Oxidative Stress-Induced Destruction of the Yeast C-Type Cyclin Ume3p Requires Phosphatidylinositol-Specific Phospholipase C and the 26S Proteasome

REFERENCES

• Berridge, M. J. 1993. Inositol triphosphate and calcium signaling. Nature 361:315–325.
   PubMed Web of Science ®Google Scholar
• Brewster, J. L., T. de Valoir, N. D. Dwyer, E. Winter, and J. Gustin 1993. An osmosensing signal transduction pathway in yeast. Science 259:1760–1763.
   PubMed Web of Science ®Google Scholar
• Broach, J. R. 1991. RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway. Trends Genet. 7:28–33.
   PubMedGoogle Scholar
• Buckingham, L. E., H.-T. Wang, R. T. Elder, R. M. McCarroll, M. R. Slater, and J. Esposito 1990. Nucleotide sequence and promoter analysis of SPO13, a meiosis-specific gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 87:9406–9410.
   PubMed Web of Science ®Google Scholar
• Chen, P., and J. Hochstrasser 1995. Biogenesis, structure and function of the yeast 20S proteasome. EMBO J. 14:2620–2630.
   PubMedGoogle Scholar
• Chen, P., P. Johnson, T. Sommer, S. Jentsch, and J. Hochstrasser 1993. Multiple ubiquitin-conjugated enzymes participate in the in vivo degradation of the yeast MATα2 repressor. Cell 74:357–369.
   PubMed Web of Science ®Google Scholar
• Collinson, L. P., and J. Dawes 1992. Inducibility of the response of yeast cells to peroxide stress. J. Gen. Microbiol. 138:329–335.
   PubMedGoogle Scholar
• Cooper, K. F., M. J. Mallory, J. S. Smith, and J. Strich 1997. Stress and developmental regulation of the yeast C-type cyclin UME3 (SRB11/SSN8). EMBO J. 16:4665–4675.
   PubMed Web of Science ®Google Scholar
• Cooper, K. F., and R. Strich. Functional analysis of the yeast C-type cyclin Ume3p and the RNA polymerase II holoenzyme interaction. Gene Expr., in press.
   Google Scholar
• Craig, E. A. 1993. The heat-shock response of Saccharomyces cerevisiae, p. 501–538. In E. W. Jones, J. R. Pringle, J. R. Broach (ed.), The molecular and cellular biology of the yeast Saccharomyces. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Davenport, K. R., M. Sohaskey, Y. Kamada, D. E. Levin, and J. Gustin 1995. A second osmosensing signal transduction pathway in yeast. Hypotonic shock activates the PKC1 protein kinase-regulated cell integrity pathway. J. Biol. Chem. 270:30157–30161.
   PubMedGoogle Scholar
• Deshaies, R. J., V. Chau, Kirschner. 1995. Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway. EMBO J. 14:303–312.
   PubMedGoogle Scholar
• Destruelle, M., H. Holzer, and J. Klionsky 1994. Identification and characterization of a novel yeast gene: the YGP1 gene product is a highly glycosylated secreted protein that is synthesized in response to nutrient limitation. Mol. Cell. Biol. 14:2740–2754.
   PubMed Web of Science ®Google Scholar
• Evan, G. I., G. K. Lewis, G. Ramsay, and J. Bishop 1985. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5:3610–3616.
   PubMed Web of Science ®Google Scholar
• Flick, J. S., and J. Thorner 1993. Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:5861–5876.
   PubMed Web of Science ®Google Scholar
• Galaktionov, K., and J. Beach 1991. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclin. Cell 67:1181–1194.
   PubMed Web of Science ®Google Scholar
• Galan, J., and J. Haguenauer-Tsapis 1997. Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO J. 16:5847–5854.
   PubMedGoogle Scholar
• Glotzer, M., A. W. Murray, and J. Kirschner 1991. Cyclin is degraded by the ubiquitin pathway. Nature 349:132–138.
   PubMed Web of Science ®Google Scholar
• Gustin, M. C., X.-L. Zhou, B. Martinac, and J. Kung 1988. A mechanosensitive ion channel in the yeast plasma membrane. Science 242:762–765.
