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Cell Growth and Development

Estrogen Opposes the Apoptotic Effects of Bone Morphogenetic Protein 7 on Tissue Remodeling

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Pages 4626-4634 | Received 30 Nov 1999, Accepted 20 Mar 2000, Published online: 28 Mar 2023

REFERENCES

  • Arends, M. J., Morris, R. G., and Wyllie, A. H.. 1990. Apoptosis: the role of the endonuclease. Am. J. Pathol. 136:593–608
  • Arkell, R., and Beddington, R. S. P.. 1997. BMP-7 influences pattern and growth of the developing hindbrain of mouse embryos. Development 124:1–12
  • Berger, R. R., and Sanders, M. M.. 2000. Estrogen modulates HNF-3β mRNA levels in the developing oviduct. DNA Cell Biol. 19:103–112
  • Berman, J. R., McCarthy, M. M., and Kyprianou, N.. 1998. Effect of estrogen withdrawal on nitric oxide synthase expression and apoptosis in the rat vagina. Urology 51:650–655
  • Brodin, G., ten Dijke, P., Funa, K., Heldin, C.-H., and Landstrom, M.. 1999. Increased Smad expression and activation are associated with apoptosis in normal and malignant prostate after castration. Cancer Res. 59:2731–2738
  • Carr, B. R.. Disorders of the ovary and female reproductive tract, 8th ed. W. B. Saunders Company, Philadelphia, Pa
  • Chamberlain, E. M., and Sanders, M. M.. 1992. 1999. Identification of the novel player δEF1 in estrogen transcriptional cascades. Mol. Cell. Biol. 19:3600–3606
  • Cohrs, R., Goswami, B. B., and Sharma, O. K.. 1988. Occurrence of 2-5A and RNA degradation in the chick oviduct during rapid estrogen withdrawal. Biochemistry 27:3246–3252
  • Cohrs, R. J., Goswami, B. B., and Sharma, O. K.. 1988. Down regulation of c-myc, c-fos and erb-B during estrogen induced proliferation of the chick oviduct. Biochem. Biophys. Res. Commun. 150:82–88
  • Detre, S., Salter, J., Barnes, D. M., Riddler, S., Hills, M., Johnston, S. R. D., Gillett, C., A'Hern, R., and Dowsett, M.. 1999. Time-related effects of estrogen withdrawal on proliferation and cell death-related events in MCF-7 xenografts. Int. J. Cancer 81:309–313
  • Fitzgerald, M., and Schenk, T.. 1981. The sequence 5′-AAUAAA-3′ forms part of the recognition sequence for polyadenylation of late SV40 mRNAs. Cell 24:251–260
  • Galien, R., and Garcia, T.. 1997. Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-κB site. Nucleic Acids Res. 25:2424–2429
  • Gavrieli, Y., Sherman, Y., and Ben-Sasson, S. A.. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493–501
  • Glozak, M. A., and Rogers, M. B.. 1996. Specific induction of apoptosis in P19 embryonal carcinoma cells by retinoic acid and BMP2 or BMP4. Dev. Biol. (Orlando) 179:458–470
  • Gold, L. I., and Parekh, T. V.. 1999. Loss of growth regulation by transforming growth factor-β (TGF-β) in human cancers: studies on endometrial carcinoma. Semin. Reprod. Endocrinol. 17:73–92
  • Gong, J., Traganos, F., and Darzynkiewicz, Z.. 1994. A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal. Biochem. 218:314–319
  • Harada, S., Sampath, T. K., Aubin, J. E., and Rodan, G. A.. 1997. Osteogenic protein-1 up-regulation of the collagen X promoter activity is mediated by a MEF-2-like sequence and requires an adjacent AP-1 sequence. Mol. Endocrinol. 11:1832–1845
  • Hazama, M., Aono, A., Ueno, N., and Fujisawa, Y.. 1995. Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system. Biochem. Biophys. Res. Commun. 209:859–866
  • Helder, M. N., Karg, A., Bervoets, T. J. M., Vukicevic, S., Burger, E. H., D'Souza, R. N., Woltgens, J. H. M., Karsenty, G., and Bronckers, A. L. J. J.. 1998. Bone morphogenetic protein-7 (osteogenic protein-1, OP-1) and tooth development. J. Dent. Res. 77:545–554
