A Box H/ACA Small Nucleolar RNA-Like Domain at the Human Telomerase RNA 3′ End

REFERENCES

• Ausubel F., R. Brent, R. Kingston, D. Moore, F. Seidman, J. Smith, K. Struhl 1996. Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N.Y.
   Google Scholar
• Autexier, C., and J. Greider 1996. Telomerase and cancer: revisiting the telomere hypothesis. Trends Biol. Sci. 21:387–391.
   PubMed Web of Science ®Google Scholar
• Autexier, C., R. Pruzan, W. Funk, and J. Greider 1996. Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. EMBO J. 15:5928–5935.
   PubMed Web of Science ®Google Scholar
• Avilion, A. A. 1995. Ph.D. thesis. State University of New York, Stony Brook.
   Google Scholar
• Balakin, A., L. Smith, and J. Fournier 1996. The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. Cell 86:823–834.
   PubMed Web of Science ®Google Scholar
• Beattie, T. L., W. Zhou, M. O. Robinson, and J. Harrington 1998. Reconstitution of human telomerase activity in vitro. Curr. Biol. 8:177–180.
   PubMed Web of Science ®Google Scholar
• Blasco, M. A., W. Funk, B. Villeponteau, and J. Greider 1995. Functional characterization and developmental regulation of mouse telomerase RNA. Science 269:1267–1270.
   PubMed Web of Science ®Google Scholar
• Bodnar, A. G., M. Ouellette, M. Frolkis, S. E. Holt, C.-P. Chiu, G. Morin, C. B. Harley, J. W. Shay, S. Lichtsteiner, and J. Wright 1998. Extension of life-span by introduction of telomerase into normal human cells. Science 279:349–352.
   PubMed Web of Science ®Google Scholar
• Bousquet-Antonelli, C., Y. Henry, J.-P. Gelugne, M. Caizergues-Ferrer, and J. Kiss 1997. A small nucleolar RNP protein is required for pseudouridylation of eukaryotic ribosomal RNAs. EMBO J. 16:4770–4776.
   PubMedGoogle Scholar
• Bryan, T., L. Marusic, S. Bacchetti, M. Namba, and J. Reddel 1997. The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit. Hum. Mol. Gen. 6:921–926.
   PubMed Web of Science ®Google Scholar
• Chapon, C., T. Cech, and J. Zaug 1997. Polyadenylation of telomerase RNA in budding yeast. RNA 3:1337–1351.
   PubMedGoogle Scholar
• Chen, J.-L., M. A. Blasco, and C. W. Greider. Personal communication.
   Google Scholar
• Feng, J., W. D. Funk, S. Wang, S. L. Weinrich, A. A. Avilion, C. Chiu, R. R. Adams, E. Chang, R. C. Allsopp, J. Yu, S. Le, M. West, C. B. Harley, W. H. Andrews, C. W. Greider, and J. Villeponteau 1995. The RNA component of human telomerase. Science 269:1236–1241.
   PubMed Web of Science ®Google Scholar
• Gandhi, L., and J. Collins 1998. Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates. Genes Dev. 12:721–733.
   PubMed Web of Science ®Google Scholar
• Ganot, P., M.-L. Bortolin, and J. Kiss 1997. Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs. Cell 89:799–809.
   PubMed Web of Science ®Google Scholar
• Ganot, P., M. Caizergues-Ferrer, and J. Kiss 1997. The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. Genes Dev. 11:941–956.
   PubMed Web of Science ®Google Scholar
• Girard, J.-P., H. Lehtonen, M. Caizergues-Ferrer, F. Amalric, D. Tollervey, and J. Lapeyre 1992. GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast. EMBO J. 11:673–682.
   PubMed Web of Science ®Google Scholar
• Greider, C. W. 1995. Telomerase biochemistry and regulation, p. 35–68. In E. H. Blackburn, C. W. Greider (ed.), Telomeres. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Greider, C. W. 1996. Telomere length regulation. Annu. Rev. Biochem. 66:337–365.
   Google Scholar
• Harley, C. B. 1991. Telomere loss: mitotic clock or genetic time bomb? Mutat. Res. 256:271–282.
   PubMed Web of Science ®Google Scholar
• Harley, C. B., and J. Villeponteau 1995. Telomeres and telomerase in aging and cancer. Curr. Op. Genet. Dev. 5:249–255.
   PubMedGoogle Scholar
• Harrington, L., T. McPhail, V. Mar, W. Zhou, R. Oulton, E. Program, M. B. Bass, I. Arruda, and J. Robinson 1997. A mammalian telomerase-associated protein. Science 275:973–977.
   PubMed Web of Science ®Google Scholar
• Harrington, L., W. Zhou, T. McPhail, R. Oulton, D. S. K. Yeung, V. Mar, M. B. Bass, and J. Robinson 1997. Human telomerase contains evolutionarily conserved catalytic and structural subunits. Genes Dev. 11:3109–3115.