   PubMed Web of Science ®Google Scholar
• Herskowitz, I. 1995. MAP kinase pathways in yeast: for mating and more. Cell 80:187–197.
   PubMed Web of Science ®Google Scholar
• Hokin, L. E. 1985. Receptors and phosphoinsitol-generated second messengers. Annu. Rev. Biochem. 54:205–235.
   PubMed Web of Science ®Google Scholar
• Jamieson, D. J. 1992. Saccharomyces cerevisiae has distinct adaptive responses to both hydrogen peroxide and menadione. J. Bacteriol. 174:6678–6681.
   PubMed Web of Science ®Google Scholar
• Jamieson, D. J., S. L. Rivers, and J. Stephen 1994. Analysis of Saccharomyces cerevisiae proteins induced by peroxide and superoxide stress. Microbiology 140:3277–3283.
   PubMed Web of Science ®Google Scholar
• Kamada, Y., U. S. Jung, J. Piotrowski, and J. Levin 1995. The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Genes Dev. 9:1559–1571.
   PubMed Web of Science ®Google Scholar
• Kornitzer, D., B. Raboy, R. G. Kulka, and J. Fink 1994. Regulated degradation of the transcription factor Gcn4. EMBO J. 13:6021–6030.
   PubMedGoogle Scholar
• Krems, B., C. Charizanis, and J. Entian 1996. The response regulator-like protein Pos9/Skn7 of Saccharomyces cerevisiae is involved in oxidative stress resistance. Curr. Genet. 29:327–334.
   PubMed Web of Science ®Google Scholar
• Lanker, S., M. H. Valdivieso, and J. Wittenberg 1996. Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation. Science 271:1597–1600.
   PubMed Web of Science ®Google Scholar
• Lee, K. S., K. Irie, Y. Gotoh, Y. Watanabe, H. Araki, E. Nishida, K. Matsumoto, and J. Levin 1993. A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Mol. Cell. Biol. 13:3067–3075.
   PubMed Web of Science ®Google Scholar
• Levin, D. E., F. O. Fields, R. Kunisawa, J. M. Bishop, and J. Thorner 1990. A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell 62:213–224.
   PubMed Web of Science ®Google Scholar
• Longtine, M. S., A. R. McKenzie, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. Pringle 1998. Additional modules of versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953–961.
   PubMed Web of Science ®Google Scholar
• Mager, W. H., and J. De Kruijff 1995. Stress-induced transcriptional activation. Microbiol. Rev. 59:506–531.
   PubMedGoogle Scholar
• Maniatis, T., E. F. Fritsch, J. Sambrook 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Moradas-Ferreira, P., V. Costa, P. Piper, and J. Mager 1996. The molecular defences against reactive oxygen species in yeast. Mol. Microbiol. 19:651–658.
   PubMed Web of Science ®Google Scholar
• Morimoto, R. I., K. D. Sarge, and J. Abravaya 1992. Transcriptional regulation of heat shock genes. J. Biol. Chem. 267:21987–21990.
   PubMed Web of Science ®Google Scholar
• Papa, F., and J. Hochstrasser 1993. The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature 25:313–319.
   Google Scholar
• Paulovich, A. G., and J. Hartwell 1995. A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell 82:841–847.
   PubMed Web of Science ®Google Scholar
• Payne, W. E., and J. Fitzgerald-Hayes 1993. A mutation in PLC1, a candidate phosphoinositide-specific phospholipase C gene from Saccharomyces cerevisiae, causes aberrant mitotic chromosome segregation. Mol. Cell. Biol. 13:4351–4364.
   PubMedGoogle Scholar
• Pines, J. 1993. Cyclins and cyclin-dependent kinases: take your partners. Trends Biochem. Sci. 18:195–197.
   PubMed Web of Science ®Google Scholar
• Piper, P. W., K. Talreja, B. Panaretou, P. Moradas-Ferreira, K. Byrne, U. M. Praekelt, P. Meacock, M. Recnacq, and J. Boucerie 1994. Induction of major heat-shock proteins of Saccharomyces cerevisiae, including plasma membrane Hsp30, by ethanol levels above a critical threshold. Microbiology 140:3031–3038.
