11
Views
40
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Cyclin A Is a Mediator of p120E4F-Dependent Cell Cycle Arrest in G1

, , , , , , & show all
Pages 2956-2966 | Received 31 Jul 2000, Accepted 03 Jan 2001, Published online: 28 Mar 2023

REFERENCES

  • Barlat, I., D. Fesquet, C. Brechot, B. Henglein, A. Dupuy d'Angeac, A. Vie, and J. M. Blanchard. 1993. Loss of the G1-S control of cyclin A expression during tumoral progression of Chinese hamster lung fibroblasts. Cell Growth Differ. 4:105–113.
  • Barlat, I., B. Henglein, A. Plet, N. Lamb, A. Fernandez, F. McKenzie, J. Pouyssegur, A. Vie, and J. M. Blanchard. 1995. TGF-beta 1 and cAMP attenuate cyclin A gene transcription via a cAMP responsive element through independent pathways. Oncogene 11:1309–1318.
  • Brugarolas, J., C. Chandrasekaran, J. I. Gordon, D. Beach, T. Jacks, and G. J. Hannon. 1995. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552–557.
  • Chambard, J. C., and P. Pognonec. 1998. A reliable way of obtaining stable inducible clones. Nucleic Acids Res. 26:3443–3444.
  • Chin, J. W., J. J. Kohler, T. L. Schneider, and A. Schepartz. 1999. Protein escorts to the transcription ball. Curr. Biol. 9:R929–R932.
  • Cowley, D. O., and B. J. Graves. 2000. Phosphorylation represses ets-1 DNA binding by reinforcing autoinhibition. Genes Dev. 14:366–376.
  • Desdouets, C., G. Matesic, C. A. Molina, N. S. Foulkes, P. Sassone-Corsi, C. Brechot, and J. Sobczak-Thepot. 1995. Cell cycle regulation of cyclin A gene expression by the cyclic AMP-responsive transcription factors CREB and CREM. Mol. Cell. Biol. 15:3301–3309.
  • Donehower, L. A., M. Harvey, B. L. Slagle, M. J. McArthur, C. A. Montgomery Jr., J. S. Butel, and A. Bradley. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215–221.
  • Du, W., and T. Maniatis. 1994. The high mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF-2 isoforms. Proc. Natl. Acad. Sci. USA 91:11318–11322.
  • Fajas, L., C. Paul, O. Zugasti, L. Le Cam, J. Polanowska, E. Fabbrizio, R. Medema, M. L. Vignais, and C. Sardet. 2000. pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F. Proc. Natl. Acad. Sci. USA 97:7738–7743.
  • Fernandes, E. R., and R. J. Rooney. 1997. The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor φAP3. Mol. Cell. Biol. 17:1890–1903.
  • Fernandes, E. R., J. Y. Zhang, and R. J. Rooney. 1998. Adenovirus E1A-regulated transcription factor p120E4F inhibits cell growth and induces the stabilization of the cdk inhibitor p21WAF1. Mol. Cell. Biol. 18:459–467.
  • Fognani, C., G. Della Valle, and L. E. Babiss. 1993. Repression of adenovirus E1A enhancer activity by a novel zinc finger-containing DNA-binding protein related to the GLI-Kruppel protein. EMBO J. 12:4985–4992.
  • Giaccia, A. J., and M. B. Kastan. 1998. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12:2973–83.
  • Girard, F., U. Strausfeld, A. Fernandez, and N. J. Lamb. 1991. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67:1169–1179.
  • Hamel, P. A., R. M. Gill, R. A. Phillips, and B. L. Gallie. 1992. Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene. Mol. Cell. Biol. 12:3431–3438.
  • Harvey, D. M., and A. J. Levine. 1991. p53 alternation is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev 5:2375–2385.
  • Heichman, K. A., and J. M. Roberts. 1994. Rules to replicate by. Cell 79:557–562.
  • Hinds, P. W., S. Mittnacht, V. Dulic, A. Arnold, S. I. Reed, and R. A. Weinberg. 1992. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70:993–1006.
  • Hua, X. H., H. Yan, and J. Newport. 1997. A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle. J. Cell Biol. 137:183–192.
  • Huet, X., J. Rech, A. Plet, A. Vie, and J. M. Blanchard. 1996. Cyclin A expression is under negative transcriptional control during the cell cycle. Mol. Cell. Biol. 16:3789–3798.
  • Iordanov, M., K. Bender, T. Ade, W. Schmid, C. Sachsenmaier, K. Engel, M. Gaestel, H. J. Rahmsdorf, and P. Herrlich. 1997. CREB is activated by UVC through a p38/HOG-1-dependent protein kinase. EMBO J. 16:1009–1022.
  • Jones, C., and K. A. Lee. 1991. E1A-mediated activation of the adenovirus E4 promoter can occur independently of the cellular transcription factor E4F. Mol. Cell. Biol. 11:4297–4305.
