Transcriptional Repression of Peri-Implantation EMX2 Expression in Mammalian Reproduction by HOXA10

REFERENCES

• Akam, M. 1989. Hox and HOM: homologous gene clusters in insects and vertebrates. Cell 57: 347–349.
   PubMedGoogle Scholar
• Asahara, H., S. Dutta, H. Y. Kao, R. M. Evans, and M. Montminy. 1999. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Mol. Cell. Biol. 19: 8219–8225.
   PubMedGoogle Scholar
• Awgulewitsch, A., and D. Jacobs. 1992. Deformed autoregulatory element from Drosophila functions in a conserved manner in transgenic mice. Nature 358: 341–344.
   PubMed Web of Science ®Google Scholar
• Bagot, C. N., H. J. Kliman, and H. S. Taylor. 2001. Maternal Hoxa10 is required for pinopod formation in the development of mouse uterine receptivity to embryo implantation. Dev. Dyn. 222: 538–544.
   PubMedGoogle Scholar
• Bagot, C. N., P. J. Troy, and H. S. Taylor. 2000. Alteration of maternal Hoxa10 expression by in vivo gene transfection affects implantation. Gene Ther. 7: 1378–1384.
   PubMed Web of Science ®Google Scholar
• Belting, H. G., C. S. Shashikant, and F. H. Ruddle. 1998. Modification of expression and cis-regulation of Hoxc8 in the evolution of diverged axial morphology. Proc. Natl. Acad. Sci. USA 95: 2355–2360.
   PubMedGoogle Scholar
• Benson, G. V., H. Lim, B. C. Paria, I. Satokata, S. K. Dey, and R. L. Maas. 1996. Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression. Development 122: 2687–2696.
   PubMed Web of Science ®Google Scholar
• Block, K., A. Kardana, P. Igarashi, and H. S. Taylor. 2000. In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing mullerian system. FASEB J. 14: 1101–1108.
   PubMed Web of Science ®Google Scholar
• Boncinelli, E., M. Gulisano, and V. Broccoli. 1993. Emx and Otx homeobox genes in the developing mouse brain. J. Neurobiol. 24: 1356–1366.
   PubMedGoogle Scholar
• Bromleigh, V. C., and L. P. Freedman. 2000. p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. Genes Dev. 14: 2581–2586.
   PubMed Web of Science ®Google Scholar
• Chang, C. P., L. Brocchieri, W. F. Shen, C. Largman, and M. L. Cleary. 1996. Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus. Mol. Cell. Biol. 16: 1734–1745.
   PubMedGoogle Scholar
• Chang, C. P., Y. Jacobs, T. Nakamura, N. A. Jenkins, N. G. Copeland, and M. L. Cleary. 1997. Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins. Mol. Cell. Biol. 17: 5679–5687.
   PubMed Web of Science ®Google Scholar
• Chang, C. P., W. F. Shen, S. Rozenfeld, H. J. Lawrence, C. Largman, and M. L. Cleary. 1995. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev. 9: 663–674.
   PubMedGoogle Scholar
• Cohn, M. J., and C. Tickle. 1999. Developmental basis of limblessness and axial patterning in snakes. Nature 399: 474–479.
   PubMed Web of Science ®Google Scholar
• Daftary, G. S., P. J. Troy, C. N. Bagot, S. L. Young, and H. S. Taylor. 2002. Direct regulation of β3-integrin subunit gene expression by HOXA10 in endometrial cells. Mol. Endocrinol. 16: 571–579.
   PubMedGoogle Scholar
• Dalton, D., R. Chadwick, and W. McGinnis. 1989. Expression and embryonic function of empty spiracles: a Drosophila homeo box gene with two patterning functions on the anterior-posterior axis of the embryo. Genes Dev. 3: 1940–1956.
   PubMedGoogle Scholar
• Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11: 1475–1489.
   PubMed Web of Science ®Google Scholar
• Eklund, E. A., A. Jalava, and R. Kakar. 2000. Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon gamma-induced differentiation of myeloid leukemia cell lines. J. Biol. Chem. 275: 20117–20126.
   PubMedGoogle Scholar
• Favier, B., and P. Dolle. 1997. Developmental functions of mammalian Hox genes. Mol. Hum. Reprod. 3: 115–131.
   PubMedGoogle Scholar
• Ferrier, D. E., and P. W. Holland. 2001. Ancient origin of the Hox gene cluster. Nat. Rev. Genet. 2: 33–38.
