The Histidine Triad Protein Hint Is Not Required for Murine Development or Cdk7 Function

REFERENCES

• Barnes, L. D., P. N. Garrison, Z. Siprashvili, A. Guranowski, A. K. Robinson, S. W. Ingram, C. M. Croce, M. Ohta, and F. Huebner. 1996. Fhit, a putative tumor suppressor in humans, is a dinucleoside 5′,5′′′-P-1,P-3-triphosphate hydrolase. Biochemistry 35: 11529–11535.
   PubMed Web of Science ®Google Scholar
• Bieganowski, P., P. N. Garrison, S. C. Hodawadekar, G. Faye, L. D. Barnes, and C. Brenner. 2002. Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3. J. Biol. Chem. 277: 10852–10860.
   PubMed Web of Science ®Google Scholar
• Brenner, C. 2002. Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases. Biochemistry 41: 9003–9014.
   PubMed Web of Science ®Google Scholar
• Brevet, A., J. Chen, M. Fromant, S. Blanquet, and P. Plateau. 1991. Isolation and characterization of a dinucleoside triphosphatase from Saccharomyces cerevisiae. J. Bacteriol. 173: 5275–5279.
   PubMedGoogle Scholar
• Chen, J., A. Brevet, S. Blanquet, and P. Plateau. 1998. Control of 5′,5′-dinucleoside triphosphate catabolism by APH1, a Saccharomyces cerevisiae analog of human FHIT. J. Bacteriol. 180: 2345–2349.
   PubMedGoogle Scholar
• Date, H., O. Onodera, H. Tanaka, K. Iwabuchi, K. Uekawa, S. Igarashi, R. Koike, T. Hiroi, T. Yuasa, Y. Awaya, T. Sakai, T. Takahashi, H. Nagatomo, Y. Sekijima, I. Kawachi, Y. Takiyama, M. Nishizawa, N. Fukuhara, K. Saito, S. Sugano, and S. Tsuji. 2001. Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene. Nat. Genet. 29: 184–188.
   PubMed Web of Science ®Google Scholar
• Egly, J. M. 2001. The 14th Datta Lecture. TFIIH: from transcription to clinic. FEBS Lett. 498: 124–128.
   PubMed Web of Science ®Google Scholar
• Fankhauser, H., G. A. Berkowitz, and J. A. Schiff. 1981. A nucleotide with the properties of adenosine 5′ phosphoramidate from Chlorella cells. Biochem. Biophys. Res. Commun. 101: 524–532.
   PubMedGoogle Scholar
• Fong, L. Y., V. Fidanza, N. Zanesi, L. F. Lock, L. D. Siracusa, R. Mancini, Z. Siprashvili, M. Ottey, S. E. Martin, T. Druck, P. A. McCue, C. M. Croce, and K. Huebner. 2000. Muir-Torre-like syndrome in Fhit-deficient mice. Proc. Natl. Acad. Sci. USA 97: 4742–4747.
   PubMed Web of Science ®Google Scholar
• Gilmour, J., N. Liang, and J. M. Lowenstein. 1997. Isolation, cloning and characterization of a low-molecular-mass purine nucleoside- and nucleotide-binding protein. Biochem. J. 326: 471–477.
   PubMed Web of Science ®Google Scholar
• Huebner, K., and C. M. Croce. 2001. FRA3B and other common fragile sites: the weakest links. Nat. Rev. Cancer 1: 214–221.
   PubMed Web of Science ®Google Scholar
• Kaldis, P. 1999. The cdk-activating kinase (CAK): from yeast to mammals. Cell. Mol. Life Sci. 55: 284–296.
   PubMed Web of Science ®Google Scholar
• Klein, M. G., Y. Yao, E. D. Slosberg, C. D. Lima, Y. Doki, and I. B. Weinstein. 1998. Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family. Exp. Cell Res. 244: 26–32.
   PubMed Web of Science ®Google Scholar
• Korsisaari, N., and T. P. Mäkelä. 2000. Interactions of Cdk7 and Kin28 with Hint/PKCI-1 and Hnt1 histidine triad proteins. J. Biol. Chem. 275: 34837–34840.
   PubMedGoogle Scholar
• Lallemand, Y., V. Luria, R. Haffner-Krausz, and P. Lonai. 1998. Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase. Transgenic Res. 7: 105–112.
   PubMed Web of Science ®Google Scholar
• Lam, E. W., J. Glassford, L. Banerji, N. S. Thomas, P. Sicinski, and G. G. Klaus. 2000. Cyclin D3 compensates for loss of cyclin D2 in mouse B-lymphocytes activated via the antigen receptor and CD40. J. Biol. Chem. 275: 3479–3484.
   PubMedGoogle Scholar
• Lima, C. D., M. G. Klein, and W. A. Hendrickson. 1997. Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science 278: 286–290.
