Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell Morphology

REFERENCES

• Allen, P. B., C. C. Ouimet, and P. Greengard. 1997. Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc. Natl. Acad. Sci. USA 94: 9956–9961.
   PubMed Web of Science ®Google Scholar
• Beavo, J. A., P. J. Bechtel, and E. G. Krebs. 1974. Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle. Methods Enzymol. 38: 299–308.
   PubMedGoogle Scholar
• Blitzer, R. D., J. H. Connor, G. P. Brown, T. Wong, S. Shenolikar, R. Iyengar, and E. M. Landau. 1998. Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. Science 280: 1940–1942.
   PubMedGoogle Scholar
• Burnett, P. E., S. Blackshaw, M. M. Lai, I. A. Qureshi, A. F. Burnett, D. M. Sabatini, and S. H. Snyder. 1998. Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton. Proc. Natl. Acad. Sci. USA 95: 8351–8356.
   PubMed Web of Science ®Google Scholar
• Cohen, P., C. F. Holmes, and Y. Tsukitani. 1990. Okadaic acid: a new probe for the study of cellular regulation. Trends Biochem. Sci. 15: 98–102.
   PubMed Web of Science ®Google Scholar
• Connor, J. H., D. C. Weiser, S. Li, J. M. Hallenbeck, and S. Shenolikar. 2001. Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1. Mol. Cell. Biol. 21: 6841–6850.
   PubMedGoogle Scholar
• Dent, P., D. G. Campbell, F. B. Caudwell, and P. Cohen. 1990. Identification of three in vivo phosphorylation sites on the glycogen-binding subunit of protein phosphatase 1 from rabbit skeletal muscle, and their response to adrenaline. FEBS Lett. 259: 281–285.
   PubMed Web of Science ®Google Scholar
• Durfee, T., K. Becherer, P. L. Chen, S. H. Yeh, Y. Yang, A. E. Kilburn, W. H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7: 555–569.
   PubMed Web of Science ®Google Scholar
• Feng, J., Z. Yan, A. Ferreira, K. Tomizawa, J. A. Liauw, M. Zhuo, P. B. Allen, C. C. Ouimet, and P. Greengard. 2000. Spinophilin regulates the formation and function of dendritic spines. Proc. Natl. Acad. Sci. USA 97: 9287–9292.
   PubMed Web of Science ®Google Scholar
• Helps, N. R., X. Luo, H. M. Barker, and P. T. Cohen. 2000. NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1. Biochem. J. 349: 509–518.
   PubMed Web of Science ®Google Scholar
• Keegan, J., M. Schmerer, B. Ring, and D. Garza. 2001. The 62E early-late puff of Drosophila contains D-spinophilin, an ecdysone-inducible PDZ-domain protein dynamically expressed during metamorphosis. Genet. Res. 77: 27–39.
   PubMedGoogle Scholar
• Kimura, K., M. Ito, M. Amano, K. Chihara, Y. Fukata, M. Nakafuku, B. Yamamori, J. Feng, T. Nakano, K. Okawa, A. Iwamatsu, and K. Kaibuchi. 1996. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273: 245–248.
   PubMed Web of Science ®Google Scholar
• Liao, D., X. Zhang, R. O'Brien, M. D. Ehlers, and R. L. Huganir. 1999. Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons. Nat. Neurosci. 2: 37–43.
   PubMedGoogle Scholar
• Lupas, A. 1996. Coiled coils: new structures and new functions. Trends Biochem. Sci. 21: 375–382.
   PubMed Web of Science ®Google Scholar
• Luscher, C., R. A. Nicoll, R. C. Malenka, and D. Muller. 2000. Synaptic plasticity and dynamic modulation of the postsynaptic membrane. Nat. Neurosci. 3: 545–550.
   PubMed Web of Science ®Google Scholar
• MacMillan, L. B., M. A. Bass, N. Cheng, E. F. Howard, M. Tamura, S. Strack, B. E. Wadzinski, and R. J. Colbran. 1999. Brain actin-associated protein phosphatase 1 holoenzymes containing spinophilin, neurabin, and selected catalytic subunit isoforms. J. Biol. Chem. 274: 35845–35854.
   PubMedGoogle Scholar
• McAvoy, T., P. B. Allen, H. Obaishi, H. Nakanishi, Y. Takai, P. Greengard, A. C. Nairn, and H. C. Hemmings, Jr. 1999. Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation. Biochemistry 38: 12943–12949.