   PubMedGoogle Scholar
• Grossniklaus, U., K. M. Cadigan, and W. J. Gehring. 1994. Three maternal coordinate systems cooperate in the patterning of the Drosophila head. Development 120: 3155–3171.
   PubMedGoogle Scholar
• Heberlein, U., B. England, and R. Tjian. 1985. Characterization of Drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene. Cell 41: 965–977.
   PubMedGoogle Scholar
• Holinka, C. F., H. Hata, H. Kuramoto, and E. Gurpide. 1986. Effects of steroid hormones and antisteroids on alkaline phosphatase activity in human endometrial cancer cells (Ishikawa line). Cancer Res. 46: 2771–2774.
   PubMedGoogle Scholar
• Holinka, C. F., H. Hata, H. Kuramoto, and E. Gurpide. 1986. Responses to estradiol in a human endometrial adenocarcinoma cell line (Ishikawa). J. Steroid Biochem. 24: 85–89.
   PubMedGoogle Scholar
• Jones, B., and W. McGinnis. 1993. The regulation of empty spiracles by Abdominal-B mediates an abdominal segment identity function. Genes Dev. 7: 229–240.
   PubMedGoogle Scholar
• Kastury, K., T. Druck, K. Huebner, C. Barletta, D. Acampora, A. Simeone, A. Faiella, and E. Boncinelli. 1994. Chromosome locations of human EMX and OTX genes. Genomics 22: 41–45.
   PubMedGoogle Scholar
• Knittel, T., M. Kessel, M. H. Kim, and P. Gruss. 1995. A conserved enhancer of the human and murine Hoxa-7 gene specifies the anterior boundary of expression during embryonal development. Development 121: 1077–1088.
   PubMedGoogle Scholar
• Knoepfler, P. S., and M. P. Kamps. 1995. The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1. Mol. Cell. Biol. 15: 5811–5819.
   PubMed Web of Science ®Google Scholar
• Kurita, T., P. S. Cooke, and G. R. Cunha. 2001. Epithelial-stromal tissue interaction in paramesonephric (Mullerian) epithelial differentiation. Dev. Biol. 240: 194–211.
   PubMed Web of Science ®Google Scholar
• Lessey, B. A., A. O. Ilesanmi, A. J. Castelbaum, L. Yuan, S. G. Somkuti, K. Chwalisz, and P. G. Satyaswaroop. 1996. Characterization of the functional progesterone receptor in an endometrial adenocarcinoma cell line (Ishikawa): progesterone-induced expression of the alpha1 integrin. J. Steroid Biochem. Mol. Biol. 59: 31–39.
   PubMed Web of Science ®Google Scholar
• Lu, Q., and M. P. Kamps. 1996. Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex. Mol. Cell. Biol. 16: 1632–1640.
   PubMed Web of Science ®Google Scholar
• Malicki, J., L. C. Cianetti, C. Peschle, and W. McGinnis. 1992. A human HOX4B regulatory element provides head-specific expression in Drosophila embryos. Nature 358: 345–347.
   PubMedGoogle Scholar
• Malicki, J., K. Schughart, and W. McGinnis. 1990. Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae. Cell 63: 961–967.
   PubMedGoogle Scholar
• McGinnis, N., M. A. Kuziora, and W. McGinnis. 1990. Human Hox-4.2 and Drosophila deformed encode similar regulatory specificities in Drosophila embryos and larvae. Cell 63: 969–976.
   PubMedGoogle Scholar
• McGinnis, W., and R. Krumlauf. 1992. Homeobox genes and axial patterning. Cell 68: 283–302.
   PubMed Web of Science ®Google Scholar
• Miyamoto, N., M. Yoshida, S. Kuratani, I. Matsuo, and S. Aizawa. 1997. Defects of urogenital development in mice lacking Emx2. Development 124: 1653–1664.
   PubMed Web of Science ®Google Scholar
• Morata, G., and E. Sanchez-Herrero. 1999. Patterning mechanisms in the body trunk and the appendages of Drosophila. Development 126: 2823–2828.
   PubMedGoogle Scholar
• Moskow, J. J., F. Bullrich, K. Huebner, I. O. Daar, and A. M. Buchberg. 1995. Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol. Cell. Biol. 15: 5434–5443.
   PubMed Web of Science ®Google Scholar
• Nishida, M., K. Kasahara, M. Kaneko, H. Iwasaki, and K. Hayashi. 1985. Establishment of a new human endometrial adenocarcinoma cell line, Ishikawa cells, containing estrogen and progesterone receptors. Nippon Sanka Fujinka Gakkai Zasshi 37: 1103–1111. (In Japanese.)
