Transketolase Haploinsufficiency Reduces Adipose Tissue and Female Fertility in Mice

REFERENCES

• Bunger, L., M. Nicolson, and W. G. Hill. 1999. Leptin levels in lines of mice developed by long-term divergent selection on fat content. Genet. Res. 73: 37–44.
   PubMedGoogle Scholar
• Cascante, M., J. J. Centelles, R. L. Veech, W.-N. P. Lee, and L. G. Boros. 2000. Role of thiamin vitamin B-1 and transketolase in tumor cell proliferation. Nutr. Cancer 36: 150–154.
   PubMed Web of Science ®Google Scholar
• Coy, J. F., S. Dubel, P. Kioschis, K. Thomas, G. Micklem, H. Delius, and A. Poustka. 1996. Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes. Genomics 32: 309–316.
   PubMedGoogle Scholar
• Cuthbertson, R. A., S. I. Tomarev, and J. Piatigorsky. 1992. Taxon-specific recruitment of enzymes as major soluble proteins in the corneal epithelium of three mammals, chicken, and squid. Proc. Natl. Acad. Sci. USA 89: 4004–4008.
   PubMedGoogle Scholar
• Farooqi, I. S., J. M. Keogh, S. Kamath, S. Jones, W. T. Gibson, R. Trussell, S. A. Jebb, G. Y. Lip, and S. O'Rahilly. 2001. Partial leptin deficiency and adiposity. Nature 414: 34–35.
   PubMed Web of Science ®Google Scholar
• Guo, J., C. M. Sax, J. Piatigorsky, and F. X. Yu. 1997. Heterogeneous expression of transketolase in ocular tissues. Curr. Eye Res. 16: 467–474.
   PubMed Web of Science ®Google Scholar
• Havel, P. J. 2000. Role of adipose tissue in body-weight regulation: mechanisms regulating leptin production and energy balance. Proc. Nutr. Soc. 59: 359–371.
   PubMed Web of Science ®Google Scholar
• Henkes, S., U. Sonnewald, R. Badur, R. Flachmann, and M. Stitt. 2001. A small decrease of plastid transketolase activity in antisense tobacco transformants has dramatic effects on photosynthesis and phenylpropanoid metabolism. Plant Cell 13: 535–551.
   PubMed Web of Science ®Google Scholar
• Jester, J. V., T. Moller-Pedersen, J. Huang, C. M. Sax, W. T. Kays, H. D. Cavangh, W. M. Petroll, and J. Piatigorsky. 1999. The cellular basis of corneal transparency: evidence for “corneal crystallins.” J. Cell Sci. 112: 613–622.
   PubMed Web of Science ®Google Scholar
• Kather, H., M. Rivera, and K. Brand. 1972. Interrelationship and control of glucose metabolism and lipogenesis in isolated fat-cells. Effect of the amount of glucose uptake on the rates of the pentose phosphate cycle and of fatty acid synthesis. Biochem. J. 128: 1089–1096.
   PubMedGoogle Scholar
• Kochhar, H. P. S., J. Peippo, and W. A. King. 2001. Sex related embryo development. Theriogenology 55: 3–14.
   PubMed Web of Science ®Google Scholar
• Kril, J. J. 1996. Neuropathology of thiamine deficiency disorders. Metab. Brain Dis. 11: 9–17.
   PubMed Web of Science ®Google Scholar
• Martin, P. R., B. A. McCool, and C. K. Singleton. 1995. Molecular genetics of transketolase in the pathogenesis of the Wernicke-Korsakoff syndrome. Metab. Brain Dis. 10: 45–55.
   PubMedGoogle Scholar
• McCool, B. A., S. G. Plonk, P. R. Martin, and C. K. Singleton. 1993. Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals. J. Biol. Chem. 268: 1397–1404.
   PubMedGoogle Scholar
• Moitra, J., M. M. Mason, M. Olive, D. Krylov, O. Krylov, B. Marcus-Samuels, L. Feigenbaum, E. Lee, T. Aoyama, M. Eckhaus, M. L. Reitman, and C. Vinson. 1998. Life without white fat: a transgenic mouse. Genes Dev. 12: 3168–3181.
