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Mammalian Genetic Models with Minimal or Complex Phenotypes

Gene Disruption of Tissue Transglutaminase

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Pages 148-155 | Received 20 Jul 2000, Accepted 28 Sep 2000, Published online: 28 Mar 2023

REFERENCES

  • Achyuthan, K. E., and C. S. Greenberg. 1987. Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity. J. Biol. Chem. 262:1901–1906.
  • Amendola, A., M. L. Gougeon, F. Poccia, A. Bondurand, L. Fesus, and M. Piacentini. 1996. Induction of “tissue” transglutaminase in HIV-pathogenesis: evidence for high rate of apoptosis of CD4+ T lymphocytes and accessory cells in lymphoid tissues. Proc. Natl. Acad. Sci. USA 93:11057–11062.
  • Bernassola, F., C. Scheurpflug, I. Herr, P. H. Krammer, K. M. Debatin, and G. Melino. 1999. Induction of apoptosis by IFNgamma in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit. Cell Death Differ. 6:652–660.
  • Candi, E., G. Melino, A. Lahm, R. Ceci, A. Rossi, I.-G. Kim, B. Ciani, and P. M. Steinert. 1998. Transglutaminase 1 mutations in lamellar ichthyosis. J. Biol. Chem. 273:13693–13702.
  • Cecconi, F.. 1999. Apaf1 and the apoptotic machinery. Cell Death Differ. 6:1087–1098.
  • De Laurenzi, V., and G. Melino. 2000. Apoptosis. The little devil of death. Nature 406:135–136.
  • Dieterich, W., T. Ehnis, M. Bauer, P. Donner, U. Volta, E. O. Riecken, and D. Schuppan. 1997. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat. Med. 3:797–801.
  • Donehower, L. A., M. Harvey, B. L. Slagle, M. J. McArthur, C. A. Montgomery Jr., J. S. Butel, and A. Bradley. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215–221.
  • Fesus, L., V. Thomazy, F. Autuori, M. P. Ceru', E. Tarcsa, and M. Piacentini. 1989. Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action. FEBS Lett. 245:150–154.
  • Fesus, L., P. J. A. Davies, and M. Piacentini. 1991. Apoptosis: molecular mechanisms in programmed cell death. Eur. J. Cell Biol. 56:170–177.
  • Hettasch, J. M., N. Bandarenko, J. L. Burchette, T. S. Lai, J. R. Marks, Z. A. Haroon, K. Peters, M. W. Dewhirst, J. D. Iglehart, and C. S. Greenberg. 1996. Tissue transglutaminase expression in human breast cancer. Lab. Investig. 75:637–645.
  • Huber, M., I. Rettler, K. Bernasconi, E. Frenk, S. P. Lavrijsen, M. Ponec, A. Bon, S. Lautenschlager, D. F. Schorderet, and D. Hohl. 1995. Mutations of keratinocyte transglutaminase in lamellar ichthyosis. Science 267:525–528.
  • Igarashi, S., R. Koide, T. Shimohata, M. Yamada, Y. Hayashi, H. Takano, H. Date, M. Oyake, T. Sato, A. Sato, S. Egawa, T. Ikeuchi, H. Tanaka, R. Nakano, K. Tanaka, I. Hozumi, T. Inuzuka, H. Takahashi, and S. Tsuji. 1998. Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch. Nat. Genet. 18:111–117.
  • Kahlem, P., H. Green, and P. Djian. 1998. Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine. Mol. Cell 1:595–601.
  • Kim, S. Y., P. Grant, J. H. Lee, H. C. Pant, and P. M. Steinert. 1999. Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's disease. J. Biol. Chem. 274:30715–30721.
  • Kuida, K., J. A. Lippke, G. Ku, M. W. Harding, D. J. Livingstone, M. S.-S. Su, and R. A. Flavell. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 281:2000–2002.
  • Kumar, S.. 1999. Mechanisms mediating caspase activation in cell death. Cell Death Differ. 6:1060–1066.
  • Li, P., H. Allen, S. Banerjee, S. Franklin, L. Herzog, C. Johnstone, J. McDowell, M. Paskind, L. Rodman, J. Salfeld, E. Townes, D. Tracey, S. Wardwell, F.-Y. Wei, W. W. Wong, R. Kamen, and T. Seshadri. 1995. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL beta and resistant to endotoxic shock. Cell 80:401–411.
