26
Views
104
CrossRef citations to date
0
Altmetric
Cell Growth and Development

L-DNase II, a Molecule That Links Proteases and Endonucleases in Apoptosis, Derives from the Ubiquitous Serpin Leukocyte Elastase Inhibitor

, , , , , & show all
Pages 3612-3619 | Received 02 Jan 1998, Accepted 04 Mar 1998, Published online: 28 Mar 2023

REFERENCES

  • Barry, M. A., and A. Eastman 1993. Identification of deoxyribonuclease II as an endonuclease involved in apoptosis. Arch. Biochem. Biophys. 300: 440–450.
  • Bellamy, C. O. C., R. D. G. Malcomson, D. J. Harrison, and A. H. Wyllie 1995. Cell death in health and disease: the biology and regulation of apoptosis. Semin. Cancer Biol. 6: 3–16.
  • Bernardi, G., A. Bernardi, and A. Chersi 1966. Studies on acid hydrolases. I. A procedure for the preparation of acid deoxyribonuclease and other acid hydrolases. Biochim. Biophys. Acta 129: 1–11.
  • Chinnaiyan, A. M., and V. M. Dixit 1996. The cell death machine. Curr. Biol. 6: 555–562.
  • Christensen, S., Z. Valnickova, I. B. Thögersen, S. V. Pizzo, H. R. Nielsen, P. Roepstorff, and J. J. Enghild 1995. Sodium dodecyl sulfate-stable complexes between serpins and active or inactive proteinases contain the region COOH-terminal to the reactive site loop. J. Biol. Chem. 270: 14859–14862.
  • Gettins, P., P. Patston, and S. Olson 1996. Serpins: structure, function and biology. Springer Editor, New York, N.Y.
  • Kawabata, H., N. Anzai, H. Masutani, T. Hirama, T. Hishita, M. Dodo, T. Masuda, Y. Yoshida, and M. Okuma 1997. Mg2+- or Mn2+-dependent endonuclease activities of human myeloid leukemia cells capable of producing nucleosomal-size DNA fragmentation. Biochem. Biophys. Res. Commun. 233: 133–138.
  • Kawabata, H., N. Anzai, H. Masutani, T. Hirama, Y. Yoshida, and M. Okuma 1993. Detection of Mg2+-dependent endonuclease activity in myeloid leukemia cell nuclei capable of producing internucleosomal DNA cleavage. Biochem. Biophys. Res. Commun. 191: 247–254.
  • Kordula, T., A. Dubin, H. Schooltink, A. Koj, P. C. Heinrich, and S. Rose-John 1993. Molecular cloning and expression of an intracellular serpin: an elastase inhibitor from horse leukocytes. Biochem. J. 293: 187–193.
  • Korpula-Mastalerz, R., and A. Dubin 1996. The intracellular serpin family. Acta Biochim. Pol. 43: 419–430.
  • Kroemer, G. 1997. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3: 614–620.
  • Lawrence, D. A. 1997. The serpin-proteinase complex revealed. Nat. Struct. Biol. 4: 339–341.
  • Lei, H. Y., M. J. Tang, and N. Tsao 1997. Intracellular alkalinization in dexamethasone-induced thymocyte apoptosis. Apoptosis 2: 304–312.
  • Liao, T.-H. 1985. The subunit structure and active site sequence of porcine spleen deoxyribonuclease. J. Biol. Chem. 260: 10708–10713.
  • Liao, T.-H., W.-C. Liao, H.-C. Chang, and K.-S. Lu 1989. Deoxyribonuclease II purified from the isolated lysosomes of porcine spleen and from porcine liver homogenates. Comparison with deoxyribonuclease II purified from porcine spleen homogenates. Biochim. Biophys. Acta 1007: 15–22.
  • Montague, J. W., M. L. Gaido, C. Frye, and J. A. Cidlowski 1994. A calcium-dependent nuclease from apoptotic rat thymocytes is homologous with cyclophilin. Recombinant cyclophilins A, B, C have nuclease activity. J. Biol. Chem. 269: 18877–18880.
  • Novagen Inc. 1995. pET system manual6th ed. Novagen Inc., Madison, Wis.
  • Pandey, S., P. R. Walker, and M. Sikorska 1997. Identification of a novel 97 kDa endonuclease capable of internucleosomal DNA cleavage. Biochemistry 36: 711–720.
  • Pardhasaradhi, B. V. V., A. Khar, and U. K. Srinivas 1997. Effect of anti-apoptotic genes and peptide inhibitors on cytoplasmic acidification during apoptosis. FEBS Lett. 411: 67–70.
