Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

REFERENCES

• Alaoui-Jamali, M., Loubaba, B. B., Robyn, S., Tapiero, H., and Batist, G.. 1994. Effect of DNA-repair-enzyme modulators on cytotoxicity of l-phenylalanine mustard and cis-diamminedichloroplatinum (II) in mammary carcinoma cells resistant to alkylating drugs. Cancer Chemother. Pharmacol. 34:153–158
   PubMedGoogle Scholar
• Averbeck, D., Dardalhon, M., Magana-Schwencke, N., Meira, L. B., Meniel, V., Boiteux, S., and Sage, E.. 1992. New aspects of the repair and genotoxicity of psoralen photoinduced lesions in DNA. J. Photochem. Photobiol. B 14:47–63
   PubMedGoogle Scholar
• Bishop, D. K., Ear, U., Bhattacharyya, A., Calderone, C., Beckett, M., Weichselbaum, R. R., and Shinohara, A.. 1998. Xrcc3 is required for assembly of Rad51 complexes in vivo. J. Biol. Chem. 273:21482–21488
   PubMed Web of Science ®Google Scholar
• Bockmuhl, U., Petersen, S., Schmidt, S., Wolf, G., Jahnke, V., Dietel, M., and Petersen, I.. 1997. Patterns of chromosomal alterations in metastasizing and nonmetastasizing primary head and neck carcinomas. Cancer Res. 57:5213–5216
   PubMed Web of Science ®Google Scholar
• Bramson, J., McQuillan, A., Aubin, R., Alaoui-Jamali, M., Batist, G., Christodoulopoulos, G., and Panasci, L. C.. 1995. Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance. Mutat. Res. 336:269–278
   PubMed Web of Science ®Google Scholar
• Brendel, M., and Ruhland, A.. 1984. Relationships between functionality and genetic toxicology of selected DNA-damaging agents. Mutat. Res. 133:51–85
   PubMed Web of Science ®Google Scholar
• Buchwald, M., and Moustacchi, E.. 1998. Is Fanconi anemia caused by a defect in the processing of DNA damage? Mutat. Res. 408:75–90
   PubMedGoogle Scholar
• Carreau, M., Gan, O. I., Liu, L., Doedens, M., McKerlie, C., Dick, J. E., and Buchwald, M.. 1998. Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage. Blood 91:2737–2744
   PubMed Web of Science ®Google Scholar
• Cassier-Chauvat, C., and Moustacchi, E.. 1988. Allelism between pso1-1 and rev3-1 mutants and between pso2-1 and snm1 mutants in Saccharomyces cerevisiae. Curr. Genet. 13:37–40
   PubMedGoogle Scholar
• Chen, M., Tomkins, D. J., Auerbach, W., McKerlie, C., Youssoufian, H., Liu, L., Gan, O., Carreau, M., Auerbach, A., Groves, T., Guidos, C. J., Freedman, M. H., Cross, J., Percy, D. H., Dick, J. E., Joyner, A. L., and Buchwald, M.. 1996. Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nat. Genet. 12:448–451
   PubMedGoogle Scholar
• Collins, A. R.. 1993. Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics. Mutat. Res. 293:99–118
   PubMed Web of Science ®Google Scholar
• Cui, X., Brenneman, M., Meyne, J., Oshimura, M., Goodwin, E. H., and Chen, D. J.. 1999. The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells. Mutat. Res. 434:75–88
   PubMed Web of Science ®Google Scholar
• Dardalhon, M., and Averbeck, D.. 1995. Pulsed-field gel electrophoresis analysis of the repair of psoralen plus UVA induced DNA photoadducts in Saccharomyces cerevisiae. Mutat. Res. 336:49–60
   PubMedGoogle Scholar
• de Boer, J., and Hoeijmakers, J. H.. 1999. Cancer from the outside, aging from the inside: mouse models to study the consequences of defective nucleotide excision repair. Biochimie 81:127–137
   PubMedGoogle Scholar
• de Winter, J. P., Waisfisz, Q., Rooimans, M. A., van Berkel, C. G., Bosnoyan-Collins, L., Alon, N., Carreau, M., Bender, O., Demuth, I., Schindler, D., Pronk, J. C., Arwert, F., Hoehn, H., Digweed, M., Buchwald, M., and Joenje, H.. 1998. The Fanconi anaemia group G gene FANCG is identical with XRCC9. Nat. Genet. 20:281–283
