14
Views
58
CrossRef citations to date
0
Altmetric
DNA Dynamics and Chromosome Structure

Concurrent Replication and Methylation at Mammalian Origins of Replication

, , , &
Pages 3475-3482 | Received 30 Jun 1997, Accepted 12 Mar 1998, Published online: 28 Mar 2023

REFERENCES

  • Adams, R. L., E. L. McKay, L. M. Craig, and R. H. Burdon 1979. Mouse DNA methylase: methylation of native DNA. Biochim. Biophys. Acta 561: 345–357.
  • Baylin, S. B., M. Makos, J. J. Wu, R. W. Yen, A. de Bustros, P. Vertino, and B. D. Nelkin 1991. Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression. Cancer Cells 3: 383–390.
  • Belinsky, S. A., K. J. Nikula, S. B. Baylin, and J. P. J. Issa 1996. Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer. Proc. Natl. Acad. Sci. USA 93: 4045–4050.
  • Bergamn, A. D., and M. Johnson 1992. The HeLa Pur factor binds single-stranded DNA and a specific element conserved in gene flanking regions and origins of DNA replication. Mol. Cell. Biol. 12: 1257–1265.
  • Boye, E., and A. Lobner-Olesen 1990. The role of dam methyltransferase in the control of DNA replication in E. coli. Cell 62: 981–989.
  • Campbell, J. L., and N. Kleckner 1990. E. coli oriC and the dnaA gene promoter are sequestered from the dam methyltransferase following passage of the chromosomal replication fork. Cell 62: 967–979.
  • Clark, S. J., J. Harrison, C. L. Paul, and M. Frommer 1994. High sensitivity mapping of methylated cytosines. Nucleic Acids Res. 22: 2990–2997.
  • Chuang, L. S.-H., H.-I. Ian, T.-W. Koh, H.-H. Ng, G. Xu, and B. F. L. Li 1997. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21waf1. Science 277: 1996–2000.
  • el-Deiry, W. S., B. D. Nelkin, P. Celano, R. W. Yen, J. P. Falco, S. R. Hamilton, and S. B. Baylin 1991. High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer. Proc. Natl. Acad. Sci. USA 88: 3470–3474.
  • Gruenbaum, Y., M. Szyf, H. Cedar, and A. Razin 1983. Methylation of replicating and post-replicated mouse L-cell DNA. Proc. Natl. Acad. Sci. USA 80: 4919–4921.
  • Hirt, B. 1967. Selective extraction of polyoma DNA from infected mouse cell cultures. J. Mol. Biol. 26: 365–369.
  • Kaufmann, G., M. Zannis-Hadjopoulos, and R. G. Martin 1985. Cloning of nascent monkey DNA synthesized early in cell cycle. Mol. Cell. Biol. 5: 721–727.
  • Kautiainen, T. L., and P. A. Jones 1986. DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture. J. Biol. Chem. 261: 1594–1598.
  • Kitsberg, D., S. Selig, I. Keshet, and H. Cedar 1993. Replication structure of the human β-globin gene domain. Nature 366: 588–590.
  • Kumar, S., M. Giacca, P. Nori, G. Biamonti, S. Riva, and A. Falaschi 1996. Utilization of the same DNA replication origin by human cells of different derivation. Nucleic Acids Res. 24: 3289–3294.
  • Laird, P. W., L. Jacksongrusby, A. Fazeli, S. L. Dickinson, W. E. Jung, E. Li, R. A. Weinberg, and R. Jaenisch 1995. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81: 197–205.
  • Leonhardt, H., A. W. Page, H.-U. Weier, and T. Bestor 1992. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71: 865–873.
  • Li, E., T. H. Bestor, and R. Jaenisch 1992. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69: 915–926.
  • MacLeod, A. R., and M. Szyf 1995. Expression of an antisense to the DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis. J. Biol. Chem. 270: 8037–8043.
  • Merlo, A., J. G. Herman, L. Mao, D. J. Lee, E. Gabrielson, P. Burger, S. B. Baylin, and D. Sidransky 1995. 5′ CpG islands methylation is associated with transcription silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers. Nature Med. 1: 686–692.
