Yeast Mutants Affecting Possible Quality Control of Plasma Membrane Proteins

REFERENCES

• Anderson, M. T., I. M. Tjioe, M. C. Lorincz, D. R. Parks, L. A. Herzenberg, G. P. Nolan, and J. Herzenberg 1996. Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins. Proc. Natl. Acad. Sci. USA 93:8508–8511.
   PubMedGoogle Scholar
• Antebi, A., and J. Fink 1992. The yeast Ca2+ ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution. Mol. Biol. Cell 3:633–654.
   PubMed Web of Science ®Google Scholar
• Babst, M., and S. Emr. Personal communication.
   Google Scholar
• Babst, M., B. Wendland, E. J. Estepa, and J. Emr 1998. The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J. 17:2982–2993.
   PubMed Web of Science ®Google Scholar
• Biwersi, J., N. Emans, and J. Verkman 1996. Cystic fibrosis transmembrane conductance regulator activation stimulates endosome fusion in vivo. Proc. Natl. Acad. Sci. USA 93:12484–12489.
   PubMedGoogle Scholar
• Chang, A., and J. Fink 1995. Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole. J. Cell Biol. 128:39–49.
   PubMedGoogle Scholar
• Cooper, A. A., and J. Stevens 1996. Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. J. Cell Biol. 133:529–541.
   PubMedGoogle Scholar
• Davis, N. G., J. L. Horecka, G. F. Sprague Jr.. 1993. cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J. Cell Biol. 122:53–65.
   PubMed Web of Science ®Google Scholar
• Futter, C. E., A. Pearse, L. J. Hewlett, and J. Hopkins 1996. Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes. J. Cell Biol. 132:1011–1023.
   PubMed Web of Science ®Google Scholar
• Gaxiola, R. A., D. S. Yuan, R. D. Klausner, and J. Fink 1998. The yeast CLC chloride channel functions in cation homeostasis. Proc. Natl. Acad. Sci. USA 95:4046–4050.
   PubMed Web of Science ®Google Scholar
• Gerdes, H.-H., and J. Kaether 1996. Green fluorescent protein: applications in cell biology. FEBS Lett. 389:44–47.
   PubMed Web of Science ®Google Scholar
• Greene, J. R., N. H. Brown, B. J. DiDomenico, J. Kaplan, and J. Eide 1993. The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein; mutations in which have effects on respiration and iron-limited growth. Mol. Gen. Genet. 241:542–553.
   PubMedGoogle Scholar
• Hartwell, L. H. 1980. Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone. J. Cell Biol. 85:811–822.
   PubMed Web of Science ®Google Scholar
• Hechenberger, M., B. Schwappach, W. N. Fischer, W. B. Frommer, T. J. Jentsch, and J. Steinmeyer 1996. A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption. J. Biol. Chem. 271:33632–33638.
   PubMed Web of Science ®Google Scholar
• Hicke, L., and J. Riezman 1996. Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis. Cell 84:277–287.
   PubMed Web of Science ®Google Scholar
• Hirschman, J., G. DeZutter, W. Simonds, and J. Jenness 1997. The Gβγ complex of the yeast pheromone response pathway: subcellular fractionation and protein-protein interaction. J. Biol. Chem. 272:240–248.
   PubMedGoogle Scholar
• Hong, E., A. R. Davidson, and J. Kaiser 1996. A pathway for targeting soluble misfolded proteins to the yeast vacuole. J. Cell Biol. 135:623–633.
   PubMed Web of Science ®Google Scholar
• Hsu, V. W., L. C. Yuan, J. G. Nuchtern, J. Lippincott-Schwartz, G. J. Hammerling, and J. Klausner 1991. A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules. Nature 352:441–444.
   PubMed Web of Science ®Google Scholar
• Hwa, J., P. Garriga, X. Liu, and J. Khorana 1997. Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled. Proc. Natl. Acad. Sci. USA 94:10571–10576.
   PubMed Web of Science ®Google Scholar
• Jenness, D. D., B. S. Goldman, and J. Hartwell 1987. Saccharomyces cerevisiae mutants unresponsive to α-factor pheromone: α-factor binding and extragenic suppression. Mol. Cell. Biol. 7:1311–1319.