   PubMed Web of Science ®Google Scholar
• Luukko, K., M. Moshnyakov, K. Sainio, M. Saarma, H. Sariola, and I. Thesleff. 1996. Expression of neurotrophin receptors during rat tooth development is developmentally regulated, independent of innervation, and suggests functions in the regulation of morphogenesis and innervation. Dev. Dyn. 206: 87–99.
   PubMed Web of Science ®Google Scholar
• Mäkelä, T. P., J. D. Parvin, J. Kim, L. J. Huber, P. A. Sharp, and R. A. Weinberg. 1995. A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription. Proc. Natl. Acad. Sci. USA 92: 5174–5178.
   PubMed Web of Science ®Google Scholar
• McDonald, J. R., U. Groschel-Stewart, and M. P. Walsh. 1987. Properties and distribution of the protein inhibitor (Mr 17,000) of protein kinase C. Biochem. J. 242: 695–705.
   PubMedGoogle Scholar
• Moreira, M. C., C. Barbot, N. Tachi, N. Kozuka, E. Uchida, T. Gibson, P. Mendonca, M. Costa, J. Barros, T. Yanagisawa, M. Watanabe, Y. Ikeda, M. Aoki, T. Nagata, P. Coutinho, J. Sequeiros, and M. Koenig. 2001. The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat. Genet. 29: 189–193.
   PubMed Web of Science ®Google Scholar
• Murphy, G. A., D. Halliday, and A. G. McLennan. 2000. The Fhit tumor suppressor protein regulates the intracellular concentration of diadenosine triphosphate but not diadenosine tetraphosphate. Cancer Res. 60: 2342–2344.
   PubMedGoogle Scholar
• Oelgeschlager, T. 2002. Regulation of RNA polymerase II activity by CTD phosphorylation and cell cycle control. J. Cell Physiol. 190: 160–169.
   PubMed Web of Science ®Google Scholar
• Ohta, M., H. Inoue, M. G. Cotticelli, K. Kastury, R. Baffa, J. Palazzo, Z. Siprashvili, M. Mori, P. McCue, T. Druck, et al. 1996. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 84: 587–597.
   PubMed Web of Science ®Google Scholar
• Patturajan, M., R. J. Schulte, B. M. Sefton, R. Berezney, M. Vincent, O. Bensaude, S. L. Warren, and J. L. Corden. 1998. Growth-related changes in phosphorylation of yeast RNA polymerase II. J. Biol. Chem. 273: 4689–4694.
   PubMedGoogle Scholar
• Pearson, J. D., D. B. DeWald, W. R. Mathews, N. M. Mozier, H. A. Zurcher-Neely, R. L. Heinrikson, M. A. Morris, W. D. McCubbin, J. R. McDonald, E. D. Fraser, et al. 1990. Amino acid sequence and characterization of a protein inhibitor of protein kinase C. J. Biol. Chem. 265: 4583–4591.
   PubMed Web of Science ®Google Scholar
• Rossi, D. J., A. Londesborough, N. Korsisaari, A. Pihlak, E. Lehtonen, M. Henkemeyer, and T. P. Mäkelä. 2001. Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1. EMBO J. 20: 2844–2856.
   PubMedGoogle Scholar
• Rubio-Texeira, M., J. M. Varnum, P. Bieganowski, and C. Brenner. 2002. Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae. BMC Mol. Biol. 3: 7.
   PubMedGoogle Scholar
• Siprashvili, Z., G. Sozzi, L. D. Barnes, P. McCue, A. K. Robinson, V. Eryomin, L. Sard, E. Tagliabue, A. Greco, L. Fusetti, G. Schwartz, M. A. Pierotti, C. M. Croce, and K. Huebner. 1997. Replacement of Fhit in cancer cells suppresses tumorigenicity. Proc. Natl. Acad. Sci. USA 94: 13771–13776.
   PubMed Web of Science ®Google Scholar
• Werner, N. S., Z. Siprashvili, L. Y. Fong, G. Marquitan, J. K. Schroder, W. Bardenheuer, S. Seeber, K. Huebner, J. Schutte, and B. Opalka. 2000. Differential susceptibility of renal carcinoma cell lines to tumor suppression by exogenous Fhit expression. Cancer Res. 60: 2780–2785.
   PubMed Web of Science ®Google Scholar
• Wilkinson, D. G., and J. Green. 1990. In situ hybridization and the three-dimensional reconstruction of serial sections, p. 155-171. In A. J. Copp and D. L. Cockroft (ed.), Postimplantation mammalian embryos: a practical approach. IRL Press, Oxford, England.
   Google Scholar
• Zanesi, N., V. Fidanza, L. Y. Fong, R. Mancini, T. Druck, M. Valtieri, T. Rudiger, P. A. McCue, C. M. Croce, and K. Huebner. 2001. The tumor spectrum in FHIT-deficient mice. Proc. Natl. Acad. Sci. USA 98: 10250–10255.
   PubMedGoogle Scholar