  • Hermoso, M., Saez, J. C., and Villalon, M.. 1997. Identification of gap junctions in the oviduct and regulation of connexins during development and by sexual hormones. Eur. J. Cell Biol. 74:1–9
  • Heryanto, B., Yoshimura, Y., Tamura, T., and Okamoto, T.. 1997. Involvement of apoptosis and lysosomal hydrolase activity in the oviducal regression during induced molting in chickens: a cytochemical study for end labeling of fragmented DNA and acid phosphatase. Poultry Sci. 76:67–72
  • Hogan, B. L. M.. 1996. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev. 10:1580–1594
  • Houston, B., Thorpe, B. H., and Burt, D. W.. 1994. Molecular cloning and expression of bone morphogenetic protein-7 in the chick epiphyseal growth plate. J. Mol. Endocrinol. 13:289–301
  • Huang, D. C., Cory, S., and Strasser, A.. 1997. Bcl-2, Bcl-xL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death. Oncogene 14:405–414
  • Huet-Hudson, Y. M., Chakraborty, C., De, S. K., Suzuki, Y., Andrews, G. K., and Dey, S. K.. 1990. Estrogen regulates the synthesis of epidermal growth factor in mouse uterine epithelial cells. Mol. Endocrinol. 4:510–523
  • Ignar-Trowbridge, D. M., Pimentel, M., Teng, C. T., Korach, K. S., and McLachlan, J. A.. 1995. Cross talk between peptide growth factor and estrogen receptor signaling systems. Environ. Health Perspect. 103:35–38
  • Jaffe, R. C., Arias, E. B., O'Day-Bowman, M. B., Donnelly, K. M., Mavrogianis, P. A., and Verhage, H. G.. 1996. Regional distribution and hormone control of estrogen-dependent oviduct-specific glycoprotein messenger ribonucleic acid in the baboon (Papio anubis). Biol. Reprod. 55:421–426
  • Jena, N., Martin-Seisdedos, C., McCue, P., and Croce, C. M.. 1997. BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye. Exp. Cell Res. 230:28–37
  • Kepa, J. K., Neely, C. I., Jacobsen, B. M., Bruder, J. M., McDonnell, D. P., Leslie, K. K., and Wierman, M. E.. 1994. Estrogen receptor mediated repression of rat gonadotropin releasing hormone (GnRH) promoter activity in hypothalamic cells. Endocr. Rev. 2:1–10
  • Keri, R. A., Andesen, B., Kennedy, G. C., Hamernik, D. L., Clay, C. M., Brace, A. D., Nett, T. M., Notides, A. C., and Nilson, J. H.. 1991. Estradiol inhibits transcription of the human glycoprotein hormone α-subunit despite the absence of a high affinity binding site for estrogen receptor. Mol. Endocrinol. 5:725–733
  • Kurebayashi, S., Miyashita, Y., Hirose, T., Kasayama, S., Akira, S., and Kishimoto, T.. 1997. Characterization of mechanisms of interleukin-6 repression by estrogen receptor. J. Steroid Biochem. Mol. Biol. 60:11–17
  • Kyprianou, N., and Isaacs, J. T.. 1988. Activation of programmed cell death in the rat ventral prostate after castration. Endocrinology 122:552–562
  • Lincz, L. F.. 1998. Deciphering the apoptotic pathway: all roads lead to death. Immunol. Cell Biol. 76:1–19
  • Llen, R. T., Hunter, W. J.3rd, and Agrawal, D. K.. 1997. Morphological and biochemical characterization and analysis of apoptosis. J. Pharmacol. Toxicol. Methods 37:215–228
  • Loo, D. T., and Rillema, J. R.. 1998. Measurement of cell death. Methods Cell Biol. 57:251–264
  • Luo, G., Hofmann, C., Bronckers, A. L. J. J., Sohocki, M., Bradley, A., and Karsenty, G.. 1995. BMP-7 in an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev. 9:2808–2820
  • Macias, D., Ganan, Y., Sampath, T. K., Piedra, M. E., Ros, M. A., and Hurle, J. M.. 1997. Role of BMP2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development. Development 124:1109–1117
  • Macias-Silva, M., Hoodless, P. A., Tang, S. J., Buchwald, M., and Wrana, J. L.. 1998. Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J. Biol. Chem. 273:25628–25636
