu, J., M. M. Zutter, S. A. Santoro, and R. Clark 1996. PDGF-induction of α2 integrin gene expression is mediated by protein kinase C ζ. J. Cell Biol. 134: 1301–1311.
   PubMedGoogle Scholar
• Xu, J., and R. Clark 1997. A three-dimensional collagen lattice induces protein kinase C-ζ activity. Role in α2 integrin and collagenase mRNA expression. J. Cell Biol. 136: 473–483.
   PubMed Web of Science ®Google Scholar
• Yao, B., Y. Zhang, S. Delikat, S. Mathias, S. Basu, and R. N. Kolesnick 1995. Phosphorylation of Raf by ceramide-activated protein kinase. Nature 378: 307–310.
   PubMed Web of Science ®Google Scholar
• Zhang, Y., and R. N. Kolesnick 1995. Editorial: signalling through the sphingomyelin pathway. Endocrinology 136: 4157–4159.
   PubMedGoogle Scholar