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DNA Dynamics and Chromosome Structure

Large T-Antigen Double Hexamers Imaged at the Simian Virus 40 Origin of Replication

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Pages 34-41 | Received 14 Jun 1999, Accepted 28 Sep 1999, Published online: 28 Mar 2023

REFERENCES

  • Arthur, A. K., Höss, A., and Fanning, E.. 1998. Expression of simian virus 40 T antigen in Escherichia coli: localization of T-antigen origin DNA-binding domain to within 129 amino acids. J. Virol. 62:2204–2208
  • Borowiec, J. A., and Hurwitz, J.. 1998. ATP stimulates the binding of simian virus 40 (SV40) large tumour antigen to the SV40 origin of replication. Proc. Natl. Acad. Sci. USA 85:64–68
  • Borowiec, J. A., Dean, F. B., Bullock, P. A., and Hurwitz, J.. 1990. Binding and unwinding. How T antigen engages the SV40 origin of DNA replication. Cell 60:181–184
  • Braithwaite, A., Stürzbeches, H., Addison, C., Palmer, C., Rudge, K., and Jenkins, J. R.. 1987. Mouse p53 inhibits SV40 origin-dependent DNA replication. Nature 329:458–460
  • Dean, F. B., Dodson, M., Echols, H., and Hurwitz, J.. 1987. ATP-dependent formation of a specialized nucleoprotein structure by simian virus 40 (SV40) large tumor antigen at the replication origin. Proc. Natl. Acad. Sci. USA 84:8981–8985
  • Dean, F. B., and Hurwitz, J.. 1991. Simian virus 40 large T antigen untwist DNA at the origin of DNA replication. J. Biol. Chem. 266:5062–5071
  • Dean, F. B., Borowiec, J. A., Eki, T., and Hurwitz, J.. 1992. The simian virus T antigen double hexamer assembles around the DNA at replication origin. J. Biol. Chem. 267:14129–14137
  • Deb, S., De Lucía, A. L., Banr, C.-P., Koff, A., and Tegtmeyer, P.. 1986. Domain structure of the simian virus 40 core origin of replication. Mol. Cell. Biol. 6:1663–1670
  • De Caprio, J. A., Ludlow, J. W., Figge, J., Shew, J. Y., Huang, C. M., Lee, W. H., Marsillo, E., Pancha, E., and Livingston, D. M.. 1988. SV40 large tumour antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54:275–283
  • De Lucia, A. L., Deb, S., Partin, K., and Tegtmeyer, P.. 1986. Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences. J. Virol. 57:138–144
  • Dodson, M., Dean, F. B., Bullock, P., Echols, H., and Hurwitz, J.. 1987. Unwinding of duplex DNA from the SV40 origin of replication by T antigen. Science 238:964–967
  • Fanning, E., and Knippers, R.. 1992. Structure and function of simian virus 40 large tumour antigen. Annu. Rev. Biochem. 61:55–85
  • Gurney, E. G., Harrison, R. O., and Fenno, J.. 1980. Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct subclasses of large T antigens and for similarities among nonviral T antigens. J. Virol. 34:752–763
  • Gurney, E. G., Tamowsky, D., and Deppert, W.. 1986. Antigenic binding sites of monoclonal antibodies specific for simian virus large T antigen. J. Virol. 57:1168–1172
  • Joo, W. S., Luo, X., Dennis, D., Kim, H. Y., Rainey, G. J., Jones, C., Sreekumar, K. R., and Bullock, P. A.. 1997. Purification of the simian virus 40 (SV40) T antigen DNA-binding domain and characterization of its interactions with the SV40 origin. J. Virol. 71:3972–3985
  • Joo, W. S., Kim, H. Y., Purviance, J. D., Sreekumar, K. R., and Bullock, P. A.. 1998. Assembly of T-antigen double hexamers on the simian virus 40 core origin requires only a subset of the available binding sites. Mol. Cell. Biol. 18:2677–2687
  • Kohonen, T.. 1990. The self-organizing map. Proc. IEEE 78:1464–1480
  • Lewine, A. J.. 1992. The DNA tumour viruses Viruses. 87–111 Scientific American Library, New York, N.Y
  • Li, J. J., and Kelly, T. J.. 1985. Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication. Mol. Cell. Biol. 11:2108–2115
  • Li, J. J., Peden, K. W. C., Dixon, R. A. F., and Kelly, T.. 1986. Functional organization of the simian virus 40 origin of DNA replication. Mol. Cell. Biol. 6:1117–1128
  • Luo, X., Sanford, D. G., Bullock, P. A., and Bachovchin, W. W.. 1996. Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat. Struct. Biol. 3:1034–1039
  • Marabini, R., and Carazo, J. M.. 1994. Pattern recognition and classification of images of biological macromolecules using artificial neural networks. Biophys. J. 66:1804–1814
  • Marabini, R., Masegosa, I. M., San Martín, M. C., Marco, S., Fernández, J. J., de la Fraga, L. G., Vaquerizo, C., and Carazo, J. M.. 1996. XMIPP: an image processing package for electron microscopy. J. Struct. Biol. 116:237–240
  • Marco, S., Chagoyen, M., de la Fraga, L. G., Carazo, J. M., and Carrascosa, J. L.. 1996. A variant to the random approximation of the reference-free alignment algorithm. Ultramicroscopy 66:5–10
  • Mastrangelo, I. A., Hough, P. V. C., Wall, J. S., Dodson, M., Dean, F. B., and Hurwitz, J.. 1989. ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication. Nature 338:658–662
  • Mastrangelo, I. A., Bezanilla, M., Hansma, P. K., Hough, P. V. C., and Hansma, H. G.. 1994. Structures of large T antigen at the origin of SV40 DNA replication by atomic force microscopy. Biophys. J. 66:293–298
  • Mole, S. E., Gannon, J. V., Ford, M. J., and Lane, D. P.. 1987. Structure and function of large T antigen. Philos. Trans. R. Soc. Lond. Ser. B 317:455–469
  • Penzeck, P., Radermacher, M., and Frank, J.. 1992. Three-dimensional reconstructions of single particle embedded in ice. Ultramicroscopy 40:33–53
  • San Martín, M. C., Gruss, C., and Carazo, J. M.. 1997. Six molecules of SV40 large T antigen assemble in a propeller-shaped particle around a channel. J. Mol. Biol. 268:15–20
  • Simanis, V., and Lane, D. P.. 1985. An immunoaffinity purification procedure for SV40 large tumour antigen. Virology 144:88–100
  • Tsurimoto, T., Melendy, T., and Stillman, B.. 1990. Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. Nature 346:534–539
  • Unser, M., Trus, B., and Steven, A. C.. 1987. A new resolution criterion based on spectral signal-to-noise ratios. Ultramicroscopy 23:39–52
  • Weisshart, K., Taneja, P., Jenne, A., Herbig, U., Simmons, D. T., and Fanning, E.. 1999. Two regions of simian virus 40 T antigen determine cooperativity of double-hexamer assembly on the viral origin of DNA replication and promote hexamer interactions during bidirectional origin DNA unwinding. J. Virol. 73:2201–2211
  • Wessel, R., Schweizer, J., and Stahl, H.. 1992. Simian virus 40 T-antigen DNA helicase is a hexamer which forms a binary complex during bidirectional unwinding from the viral origin of DNA replication. J. Virol. 66:804–815

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