  • Malayer, J. R., and Gorski, J.. 1993. An integrated model of estrogen receptor action. Domest. Anim. Endocrinol. 10:159–177
  • Malayer, J. R., and Woods, V. M.. 1998. Expression of estrogen receptor and maintenance of hormone-responsive phenotype in bovine fetal uterine cells. Domest. Anim. Endocrinol. 15:141–154
  • McLachlan, J. A., Nelson, K. G., Takahashi, T., Bossert, N. L., Newbold, R. R., and Korach, K. S.. 1991. Estrogens and growth factors in the development, growth, and function of the female reproductive tract. Springer-Verlag, New York, N.Y
  • Medema, J. P., Scaffidi, C., Kischkel, F. C., Shevchenko, A., Mann, M., Krammer, P. H., and Peter, M. E.. 1997. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:2794–2804
  • Miller, C. D., and Miller, W. L.. 1996. Transcriptional repression of the ovine follicle-stimulating hormone-β gene by 17β-estradiol. Endocrinology 137:3437–3446
  • Murphy, L. J., Murphy, L. C., and Friesen, H. G.. 1987. Estrogen induces insulin-like growth factor-I expression in the rat uterus. Mol. Endocrinol. 1:445–450
  • Nelson, K. G., Takahashi, T., Lee, D. C., Luetteke, N. C., Bossert, N. L., Ross, K., Eitzman, B. E., and McLachlan, J. A.. 1992. Transforming growth factor-α is a potential mediator of estrogen action in the mouse uterus. Endocrinology 131:1657–1664
  • Newmeyer, D. D., Farschon, D. M., and Reed, J. C.. 1994. Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell 79:353–364
  • Nordstrom, L. A., Dean, D. M., and Sanders, M. M.. 1993. A complex array of double-stranded and single-stranded DNA-binding proteins mediates induction of the ovalbumin gene by steroid hormones. J. Biol. Chem. 268:13193–13202
  • Nunez, G., Benedict, M. A., Hu, Y., and Inohara, N.. 1998. Caspases: the proteases of the apoptotic pathway. Oncogene 17:3237–3245
  • Ozkaynak, E., Jin, D. F., Jelic, M., Vukicevic, S., and Oppermann, H.. 1997. Osteogenic protein-1 mRNA in the uterine endometrium. Biochem. Biophys. Res. Commun. 234:242–246
  • Ozkaynak, E., Rueger, D. C., Drier, E. A., Corbett, C., Ridge, R. J., Sampath, T. K., and Oppermann, H.. 1990. OP-1 cDNA encodes an osteogenic protein in the TGF-β family. EMBO J. 9:2085–2093
  • Ozkaynak, E., Schnegelsberg, P. N. J., and Oppermann, H.. 1991. Murine osteogenic protein (OP-1): high levels of mRNA in kidney. Biochem. Biophys. Res. Commun. 179:116–123
  • Porter, A. G., and Janicke, R. U.. 1999. Emerging roles of caspase-3 in apoptosis. Cell Death Differ. 6:99–104
  • Ray, P., Ghosh, S. K., Zhang, D.-H., and Ray, A.. 1997. Repression of interleukin-6 gene expression by 17β-estradiol: inhibition of the DNA-binding activity of the transcription factors NF-IL6 and NF-κB by the estrogen receptor. FEBS Lett. 409:79–85
  • Reinhardt, K. C., Dubey, R. K., Mummery, C. L., van Rooijen, M., Keller, P. J., and Marinella, R.. 1998. Synthesis and regulation of leukaemia inhibitory factor in cultured bovine oviduct cells by hormones. Mol. Human Reprod. 4:301–308
  • Reiss, M., and Barcellos-Hoff, M. H.. 1997. Transforming growth factor-β in breast cancer: a working hypothesis. Breast Cancer Res. Treat. 45:81–95
  • Rochwerger, L., and Buchwald, M.. 1993. Stimulation of the cystic fibrosis transmembrane regulator expression by estrogen in vivo. Endocrinology 133:921–930
  • Russo, M. A., Guerriero, V., and Means, A. R.. 1987. Hormonal regulation of a chicken oviduct messenger ribonucleic acid that shares a common domain with gizzard myosin light chain kinase. Mol. Endocrinol. 1:60–67
  • Sampath, T. K., Coughlin, J. E., Whetstone, R. M., Banach, D., Corbett, C., Ridge, R. J., Ozkaynak, E., Oppermann, H., and Rueger, R. C.. 1990. Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-β superfamily. J. Biol. Chem. 265:13198–13205