   PubMed Web of Science ®Google Scholar
• Ramos, P. C., J. Hockendorff, E. S. Johnson, A. Varshavsky, and J. Dohmen 1998. Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92:489–499.
   PubMed Web of Science ®Google Scholar
• Salama, S. R., K. B. Hendricks, and J. Thorner 1994. G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover. Mol. Cell. Biol. 14:7953–7966.
   PubMedGoogle Scholar
• Sanchez, Y., J. Taulien, K. A. Borkovich, and J. Lindquist 1992. Hsp104 is required for tolerance to many forms of stress. EMBO J. 11:2357–2364.
   PubMed Web of Science ®Google Scholar
• Santoro, N., D. J. Thiele 1997. Yeast stress responses, p. 171–203. In S. Hohmann, W. H. Mager (ed.), Molecular biology intelligence unit. R. G. Landes Co., Austin, Tex.
   Google Scholar
• Schauber, C., L. Chen, P. Tongaonkar, I. Vega, D. Lambertson, W. Potts, and J. Madura 1998. Rad23 links DNA repair to the ubiquitin/proteasome pathway. Nature 391:715–718.
   PubMed Web of Science ®Google Scholar
• Slater, M. R., and J. Craig 1987. Transcriptional regulation of an hsp70 heat shock gene in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 7:1906–1916.
   PubMedGoogle Scholar
• Stephen, D., S. Rivers, and J. Jamieson 1995. The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae. Mol. Microbiol. 16:415–423.
   PubMed Web of Science ®Google Scholar
• Strich, R., M. R. Slater, and J. Esposito 1989. Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast. Proc. Natl. Acad. Sci. USA 86:10018–10022.
   PubMedGoogle Scholar
• Strich, R., M. Woontner, and J. Scott 1986. Mutations in ARS1 increase the rate of simple loss of plasmids in Saccharomyces cerevisiae. Yeast 2:169–178.
   PubMedGoogle Scholar
• Surosky, R. T., and J. Esposito 1992. Early meiotic transcripts are highly unstable in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:3948–3958.
   PubMedGoogle Scholar
• Tatchell, K., L. C. Robinson, and J. Breitenbach 1985. RAS2 of Saccharomyces cerevisiae is required for glyconeogenic growth and proper response to nutrient limitation. Proc. Natl. Acad. Sci. USA 82:3785–3789.
   PubMedGoogle Scholar
• Tyers, M., G. Tokiwa, R. Nash, and J. Futcher 1992. The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. EMBO J. 11:1773–1784.
   PubMedGoogle Scholar
• Varela, J. C. S., U. M. Praekelt, P. A. Meacock, R. J. Planta, and J. Mager 1995. The Saccharomyces cerevisiae HSP12 gene is activated by the high-osmolarity glycerol pathway and negatively regulated by protein kinase A. Mol. Cell. Biol. 15:6232–6245.
   PubMedGoogle Scholar
• Wilson, B. A., M. Khalil, R. Tamonoi, and J. Cannon 1993. New activated RAS2 mutations identified in Saccharomyces cerevisiae. Oncogene 8:3441–3445.
   PubMedGoogle Scholar
• Woodford, D. V., H. H. Parish, and J. Moradas-Ferreira 1995. Hydrogen peroxide induces DNA damage in Saccharomyces cerevisiae. Yeast 11:149.
   Google Scholar
• Yaglom, J., M. H. K. Linskens, S. Sadis, D. M. Rubin, B. Futcher, and J. Finley 1995. p34Cdc28-mediated control of Cln3 cyclin degradation. Mol. Cell. Biol. 15:731–741.
   PubMedGoogle Scholar
• Yang, J.-M., K.-V. Chin, and J. Hait 1995. Involvement of phospholipase c in heat-shock-induced phosphorylation of P-glycoprotein in multidrug resistant human breast cancer cells. Biochem. Biophys. Res. Commun. 210:21–30.
   PubMedGoogle Scholar
• Zheng, X. F., and J. Ruderman 1993. Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25. cell 75:155–164.
   PubMedGoogle Scholar