Disruption of Ini1 Leads to Peri-Implantation Lethality and Tumorigenesis in Mice

REFERENCES

• Agalioti, T., S. Lomvardas, B. Parekh, J. Yie, T. Maniatis, and D. Thanos. 2000. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter. Cell 103:667–678.
   PubMed Web of Science ®Google Scholar
• Biegel, J. A., J. Y. Zhou, L. B. Rorke, C. Stenstrom, L. M. Wainwright, and B. Fogelgren. 1999. Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors. Cancer Res. 59:74–79.
   PubMed Web of Science ®Google Scholar
• Bochar, D. A., L. Wang, H. Beniya, A. Kinev, Y. Xue, W. S. Lane, W. Wang, F. Kashanchi, and R. Shiekhattar. 2000. BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell 102:257–265.
   PubMed Web of Science ®Google Scholar
• Breeden, L., and K. Nasmyth. 1987. Cell cycle control of the yeast HO gene: cis- and trans-acting regulators. Cell 48:389–397.
   PubMedGoogle Scholar
• Bruder, C. E., J. P. Dumanski, and D. Kedra. 1999. The mouse ortholog of the human SMARCB1 gene encodes two splice forms. Biochem. Biophys. Res. Commun. 257:886–890.
   PubMedGoogle Scholar
• Cairns, B. R., Y.-J. Kim, M. H. Sayre, B. C. Laurent, and R. D. Kornberg. 1994. A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast. Proc. Natl. Acad. Sci. USA 91:1950–1954.
   PubMed Web of Science ®Google Scholar
• Chiba, H., M. Muramatsu, A. Nomoto, and H. Kato. 1994. Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila Brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res. 22:1815–1820.
   PubMed Web of Science ®Google Scholar
• Côté, J., J. Quinn, J. L. Workman, and C. L. Peterson. 1994. Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science 265:53–60.
   PubMed Web of Science ®Google Scholar
• DeCristofaro, M. F., B. L. Betz, W. Wang, and B. E. Weissman. 1999. Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors. Oncogene 18:7559–7565.
   PubMed Web of Science ®Google Scholar
• de la Serna, I. L., K. A. Carlson, D. A. Hill, C. J. Guidi, R. O. Stephenson, S. Sif, R. E. Kingston, and A. N. Imbalzano. 2000. Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene. Mol. Cell. Biol. 20:2839–2851.
   PubMedGoogle Scholar
• Dunaief, J. L., B. E. Strober, S. Guha, P. A. Khavari, K. Ålin, J. Luban, M. Begemann, G. R. Crabtree, and S. P. Goff. 1994. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 79:119–130.
   PubMed Web of Science ®Google Scholar
• Francis-West, P., R. Ladher, A. Barlow, and A. Graveson. 1998. Signalling interactions during facial development. Mech. Dev. 75:3–28.
   PubMedGoogle Scholar
• Fryer, C. J., and T. K. Archer. 1998. Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex. Nature 393:88–91.
   PubMed Web of Science ®Google Scholar
• Harvey, M., M. J. McArthur, C. A. Montgomery Jr., J. S. Butel, A. Bradley, and L. A. Donehower. 1993. Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice. Nat. Genet. 5:225–229.
   PubMed Web of Science ®Google Scholar
• Hirschhorn, J. N., S. A. Brown, C. D. Clark, and F. Winston. 1992. Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure. Genes Dev. 6:2288–2298.
   PubMed Web of Science ®Google Scholar
• Imbalzano, A.. 1998. ATP dependent chromatin remodelers: complex complexes and their components. Crit. Rev. Eukaryot. Gene Expr. 8:225–255.
   PubMedGoogle Scholar
• Imbalzano, A. N., H. Kwon, M. R. Green, and R. E. Kingston. 1994. Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature 370:481–485.
   PubMed Web of Science ®Google Scholar
• Kalpana, G. V., S. Marmon, W. Wang, G. R. Crabtree, and S. P. Goff. 1994. Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science 266:2002–2006.
   PubMed Web of Science ®Google Scholar
• Khavari, P. A., C. L. Peterson, J. W. Tamkun, and G. R. Crabtree. 1993. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature 366:170–174.
   PubMed Web of Science ®Google Scholar
• Kingston, R., and G. Narlikar. 1999. ATP dependent remodeling and acetylation as regulators of chromatin fluidity. Genes Dev. 13:2339–2352.
   PubMed Web of Science ®Google Scholar
• Klochendler-Yeivin, A., L. Fiette, J. Barra, C. Muchardt, C. Babinet, and M. Yaniv. 2000. The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep. 1:500–506.