   PubMedGoogle Scholar
• Noyes, R. W., A. T. Hertig, and J. Rock. 1950. Dating the endometrial biopsy. Fertil. Steril. 1: 3.
   Web of Science ®Google Scholar
• Pellegrini, M., A. Mansouri, A. Simeone, E. Boncinelli, and P. Gruss. 1996. Dentate gyrus formation requires Emx2. Development 122: 3893–3898.
   PubMedGoogle Scholar
• Pinsonneault, J., B. Florence, H. Vaessin, and W. McGinnis. 1997. A model for extradenticle function as a switch that changes HOX proteins from repressors to activators. EMBO J. 16: 2032–2042.
   PubMedGoogle Scholar
• Popperl, H., M. Bienz, M. Studer, S. K. Chan, S. Aparicio, S. Brenner, R. S. Mann, and R. Krumlauf. 1995. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81: 1031–1042.
   PubMed Web of Science ®Google Scholar
• Saleh, M., I. Rambaldi, X. J. Yang, and M. S. Featherstone. 2000. Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases. Mol. Cell. Biol. 20: 8623–8633.
   PubMedGoogle Scholar
• Sandberg, E. C., N. L. Riffle, J. V. Higdon, and C. E. Getman. 1981. Pregnancy outcome in women exposed to diethylstilbestrol in utero. Am. J. Obstet. Gynecol. 140: 194–205.
   PubMed Web of Science ®Google Scholar
• Satokata, I., G. Benson, and R. Maas. 1995. Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice. Nature 374: 460–463.
   PubMed Web of Science ®Google Scholar
• Shen, W. F., J. C. Montgomery, S. Rozenfeld, J. J. Moskow, H. J. Lawrence, A. M. Buchberg, and C. Largman. 1997. AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol. Cell. Biol. 17: 6448–6458.
   PubMed Web of Science ®Google Scholar
• Shen, W. F., S. Rozenfeld, A. Kwong, L. G. Kom ves, H. J. Lawrence, and C. Largman. 1999. HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells. Mol. Cell. Biol. 19: 3051–3061.
   PubMed Web of Science ®Google Scholar
• Shen, W. F., S. Rozenfeld, H. J. Lawrence, and C. Largman. 1997. The Abd-B-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target. J. Biol. Chem. 272: 8198–8206.
   PubMedGoogle Scholar
• Simeone, A., D. Acampora, M. Gulisano, A. Stornaiuolo, and E. Boncinelli. 1992. Nested expression domains of four homeobox genes in developing rostral brain. Nature 358: 687–690.
   PubMed Web of Science ®Google Scholar
• Simeone, A., M. Gulisano, D. Acampora, A. Stornaiuolo, M. Rambaldi, and E. Boncinelli. 1992. Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 11: 2541–2550.
   PubMedGoogle Scholar
• Swift, G. H., Y. Liu, S. D. Rose, L. J. Bischof, S. Steelman, A. M. Buchberg, C. V. Wright, and R. J. MacDonald. 1998. An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2). Mol. Cell. Biol. 18: 5109–5120.
   PubMed Web of Science ®Google Scholar
• Taylor, H. S. 1998. A regulatory element of the empty spiracles homeobox gene is composed of three distinct conserved regions that bind regulatory proteins. Mol. Reprod. Dev. 49: 246–253.
   PubMedGoogle Scholar
• Taylor, H. S., A. Arici, D. Olive, and P. Igarashi. 1998. HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium. J. Clin. Investig. 101: 1379–1384.
   PubMed Web of Science ®Google Scholar
• Taylor, H. S., G. B. Vanden Heuvel, and P. Igarashi. 1997. A conserved Hox axis in the mouse and human female reproductive system: late establishment and persistent adult expression of the Hoxa cluster genes. Biol. Reprod. 57: 1338–1345.
   PubMed Web of Science ®Google Scholar
• Walldorf, U., and W. J. Gehring. 1992. Empty spiracles, a gap gene containing a homeobox involved in Drosophila head development. EMBO J. 11: 2247–2259.
   PubMedGoogle Scholar
• Yoshida, M., Y. Suda, I. Matsuo, N. Miyamoto, N. Takeda, S. Kuratani, and S. Aizawa. 1997. Emx1 and Emx2 functions in development of dorsal telencephalon. Development 124: 101–111.
   PubMedGoogle Scholar