   PubMed Web of Science ®Google Scholar
• Digweed, M., and Sperling, K.. 1996. Molecular analysis of Fanconi anaemia. Bioessays 18:579–585
   PubMedGoogle Scholar
• Essers, J., Hendriks, R. W., Swagemakers, S. M. A., Troelstra, C., de Wit, J., Bootsma, D., Hoeijmakers, J. H. J., and Kanaar, R.. 1997. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell 89:195–204
   PubMed Web of Science ®Google Scholar
• Essers, J., van Steeg, H., de Wit, J., Swagemakers, S. M. A., Vermeij, M., Hoeijmakers, J. H. J., and Kanaar, R.. 2000. Homologous and non-homologous recombination differentially affect DNA damage repair in mice. EMBO J. 19:1703–1710
   PubMed Web of Science ®Google Scholar
• Fanconi Anaemia/Breast Cancer Consortium. Positional cloning of the Fanconi anaemia group A gene. Nat. Genet. 14:324–328
   PubMedGoogle Scholar
• Haaf, T., Golub, E. I., Reddy, G., Radding, C. M., and Ward, D. C.. 1995. 1996. Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. Proc. Natl. Acad. Sci. USA 92:2298–2302
   PubMed Web of Science ®Google Scholar
• Haase, E., Riehl, D., Mack, M., and Brendel, M.. 1989. Molecular cloning of SNM1, a yeast gene responsible for a specific step in the repair of cross-linked DNA. Mol. Gen. Genet. 218:64–71
   PubMedGoogle Scholar
• Henriques, J. A., and Brendel, M.. 1990. The role of PSO and SNM genes in DNA repair of the yeast Saccharomyces cerevisiae. Curr. Genet. 18:387–393
   PubMedGoogle Scholar
• Henriques, J. A., Brozmanova, J., and Brendel, M.. 1997. Role of PSO genes in the repair of photoinduced interstrand cross-links and photooxidative damage in the DNA of the yeast Saccharomyces cerevisiae. J. Photochem. Photobiol. B 39:185–196
   PubMedGoogle Scholar
• Henriques, J. A., and Moustacchi, E.. 1981. Interactions between mutations for sensitivity to psoralen photoaddition (pso) and to radiation (rad) in Saccharomyces cerevisiae. J. Bacteriol. 148:248–256
   PubMed Web of Science ®Google Scholar
• Henriques, J. A., and Moustacchi, E.. 1980. Isolation and characterization of pso mutants sensitive to photo-addition of psoralen derivatives in Saccharomyces cerevisiae. Genetics 95:273–288
   PubMed Web of Science ®Google Scholar
• Hiramoto, T., Nakanishi, T., Sumiyoshi, T., Fukuda, T., Matsuura, S., Tauchi, H., Komatsu, K., Shibasaki, Y., Inui, H., Watatani, M., Yasutomi, M., Sumii, K., Kajiyama, G., Kamada, N., Miyagawa, K., and Kamiya, K.. 1999. Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. Oncogene 18:3422–3426
   PubMedGoogle Scholar
• Hoeijmakers, J. H. J.. Use of microneedle injection to study DNA repair in mammalian cells A laboratory manual of research procedures Friedberg, E. C., and Hanawalt, P. C. 3:133–150 Marcel Dekker, Inc., New York, N.Y
   Google Scholar
• Jachymczyk, W. J., von Borstel, R. C., Mowat, M. R., and Hastings, P. J.. 1981. 1988. Repair of interstrand cross-links in DNA of Saccharomyces cerevisiae requires two systems for DNA repair: the RAD3 system and the RAD51 system. Mol. Gen. Genet. 182:196–205
   PubMedGoogle Scholar
• Joenje, H., Oostra, A. B., Wijker, M., di Summa, F. M., van Berkel, C. G., Rooimans, M. A., Ebell, W., van Weel, M., Pronk, J. C., Buchwald, M., and Arwert, F.. 1997. Evidence for at least eight Fanconi anemia genes. Am. J. Hum. Genet. 61:940–944
   PubMed Web of Science ®Google Scholar
• Johnson, R. D., Liu, N., and Jasin, M.. 1999. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature 401:397–399