  • Lorand, L.. 1998. DRPLA aggregation and transglutaminase, revisited. Nat. Genet. 20:231
  • Matsuki, M., F. Yamashita, A. Ishida-Yamamoto, K. Yamada, C. Kinoshita, S. Fushiki, E. Ueda, Y. Morishima, K. Tabata, H. Yasuno, M. Hashida, H. Iizuka, M. Ikawa, M. Okabe, G. Kondoh, T. Kinoshita, J. Takeda, and K. Yamanishi. 1998. Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase). Proc. Natl. Acad. Sci. USA 95:1044–1049.
  • Melino, G., M. G. Farrace, M. P. Ceru', and M. Piacentini. 1988. Correlation between transglutaminase activity and polyamine levels in human neuroblastoma cells. Effect of retinoic acid and alpha-difluoromethylornithine. Exp. Cell Res. 179:429–445.
  • Melino, G., M. Annicchiarico-Petruzzelli, L. Piredda, E. Candi, V. Gentile, P. J. A. Davies, and M. Piacentini. 1994. Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol. Cell. Biol. 14:6584–6596.
  • Melino, G., F. Bernassola, M. T. Corasaniti, R. A. Knight, G. Nistico, and A. Finazzi-Agro. 1997. S-nitrosylation regulates apoptosis. Nature 388:432–433.
  • Melino, G., M. Draoui, M. Piacentini, L. Bellincampi, F. Bernassola, U. Reichert, and P. Cohen. 1997. Retinoic acid receptors a and g mediate tissue-transglutaminase induction in human neuroblastoma cells undergoing apoptosis. Exp. Cell Res. 255:55–61.
  • Melino, G., and M. Piacentini. 1998. Tissue transglutaminase in apoptosis: a downstream or a multifunctional upstream effector?. FEBS Lett. 430:59–63.
  • Melino, G., E. Candi, and P. M. Steinert. 2000. Assay for transglutaminases in cell death. Methods Enzymol 322:433–472.
  • Molberg, O., S. N. Mcadam, R. Korner, H. Quarsten, C. Kristiansen, L. Madsen, L. Fugger, H. Scott, O. Noren, P. Roepstorff, K. E. Lundin, H. Sjostrom, and L. M. Sollid. 1998. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Nat. Med. 4:713–717.
  • Nagy, L., M. Saydak, N. Shipley, S. Lu, J. P. Basilion, Z. H. Yan, P. Syka, R. Chandraratna, R. Heyman, and P. J. A. Davies. 1996. Identification and characterization of a versatile retinoid response element (RARE/RXRE) in the promoter of the mouse tissue transglutaminase gene. J. Biol. Chem. 271:4355–4365.
  • Nagy, L., V. A. Thomazy, M. M. Saydak, J. P. Stein, and P. J. A. Davies. 1997. The promoter of mouse tissue transglutaminase gene directs tissue-specific, retinoid-regulated and apoptosis-linked expression. Cell Death Differ. 4:534–547.
  • Nakaoka, H., D. M. Perez, K. J. Baek, T. Das, A. Husain, K. Misono, M. Im, and R. M. Graham. 1994. Gh: a GTP-binding protein with transglutaminase activity and receptor signaling function. Science 264:1593–1596.
  • Nemes, Z. Jr., R. R. Friis, D. Aeschlimann, S. Saurer, M. Paulsson, and L. Fesus. 1996. Expression and activation of tissue transglutaminase in apoptotic cells of involuting rodent mammary tissue. Eur. J. Cell Biol. 70:125–133.
  • Piacentini, M., L. Fesus, M. G. Farrace, L. Ghibelli, L. Piredda, and G. Melino. 1991. The expression of “tissue” transglutaminase in two human cancer cell lines is related with the programmed cell death (apoptosis). Eur. J. Cell Biol. 54:246–254.
  • Piacentini, M., M. Annicchiarico-Petruzzelli, S. Oliverio, L. Piredda, J. L. Biedler, and G. Melino. 1992. Phenotype-specific “tissue” transglutaminase regulation in human neuroblastoma cells in response to retinoic acid: correlation with cell death by apoptosis. Int. J. Cancer 52:271–278.