  • Kingsley-Kallesen, M. L., D. Kelly, and A. Rizzino. 1999. Transcriptional regulation of the transforming growth factor-beta2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein. J. Biol. Chem. 274:34020–34028.
  • Kobayashi, M., A. Shimomura, M. Hagiwara, and K. Kawakami. 1997. Phosphorylation of ATF-1 enhances its DNA binding and transcription of the Na,K-ATPase alpha 1 subunit gene promoter. Nucleic Acids Res. 25:877–882.
  • Krude, T., M. Jackman, J. Pines, and R. A. Laskey. 1997. Cyclin/Cdk-dependent initiation of DNA replication in a human cell-free system. Cell 88:109–119.
  • Medema, R. H., R. E. Herrera, F. Lam, and R. A. Weinberg. 1995. Growth suppression by p16ink4 requires functional retinoblastoma protein. Proc. Natl. Acad. Sci. USA 92:6289–6293.
  • Oren, M.. 1999. Regulation of the p53 tumor suppressor protein. J. Biol. Chem. 274:36031–36034.
  • Pagano, M., R. Pepperkok, F. Verde, W. Ansorge, and G. Draetta. 1992. Cyclin A is required at two points in the human cell cycle. EMBO J. 11:961–971.
  • Philips, A., S. Chambeyron, N. Lamb, A. Vie, and J. M. Blanchard. 1999. CHF: a novel factor binding to cyclin A CHR corepressor element. Oncogene 18:6222–6232.
  • Philips, A., X. Huet, A. Plet, L. Le Cam, A. Vie, and J. M. Blanchard. 1998. The retinoblastoma protein is essential for cyclin A repression in quiescent cells. Oncogene 16:1373–1381.
  • Philips, A., X. Huet, A. Plet, J. Rech, A. Vie, and J. M. Blanchard. 1999. Anchorage-dependent expression of cyclin A in primary cells requires a negative DNA regulatory element and a functional Rb. Oncogene 18:1819–1825.
  • Plet, A., X. Huet, M. Algarte, J. Rech, J. Imbert, A. Philips, and J. M. Blanchard. 1997. Relief of cyclin A gene transcriptional inhibition during activation of human primary T lymphocytes via CD2 and CD28 adhesion molecules. Oncogene 14:2575–2583.
  • Raychaudhuri, P., S. Bagchi, and J. R. Nevins. 1989. DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation. Genes Dev. 3:620–627.
  • Raychaudhuri, P., R. Rooney, and J. R. Nevins. 1987. Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter. EMBO J. 6:4073–4081.
  • Rooney, R. J., R. R. Daniels, N. A. Jenkins, D. J. Gilbert, K. Rothammer, S. W. Morris, D. R. Higgs, and N. G. Copeland. 1998. Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice. Mamm. Genome 9:320–323.
  • Rooney, R. J., P. Raychaudhuri, and J. R. Nevins. 1990. E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activation. Mol. Cell. Biol. 10:5138–5149.
  • Rooney, R. J., K. Rothammer, and E. R. Fernandes. 1998. Mutational analysis of p50E4F suggests that DNA binding activity is mediated through an alternative structure in a zinc finger domain that is regulated by phosphorylation. Nucleic Acids Res. 26:1681–1688.
  • Sandy, P., M. Gostissa, V. Fogal, L. D. Cecco, K. Szalay, R. J. Rooney, C. Schneider, and G. D. Sal. 2000. p53 is involved in the p120E4F-mediated growth arrest. Oncogene 19:188–199.
  • Sardet, C., L. LeCam, E. Fabrizio, and M. Vidal. 1997. E2Fs and the retinoblastoma protein family. Progress in gene expression/oncogenes as transcriptional regulators. J. Ghysdael, and M. Yaniv. 2. Cell cycle and chromosomal translocation:1–62. Birkhäuser Verlag, Basel, Switzerland
  • Shaywitz, A. J., and M. E. Greenberg. 1999. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu. Rev. Biochem. 68:821–861.
  • Sherr, C. J.. 1996. Cancer cell cycles. Science 274:1672–1677.
  • Strausfeld, U. P., M. Howell, R. Rempel, J. L. Maller, T. Hunt, and J. J. Blow. 1994. Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Curr. Biol. 4:876–883.
  • Virbasius, C. M., S. Wagner, and M. R. Green. 1999. A human nuclear-localized chaperone that regulates dimerization, DNA binding, and transcriptional activity of bZIP proteins. Mol. Cell 4:219–228.
  • Zindy, F., E. Lamas, X. Chenivesse, J. Sobczak, J. Wang, D. Fesquet, B. Henglein, and C. Brechot. 1992. Cyclin A is required in S phase in normal epithelial cells. Biochem. Biophys. Res. Commun. 182:1144–1154.
  • Zwicker, J., F. C. Lucibello, L. A. Wolfraim, C. Gross, M. Truss, K. Engeland, and R. Muller. 1995. Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression. EMBO J. 14:4514–4522.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.