   PubMed Web of Science ®Google Scholar
• Johnson, S. W., Perez, R. P., Godwin, A. K., Yeung, A. T., Handel, L. M., Ozols, R. F., and Hamilton, T. C.. 1994. Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines. Biochem. Pharmacol. 47:689–697
   PubMed Web of Science ®Google Scholar
• Kaiser, P., Mansour, H. A., Greeten, T., Auer, B., Schweiger, M., and Schneider, R.. 1994. The human ubiquitin-conjugating enzyme UbcH1 is involved in the repair of UV-damaged, alkylated and cross-linked DNA. FEBS Lett. 350:1–4
   PubMedGoogle Scholar
• Kanaar, R., Hoeijmakers, J. H. J., and van Gent, D. C.. 1998. Molecular mechanisms of DNA double-strand break repair. Trends Cell. Biol. 8:483–489
   PubMed Web of Science ®Google Scholar
• Koken, M. H., Reynolds, P., Jaspers-Dekker, I., Prakash, L., Prakash, S., Bootsma, D., and Hoeijmakers, J. H.. 1991. Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6. Proc. Natl. Acad. Sci. USA 88:8865–8869
   PubMed Web of Science ®Google Scholar
• Larminat, F., and Bohr, V. A.. 1994. Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage. Nucleic Acids Res. 22:3005–3010
   PubMed Web of Science ®Google Scholar
• Lawley, P. D., and Phillips, D. H.. 1996. DNA adducts from chemotherapeutic agents. Mutat. Res. 355:13–40
   PubMed Web of Science ®Google Scholar
• Liu, N., Lamerdin, J. E., Tebbs, R. S., Schild, D., Tucker, J. D., Shen, M. R., Brookman, K. W., Siciliano, M. J., Walter, C. A., Fan, W., Narayana, L. S., Zhou, Z. Q., Adamson, A. W., Sorensen, K. J., Chen, D. J., Jones, N. J., and Thompson, L. H.. 1998. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol. Cell 1:783–793
   PubMed Web of Science ®Google Scholar
• Lo Ten Foe, J. R., Rooimans, M. A., Bosnoyan-Collins, L., Alon, N., Wijker, M., Parker, L., Lightfoot, J., Carreau, M., Callen, D. F., Savoia, A., Cheng, N. C., van Berkel, C. G., Strunk, M. H., Gille, J. J., Pals, G., Kruyt, F. A., Pronk, J. C., Arwert, F., Buchwald, M., and Joenje, H.. 1996. Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA. Nat. Genet. 14:320–323
   PubMed Web of Science ®Google Scholar
• Magana-Schwencke, N., and Averbeck, D.. 1991. Repair of exogenous (plasmid) DNA damaged by photoaddition of 8-methoxypsoralen in the yeast Saccharomyces cerevisiae. Mutat. Res. 251:123–131
   PubMedGoogle Scholar
• Magana-Schwencke, N., Henriques, J. A., Chanet, R., and Moustacchi, E.. 1982. The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: comparison of wild-type and repair-deficient strains. Proc. Natl. Acad. Sci. USA 79:1722–1726
   PubMed Web of Science ®Google Scholar
• Masutani, C., Sugasawa, K., Yanagisawa, J., Sonoyama, T., Ui, M., Enomoto, T., Takio, K., Tanaka, K., van der Spek, P. J., Bootsma, D. et al. 1994. Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23. EMBO J. 13:1831–1843
   PubMed Web of Science ®Google Scholar
• Meniel, V., Magana-Schwencke, N., and Averbeck, D.. 1995. Preferential repair in Saccharomyces cerevisiae rad mutants after induction of interstrand cross-links by 8-methoxypsoralen plus UVA. Mutagenesis 10:543–548
   PubMedGoogle Scholar
• Nagase, T., Miyajima, N., Tanaka, A., Sazuka, T., Seki, N., Sato, S., Tabata, S., Ishikawa, K., Kawarabayasi, Y., Kotani, H. et al. 1995. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1 (supplement). DNA Res. 2:51–59
   PubMedGoogle Scholar
• Paques, F., and Haber, J. E.. 1999. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 63:349–404
   PubMed Web of Science ®Google Scholar
