REFERENCES
- Adra, C. N., P. H. Boer, and M. W. McBurney 1987. Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter. Gene 60: 65–74.
- Belmaaza, A., and P. Chartrand 1994. One-sided invasion events in homologous recombination at double-strand breaks. Mutat. Res. 314: 199–208.
- Bollag, R. J., D. R. Elwood, E. D. Tobin, A. R. Godwin, and R. M. Liskay 1992. Formation of heteroduplex DNA during mammalian intrachromosomal gene conversion. Mol. Cell. Biol. 12: 1546–1552.
- Brenneman, M., F. S. Gimble, and J. H. Wilson 1996. Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases. Proc. Natl. Acad. Sci. USA 93: 3608–3612.
- Chen, C., and H. Okayama 1987. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7: 2745–2752.
- Choulika, A., A. Perrin, B. Dujon, and J. F. Nicolas 1995. Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 1968–1973.
- Colleaux, L., L. D’Auriol, F. Galibert, and B. Dujon 1988. Recognition and cleavage site of the intron-encoded omega transposase. Proc. Natl. Acad. Sci. USA 85: 6022–6026.
- Doetschman, T., R. G. Gregg, N. Maeda, M. L. Hooper, D. W. Melton, S. Thompson, and O. Smithies 1987. Targeted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature 330: 576–578.
- Donoho, G. P. 1996. Ph.D. thesis. Stanford University, Stanford, Calif.
- Elliott, B., C. Richardson, J. Winderbaum, J. A. Nickoloff, and M. Jasin 1998. Gene conversion tracts from double-strand break repair in mammalian cells. Mol. Cell. Biol. 18: 93–101.
- Esposito, M. S. 1971. Postmeiotic segregation in Saccharomyces. Mol. Gen. Genet. 111: 297–299.
- Gregg, R. G., and O. Smithies 1986. Targeted modification of human chromosomal genes. Cold Spring Harbor Symp. Quant. Biol. 51: 1093–1099.
- Haber, J. E. 1995. In vivo biochemistry: physical monitoring of recombination induced by site-specific endonucleases. Bioessays 17: 609–620.
- Hasty, P., R. Ramirez-Solis, R. Krumlauf, and A. Bradley 1991. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Nature 350: 243–246.
- Hasty, P., J. Rivera-Perez, C. Chang, and A. Bradley 1991. Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells. Mol. Cell. Biol. 11: 4509–4517.
- Holliday, R. 1964. A mechanism for gene conversion in fungi. Genet. Res. 5: 282–304.
- Jasin, M. 1996. Genetic manipulation of genomes with rare-cutting endonucleases. Trends Genet. 12: 224–228.
- Jasin, M., and P. Berg 1988. Homologous integration in mammalian cells without target gene selection. Genes Dev. 2: 1353–1363.
- Kogoma, T. 1996. Recombination by replication. Cell 85: 625–627.
- Konecki, D. S., J. Brennand, J. C. Fuscoe, C. T. Caskey, and A. C. Chinault 1982. Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants. Nucleic Acids Res. 10: 6763–6775.
- Liang, F., P. J. Romanienko, D. T. Weaver, P. A. Jeggo, and M. Jasin 1996. Chromosomal double-strand break repair in Ku80-deficient cells. Proc. Natl. Acad. Sci. USA 93: 8929–8933.
- Lin, F. L., K. Sperle, and N. Sternberg 1984. Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process. Mol. Cell. Biol. 4: 1020–1034.
- Lin, F. L., K. Sperle, and N. Sternberg 1985. Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences. Proc. Natl. Acad. Sci. USA 82: 1391–1395.
- Mansour, S. L., K. R. Thomas, and M. R. Capecchi 1988. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature 336: 348–352.
- McDonald, J. P., and R. Rothstein 1994. Unrepaired heteroduplex DNA in Saccharomyces cerevisiae is decreased in RAD1 RAD52-independent recombination. Genetics 137: 393–405.
- Meselson, M. S., and C. M. Radding 1975. A general model for genetic recombination. Proc. Natl. Acad. Sci. USA 72: 358–361.
- Moynahan, M. E., and M. Jasin 1997. Loss of heterozygosity induced by a chromosomal double-strand break. Proc. Natl. Acad. Sci. USA 94: 8988–8993.
- Nag, D. K., M. A. White, and T. D. Petes 1989. Palindromic sequences in heteroduplex DNA inhibit mismatch repair in yeast. Nature 340: 318–320.
- Puchta, H., B. Dujon, and B. Hohn 1996. Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination. Proc. Natl. Acad. Sci. USA 93: 5055–5060.
- Reid, L. H., E. G. Shesely, H. S. Kim, and O. Smithies 1991. Cotransformation and gene targeting in mouse embryonic stem cells. Mol. Cell. Biol. 11: 2769–2777.
- Robertson, E., A. Bradley, M. Kuehn, and M. Evans 1986. Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector. Nature 323: 445–448.
- Ronne, H., and R. Rothstein 1988. Mitotic sectored colonies: evidence of heteroduplex DNA formation during direct repeat recombination. Proc. Natl. Acad. Sci. USA 85: 2696–2700.
- Rouet, P., F. Smih, and M. Jasin 1994. Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc. Natl. Acad. Sci. USA 91: 6064–6068.
- Rouet, P., F. Smih, and M. Jasin 1994. Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol. Cell. Biol. 14: 8096–8106.
- Sargent, R. G., M. A. Brenneman, and J. H. Wilson 1997. Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol. Cell. Biol. 17: 267–277.
- Smih, F., P. Rouet, P. J. Romanienko, and M. Jasin 1995. Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells. Nucleic Acids Res. 23: 5012–5019.
- Smith, A. J., and P. Berg 1984. Homologous recombination between defective neo genes in mouse 3T6 cells. Cold Spring Harbor Symp. Quant. Biol. 49: 171–181.
- Smithies, O., M. A. Koralewski, K. Y. Song, and R. S. Kucherlapati 1984. Homologous recombination with DNA introduced into mammalian cells. Cold Spring Harbor Symp. Quant. Biol. 49: 161–170.
- Szostak, J. W., T. L. Orr-Weaver, R. J. Rothstein, and F. W. Stahl 1983. The double-strand-break repair model for recombination. Cell 33: 25–35.
- Taghian, D. G., and J. A. Nickoloff 1997. Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells. Mol. Cell. Biol. 17: 6386–6393.
- Thomas, K. R., and M. R. Capecchi 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51: 503–512.
- Thomas, K. R., K. R. Folger, and M. R. Capecchi 1986. High frequency targeting of genes to specific sites in the mammalian genome. Cell 44: 419–428.
- Valancius, V., and O. Smithies 1991. Testing an “in-out” targeting procedure for making subtle genomic modifications in mouse embryonic stem cells. Mol. Cell. Biol. 11: 1402–1408.