  • Modrich, P. 1987. DNA mismatch correction. Annu. Rev. Biochem. 56: 435–466.
  • Moschones, N., E. Boer, and R. A. Flavell 1982. The DNA sequence of the 5′ flanking region of the human β-globin gene: evolutionary conservation and polymorphic differences. Nucleic Acids Res. 10: 2109–2128.
  • Nelkin, B. D., D. Przepiorka, P. J. Burke, E. D. Thomas, and S. B. Baylin 1991. Abnormal methylation of the calcitonin gene marks progression of chronic myelogenous leukemia. Blood 77: 2431–2434.
  • Ramchandani, S., R. A. MacLeod, M. Pinard, E. von Hofe, and M. Szyf 1997. Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide. Proc. Natl. Acad. Sci. USA 94: 684–689.
  • Razin, A., and H. Cedar 1991. DNA methylation and gene expression. Microbiol. Rev. 55: 451–458.
  • Razin, A., E. Feldmesser, T. Kafri, and M. Szyf 1985. Cell specific DNA methylation and a nucleosome locking model for their function. Prog. Clin. Biol. Res. 198: 239–253.
  • Razin, A., and A. D. Riggs 1980. DNA methylation and gene function. Science 210: 604–610.
  • Rein, T., H. Zorbas, and M. DePamphilis 1997. Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides. Mol. Cell. Biol. 17: 416–426.
  • Roberts, D., B. C. Hoopes, W. R. McClure, and N. Kleckner 1985. IS10 transposition is regulated by DNA adenine methylation. Cell 43: 117–130.
  • Szyf, M. 1996. The DNA methylation machinery as a target for anticancer therapy. Pharmacol. Ther. 70: 1–37.
  • Szyf, M., K. Avraham-Haetzni, A. Reifman, J. Shlomai, F. Kaplan, A. Oppenheim, and A. Razin 1984. DNA methylation pattern is determined by the intracellular level of the methylase. Proc. Natl. Acad. Sci. USA 81: 3278–3282.
  • Szyf, M., V. Bozovic, and G. Tanigawa 1991. Growth regulation of mouse DNA methyltransferase gene expression. J. Biol. Chem. 266: 10027–10030.
  • Szyf, M., J. Theberge, and V. Bozovic 1995. Ras induces a general DNA demethylation activity in mouse embryonal P19 cells. J. Biol. Chem. 270: 12690–12696.
  • Tao, L., T. Nielsen, P. Friedlander, M. Zannis-Hadjopoulos, and G. Price 1997. Differential DNA replication origin activities in human normal skin fibroblast and HeLa cell lines. J. Mol. Biol. 273: 509–518.
  • Tasheva, E. S., and D. J. Roufa 1994. Densely methylated DNA islands in mammalian chromosomal replication origins. Mol. Cell. Biol 14: 5636–5644.
  • Tate, P. H., and A. P. Bird 1993. Effects of DNA methylation on DNA-binding proteins and gene expression. Curr. Opin. Gen. Dev. 3: 226–231.
  • Vassilev, L. T., and E. M. Johnson 1990. An initiation zone of chromosomal DNA replication located upstream of the c-myc gene in proliferating HeLa cells. Mol. Cell. Biol. 10: 4685–4689.
  • Wilson, V. L., and P. A. Jones 1983. Inhibition of DNA methylation by chemical carcinogens in vitro. Cell 32: 239–246.
  • Woodcock, D. M., P. J. Crowther, and W. P. Diver 1987. The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide. Biochem. Biophys. Res. Commun. 145: 888–894.
  • Woodcock, D. M., D. L. Simmons, P. J. Crowther, L. A. Cooper, K. J. Trainor, and A. A. Morley 1986. Delayed DNA methylation is an integral feature of DNA replication in mammalian cells. Exp. Cell. Res. 166: 102–112.
  • Wu, J., J. P. Issa, J. Herman, Bassett D. E., Jr., B. D. Nelkin, and S. B. Baylin 1993. Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH3T3 cells. Proc. Natl. Acad. Sci. USA 90: 8891–8895.
  • Zannis-Hadjopoulos, M., M. Perisco, and R. G. Martin 1981. The remarkable instability of replication loops provides a general method for isolation of origins of replication. Cell 27: 155–163.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.