   PubMed Web of Science ®Google Scholar
• Nees, D. W., E. F. Wawrousek, W. G. Robison, Jr., and J. Piatigorsky. 2002. Structurally normal corneas in aldehyde dehydrogenase 3a1-deficient mice. Mol. Cell. Biol. 22: 849–855.
   PubMed Web of Science ®Google Scholar
• Nicol, C. J., J. Zielenski, L. C. Tsui, and P. G. Wells. 2000. An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis. FASEB J. 14: 111–127.
   PubMed Web of Science ®Google Scholar
• Paoletti, F. 1983. Purification and properties of transketolase from fresh rat liver. Arch. Biochem. Biophys. 222: 489–496.
   PubMedGoogle Scholar
• Paoletti, F., A. Mocali, and D. Tombaccini. 1997. Cysteine proteinases are responsible for characteristic transketolase alterations in Alzheimer fibroblasts. J. Cell Physiol. 172: 63–68.
   PubMedGoogle Scholar
• Peters, J., S. T. Ball, D. J. Charles, W. Pretsch, G. Bulfield, D. Miller, and V. M. Chapman. 1988. The localization of G6pd, glucose-6-phosphate dehydrogenase, and mdx, muscular dystrophy in the mouse X chromosome. Genet. Res. 52: 195–201.
   PubMedGoogle Scholar
• Piatigorsky, J. 1998. Gene sharing in lens and cornea: facts and implications. Prog. Retin. Eye Res. 17: 145–174.
   PubMed Web of Science ®Google Scholar
• Piatigorsky, J. 2001. Enigma of the abundant water-soluble cytoplasmic proteins of the cornea: the “refracton” hypothesis. Cornea 20: 853–858.
   PubMed Web of Science ®Google Scholar
• Reue, K., and M. Peterfy. 2000. Mouse models of lipodystrophy. Curr. Atheroscler. Rep. 2: 390–396.
   PubMedGoogle Scholar
• Salamon, C., M. Chervenak, J. Piatigorsky, and C. M. Sax. 1998. The mouse transketolase (TKT) gene: cloning, characterization, and functional promoter analysis. Genomics 48: 209–220.
   PubMedGoogle Scholar
• Sax, C. M., C. Salamon, W. T. Kays, J. Guo, F. X. Yu, R. A. Cuthbertson, and J. Piatigorsky. 1996. Transketolase is a major protein in the mouse cornea. J. Biol. Chem. 271: 33568–33574.
   PubMedGoogle Scholar
• Schenk, G., R. G. Duggleby, and P. F. Nixon. 1998. Properties and functions of the thiamin diphosphate dependent enzyme transketolase. Int. J. Biochem. Cell Biol. 30: 1297–1318.
   PubMedGoogle Scholar
• Schenk, G., R. Layfield, J. M. Candy, R. G. Duggleby, and P. F. Nixon. 1997. Molecular evolutionary analysis of the thiamine-diphosphate-dependent enzyme, transketolase. J. Mol. Evol. 44: 552–572.
   PubMed Web of Science ®Google Scholar
• Takeuchi, T., K. Nishino, and Y. Itokawa. 1984. Improved determination of transketolase activity in erythrocytes. Clin. Chem. 30: 658–661.
   PubMedGoogle Scholar
• Templeton, A. 2000. Infertility and the establishment of pregnancy—overview. Br. Med. Bull. 56: 577–587.
   PubMedGoogle Scholar
• Wang, P. J., J. R. McCarrey, F. Yang, and D. C. Page. 2001. An abundance of X-linked genes expressed in spermatogonia. Nat. Genet. 27: 422–426.
   PubMed Web of Science ®Google Scholar
• Wood, T. 1985. The pentose phosphate pathway. Academic Press/Harcourt Brace Jovanovich, New York, N.Y.
   Google Scholar