   PubMedGoogle Scholar
• Jenness, D. D., Y. Li, C. Tipper, and J. Spatrick 1997. Elimination of defective α-factor pheromone receptors. Mol. Cell. Biol. 17:6236–6245.
   PubMedGoogle Scholar
• Jenness, D. D., and J. Spatrick 1986. Down regulation of the α-factor pheromone receptor in S. cerevisiae. Cell 46:345–353.
   PubMedGoogle Scholar
• Jones, E. W., G. C. Webb, and J. Hiller 1997. Biogenesis and function of the yeast vacuole The molecular and cellular biology of the yeast Saccharomyces In J. R. Pringle, J. R. Broach, E. W. Jones (ed.), III:363–470 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• Katz, M. E., J. Ferguson, and J. Reed 1987. Temperature-sensitive lethal pseudorevertants of ste mutations in Saccharomyces cerevisiae. Genetics 115:627–636.
   PubMedGoogle Scholar
• Kaushal, S., and J. Khorana 1994. Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. Biochemistry 33:6121–6128.
   PubMed Web of Science ®Google Scholar
• Konopka, J. B., D. D. Jenness, and J. Hartwell 1988. The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone. Cell 54:609–620.
   PubMedGoogle Scholar
• Kopito, R. R. 1997. ER quality control: the cytoplasmic connection. Cell 88:427–430.
   PubMed Web of Science ®Google Scholar
• Kubler, E., and J. Riezman 1993. Actin and fimbrin are required for the internalization step of endocytosis. EMBO J. 12:2855–2862.
   PubMed Web of Science ®Google Scholar
• Li, L., and J. Cohen 1996. Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells. Cell 85:319–329.
   PubMed Web of Science ®Google Scholar
• Luo, W., and J. Chang 1997. Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J. Cell Biol. 138:731–746.
   PubMed Web of Science ®Google Scholar
• Lupas, A. 1996. Predictions and analysis of coiled-coil structures. Methods Enzymol. 266:513–525.
   PubMed Web of Science ®Google Scholar
• Marcusson, E. G., B. F. Horazdovsky, J. L. Cereghino, E. Gharakhanian, and J. Emr 1994. The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell 77:579–586.
   PubMed Web of Science ®Google Scholar
• Minami, Y., A. M. Weissman, L. E. Samelson, and J. Klausner 1987. Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor. Proc. Natl. Acad. Sci. USA 84:2688–2692.
   PubMed Web of Science ®Google Scholar
• Newlon, C. S., L. R. Lipchitz, I. Collins, A. Deshpande, R. J. Devenish, R. P. Green, H. L. Klein, T. G. Palzkill, R. B. Ren, S. Synn, and J. Woody 1991. Analysis of a circular derivative of Saccharomyces cerevisiae chromosome III: a physical map and identification and localization of ARS elements. Genetics 129:343–357.
   PubMedGoogle Scholar
• Oliver, S. G., Q. J. van der Aart, M. L. Agostoni-Carbone, M. Aigle, L. Alberghina, D. Alexandraki, G. Antoine, R. Anwar, J. P. Ballesta, P. Benit, G. Berben, E. Bergantino, N. Biteau, P. A. Bolle, M. Bolotinfukuhara, A. Brown, A. J. P. Brown, J. M. Buhler, C. Carcano, G. Carignani, H. Cederberg, R. Chanet, R. Contreras, M. Crouzet, B. Daignanfornier, E. Defoor, M. Delgado, J. Demolder, C. Doira, E. Dubois, B. Dujon, and J. Dusterhoft 1992. The complete DNA sequence of yeast chromosome III. Nature 357:38–46.
   PubMed Web of Science ®Google Scholar
• Ormö, M., A. B. Cubitt, K. Kallio, L. A. Gross, R. Y. Tsien, and J. Remington 1996. Crystal structure of the Aequorea victoria green fluorescent protein. Science 273:1392–1395.
   PubMed Web of Science ®Google Scholar
• Parlati, F., M. Dominguez, J. J. M. Bergeron, and J. Thomas 1995. Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and calreticulin and functions as a constituent of the ER quality control apparatus. J. Biol. Chem. 270:244–253.
   PubMedGoogle Scholar
• Piper, R. C., A. A. Cooper, H. Yang, and J. Stevens 1995. VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J. Cell Biol. 131:603–617.
