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Cell and Organelle Structure and Assembly

Mutations in a tRNA Import Signal Define Distinct Receptors at the Two Membranes of Leishmania Mitochondria

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Pages 7410-7417 | Received 29 Feb 2000, Accepted 20 Jun 2000, Published online: 28 Mar 2023

REFERENCES

  • Adhya, S., Ghosh, T., Das, A., Bera, S. K., and Mahapatra, S.. 1997. Role of an RNA binding protein in import of tRNA into Leishmania mitochondria. J. Biol. Chem. 272:21396–21402
  • Chiu, N., Chiu, A., and Suyama, Y.. 1975. Native and imported transfer RNA in mitochondria. J. Mol. Biol. 94:37–50
  • Das, S., and Adhya, S.. 1990. Organization and chromosomal localization of β-tubulin genes in Leishmania donovani. J. Biosci. 15:239–248
  • Ghosh, A., Ghosh, T., Ghosh, S., Das, S., and Adhya, S.. 1994. Interaction of small ribosomal and transfer RNAs with a protein from Leishmania donovani. Nucleic Acids Res. 22:1663–1669
  • Gray, M. W., Burger, G., and Lang, B. F.. 1999. Mitochondrial evolution. Science 283:1476–1481
  • Gray, M. W., Lang, B. F., Cedergren, R., Golding, G. B., Lemieux, C., Sankoff, D., Turmel, M., Brossard, N., De Lage, E., Littlejohn, T. G., Plante, I., Rioux, P., Saint-Louis, D., Zhu, Y., and Burger, G.. 1998. Genome structure and gene content in protist mitochondrial DNAs. Nucleic Acids Res. 26:865–878
  • Hancock, K., and Hajduk, S. L.. 1990. The mitochondrial tRNAs of Trypanosoma brucei are nuclear encoded. J. Biol. Chem. 265:19203–19215
  • Hauser, R., and Schneider, A.. 1995. tRNAs are imported into the mitochondria of Trypanosoma brucei independent of their genomic context and of their genetic origin. EMBO J. 14:4212–4220
  • Kumar, R., Marechal-Drouard, L., Akama, K., and Small, I.. 1996. Striking differences in mitochondrial tRNA import between different plant species. Mol. Gen. Genet. 252:404–411
  • Lima, B. D., and Simpson, L.. 1996. Sequence dependent in vivo importation of tRNAs into the mitochondrion of Leishmania tarentolae. RNA 2:429–440
  • Lye, L.-F., Chen, D.-H. T., and Suyama, Y.. 1993. Selective import of nuclear-encoded tRNAs into mitochondria of the protozoan Leishmania tarentolae. Mol. Biochem. Parasitol. 58:233–246
  • Mahapatra, S., and Adhya, S.. 1996. Import of RNA into Leishmania mitochondria occurs through direct interaction with membrane-bound receptors. J. Biol. Chem. 271:20432–20437
  • Mahapatra, S., Ghosh, S., Bera, S. K., Ghosh, T., Das, A., and Adhya, S.. 1998. The D arm of tRNATyr is necessary and sufficient for import into Leishmania mitochondria in vitro. Nucleic Acids Res. 26:2037–2041
  • Mahapatra, S., Ghosh, T., and Adhya, S.. 1994. Import of small RNAs into Leishmania mitochondria in vitro. Nucleic Acids Res. 22:3381–3386
  • Martin, R. P., Schneller, J.-M., Stahl, A. J., and Dirheimer, G.. 1979. Import of nuclear deoxyribonucleic acid coded lysine-accepting transfer ribonucleic acid (anticodon C-U-U) into yeast mitochondria. Biochemistry 18:4600–4605
  • Mottram, J. C., Bell, S. D., and Barry, D. J.. 1991. tRNAs of Trypanosoma brucei: unusual gene organization and mitochondrial importation. J. Biol. Chem. 266:18313–18317
  • Mukherjee, S., Bhattacharyya, S. N., and Adhya, S.. 1999. Stepwise transfer of tRNA through the double membrane of Leishmania mitochondria. J. Biol. Chem. 274:31249–31255
  • Nabholz, C. E., Horn, E. K., and Schneider, A.. 1999. tRNAs and proteins are imported into mitochondria of Trypanosoma brucei by two distinct mechanisms. Mol. Biol. Cell 10:2547–2557
  • Ragan, C. I., Wilson, M. T., Darley-Usmar, V. M., and Lowe, P. N.. 1987. Sub-fractionation of mitochondria and isolation of the proteins of oxidative phosphorylation Mitochondria, a practical approach. Darley-Usmar, V. M., Rickwood, D., and Wilson, M. T. 79–112 IRL Press, Oxford, England
  • Rusconi, C. P., and Cech, T. R.. 1996. The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena. Genes Dev. 10:2870–2880
  • Schneider, A., Martin, J., and Agabian, N.. 1994. A nuclear encoded tRNA of Trypanosoma brucei is imported into mitochondria. Mol. Cell. Biol. 14:2317–2322
  • Shi, X., Chen, D. H.-T., and Suyama, Y.. 1994. A nuclear tRNA gene cluster in the protozoan Leishmania tarentolae and differential distribution of nuclear-encoded tRNAs between the cytosol and mitochondria. Mol. Biochem. Parasitol. 65:23–37
  • Simpson, A. M., Suyama, Y., Dewes, H., Campbell, D., and Simpson, L.. 1989. Kinetoplastid mitochondria contain functional tRNAs which are encoded in nuclear DNA and also contain small minicircle and maxicircle transcripts of unknown function. Nucleic Acids Res. 17:5427–5445
  • Volckaert, G., and Fiers, W.. 1977. Micro thin-layer techniques for rapid sequence analysis of 32P-labeled RNA: double digestion and pancreatic ribonuclease analyses. Anal. Biochem. 83:228–239
  • Yermovsky-Kammerer, A. E., and Hajduk, S. L.. 1999. In vitro import of a nuclearly encoded tRNA into the mitochondrion of Trypanosoma brucei. Mol. Cell. Biol. 19:6253–6259
  • Zuker, M.. 1989. Computer prediction of RNA structure. Methods Enzymol. 180:262–268

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