23
Views
67
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Mediator and p300/CBP-Steroid Receptor Coactivator Complexes Have Distinct Roles, but Function Synergistically, during Estrogen Receptor α-Dependent Transcription with Chromatin Templates

&
Pages 335-348 | Received 22 Aug 2002, Accepted 15 Oct 2002, Published online: 27 Mar 2023

REFERENCES

  • Baek, H. J., S. Malik, J. Qin, and R. G. Roeder. 2002. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAFIIs. Mol. Cell. Biol. 22: 2842–2852.
  • Bhoite, L. T., Y. Yu, and D. J. Stillman. 2001. The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II. Genes Dev. 15: 2457–2469.
  • Boube, M., L. Joulia, D. L. Cribbs, and H. M. Bourbon. 2002. Evidence for a Mediator of RNA polymerase II transcriptional regulation conserved from yeast to man. Cell 110: 143–151.
  • Boyer, T. G., M. E. Martin, E. Lees, R. P. Ricciardi, and A. J. Berk. 1999. Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein. Nature 399: 276–279.
  • Bulger, M., and J. T. Kadonaga. 1994. Biochemical reconstitution of chromatin with physiological nucleosome spacing. Methods Mol. Genet. 5: 241–262.
  • Burakov, D., L. A. Crofts, C. P. Chang, and L. P. Freedman. 2002. Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor. J. Biol. Chem. 277: 14359–14362.
  • Burakov, D., C. W. Wong, C. Rachez, B. J. Cheskis, and L. P. Freedman. 2000. Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex. J. Biol. Chem. 275: 20928–20934.
  • Cosma, M. P., S. Panizza, and K. Nasmyth. 2001. Cdk1 triggers association of RNA polymerase to cell cycle promoters only after recruitment of the mediator by SBF. Mol. Cell 7: 1213–1220.
  • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11: 1475–1489.
  • Evans, R. M. 1988. The steroid and thyroid hormone receptor superfamily. Science 240: 889–895.
  • Fondell, J. D., H. Ge, and R. G. Roeder. 1996. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc. Natl. Acad. Sci. USA 93: 8329–8333.
  • Freedman, L. P. 1999. Increasing the complexity of coactivation in nuclear receptor signaling. Cell 97: 5–8.
  • Glass, C. K., and M. G. Rosenfeld. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14: 121–141.
  • Grunstein, M. 1997. Histone acetylation in chromatin structure and transcription. Nature 389: 349–352.
  • Guermah, M., S. Malik, and R. G. Roeder. 1998. Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-κB and Sp1. Mol. Cell. Biol. 18: 3234–3244.
  • Guermah, M., Y. Tao, and R. G. Roeder. 2001. Positive and negative TAFII functions that suggest a dynamic TFIID structure and elicit synergy with TRAPs in activator-induced transcription. Mol. Cell. Biol. 21: 6882–6894.
  • Hawley, D. K., and R. G. Roeder. 1987. Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. J. Biol. Chem. 262: 3452–3461.
  • Hawley, D. K., and R. G. Roeder. 1985. Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. J. Biol. Chem. 260: 8163–8172.
  • Hittelman, A. B., D. Burakov, J. A. Iniguez-Lluhi, L. P. Freedman, and M. J. Garabedian. 1999. Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins. EMBO J. 18: 5380–5388.
  • Johnson, K. M., J. Wang, A. Smallwood, C. Arayata, and M. Carey. 2002. TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA. Genes Dev. 16: 1852–1863.
  • Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S. C. Lin, R. A. Heyman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85: 403–414.
  • Kang, Y. K., M. Guermah, C. X. Yuan, and R. G. Roeder. 2002. The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro. Proc. Natl. Acad. Sci. USA 99: 2642–2647.
  • Kim, M. Y., S. J. Hsiao, and W. L. Kraus. 2001. A role for coactivators and histone acetylation in estrogen receptor alpha-mediated transcription initiation. EMBO J. 20: 6084–6094.
  • Korzus, E., J. Torchia, D. W. Rose, L. Xu, R. Kurokawa, E. M. McInerney, T. M. Mullen, C. K. Glass, and M. G. Rosenfeld. 1998. Transcription factor-specific requirements for coactivators and their acetyltransferase functions. Science 279: 703–707.
  • Kraus, W. L., and J. T. Kadonaga. 1999. Ligand- and cofactor-regulated transcription with chromatin templates, p. 167–189. In D. Picard (ed.), Steroid/nuclear receptor superfamily: a practical approach. Oxford University Press, Oxford, United Kingdom.
  • Kraus, W. L., and J. T. Kadonaga. 1998. p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation. Genes Dev. 12: 331–342.