   PubMed Web of Science ®Google Scholar
• Kodaki, T., K. Hosaka, J. Nikawa, and S. Yamashita. 1995. The SNF2/SWI2/GAM1/TYE3/RIC1 gene is involved in the coordinate regulation of phospholipid synthesis in Saccharomyces cerevisiae. J. Biochem. (Tokyo) 117:362–368.
   PubMedGoogle Scholar
• Kruger, W., and I. Herskowitz. 1991. A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA binding protein related to HMG1. Mol. Cell. Biol. 11:4135–4146.
   PubMed Web of Science ®Google Scholar
• Kruger, W., C. L. Peterson, A. Sil, C. Coburn, G. Arents, E. N. Moudrianakis, and I. Herskowitz. 1995. Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription. Genes Dev. 9:2770–2779.
   PubMed Web of Science ®Google Scholar
• Kwon, H., A. N. Imbalzano, P. A. Khavari, R. E. Kingston, and M. R. Green. 1994. Nucleosome disruption and enhancement of activator binding by a human SWI/SNF complex. Nature 370:477–481.
   PubMed Web of Science ®Google Scholar
• Laurent, B. C., I. Treich, and M. Carlson. 1993. The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation. Genes Dev. 7:583–591.
   PubMedGoogle Scholar
• Lee, D., H. Sohn, G. V. Kalpana, and J. Choe. 1999. Interaction of E1 and hSNF5 proteins stimulates replication of human papillomavirus DNA. Nature 399:487–491.
   PubMedGoogle Scholar
• Miller, M. E., B. R. Cairns, R. S. Levinson, K. R. Yamamoto, D. A. Engel, and M. M. Smith. 1996. Adenovirus E1A specifically blocks SWI/SNF-dependent transcriptional activation. Mol. Cell. Biol. 16:5737–5743.
   PubMedGoogle Scholar
• Muchardt, C., C. Sardet, B. Bourachot, C. Onufryk, and M. Yaniv. 1995. A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm. Nucleic Acids Res. 23:1127–1132.
   PubMedGoogle Scholar
• Muchardt, C., and M. Yaniv. 1993. A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. EMBO J. 12:4279–4290.
   PubMed Web of Science ®Google Scholar
• Murphy, D. J., S. Hardy, and D. A. Engel. 1999. Human SWI-SNF component BRG1 represses transcription of the c-fos gene. Mol. Cell. Biol. 19:2724–2733.
   PubMedGoogle Scholar
• Neigeborn, L., and M. Carlson. 1984. Genes affecting the regulation of SUC2 gene expression by glucose repression in saccharomyces cerevisiae. Genetics 108:845–858.
   PubMed Web of Science ®Google Scholar
• Peterson, C. L., A. Dingwall, and M. P. Scott. 1994. Five SWI/SNF gene products are components of a large multiprotein complex required for transcriptional enhancement. Proc. Natl. Acad. Sci. USA 91:2905–2908.
   PubMed Web of Science ®Google Scholar
• Peterson, L., and I. Herskowitz. 1992. Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription. Cell 68:573–583.
   PubMed Web of Science ®Google Scholar
• Reyes, J. C., J. Barra, C. Muchardt, A. Camus, C. Babinet, and M. Yaniv. 1998. Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha). EMBO J. 17:6979–6991.
   PubMed Web of Science ®Google Scholar
• Roberts, C. W. M., S. A. Galusha, M. E. McMenamin, C. D. M. Fletcher, and S. H. Orkin. 2000. Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice. Proc. Natl. Acad. Sci. USA 97:13796–13800.
   PubMed Web of Science ®Google Scholar
• Rozenblatt-Rosen, O., T. Rozovskaia, D. Burakov, Y. Sedkov, S. Tillib, J. Blechman, T. Nakamura, C. M. Croce, A. Mazo, and E. Canaani. 1998. The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex. Proc. Natl. Acad. Sci. USA 95:4152–4157.
   PubMed Web of Science ®Google Scholar
• Schilling, T. F.. 1997. Genetic analysis of craniofacial development in the vertebrate embryo. Bioessays 19:459–468.
   PubMedGoogle Scholar
• Sévenet, N., A. Lellouch-Tubiana, D. Schofield, K. Hoang-Xuan, M. Gessler, D. Birnbaum, C. Jeanpierre, A. Jouvet, and O. Delattre. 1999. Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations. Hum. Mol. Genet. 8:2359–2368.
