Characterization of Specific Protein-RNA Complexes Associated with the Coupling of Polyadenylation and Last-Intron Removal

REFERENCES

• Bagga, P. S., G. K. Arhin, and J. Wilusz. 1998. DSEF-1 is a member of the hnRNP H family of RNA-binding proteins and stimulates pre-mRNA cleavage and polyadenylation in vitro. Nucleic Acids Res. 26: 5343–5350.
   PubMed Web of Science ®Google Scholar
• Bagga, P. S., L. P. Ford, F. Chen, and J. Wilusz. 1995. The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3′ end pre-mRNA processing through a trans-factor. Nucleic Acids Res. 23: 1625–1631.
   PubMed Web of Science ®Google Scholar
• Berger, S. L., and W. R. Folk. 1985. Differential activation of RNA polymerase III-transcribed genes by the polyoma virus enhancer and adenovirus E1A gene products. Nucleic Acids Res. 13: 1413–1428.
   PubMed Web of Science ®Google Scholar
• Berget, S. M. 1995. Exon recognition in vertebrate splicing. J. Biol. Chem. 270: 2411–2414.
   PubMed Web of Science ®Google Scholar
• Brackenridge, S., H. L. Ashe, M. Giacca, and N. J. Proudfoot. 1997. Transcription and polyadenylation in a short human intergenic region. Nucleic Acids Res. 25: 2326–2335.
   PubMedGoogle Scholar
• Brown, P. H., L. S. Tiley, and B. R. Cullen. 1991. Efficient polyadenylation with the human immunodeficiency virus type 1 long terminal repeat requires flanking U3-specific sequences. J. Virol. 65: 3340–3343.
   PubMed Web of Science ®Google Scholar
• Carswell, S., and J. C. Alwine. 1989. Efficiency of utilization of the simian virus 40 late polyadenylation site: effects of upstream sequences. Mol. Cell. Biol. 9: 4248–4258.
   PubMed Web of Science ®Google Scholar
• Chiou, H. C., C. Dabrowski, and J. C. Alwine. 1991. Simian virus 40 late mRNA leader sequence involved in augmenting mRNA accumulation via multiple mechanisms, including increased polyadenylation efficiency. J. Virol. 65: 6677–6685.
   PubMedGoogle Scholar
• Conway, L., and M. Wickens. 1985. A sequence downstream of AAUAAA is required for formation of simian virus 40 late mRNA 3′ termini in frog oocytes. Proc. Natl. Acad. Sci. USA 82: 3949–3953.
   PubMedGoogle Scholar
• Cooke, C., and J. C. Alwine. 1996. The cap and 3′-splice site similarly affect polyadenylation efficiency. Mol. Cell. Biol. 16: 2579–2584.
   PubMedGoogle Scholar
• Cooke, C., H. Hans, and J. C. Alwine. 1999. Utilization of splicing elements and polyadenylation signal elements in the coupling of splicing and last-intron removal. Mol. Cell. Biol. 19: 4971–4979.
   PubMedGoogle Scholar
• DeZazzo, J. D., and M. J. Imperiale. 1989. Sequences upstream of AAUAAA influence poly(A) site selection in a complex transcription unit. Mol. Cell. Biol. 9: 4951–4961.
   PubMed Web of Science ®Google Scholar
• DeZazzo, J. D., J. E. Kilpatrick, and M. J. Imperiale. 1991. Involvement of long terminal repeat U3 sequences overlapping the transcription control region in human immunodeficiency virus type I mRNA 3′ end formation. Mol. Cell. Biol. 11: 1624–1630.
   PubMed Web of Science ®Google Scholar
• Hans, H., and J. C. Alwine. 2000. Functionally significant secondary structure of the simian virus 40 late polyadenylation signal. Mol. Cell. Biol. 20: 2926–2932.
   PubMedGoogle Scholar
• Hong, W., M. Bennett, Y. Xiao, R. Feld-Kramer, C. Wang, and R. Reed. 1997. Association of U2 snRNP with the spliceosomal complex E. Nucleic Acids Res. 25: 354–361.
   PubMedGoogle Scholar
• Izaurralde, E., J. Lewis, C. McGuigan, M. Jankowska, E. Darzynkiewicz, and I. W. Mattaj. 1994. A nuclear cap binding complex involved in pre-mRNA splicing. Cell 78: 657–668.
   PubMed Web of Science ®Google Scholar
• Lewis, J. D., E. Izaurralde, A. Jarmolowski, C. McGuigan, and I. W. Mattaj. 1996. A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5′ splice site. Genes Dev. 10: 1683–1698.
   PubMed Web of Science ®Google Scholar
• Lutz, C. S., K. G. Murthy, N. Schek, J. L. Manley, and J. C. Alwine. 1996. Interaction between the U1snRNP-A protein and the 160 kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes Dev. 10: 325–337.
   PubMed Web of Science ®Google Scholar
• Moore, C. L., and P. A. Sharp. 1984. Site-specific polyadenylation in a cell-free reaction. Cell 36: 581–591.
   PubMedGoogle Scholar
• Moreira, A., M. Wollerton, J. Monks, and N. J. Proudfoot. 1995. Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved. EMBO J. 14: 3809–3819.
   PubMed Web of Science ®Google Scholar
• Nesic, D., J. Cheng, and L. E. Maquat. 1993. Sequences within the last intron function in RNA 3′-end formation in cultured cells. Mol. Cell. Biol. 13: 3359–3369.