  • Kraus, W. L., E. T. Manning, and J. T. Kadonaga. 1999. Biochemical analysis of distinct activation functions in p300 that enhance transcription initiation with chromatin templates. Mol. Cell. Biol. 19: 8123–8135.
  • Kraus, W. L., and J. Wong. 2002. Nuclear receptor-dependent transcription with chromatin. Is it all about enzymes? Eur. J. Biochem. 269: 2275–2283.
  • Lemon, B., C. Inouye, D. S. King, and R. Tjian. 2001. Selectivity of chromatin-remodelling cofactors for ligand-activated transcription. Nature 414: 924–928.
  • Leo, C., and J. D. Chen. 2000. The SRC family of nuclear receptor coactivators. Gene 245: 1–11.
  • Malik, S., and R. G. Roeder. 2000. Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. Trends Biochem. Sci. 25: 277–283.
  • Malik, S., A. E. Wallberg, Y. K. Kang, and R. G. Roeder. 2002. TRAP/SMCC/Mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4. Mol. Cell. Biol. 22: 5626–5637.
  • Mangelsdorf, D. J., C. Thummel, M. Beato, P. Herrlich, G. Schutz, K. Umesono, B. Blumberg, P. Kastner, M. Mark, P. Chambon et al.. 1995. The nuclear receptor superfamily: the second decade. Cell 83: 835–839.
  • McKenna, N. J., R. B. Lanz, and B. W. O'Malley. 1999. Nuclear receptor coregulators: cellular and molecular biology. Endocr. Rev. 20: 321–344.
  • Mittler, G., E. Kremmer, H. T. Timmers, and M. Meisterernst. 2001. Novel critical role of a human Mediator complex for basal RNA polymerase II transcription. EMBO Rep. 2: 808–813.
  • Mizzen, C. A., and C. D. Allis. 1998. Linking histone acetylation to transcriptional regulation. Cell Mol. Life Sci. 54: 6–20.
  • Naar, A. M., P. A. Beaurang, K. M. Robinson, J. D. Oliner, D. Avizonis, S. Scheek, J. Zwicker, J. T. Kadonaga, and R. Tjian. 1998. Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro. Genes Dev. 12: 3020–3031.
  • Naar, A. M., P. A. Beaurang, S. Zhou, S. Abraham, W. Solomon, and R. Tjian. 1999. Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature 398: 828–832.
  • Park, J. M., B. S. Gim, J. M. Kim, J. H. Yoon, H.-S. Kim, J.-G. Kang, and Y.-J. Kim. 2001. Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters. Mol. Cell. Biol. 21: 2312–2323.
  • Park, J. M., J. Werner, J. M. Kim, J. T. Lis, and Y. J. Kim. 2001. Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock. Mol. Cell 8: 9–19.
  • Rachez, C., and L. P. Freedman. 2001. Mediator complexes and transcription. Curr. Opin. Cell Biol. 13: 274–280.
  • Rachez, C., B. D. Lemon, Z. Suldan, V. Bromleigh, M. Gamble, A. M. Naar, H. Erdjument-Bromage, P. Tempst, and L. P. Freedman. 1999. Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. Nature 398: 824–828.
  • Roberts, S. G., B. Choy, S. S. Walker, Y. S. Lin, and M. R. Green. 1995. A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation. Curr. Biol. 5: 508–516.
  • Sandaltzopoulos, R., and P. B. Becker. 1998. Heat shock factor increases the reinitiation rate from potentiated chromatin templates. Mol. Cell. Biol. 18: 361–367.
  • Shang, Y., X. Hu, J. DiRenzo, M. A. Lazar, and M. Brown. 2000. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103: 843–852.
  • Svejstrup, J. Q., Y. Li, J. Fellows, A. Gnatt, S. Bjorklund, and R. D. Kornberg. 1997. Evidence for a mediator cycle at the initiation of transcription. Proc. Natl. Acad. Sci. USA 94: 6075–6078.
  • Taatjes, D. J., A. M. Naar, F. Andel III, E. Nogales, and R. Tjian. 2002. Structure, function, and activator-induced conformations of the CRSP coactivator. Science 295: 1058–1062.
  • Ueda, A., Y. Ishigatsubo, T. Okubo, and T. Yoshimura. 1997. Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-kappaB sites and NF-kappaB/Rel subunit specificity. J. Biol. Chem. 272: 31092–31099.
  • Wang, G., G. T. Cantin, J. L. Stevens, and A. J. Berk. 2001. Characterization of mediator complexes from HeLa cell nuclear extract. Mol. Cell. Biol. 21: 4604–4613.
  • Warnmark, A., T. Almlof, J. Leers, J. A. Gustafsson, and E. Treuter. 2001. Differential recruitment of the mammalian mediator subunit TRAP220 by estrogen receptors ER alpha and ER beta. J. Biol. Chem. 12: 12.
  • Yuan, C. X., M. Ito, J. D. Fondell, Z. Y. Fu, and R. G. Roeder. 1998. The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc. Natl. Acad. Sci. USA 95: 7939–7944.
  • Yudkovsky, N., J. A. Ranish, and S. Hahn. 2000. A transcription reinitiation intermediate that is stabilized by activator. Nature 408: 225–229.
  • Zawel, L., K. P. Kumar, and D. Reinberg. 1995. Recycling of the general transcription factors during RNA polymerase II transcription. Genes Dev. 9: 1479–1490.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.