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Transcriptional Regulation

Promoter Specificity and Biological Activity of Tethered AP-1 Dimers

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Pages 4952-4964 | Received 07 Mar 2002, Accepted 03 Apr 2002, Published online: 27 Mar 2023

REFERENCES

  • Amati, B., M. W. Brooks, N. Levy, T. D. Littlewood, G. I. Evan, and H. Land. 1993. Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell 72: 233–245.
  • Bakiri, L., D. Lallemand, E. Bossy-Wetzel, and M. Yaniv. 2000. Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression. EMBO J. 19: 2056–2068.
  • Bohmann, D., and R. Tjian. 1989. Biochemical analysis of transcriptional activation by Jun: differential activity of c- and v-Jun. Cell 59: 709–717.
  • Castellazzi, M., L. Loiseau, F. Piu, and A. Sergeant. 1993. Chimeric c-Jun containing an heterologous homodimerization domain transforms primary chick embryo fibroblasts. Oncogene 8: 1149–1160.
  • Chinenov, Y., and T. K. Kerppola. 2001. Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20: 2438–2452.
  • Chiu, R., P. Angel, and M. Karin. 1989. Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun. Cell 59: 979–986.
  • Desdouets, C., C. Ory, G. Matesic, T. Soussi, C. Brechot, and J. Sobczak-Thepot. 1996. ATF/CREB site mediated transcriptional activation and p53 dependent repression of the cyclin A promoter. FEBS Lett. 385: 34–38.
  • Eto, I. 2000. Molecular cloning and sequence analysis of the promoter region of mouse cyclin D1 gene: implication in phorbol ester-induced tumour promotion. Cell Prolif. 33: 167–187.
  • Evan, G. I., A. H. Wyllie, C. S. Gilbert, T. D. Littlewood, H. Land, M. Brooks, C. M. Waters, L. Z. Penn, and D. C. Hancock. 1992. Induction of apoptosis in fibroblasts by c-myc protein. Cell 69: 119–128.
  • Foletta, V. C. 1996. Transcription factor AP-1, and the role of Fra-2. Immunol. Cell Biol. 74: 121–133.
  • Glover, J. N., and S. C. Harrison. 1995. Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature 373: 257–261.
  • Grosset, C., C. Y. Chen, N. Xu, N. Sonenberg, H. Jacquemin-Sablon, and A. B. Shyu. 2000. A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex. Cell 103: 29–40.
  • Ham, J., C. Babij, J. Whitfield, C. M. Pfarr, D. Lallemand, M. Yaniv, and L. L. Rubin. 1995. A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14: 927–939.
  • Henglein, B., X. Chenivesse, J. Wang, D. Eick, and C. Brechot. 1994. Structure and cell cycle-regulated transcription of the human cyclin A gene. Proc. Natl. Acad. Sci. USA 91: 5490–5494.
  • Herber, B., M. Truss, M. Beato, and R. Müller. 1994. Inducible regulatory elements in the human cyclin D1 promoter. Oncogene 9: 1295–1304.
  • Hirai, S., B. Bourachot, and M. Yaniv. 1990. Both Jun and Fos contribute to transcription activation by the heterodimer. Oncogene 5: 39–46.
  • Jonat, C., B. Stein, H. Ponta, P. Herrlich, and H. J. Rahmsdorf. 1992. Positive and negative regulation of collagenase gene expression. Matrix Suppl. 1: 145–155.
  • Kolbus, A., I. Herr, M. Schreiber, K. M. Debatin, E. F. Wagner, and P. Angel. 2000. c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents. Mol. Cell. Biol. 20: 575–582.
  • Kovary, K., and R. Bravo. 1992. Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins. Mol. Cell. Biol. 12: 5015–5023.
  • Lallemand, D., G. Spyrou, M. Yaniv, and C. M. Pfarr. 1997. Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts. Oncogene 14: 819–830.
  • Landschulz, W. H., P. F. Johnson, and S. L. McKnight. 1988. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 240: 1759–1764.
  • Matsuo, K., J. M. Owens, M. Tonko, C. Elliott, T. J. Chambers, and E. F. Wagner. 2000. Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation. Nat. Genet. 24: 184–187.
  • Miller, A. D., T. Curran, and I. M. Verma. 1984. c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene. Cell 36: 51–60.
  • Morgenstern, J. P., and H. Land. 1990. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18: 3587–3596.
  • Neuhold, L. A., and B. Wold. 1993. HLH forced dimers: tethering MyoD to E47 generates a dominant positive myogenic factor insulated from negative regulation by Id. Cell 74: 1033–1042.
  • O'Shea, E. K., R. Rutkowski, and P. S. Kim. 1992. Mechanism of specificity in the Fos-Jun oncoprotein heterodimer. Cell 68: 699–708.
  • Passegué, E., and E. F. Wagner. 2000. JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression. EMBO J. 19: 2969–2979.
  • Pfarr, C. M., F. Mechta, G. Spyrou, D. Lallemand, S. Carillo, and M. Yaniv. 1994. Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. Cell 76: 747–760.
  • Philips, A., S. Chambeyron, N. Lamb, A. Vie, and J. M. Blanchard. 1999. CHF: a novel factor binding to cyclin A CHR corepressor element. Oncogene 18: 6222–6232.
  • Piette, J., S. Hirai, and M. Yaniv. 1988. Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts. Proc. Natl. Acad. Sci. USA 85: 3401–3405.
  • Pomerantz, J. L., P. A. Sharp, and C. O. Pabo. 1995. Structure-based design of transcription factors. Science 267: 93–96.
  • Schreiber, M., B. Baumann, M. Cotten, P. Angel, and E. F. Wagner. 1995. Fos is an essential component of the mammalian UV response. EMBO J. 14: 5338–5349.
  • Shaulian, E., and M. Karin. 2001. AP-1 in cell proliferation and survival. Oncogene 20: 2390–2400.
  • Sherr, C. J. 1996. Cancer cell cycles. Science 274: 1672–1677.
  • Sieber, M., and R. K. Allemann. 2000. Thermodynamics of DNA binding of MM17, a “single chain dimer” of transcription factor MASH-1. Nucleic Acids Res. 28: 2122–2127.
  • Tsurumi, C., N. Ishida, T. Tamura, A. Kakizuka, E. Nishida, E. Okumura, T. Kishimoto, M. Inagaki, K. Okazaki, and N. Sagata. 1995. Degradation of c-Fos by the 26S proteasome is accelerated by c-Jun and multiple protein kinases. Mol. Cell. Biol. 15: 5682–5687.
  • van Dam, H., S. Huguier, K. Kooistra, J. Baguet, E. Vial, A. J. van der Eb, P. Herrlich, P. Angel, and M. Castellazzi. 1998. Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation. Genes Dev. 12: 1227–1239.
  • van Dam, H., D. Wilhelm, I. Herr, A. Steffen, P. Herrlich, and P. Angel. 1995. ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J. 14: 1798–1811.
  • Weitzman, J. B., L. Fiette, K. Matsuo, and M. Yaniv. 2000. JunD protects cells from p53-dependent senescence and apoptosis. Mol. Cell 6: 1109–1119.
  • Wisdom, R., R. S. Johnson, and C. Moore. 1999. c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 18: 188–197.
  • Yoshizumi, M., C. M. Hsieh, F. Zhou, J. C. Tsai, C. Patterson, M. A. Perrella, and M. E. Lee. 1995. The ATF site mediates downregulation of the cyclin A gene during contact inhibition in vascular endothelial cells. Mol. Cell. Biol. 15: 3266–3272.

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