Requirement of DNA Polymerase η for Error-Free Bypass of UV-Induced CC and TC Photoproducts

REFERENCES

• Armstrong, J. D., and B. A. Kunz. 1990. Site and strand specificity of UVB mutagenesis in the SUP4-o gene of yeast. Proc. Natl. Acad. Sci. USA 87:9005–9009.
   PubMedGoogle Scholar
• Bourre, F., G. Renault, and A. Sarasin. 1987. Sequence effect on alkali-sensitive sites in UV-irradiated SV40 DNA. Nucleic Acids Res. 15:8861–8875.
   PubMedGoogle Scholar
• Brash, D. E.. 1997. Sunlight and the onset of skin cancer. Trends Genet. 13:410–414.
   PubMed Web of Science ®Google Scholar
• Brash, D. E., and W. A. Haseltine. 1982. UV-induced mutation hotspots occur at DNA damage hotspots. Nature 298:189–192.
   PubMed Web of Science ®Google Scholar
• Brash, D. E., S. Seetharam, K. H. Kraemer, M. M. Seidman, and A. Bredberg. 1987. Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells. Proc. Natl. Acad. Sci. USA 84:3782–3786.
   PubMed Web of Science ®Google Scholar
• Canella, K. A., and M. M. Seidman. 2000. Mutation spectra in supF: approaches to elucidating sequence context effects. Mutat. Res. 450:61–73.
   PubMedGoogle Scholar
• Ciarrocchi, G., and A. M. Pedrini. 1982. Determination of pyrimidine dimer unwinding angle by measurement of DNA electrophoretic mobility. J. Mol. Biol. 155:177–183.
   PubMedGoogle Scholar
• Friedberg, E. C., W. J. Feaver, and V. L. Gerlach. 2000. The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance. Proc. Natl. Acad. Sci. USA 97:5681–5683.
   PubMed Web of Science ®Google Scholar
• Gietz, R. D., and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527–534.
   PubMed Web of Science ®Google Scholar
• Glass, A. G., and R. N. Hoover. 1989. The emerging epidemic of melanoma and squamous cell skin cancer. JAMA 262:2097–2100.
   PubMed Web of Science ®Google Scholar
• Husain, I., J. Griffith, and A. Sancar. 1988. Thymine dimers bend DNA. Proc. Natl. Acad. Sci. USA 85:2558–2562.
   PubMed Web of Science ®Google Scholar
• Johnson, R. E., C. M. Kondratick, S. Prakash, and L. Prakash. 1999. hRAD30 mutations in the variant form of xeroderma pigmentosum. Science 285:263–265.
   PubMed Web of Science ®Google Scholar
• Johnson, R. E., S. Prakash, and L. Prakash. 1999. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη. Science 283:1001–1004.
   PubMed Web of Science ®Google Scholar
• Johnson, R. E., S. Prakash, and L. Prakash. 1999. Requirement of DNA polymerase activity of yeast Rad30 protein for its biological function. J. Biol. Chem. 274:15975–15977.
   PubMedGoogle Scholar
• Johnson, R. E., M. T. Washington, L. Haracska, S. Prakash, and L. Prakash. 2000. Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions. Nature 406:1015–1019.
   PubMed Web of Science ®Google Scholar
• Johnson, R. E., M. T. Washington, S. Prakash, and L. Prakash. 2000. Fidelity of human DNA polymerase η. J. Biol. Chem. 275:7447–7450.
   PubMed Web of Science ®Google Scholar
• Kim, J.-K., and B.-S. Choi. 1995. The solution structure of DNA duplex-decamer containing the (6-4) photoproduct of thymidyl(3′→5′)thymidine by NMR and relaxation matrix refinement. Eur. J. Biochem. 228:849–854.
   PubMedGoogle Scholar
• Kim, J.-K., D. Patel, and B.-S. Choi. 1995. Contrasting structural impacts induced by cis-syn cyclobutane dimer and (6-4) adduct in DNA duplex decamers: implication in mutagenesis and repair activity. Photochem. Photobiol. 62:44–50.
   PubMed Web of Science ®Google Scholar
• Lee, G. S.-F., E. A. Savage, R. G. Ritzel, and R. C. von Borstel. 1988. The base-alteration spectrum of spontaneous and ultraviolet radiation-induced forward mutations in the URA3 locus of Saccharomyces cerevisiae. Mol. Gen. Genet. 214:396–404.
   PubMedGoogle Scholar
• Lee, J.-H., G.-S. Hwang, and B.-S. Choi. 1999. Solution structure of a DNA decamer duplex containing the stable 3′ T.G base pair of the pyrimidine(6-4)pyrimidone photoproduct [(6-4) adduct]: implications for the highly specific 3′ T → C transition of the (6-4) adduct. Proc. Natl. Acad. Sci. USA 96:6632–6636.
   PubMed Web of Science ®Google Scholar
• Magnus, K.. 1991. The Nordic profile of skin cancer incidence. A comparative epidemiological study of the three main types of skin cancer. Int. J. Cancer 47:12–19.
   PubMedGoogle Scholar
• Masutani, C., R. Kusumoto, A. Yamada, N. Dohmae, M. Yokoi, M. Yuasa, M. Araki, S. Iwai, K. Takio, and F. Hanaoka. 1999. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η. Nature 399:700–704.
   PubMed Web of Science ®Google Scholar
• Oikarinen, A., and A. Raitio. 2000. Melanoma and other skin cancers in circumpolar areas. Int. J. Circumpolar Health 59:52–56.
   PubMedGoogle Scholar
• Setlow, R. B., W. L. Carrier, and F. J. Bollum. 1965. Pyrimidine dimers in UV-irradiated poly dI:dC. Proc. Natl. Acad. Sci. USA 53:1111–1118.
   PubMedGoogle Scholar
• Tessman, I., M. A. Kennedy, and S.-K. Liu. 1994. Unusual kinetics of uracil formation in single and double-stranded DNA by deamination of cytosine in cyclobutane pyrimidine dimers. J. Mol. Biol. 235:807–812.
   PubMedGoogle Scholar
• Tessman, I., S.-K. Liu, and M. A. Kennedy. 1992. Mechanism of SOS mutagenesis of UV-irradiated DNA: mostly error-free processing of deaminated cytosine. Proc. Natl. Acad. Sci. USA 89:1159–1163.
   PubMed Web of Science ®Google Scholar
• Washington, M. T., R. E. Johnson, S. Prakash, and L. Prakash. 2000. Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η. Proc. Natl. Acad. Sci. USA 97:3094–3099.
   PubMed Web of Science ®Google Scholar