  • Sampath, T. K., Maliakal, J. C., Hauschka, P. V., Jones, W. K., Sasak, H., Tucker, R. F., White, K. H., Coughlin, J. E., Tucker, M. M., Pang, R. H. L., Corbett, C., Ozkaynak, E., Oppermann, H., and Rueger, D. C.. 1992. Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro. J. Biol. Chem. 267:20352–20362
  • Sampath, T. K., and Reddi, A. H.. 1981. Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation. Proc. Natl. Acad. Sci. USA 78:7599–7603
  • Sanders, M. M., and McKnight, G. S.. 1985. Chicken egg white genes: multihormonal regulation in a primary cell culture system. Endocrinology 116:398–405
  • Sanders, M. M., and McKnight, G. S.. 1988. Positive and negative regulatory elements control the steroid-responsive ovalbumin promoter. Biochemistry 27:6550–6557
  • Schell, D. L., Mavrogianis, P. A., Fazleabas, A. T., and Verhage, H. G.. 1994. Epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor localization in the baboon (Papio anubis) oviduct during steroid treatment and the menstrual cycle. J. Soc. Gynecol. Investig. 1:269–276
  • Shepherd, J. H., Mulvihill, E. R., Thomas, P. S., and Palmiter, R. D.. 1980. Commitment of chick oviduct tubular gland cells to produce ovalbumin mRNA during hormonal withdrawal and restimulation. J. Cell Biol. 87:142–151
  • Shoham, Z., and Schachter, M.. 1996. Estrogen biosynthesis--regulation, action, remote effects, and value of monitoring in ovarian stimulation cycles. Fertility Sterility 65:687–701
  • Smale, S. T.. 1997. Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes. Biochim. Biophys. Acta 1351:73–88
  • Smith, C. L.. 1998. Cross-talk between peptide growth factor and estrogen signaling pathways. Biol. Reprod. 58:627–632
  • Takahashi, T., Eitzman, B., Bossert, N. L., Walmer, D., Sparrow, K., Flanders, K. C., McLachlan, J., and Nelson, K. G.. 1994. Transforming growth factors β1, β2, and β3 messenger RNA and protein expression in mouse uterus and vagina during estrogen-induced growth: a comparison to other estrogen-regulated genes. Cell Growth Differ. 5:919–935
  • Tanabe, Y., Ogawa, T., and Nakamura, T.. 1981. The effect of short term starvation on pituitary and plasma LH, plasma estradiol and progesterone, and on pituitary response to LH-RH in the laying hens. Gen. Comp. Endocrinol. 43:392–398
  • Tang, S. G., Hoodless, P. A., Lu, Z., Breitman, M. L., McInnes, R. R., Wrana, J. L., and Buchwald, M.. 1998. The Tlx-2 homeobox gene is a downstream target of BMP signaling and is required for mouse mesoderm development. Development 125:1877–1887
  • Thomas, R., Anderson, W. A., Raman, V., and Reddi, A. H.. 1998. Androgen-dependent gene expression of bone morphogenetic protein 7 in mouse prostate. Prostate 37:236–245
  • Tomkinson, A., Reeve, J., Shaw, R. W., and Noble, B. S.. 1997. The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone. J. Clin. Endocrinol. Methods 82:3128–3135
  • Urist, M. R.. 1965. Bone: formation by autoinduction. Science 150:893–899
  • Volk, S. W., Luvalle, P., Leask, T., and LeBoy, P. S.. 1998. A BMP responsive transcriptional region in the chicken type X collagen gene. J. Bone Miner. Res. 13:1521–1529
  • Wada, K., Nomura, S., Morii, E., Kitamura, Y., Nishizawa, Y., Miyake, A., and Terada, N.. 1996. Changes in levels of mRNAs of transforming growth factor (TGF)-β1, -β2, -β3, TGF-β type II receptor and sulfated glycoprotein-2 during apoptosis of mouse uterine epithelium. J. Steroid Biochem. Mol. Biol. 59:367–375
  • Wang, S., Krinks, M., Kleinwaks, L., and Moos, J. M.. 1997. A novel Xenopus homologue of bone morphogenetic protein-7 (BMP-7). Genes Function 1:259–271

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