• Patterson, G. H., Knobel, S. M., Sharif, W. D., Kain, S. R., and Piston, D. W.. 1997. Use of the green fluorescent protein and its mutants in quantitative fluorescence microscopy. Biophys. J. 73:2782–2790
   PubMed Web of Science ®Google Scholar
• Pierce, A. J., Johnson, R. D., Thompson, L. H., and Jasin, M.. 1999. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev. 13:2633–2638
   PubMed Web of Science ®Google Scholar
• Richter, D., Niegemann, E., and Brendel, M.. 1992. Molecular structure of the DNA cross-link repair gene SNM1 (PSO2) of the yeast Saccharomyces cerevisiae. Mol. Gen. Genet. 231:194–200
   PubMedGoogle Scholar
• Ruhland, A., Haase, E., Siede, W., and Brendel, M.. 1981. Isolation of yeast mutants sensitive to the bifunctional alkylating agent nitrogen mustard. Mol. Gen. Genet. 181:346–351
   PubMedGoogle Scholar
• Ruhland, A., Kircher, M., Wilborn, F., and Brendel, M.. 1981. A yeast mutant specifically sensitive to bifunctional alkylation. Mutat. Res. 91:457–462
   PubMedGoogle Scholar
• Scott, B. R., Pathak, M. A., and Mohn, G. R.. 1976. Molecular and genetic basis of furocoumarin reactions. Mutat. Res. 39:29–74
   PubMed Web of Science ®Google Scholar
• Siede, W., and Brendel, M.. 1982. Interactions among genes controlling sensitivity to radiation (RAD) and to alkylation by nitrogen mustard (SNM) in yeast. Curr. Genet. 5:33–38
   PubMedGoogle Scholar
• Simon, R., Burger, H., Brinkschmidt, C., Bocker, W., Hertle, L., and Terpe, H. J.. 1998. Chromosomal aberrations associated with invasion in papillary superficial bladder cancer. J. Pathol. 185:345–351
   PubMed Web of Science ®Google Scholar
• Strathdee, C. A., Gavish, H., Shannon, W. R., and Buchwald, M.. 1992. Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature 356:763–767
   PubMed Web of Science ®Google Scholar
• Swagemakers, S. M. A., Essers, J., de Wit, J., Hoeijmakers, J. H. J., and Kanaar, R.. 1998. The human Rad54 recombinational DNA repair protein is a double-stranded DNA-dependent ATPase. J. Biol. Chem. 273:28292–28297
   PubMed Web of Science ®Google Scholar
• Tan, T. L., Essers, J., Citterio, E., Swagemakers, S. M., de Wit, J., Benson, F. E., Hoeijmakers, J. H., and Kanaar, R.. 1999. Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation. Curr. Biol. 9:325–328
   PubMedGoogle Scholar
• Tebbs, R. S., Zhao, Y., Tucker, J. D., Scheerer, J. B., Siciliano, M. J., Hwang, M., Liu, N., Legerski, R. J., and Thompson, L. H.. 1995. Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene. Proc. Natl. Acad. Sci. USA 92:6354–6358
   PubMed Web of Science ®Google Scholar
• Thacker, J.. 1999. A surfeit of RAD51-like genes? Trends Genet. 15:166–168
   PubMedGoogle Scholar
• Tong, C. Y., Ng, H. K., Pang, J. C., Hui, A. B., Ko, H. C., and Lee, J. C.. 1999. Molecular genetic analysis of non-astrocytic gliomas. Histopathology 34:331–341
   PubMed Web of Science ®Google Scholar
• Van Houten, B.. 1990. Nucleotide excision repair in Escherichia coli. Microbiol. Rev. 54:18–51
   PubMedGoogle Scholar
• Whitney, M. A., Royle, G., Low, M. J., Kelly, M. A., Axthelm, M. K., Reifsteck, C., Olson, S., Braun, R. E., Heinrich, M. C., Rathbun, R. K., Bagby, G. C., and Grompe, M.. 1996. Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene. Blood 88:49–58
   PubMed Web of Science ®Google Scholar
• Wolter, R., Siede, W., and Brendel, M.. 1996. Regulation of SNM1, an inducible Saccharomyces cerevisiae gene required for repair of DNA cross-links. Mol. Gen. Genet. 250:162–168
   PubMedGoogle Scholar