58
Views
415
CrossRef citations to date
0
Altmetric
Cell Growth and Development

ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose

, , , , , , , , , & show all
Pages 3760-3768 | Received 21 Sep 1998, Accepted 28 Jan 1999, Published online: 28 Mar 2023

REFERENCES

  • Berry, M. N., and J. Friend 1969. High yield preparation of isolated rat liver parenchymal cells. J. Cell Biol. 43:506–520.
  • Brown, M. S., and J. Goldstein 1997. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89:331–340.
  • Chomczynski, P., and J. Sacchi 1987. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-choroform extraction. Anal. Biochem. 162:156–159.
  • Coupé, C., D. Perdereau, P. Ferré, Y. Hitier, M. Narkewicz, and J. Girard 1990. Lipogenic enzyme activities and mRNA in rat adipose tissue at weaning. Am. J. Physiol. 258:E126–E133.
  • Doiron, B., M. H. Cuif, A. Kahn, and J. Diaz-Guerra 1994. Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter. J. Biol. Chem. 269:10213–10216.
  • Dugail, I., A. Quignard-Boulangé, X. Le Liepvre, B. Ardouin, and J. Lavau 1992. Gene expression of lipid storage-related enzymes in adipose tissue of the genetically obese Zucker rat. Biochem. J. 281:607–611.
  • Emtage, P. C. R., Y. Wan, J. L. Bramson, F. L. Graham, and J. Gauldie 1998. A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model. J. Immunol. 160:2531–2538.
  • Foretz, M., D. Carling, G. Guichard, P. Ferré, and J. Foufelle 1998. AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes. J. Biol. Chem. 273:14767–14771.
  • Foufelle, F., B. Gouhot, J. P. Pégorier, D. Perdereau, J. Girard, and J. Ferré 1992. Glucose stimulation of lipogenic enzyme gene expression in cultured white adipose tissue. J. Biol. Chem. 267:20543–20546.
  • Girard, J., P. Ferré, and J. Foufelle 1997. Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes. Annu. Rev. Nutr. 17:325–352.
  • Green, H., and J. Kehinde 1975. An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 5:19–26.
  • Gregor, P. D., M. Sawadogo, and J. Roeder 1990. The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev. 4:1730–1740.
  • Horton, J. D., Y. Bashmakov, I. Shimomura, and J. Shimano 1998. Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc. Natl. Acad. Sci. USA 95:5987–5992.
  • Horton, J. D., I. Shimomura, M. Brown, R. Hammer, J. L. Goldstein, and J. Shimano 1998. Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element binding protein 2. J. Clin. Investig. 101:2331–2339.
  • Kaytor, E. N., H. M. Shih, and J. Towle 1997. Carbohydrate regulation of hepatic gene expression: evidence against a role for the upstream stimulatory factor. J. Biol. Chem. 272:7525–7531.
  • Kim, J. B., P. Sarraf, M. Wright, K. M. Yao, E. Mueller, G. Solanes, B. B. Lowell, and J. Spiegelman 1998. Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J. Clin. Investig. 101:1–9.
  • Kim, J. B., and J. Spiegelman 1996. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev. 10:1096–1107.
  • Kim, J. B., G. D. Spotts, Y. D. Halvorsen, H. M. Shih, T. Ellenberger, H. C. Towle, and J. Spiegelman 1995. Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol. Cell. Biol. 15:2582–2588.
  • Lafont, A., G. Loirand, P. Pacaud, F. Vilde, P. Lemarchand, and J. Escande 1997. Vasomotor dysfunction early after exposure of normal rabbit arteries to an adenoviral vector. Hum. Gene Ther. 8:1033–1040.
  • Lefrançois-Martinez, A. M., M. J. Diaz-Guerra, V. Vallet, A. Kahn, and J. Antoine 1994. Glucose-dependent regulation of the l-pyruvate kinase gene in a hepatoma cell line is independent of insulin and cyclic AMP. FASEB J. 8:89–96.
  • Lefrancois-Martinez, A. M., A. Martinez, B. Antoine, M. Raymondjean, and J. Kahn 1995. Upstream stimulatory factor proteins are major components of the glucose response complex of the L-type pyruvate kinase gene promoter. J. Biol. Chem. 270:2640–2643.
  • Mariash, C. N., S. Seelig, H. L. Schwartz, and J. Oppenheimer 1986. Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction. J. Biol. Chem. 261:9583–9586.
  • Mourrieras, F., F. Foufelle, M. Foretz, J. Morin, S. Bouché, and J. Ferré 1997. Induction of fatty acid synthase and S14 gene expression by glucose, xylitol and dihydroxyacetone in cultured rat hepatocytes is closely correlated with glucose 6-phosphate concentrations. Biochem. J. 323:345–349.
  • Moustaïd, N., R. S. Beyer, and J. Sul 1994. Identification of an insulin response element in the fatty acid synthase promoter. J. Biol. Chem. 269:5629–5634.
  • Oualikene, O., P. Gonin, and J. Eloit 1995. Lack of evidence of phenotypic complementation of E1A/E1B-deleted adenovirus type 5 upon superinfection by wild-type virus in the cotton rat. J. Virol. 69:6518–6524.
  • Prip-Buus, C., D. Perdereau, F. Foufelle, J. Maury, P. Ferré, and J. Girard 1995. Induction of fatty acid synthase gene expression by glucose in primary culture of rat hepatocytes. Eur. J. Biochem. 230:309–315.
  • Sasaki, K., T. P. Cripe, S. R. Koch, T. L. Andreone, D. D. Petersen, E. G. Beale, and J. Granner 1984. Multihormonal regulation of PEPCK gene transcription. The dominant role of insulin. J. Biol. Chem. 259:15242–15251.
  • Sheng, Z., H. Otani, M. S. Brown, and J. Goldstein 1995. Independent regulation of sterol regulatory element binding proteins 1 and 2 in hamster liver. Proc. Natl. Acad. Sci. USA 92:935–938.
  • Shimano, H., J. D. Horton, I. Shimomura, R. E. Hammer, M. S. Brown, and J. Goldstein 1997. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J. Clin. Investig. 99:846–854.
  • Shimano, H., I. Shimomura, R. E. Hammer, J. Herz, J. L. Goldstein, M. S. Brown, and J. Horton 1997. Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. J. Clin. Investig. 100:2115–2124.
  • Shimomura, I., H. Shimano, J. D. Horton, J. L. Goldstein, and J. Brown 1997. Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J. Clin. Investig. 99:838–845.
  • Tontonoz, P., J. B. Kim, R. A. Graves, and J. Spiegelman 1993. ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol. Cell. Biol. 13:4753–4759.
  • Towle, H. C., E. N. Kaytor, and J. Shih 1997. Regulation of the expression of lipogenic enzyme genes by carbohydrate. Annu. Rev. Nutr. 17:405–433.
  • Wang, X., R. Sato, M. S. Brown, X. Hua, and J. Goldstein 1994. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell 77:53–62.
  • Yokoyama, C., X. Wang, M. R. Briggs, A. Admon, J. Wu, X. Hua, J. L. Goldstein, and J. Brown 1993. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell 75:187–197.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.