   PubMed Web of Science ®Google Scholar
• Heiss, N. S., S. W. Knight, T. J. Vulliamy, S. M. Klauck, S. Wiemann, P. J. Mason, A. Poustka, and J. Dokal 1998. X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions. Nat. Genet. 19:32–38.
   PubMed Web of Science ®Google Scholar
• Hinkley, C., M. Blasco, W. Funk, J. Feng, B. Villeponteau, C. Greider, and J. Herr 1998. The mouse telomerase RNA 5′-end lies just upstream of the telomerase template sequence. Nucleic Acids Res. 26:532–536.
   PubMed Web of Science ®Google Scholar
• Jacobson, M. R., and J. Pederson 1998. Localization of signal recognition particle RNA in the nucleolus of mammalian cells. Proc. Natl. Acad. Sci. USA 95:7981–7986.
   PubMed Web of Science ®Google Scholar
• Kim, N. W., M. A. Piatyszek, K. R. Prowse, C. B. Harley, M. D. West, P. L. C. Ho, G. M. Coviello, W. E. Wright, S. L. Weinrich, and J. Shay 1994. Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011–2014.
   PubMed Web of Science ®Google Scholar
• Kunkel, G. R., and J. Pederson 1988. Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used. Genes Dev. 2:196–204.
   PubMed Web of Science ®Google Scholar
• Lafontaine, D. L. J., C. Bousquet-Antonelli, Y. Henry, M. Caizergues-Ferrer, and J. Tollervey 1998. The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase. Genes Dev. 12:527–537.
   PubMed Web of Science ®Google Scholar
• Marusic, L., M. Anton, A. Tidy, P. Wang, B. Villeponteau, and J. Bacchetti 1997. Reprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viability. Mol. Cell. Biol. 17:6394–6401.
   PubMed Web of Science ®Google Scholar
• McEachern, M. J., and J. Blackburn 1995. Runaway telomere elongation caused by telomerase RNA gene mutations. Nature 376:403–409.
   PubMed Web of Science ®Google Scholar
• Meier, U. T., and J. Blobel 1994. NAP57, a mammalian nucleolar protein with a putative homolog in yeast and bacteria. J. Cell Biol. 127:1505–1514.
   PubMed Web of Science ®Google Scholar
• Murnane, J. P., L. Sabatier, B. A. Marder, and J. Morgan 1994. Telomere dynamics in an immortal cell line. EMBO J. 13:4953–4962.
   PubMed Web of Science ®Google Scholar
• Nakamura, T. M., G. B. Morin, K. B. Chapman, S. L. Weinrich, W. H. Andrews, J. Lingner, C. B. Harley, and J. Cech 1997. Telomerase catalytic subunit homologs from fission yeast and human. Science 277:955–959.
   PubMed Web of Science ®Google Scholar
• Nakayama, J., M. Saito, H. Nakamura, A. Matsuura, and J. Ishikawa 1997. TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family. Cell 88:875–884.
   PubMed Web of Science ®Google Scholar
• Ni, J., A. Tien, and J. Fournier 1997. Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA. Cell 89:565–573.
   PubMed Web of Science ®Google Scholar
• Nugent, C. I., and J. Lundblad 1998. The telomerase reverse transcriptase: components and regulation. Genes Dev. 12:1073–1085.
   PubMed Web of Science ®Google Scholar
• Romero, D. P., and J. Blackburn 1991. A conserved secondary structure for telomerase RNA. Cell 67:343–353.
   PubMed Web of Science ®Google Scholar
• Schnapp, G., H.-P. Rodi, W. J. Rettig, A. Schnapp, and J. Damm 1998. One-step affinity purification protocol for human telomerase. Nucleic Acids Res. 26:3311–3313.
   PubMedGoogle Scholar
• Singer, M. S., and J. Gottschling 1994. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266:404–409.
   PubMed Web of Science ®Google Scholar
• Smith, C. M., and J. Steitz 1997. Sno storm in the nucleolus: new roles for myriad small RNPs. Cell 89:669–672.
   PubMed Web of Science ®Google Scholar
• Tyc, K., and J. Steitz 1989. U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus. EMBO J. 8:3113–3119.
   PubMed Web of Science ®Google Scholar
• Warner, J. 1979. Distribution of newly formed ribosomal proteins in HeLa cell fractions. J. Cell Biol. 80:767–772.
   PubMedGoogle Scholar
• Weinrich, S. L., R. Pruzan, L. Ma, M. Ouellette, V. M. Tesmer, S. E. Holt, A. G. Bodnar, S. Lichsteiner, N. W. Kim, J. B. Trager, R. D. Taylor, R. Carlos, W. H. Andrews, W. E. Wright, J. W. Shay, C. B. Harley, and J. Morin 1997. Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat. Genet. 17:498–502.
   PubMed Web of Science ®Google Scholar
• Zaug, A., J. Lingner, and J. Cech 1996. Method for determining RNA 3′ ends and application to human telomerase RNA. Nucleic Acids Res. 24:532–533.
   PubMedGoogle Scholar