   PubMed Web of Science ®Google Scholar
• Sévenet, N., E. Sheridan, D. Amram, P. Schneider, R. Handgretinger, and O. Delattre. 1999. Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers. Am. J. Hum. Genet. 65:1342–1348.
   PubMed Web of Science ®Google Scholar
• Shanahan, F., W. Seghezzi, D. Parry, D. Mahony, and E. Lees. 1999. Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest. Mol. Cell. Biol. 19:1460–1469.
   PubMed Web of Science ®Google Scholar
• Stern, M. J., R. Jensen, and I. Herskowitz. 1984. Five SWI genes are required for expression of the HO gene in yeast. J. Mol. Biol. 178:853–868.
   PubMed Web of Science ®Google Scholar
• Sterner, D. E., and S. L. Berger. 2000. Acetylation of histones and transcription-related factors. Microbiol. Mol. Biol. Rev. 64:435–459.
   PubMed Web of Science ®Google Scholar
• Strahl, B. D., and C. D. Allis. 2000. The language of covalent histone modifications. Nature 403:41–45.
   PubMed Web of Science ®Google Scholar
• Strobeck, M. W., K. E. Knudsen, A. F. Fribourg, M. F. DeCristoforo, B. E. Weissman, A. N. Imbalzano, and E. S. Knudsen. 2000. BRG-1 is required for Rb-mediated cell cycle arrest. Proc. Natl. Acad. Sci. USA 97:7748–7753.
   PubMed Web of Science ®Google Scholar
• Sumi-Ichinose, C., H. Ichinose, D. Metzger, and P. Chambon. 1997. SNF2β-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells. Mol. Cell. Biol. 17:5976–5986.
   PubMed Web of Science ®Google Scholar
• Takai, H., K. Tominaga, N. Motoyama, Y. A. Minamishima, H. Nagahama, T. Tsukiyama, K. Ikeda, K. Nakayama, M. Nakanishi, and K.-I. Nakayama. 2000. Aberrant cell cycle checkpoint function and early embryonic death in Chk1−/− mice. Genes Dev. 14:1439–1447.
   PubMed Web of Science ®Google Scholar
• Trouche, D., C. Le Chalony, C. Muchardt, M. Yaniv, and T. Kouzarides. 1997. Rb and hbrm cooperate to repress the activation functions of E2F1. Proc. Natl. Acad. Sci. USA 94:11268–11273.
   PubMed Web of Science ®Google Scholar
• Versteege, I., N. Sevenet, J. Lange, M. F. Rousseau-Merck, P. Ambros, R. Handgretinger, A. Aurias, and O. Delattre. 1998. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394:203–206.
   PubMed Web of Science ®Google Scholar
• Vignali, M., A. H. Hassan, K. E. Neely, and J. L. Workman. 2000. ATP-dependent chromatin-remodeling complexes. Mol. Cell. Biol. 20:1899–1910.
   PubMed Web of Science ®Google Scholar
• Wang, W., Y. Xue, S. Zhou, A. Kuo, B. R. Cairns, and G. R. Crabtree. 1996. Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev. 10:2117–2130.
   PubMed Web of Science ®Google Scholar
• Wong, A. K., F. Shanahan, Y. Chen, L. Lian, P. Ha, K. Hendricks, S. Ghaffari, D. Iliev, B. Penn, A. M. Woodland, R. Smith, G. Salada, A. Carillo, K. Laity, J. Gupte, B. Swedlund, S. V. Tavtigian, D. H. Teng, and E. Lees. 2000. BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res. 60:6171–6177.
   PubMed Web of Science ®Google Scholar
• Wu, D. Y., G. V. Kalpana, S. P. Goff, and W. H. Schubach. 1996. Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Ini1. J. Virol. 70:6020–6028.
   PubMedGoogle Scholar
• Yoshimoto, H., and I. Yamashita. 1991. The GAM1/SNF2 gene of Saccharomyces cerevisiae encodes a highly charged nuclear protein required for transcription of the STA1 gene. Mol. Gen. Genet. 228:270–280.
   PubMedGoogle Scholar
• Zambrowicz, B., G. Friedrich, E. Buxton, S. Lilleberg, C. Person, and A. Sands. 1998. Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature 392:608–611.
   PubMed Web of Science ®Google Scholar
• Zhang, H. S., M. Gavin, A. Dahiya, A. A. Postigo, D. Ma, R. X. Luo, J. W. Harbour, and D. C. Dean. 2000. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell 101:79–89.
   PubMed Web of Science ®Google Scholar