  • Piacentini, M., L. Fesus, and G. Melino. 1993. Multiple cell cycle access to the apoptotic death programme in human neuroblastoma cells. FEBS Lett. 320:150–154.
  • Piacentini, M., and F. Autuori. 1994. Immunohistochemical localization of tissue transglutaminase and Bcl-2 in rat uterine tissues during embryo implantation and post-partum involution. Differentiation 57:51–61.
  • Piacentini, M.. 1995. Tissue transglutaminase: a candidate effector element of physiological cell death. Curr. Top. Microbiol. Immunol. 200:163–176.
  • Piacentini, M., L. Piredda, D. Starace, M. Annicchiarico-Petruzzelli, M. Mattel, S. Oliverio, M. G. Farrace, and G. Melino. 1996. Differential growth properties of S- and N-type human neuroblastoma cell variants transplanted into SCID mice: correlation with apoptosis and effect of ethanol. J. Pathol. 180:415–422.
  • Piacentini, M., and V. Colizzi. 1999. Tissue transglutaminase: apoptosis versus autoimmunity. Immunol. Today 20:130–134.
  • Piredda, L., A. Amendola, V. Colizzi, P. J. A. Davies, M. G. Farrace, M. Fraziano, V. Gentile, I. Uray, M. Piacentini, and L. Fesus. 1997. Lack of “tissue” transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice. Cell Death Differ. 4:463–472.
  • Piredda, L., M. G. Farrace, M. Lo Bello, W. Malorni, G. Melino, R. Petruzzelli, and M. Piacentini. 1999. Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis. FASEB J. 13:355–364.
  • Ritter, S. J., and P. J. Davies. 1998. Identification of a transforming growth factor-beta1/bone morphogenetic protein 4 (TGF-beta1/BMP4) response element within the mouse tissue transglutaminase gene promoter. J. Biol. Chem. 273:12798–12806.
  • Russell, L. J., J. J. DiGiovanna, G. R. Rogers, P. M. Steinert, N. Hashem, J. G. Compton, and S. J. Bale. 1995. Mutations in the gene for transglutaminase 1 in autosomal recessive lamellar ichthyosis. Nat. Genet. 9:279–283.
  • Saudou, F., S. Finkbeiner, D. Devys, and M. E. Greenberg. 1998. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 95:55–66.
  • Steinert, P. M.. 1995. A model for the hierarchical structure of the human epidermal cornified cell envelope. Cell Death Differ. 2:33–40.
  • Steinert, P. M., E. Candi, E. Tarcsa, L. N. Marekov, M. Sette, M. Paci, B. Ciani, P. Guerrieri, and G. Melino. 1999. Transglutaminase crosslinking and structural studies of the human small proline rich 3 protein. Cell Death Differ. 6:916–930.
  • Strange, R., F. Li, S. Saurer, A. Bukhard, and R. R. Friis. 1992. Apoptotic cell death and tissue remodelling during mouse mammary gland involution. Development 115:49–58.
  • Szondy, Z., P. Molnar, Z. Nemes, M. Boyiardzis, N. Kedei, R. Toth, and L. Fesus. 1997. Differential expression of transglutaminase during in vivo apoptosis of thymocytes induced via distinct signalling pathways. FEBS Lett. 404:307–313.
  • Thomazy, V. A., and P. J. Davies. 1999. Expression of tissue transglutaminase in the developing chicken limb is associated both with apoptosis and endochondral ossification. Cell Death Differ. 6:146–154.
  • Tybulewicz, V. L., C. E. Crawford, P. K. Jackson, R. T. Bronson, and R. C. Mulligan. 1991. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65:1153–1163.
  • Zhang, L. X., K. J. Mills, M. I. Dawson, S. J. Collins, and A. M. Jetten. 1995. Evidence for the involvement of retinoic acid receptor RAR alpha-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids. J. Biol. Chem. 270:6022–6029.
  • Zheng, T. S., S. Hunot, K. Kuida, and R. A. Flavell. 1999. Caspase knockouts: matters of life and death. Cell Death Differ. 6:1043–1053.

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