  • Patel, T., G. J. Gores, and S. H. Kaufmann 1996. The role of proteases during apoptosis. FASEB J. 10: 587–597.
  • Peitsch, M. C., B. Polzar, H. Stephan, T. Crompton, H. R. MacDonald, H. G. Mannherz, and J. Tschopp 1993. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J. 12: 371–377.
  • Pemberton, P. A. 1997. The role of serpin superfamily members in cancer. Cancer J. 10: 24–30.
  • Pérez-Sala, D., D. Collado-Escobar, and F. Mollinedo 1995. Intracellular alkalinization suppresses Lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease. J. Biol. Chem. 270: 6235–6242.
  • Potempa, J., A. Dubin, W. Watorek, and J. Travis 1988. An elastase inhibitor from equine leukocyte cytosol belongs to serpin superfamily. Further characterization and amino acid sequence of the reactive center. J. Biol. Chem. 263: 7364–7369.
  • Promega Corp. 1996. TNT coupled retyculocyte lysate system. Technical bulletin. Promega Corp., Madison, Wis.
  • Remold-O’Donnell, E., J. Chin, and M. Alberts 1992. Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor. Proc. Natl. Acad. Sci. USA 89: 5635–5639.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis 1989. Molecular cloning: a laboratory manual2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Shak, S., D. J. Capon, R. Hellmiss, S. A. Marsters, and C. L. Baker 1990. Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum. Proc. Natl. Acad. Sci. USA 87: 9188–9192.
  • Shiokawa, D., H. Ohyama, T. Yamada, K. Takahashi, and S.-I. Tanuma 1994. Identification of an endonuclease responsible for apoptosis in rat thymocytes. Eur. J. Biochem. 226: 23–30.
  • Stein, P. E., A. G. W. Leslie, J. T. Finch, W. G. Turnell, P. J. McLaughlin, and R. W. Carrell 1990. Cristal structure of ovalbumin as a model for reactive centre of serpins. Nature 347: 99–102.
  • Teschauer, W. F., R. Mentele, and C. P. Sommerhoff 1993. Primary structure of a porcine leukocyte serpin. Eur. J. Biochem. 217: 519–526.
  • Torriglia, A., E. Chaudun, F. Chany-Fournier, J. C. Jeanny, Y. Courtois, and M. F. Counis 1995. Involvement of DNase II in nuclear degeneration during lens cell differentiation. J. Biol. Chem. 270: 28579–28585.
  • Wolf, C. M., S. J. Morana, and A. Eastman 1997. Zinc inhibits apoptosis upstream of ICE/CED-3 proteases rather than at the level of an endonuclease. Cell Death Differ. 4: 125–129.
  • Wright, S. C., Q. S. Wei, J. Zhong, H. Zheng, D. H. Kinder, and J. W. Larrick 1994. Purification of a 24kDa protease from apoptotic tumor cells that activates DNA fragmentation. J. Exp. Med. 180: 2113–2123.
  • Xu, M.-Q., and F. B. Perler 1996. The mechanism of protein splicing and its modulation by maturation. EMBO J. 15: 5146–5153.
  • Yamanaka, M., Y. Tsubota, M. Anai, K. Ishimatsu, M. Okumura, S. Katsuki, and Y. Takagi 1974. Thermal inactivation of shrimp deoxyribonuclease with and without sodium dodecyl sulfate. J. Biol. Chem. 249: 3884–3889.
  • Yasuda, T., D. Nadano, S. Awazu, and K. Kishi 1992. Human urine deoxyribonuclease II (DNase II) isoenzymes: a novel immunoaffinity purification, biochemical multiplicity, genetic heterogeneity and broad distribution among tissues and body fluids. Biochim. Biophys. Acta 1119: 185–193.
  • Zeng, Z., D. Parmelee, H. Hyaw, T. A. Coleman, K. Su, J. Zhang, R. Gentz, S. Ruben, C. Rose, and Y. Li 1997. Cloning and characterization of a novel human DNase. Biochem. Biophys. Res. Commun. 231: 499–504.
  • Zhivotovsky, B., D. H. Burgess, and S. Orrenius 1996. Proteases in apoptosis. Experientia 52: 968–978.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.