   PubMedGoogle Scholar
• Raymond, C. K., I. Howaldstevenson, C. A. Vater, and J. Stevens 1992. Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class-E vps mutants. Mol. Biol. Cell 3:1389–1402.
   PubMed Web of Science ®Google Scholar
• Raymond, C. K., P. J. O’Hara, G. Eichinger, J. H. Rothman, and J. Stevens 1990. Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J. Cell Biol. 111:877–892.
   PubMedGoogle Scholar
• Rieder, S. E., L. M. Banta, K. Kohrer, J. M. McCaffery, and J. Emr 1996. Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol. Biol. Cell 7:985–999.
   PubMedGoogle Scholar
• Rieder, S. E., and J. Emr 1997. A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. Mol. Biol. Cell 8:2307–2327.
   PubMed Web of Science ®Google Scholar
• Rose, M. D., P. Novick, J. H. Thomas, D. Botstein, and J. Fink 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60:237–243.
   PubMed Web of Science ®Google Scholar
• Roth, A. F., and J. Davis 1996. Ubiquitination of the yeast a-factor receptor. J. Cell Biol. 134:661–674.
   PubMedGoogle Scholar
• Rybak, S. L., F. Lanni, and J. Murphy 1997. Theoretical considerations on the role of membrane potential in the regulation of endosomal pH. Biophys. J. 73:674–687.
   PubMed Web of Science ®Google Scholar
• Schandel, K. A., and J. Jenness 1994. Direct evidence for ligand-induced internalization of the yeast α-factor pheromone receptor. Mol. Cell. Biol. 14:7245–7255.
   PubMed Web of Science ®Google Scholar
• Singerkruger, B., H. Stenmark, A. Dusterhoft, P. Philippsen, J. S. Yoo, D. Gallwitz, and J. Zerial 1994. Role of three rab5-like Gtpases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast. J. Cell Biol. 125:283–298.
   PubMedGoogle Scholar
• Singerkruger, B., H. Stenmark, and J. Zerial 1995. Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway. J. Cell Sci. 108:3509–3521.
   PubMedGoogle Scholar
• Sprague, G. F. Jr., and J. Herskowitz 1981. Control of yeast cell type by the mating type locus. I. Identification and control of expression of the a-specific gene BAR1. J. Mol. Biol. 153:305–321.
   PubMedGoogle Scholar
• Symington, L. S., A. Brown, S. G. Oliver, P. Greenwell, and J. Petes 1991. Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. Genetics 128:717–727.
   PubMedGoogle Scholar
• Takeshige, K., M. Baba, S. Tsuboi, T. Noda, and J. Ohsumi 1992. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119:301–311.
   PubMed Web of Science ®Google Scholar
• Trowbridge, I. S., J. F. Collawn, and J. Hopkins 1993. Signal-dependent membrane protein trafficking in the endocytic pathway. Annu. Rev. Cell Biol. 9:129–161.
   PubMedGoogle Scholar
• Van Dyke, R. W. 1988. Proton pump-generated electrochemical gradients in rat liver multivesicular bodies. Quantitation and effects of chloride. J. Biol. Chem. 263:2603–2611.
   PubMedGoogle Scholar
• Vida, T. A., and J. Emr 1995. A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J. Cell Biol. 128:779–792.
   PubMed Web of Science ®Google Scholar
• Vida, T. A., G. Huyer, and J. Emr 1993. Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment. J. Cell Biol. 121:1245–1256.
   PubMedGoogle Scholar
• Vieira, A. V., C. Lamaze, and J. Schmid 1996. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274:2086–2089.
   PubMed Web of Science ®Google Scholar
• Wilcox, C. A., K. Redding, R. Wright, and J. Fuller 1992. Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole. Mol. Biol. Cell 3:1353–1371.
   PubMedGoogle Scholar
• Wurmser, A. E., and J. Emr 1998. Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities. EMBO J. 17:4930–4942.
   PubMedGoogle Scholar
• Xie, W., L. Li, and J. Cohen 1998. Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency. Proc. Natl. Acad. Sci. USA 95:1595–1600.
   PubMed Web of Science ®Google Scholar
• Zhong, Q., C. F. Chen, Y. Chen, P. L. Chen, and J. Lee 1997. Identification of cellular TSG101 protein in multiple human breast cancer cell lines. Cancer Res. 57:4225–4228.
   PubMed Web of Science ®Google Scholar