13
Views
24
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

CtBP-Independent Repression in the Drosophila Embryo

, &
Pages 3990-3999 | Received 16 Sep 2002, Accepted 21 Feb 2003, Published online: 27 Mar 2023

REFERENCES

  • Arnosti, D. N., S. Gray, S. Barolo, J. Zhou, and M. Levine. 1996. The gap protein knirps mediates both quenching and direct repression in the Drosophila embryo. EMBO J. 15: 3659–3666.
  • Boyd, J. M., T. Subramanian, U. Schaeper, M. La Regina, S. Bayley, and G. Chinnadurai. 1993. A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis. EMBO J. 12: 469–478.
  • Chou, T. B., and N. Perrimon. 1996. The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144: 1673–1679.
  • Gateff, E., L. Gissmann, R. Shrestha, N. Plus, H. Pfister, J. Schroeder, and H. Zur Hausen. 1980. Characterization of two tumorous blood cell lines of Drosophila melanogaster and the viruses they contain, p. 517–533. In E. Kurstak, K. Maramarosch, and A. Dubendorfer (ed.), Invertebrate systems in vitro. Elsevier/North-Holland Biomedical Press, Amsterdam, The Netherlands.
  • Gaul, U., and H. Jackle. 1989. Analysis of maternal effect mutant combinations elucidates regulation and function of the overlap of hunchback and Kruppel gene expression in the Drosophila blastoderm embryo. Development 107: 651–662.
  • Gray, S., P. Szymanski, and M. Levine. 1994. Short-range repression permits multiple enhancers to function autonomously within a complex promoter. Genes Dev. 8: 1829–1838.
  • Gray, S., H. Cai, S. Barolo, and M. Levine. 1995. Transcriptional repression in the Drosophila embryo. Phil. Trans. R. Soc. Lond. B Biol. Sci. 349: 257–262.
  • Gray, S., and M. Levine. 1996. Short-range transcriptional repressors mediate both quenching and direct repression within complex loci in Drosophila. Genes Dev. 10: 700–710.
  • Gray, S., and M. Levine. 1996. Transcriptional repression in development. Curr. Opin. Cell Biol. 8: 358–364.
  • Ip, Y. T., R. Kraut, M. Levine, and C. A. Rushlow. 1991. The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in Drosophila. Cell 64: 439–446.
  • Ip, Y. T., R. E. Park, D. Kosman, E. Bier, and M. Levine. 1992. The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo. Genes Dev. 6: 1728–1739.
  • Jiang, J., D. Kosman, Y. T. Ip, and M. Levine. 1991. The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos. Genes Dev. 5: 1881–1891.
  • Keller, S. A., Y. Mao, P. Struffi, C. Margulies, C. E. Yurk, A. R. Anderson, R. L. Amey, S. Moore, J. M. Ebels, K. Foley, M. Corado, and D. N. Arnosti. 2000. dCtBP-dependent and -independent repression activities of the Drosophila Knirps protein. Mol. Cell. Biol. 20: 7247–7258.
  • Kirkpatrick, H., K. Johnson, and A. Laughon. 2001. Repression of dpp targets by binding of brinker to Smad sites. J. Biol. Chem. 276: 18216–18222.
  • La Rosee, A., T. Häder, H. Taubert, R. Rivera-Pomar, and H. Jäckle. 1997. Mechanism and Bicoid-dependent control of hairy stripe 7 expression in the posterior region of the Drosophila embryo. EMBO J. 16: 4403–4411.
  • La Rosee-Borggreve, A., T. Häder, D. Wainwright, F. Sauer, and H. Jäckle. 1999. hairy stripe 7 element mediates activation and repression in response to different domains and levels of Krüppel in the Drosophila embryo. Mech. Dev. 89: 133–140.
  • Licht, J. D., W. Hanna-Rose, J. C. Reddy, M. A. English, M. Ro, M. Grossel, R. Shaknovich, and U. Hansen. 1994. Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein. Mol. Cell. Biol. 14: 4057–4066.
  • Malik, S., and R. G. Roeder. 2000. Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. Trends Biochem. Sci. 25: 277–283.