   PubMedGoogle Scholar
• Morishita, W., J. H. Connor, H. Xia, E. M. Quinlan, S. Shenolikar, and R. C. Malenka. 2001. Regulation of synaptic strength by protein phosphatase 1. Neuron 32: 1133–1148.
   PubMedGoogle Scholar
• Mulkey, R. M., S. Endo, S. Shenolikar, and R. C. Malenka. 1994. Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature 369: 486–488.
   PubMed Web of Science ®Google Scholar
• Nakanishi, H., H. Obaishi, A. Satoh, M. Wada, K. Mandai, K. Satoh, H. Nishioka, Y. Matsuura, A. Mizoguchi, and Y. Takai. 1997. Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formation. J. Cell Biol. 139: 951–961.
   PubMed Web of Science ®Google Scholar
• Nixon, J. B., and L. C. McPhail. 1999. Protein kinase C (PKC) isoforms translocate to Triton-insoluble fractions in stimulated human neutrophils: correlation of conventional PKC with activation of NADPH oxidase. J. Immunol. 163: 4574–4582.
   PubMed Web of Science ®Google Scholar
• Park, I. K., P. Roach, J. Bondor, S. P. Fox, and A. A. DePaoli-Roach. 1994. Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2. J. Biol. Chem. 269: 944–954.
   PubMedGoogle Scholar
• Parker, E. M., A. Monopoli, E. Ongini, G. Lozza, and C. M. Babij. 2000. Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression. Neuropharmacology 39: 1913–1919.
   PubMedGoogle Scholar
• Penzes, P., R. C. Johnson, R. Sattler, X. Zhang, R. L. Huganir, V. Kambampati, R. E. Mains, and B. A. Eipper. 2001. The neuronal Rho-GEF kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Neuron 29: 229–242.
   PubMed Web of Science ®Google Scholar
• Satoh, A., H. Nakanishi, H. Obaishi, M. Wada, K. Takahashi, K. Satoh, K. Hirao, H. Nishioka, Y. Hata, A. Mizoguchi, and Y. Takai. 1998. Neurabin-II/spinophilin. An actin filament-binding protein with one PDZ domain localized at cadherin-based cell-cell adhesion sites. J. Biol. Chem. 273: 3470–3475.
   PubMed Web of Science ®Google Scholar
• Shenolikar, S., and T. S. Ingebritsen. 1984. Protein (serine and threonine) phosphate phosphatases. Methods Enzymol. 107: 102–129.
   PubMedGoogle Scholar
• Stapleton, D., I. Balan, T. Pawson, and F. Sicheri. 1999. The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization. Nat. Struct. Biol. 6: 44–49.
   PubMedGoogle Scholar
• Stephens, D. J., and G. Banting. 1999. Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin. J. Biol. Chem. 274: 30080–30086.
   PubMedGoogle Scholar
• Stephens, D. J., and G. Banting. 2000. In vivo dynamics of the F-actin-binding protein neurabin-II. Biochem. J. 345: 185–194.
   PubMedGoogle Scholar
• Strack, S., M. A. Barban, B. E. Wadzinski, and R. J. Colbran. 1997. Differential inactivation of postsynaptic density-associated and soluble Ca2+/calmodulin-dependent protein kinase II by protein phosphatases 1 and 2A. J. Neurochem. 68: 2119–2128.
   PubMedGoogle Scholar
• Sugiyama, H., P. Papst, M. Fujita, E. W. Gelfand, and N. Terada. 1997. Overexpression of wild type p70 S6 kinase interferes with cytokinesis. Oncogene 15: 443–452.
   PubMedGoogle Scholar
• Terry-Lorenzo, R. T., M. Inoue, J. H. Connor, T. A. Haystead, B. N. Armbruster, R. P. Gupta, C. J. Oliver, and S. Shenolikar. 2000. Neurofilament-L is a protein phosphatase-1-binding protein associated with neuronal plasma membrane and post-synaptic density. J. Biol. Chem. 275: 2439–2446.
   PubMedGoogle Scholar
• Winder, D. G., and J. D. Sweatt. 2001. Roles of serine/threonine phosphatases in hippocampal synaptic plasticity. Nat. Rev. Neurosci. 2: 461–474.
   PubMed Web of Science ®Google Scholar
• Yan, Z., L. Hsieh-Wilson, J. Feng, K. Tomizawa, P. B. Allen, A. A. Fienberg, A. C. Nairn, and P. Greengard. 1999. Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin. Nat. Neurosci. 2: 13–17.
   PubMed Web of Science ®Google Scholar