   PubMed Web of Science ®Google Scholar
• Nesic, D., and L. E. Maquat. 1994. Upstream introns influence the efficiency of final intron removal and RNA 3′-end formation. Genes Dev. 8: 363–375.
   PubMedGoogle Scholar
• Niwa, M., and S. M. Berget. 1991. Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns. Genes Dev. 5: 2086–2095.
   PubMedGoogle Scholar
• Niwa, M., and S. M. Berget. 1991. Polyadenylation precedes splicing in vitro. Gene Expr. 1: 5–14.
   PubMedGoogle Scholar
• Niwa, M., C. C. MacDonald, and S. M. Berget. 1990. Are vertebrate exons scanned during splice site selection? Nature (London) 360: 277–280.
   Google Scholar
• Niwa, M., S. D. Rose, and S. M. Berget. 1990. In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev. 4: 1552–1559.
   PubMed Web of Science ®Google Scholar
• Qian, Z., and J. Wilusz. 1991. An RNA-binding protein specifically interacts with a functionally important domain of the downstream element of the simian virus 40 late polyadenylation signal. Mol. Cell. Biol. 11: 5312–5320.
   PubMedGoogle Scholar
• Reed, R. 2000. Mechanisms of fidelity in pre-mRNA splicing. Curr. Opin. Cell Biol. 12: 340–345.
   PubMed Web of Science ®Google Scholar
• Robberson, B. L., G. J. Cote, and S. M. Berget. 1990. Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol. Cell. Biol. 10: 84–94.
   PubMed Web of Science ®Google Scholar
• Russnak, R. 1991. Regulation of polyadenylation in hepatitis B viruses: stimulation by the upstream activating signal PS1 is orientation-dependent, distance-dependent, and additive. Nucleic Acids Res. 19: 6449–6456.
   PubMedGoogle Scholar
• Russnak, R., and D. Ganem. 1990. Sequences 5′ to the polyadenylation signal mediate differential poly(A) site use in hepatitis B viruses. Genes Dev. 4: 764–776.
   PubMedGoogle Scholar
• Sadofsky, M., and J. C. Alwine. 1984. Sequences on the 3′ side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site. Mol. Cell. Biol. 4: 1460–1468.
   PubMedGoogle Scholar
• Sadofsky, M., S. Connelly, J. L. Manley, and J. C. Alwine. 1985. Identification of a sequence element on the 3′ side of AAUAAA which is necessary for simian virus 40 late mRNA 3′-end processing. Mol. Cell. Biol. 5: 2713–2719.
   PubMedGoogle Scholar
• Sanfacon, H., P. Brodmann, and T. Hohn. 1991. A dissection of the cauliflower mosaic virus polyadenylation signal. Genes Dev. 5: 141–149.
   PubMed Web of Science ®Google Scholar
• Schek, N., C. Cooke, and J. C. Alwine. 1992. Definition of the upstream efficiency element of the simian virus 40 late polyadenylation signal by using in vitro analyses. Mol. Cell. Biol. 12: 5386–5393.
   PubMed Web of Science ®Google Scholar
• Scott, J. M., and M. J. Imperiale. 1996. Reciprocal effects of splicing and polyadenylation on human immunodeficiency virus type 1 pre-mRNA processing. Virology 224: 498–509.
   PubMed Web of Science ®Google Scholar
• Staknis, D., and R. Reed. 1994. SR proteins promote the first specific recognition of pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex. Mol. Cell. Biol. 14: 7670–7682.
   PubMed Web of Science ®Google Scholar
• Takagaki, Y., and J. L. Manley. 1997. RNA recognition by the human polyadenylation factor CstF. Mol. Cell. Biol. 17: 3907–3914.
   PubMedGoogle Scholar
• Tsai, T. F., M. J. Wu, and T. S. Su. 1998. Usage of cryptic splice sites in citrullinemia fibroblasts suggests role of polyadenylation in splice-site selection during terminal exon definition. DNA Cell Biol. 17: 717–725.
   PubMedGoogle Scholar
• Vagner, S., C. Vagner, and I. W. Mattaj. 2000. The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3′-end processing and splicing. Genes Dev. 14: 403–413.
   PubMed Web of Science ®Google Scholar
• Valsamakis, A., N. Schek, and J. C. Alwine. 1992. Elements upstream of the AAUAAA within the human immunodeficiency virus polyadenylation signal are required for efficient polyadenylation in vitro. Mol. Cell. Biol. 12: 3699–3705.
   PubMed Web of Science ®Google Scholar
• Valsamakis, A., S. Zeichner, S. Carswell, and J. C. Alwine. 1991. The human immunodeficiency virus type 1 polyadenylation signal: a 3′-LTR element upstream of the AAUAAA necessary for efficient polyadenylation. Proc. Natl. Acad. Sci. USA 88: 2108–2112.
   PubMed Web of Science ®Google Scholar
• Wilusz, J., D. I. Feig, and T. Shenk. 1988. The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites. Mol. Cell. Biol. 8: 4477–4483.
   PubMedGoogle Scholar
• Wilusz, J., and T. Shenk. 1990. A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal. Mol. Cell. Biol. 10: 6397–6407.
   PubMed Web of Science ®Google Scholar