  • Mannervik, M., Y. Nibu, H. Zhang, and M. Levine. 1999. Transcriptional coregulators in development. Science 284: 606–609.
  • Nibu, Y., H. Zhang, and M. Levine. 1998. Interaction of short-range repressors with Drosophila CtBP in the embryo. Science 280: 101–104.
  • Nibu, Y., H. Zhang, E. Bajor, S. Barolo, S. Small, and M. Levine. 1998. dCtBP mediates transcriptional repression by Knirps, Krüppel, and Snail in the Drosophila embryo. EMBO J. 17: 7009–7020.
  • Nibu, Y., H. Zhang, and M. Levine. 2001. Local action of long-range repressors in the Drosophila embryo. EMBO J. 20: 2246–2253.
  • Poortinga, G., M. Watanabe, and S. M. Parkhurst. 1998. Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression. EMBO J. 17: 2067–2078.
  • Ptashne, M., and A. Gann. 2001. Genes and signals. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Redemann, N., U. Gaul, and H. Jackle. 1988. Disruption of a putative Cys-zinc interaction eliminates the biological activity of the Kruppel finger protein. Nature 332: 90–92.
  • Rio, D. C., and G. M. Rubin. 1985. Transformation of cultured Drosophila melanogaster cells with a dominant selectable marker. Mol. Cell. Biol. 5: 1833–1838.
  • Rubin, G. M., and A. C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218: 348–353.
  • Rundlett, S. E., A. A. Carmen, N. Suka, B. M. Turner, and M. Grunstein. 1998. Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3. Nature 392: 831–835.
  • Rushlow, C., P. F. Colosimo, M. C. Lin, M. Xu, and N. Kirov. 2001. Transcriptional regulation of the Drosophila gene zen by competing Smad and Brinker inputs. Genes Dev. 15: 340–351.
  • Saller, E., and M. Bienz. 2001. Direct competition between Brinker and Drosophila Mad in Dpp target gene transcription. EMBO Rep. 2: 298–305.
  • Schaeper, U., J. M. Boyd, S. Verma, E. Uhlmann, T. Subramanian, and G. Chinnadurai. 1995. Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc. Natl. Acad. Sci. USA 92: 10467–10471.
  • Small, S., R. Kraut, T. Hoey, R. Warrior, and M. Levine. 1991. Transcriptional regulation of a pair-rule stripe in Drosophila. Genes Dev. 5: 827–839.
  • Small, S., A. Blair, and M. Levine. 1992. Regulation of even-skipped stripe 2 in the Drosophila embryo. EMBO J. 11: 4047–4057.
  • Small, S., D. N. Arnosti, and M. Levine. 1993. Spacing ensures autonomous expression of different stripe enhancers in the even-skipped promoter. Development 119: 767–772.
  • Small, S., A. Blair, and M. Levine. 1996. Regulation of two pair-rule stripes by a single enhancer in the Drosophila embryo. Dev. Biol. 175: 314–324.
  • Sollerbrant, K., G. Chinnadurai, and C. Svensson. 1996. The CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation. Nucleic Acids Res. 24: 2578–2584.
  • Stanojevic, D., T. Hoey, and M. Levine. 1989. Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila. Nature 341: 331–335.
  • Thummel, C. S., A. M. Boulet, and H. D. Lipshitz. 1988. Vectors for Drosophila P-element-mediated transformation and tissue culture transfection. Gene 74: 445–456.
  • Woychik, N. A., and M. Hampsey. 2002. The RNA polymerase II machinery: structure illuminates function. Cell 108: 453–463.
  • Yan, R., S. Small, C. Desplan, C. R. Dearolf, and J. E. Darnell, Jr. 1996. Identification of a Stat gene that functions in Drosophila development. Cell 84: 421–430.
  • Zhang, Q. D., W. Piston, and R. H. Goodman. 2002. Regulation of corepressor function by nuclear NADH. Science 295: 895–897.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.