Targeted Disruption of the Mouse Mel_1b Melatonin Receptor

REFERENCES

• Bartness, T. J., E. L. Bittman, M. H. Hastings, J. B. Powers, and B. D. Goldman. 1993. Timed melatonin infusion paradigm for melatonin delivery: what has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses? J. Pineal Res. 15: 161–190.
   PubMed Web of Science ®Google Scholar
• Benloucif, S., M. I. Masana, K. Yun, and M. L. Dubocovich. 1999. Interactions between light and melatonin on the circadian clock of mice. J. Biol. Rhythms 14: 281–289.
   PubMed Web of Science ®Google Scholar
• Benloucif, S., and M. L. Dubocovich. 1996. Melatonin and light induce phase shifts of circadian activity rhythms in the C3H/HeN mouse. J. Biol. Rhythms 11: 113–125.
   PubMed Web of Science ®Google Scholar
• Cassone, V. M. 1990. Effects of melatonin on vertebrate circadian systems. Trends Neurosci. 13: 457–464.
   PubMed Web of Science ®Google Scholar
• Cheng, Y., and W. H. Prusoff. 1973. Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 22: 3099–3108.
   PubMed Web of Science ®Google Scholar
• Doolen, S., D. N. Krause, M. L. Dubocovich, and S. P. Duckles. 1998. Melatonin mediates two distinct responses in vascular smooth muscle. Eur. J. Pharmacol. 345: 67–69.
   PubMed Web of Science ®Google Scholar
• Drew, J. E., P. Barrett, L. M. Williams, S. Conway, and P. J. Morgan. 1998. The ovine melatonin-related receptor: cloning and preliminary distribution and binding studies. J. Neuroendocrinol. 10: 651–661.
   PubMedGoogle Scholar
• Dubocovich, M. L., M. I. Masana, S. Jacob, and D. M. Sauri. 1997. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroceptor. Naunyn-Schmiedeberg's Arch. Pharmacol. 355: 365–375.
   Google Scholar
• Dubocovich, M. L., K. Yun, W. M. Al-Ghoul, S. Benloucif, and M. I. Masana. 1998. Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB J. 12: 1211–1220.
   PubMed Web of Science ®Google Scholar
• Dubocovich, M. L., D. P. Cardinali, P. Delagrange, D. N. Krause, A. D. Strosberg, D. Sugden, and F. D. Yocca. 2000. The IUPHAR compendium of receptor characterisation and classification, 2nd ed., p. 187–193. IUPHAR Media, London, United Kingdom.
   Google Scholar
• Ebihara, S., T. Marks, D. J. Hudson, and M. Menaker. 1986. Genetic control of melatonin synthesis in the pineal gland of the mouse. Science 231: 491–493.
   PubMed Web of Science ®Google Scholar
• Gaildrat, P., F. Becq, and J. Falcon. 2002. First cloning and functional characterization of a melatonin receptor in fish brain: a novel one? J. Pineal Res. 32:74–84.
   PubMed Web of Science ®Google Scholar
• Ganguly, S., S. L. Coon, and D. C. Klein. 2002. Control of melatonin synthesis in the mammalian pineal gland: the critical role of serotonin acetylation. Cell Tissue Res. 309: 127–138.
   PubMedGoogle Scholar
• Gribkoff, V. K., R. L. Pieschl, T. A. Wisialowski, A. N. van den Pol, and F. D. Yocca. 1998. Phase shifting of circadian rhythms and depression of neuronal activity in the rat suprachiasmatic nucleus by neuropeptide Y: mediation by different receptor subtypes. J. Neurosci. 18: 3014–3022.
   PubMed Web of Science ®Google Scholar
• Ginty, D. D., J. M. Kornhauser, M. A. Thompson, H. Bading, K. E. Mayo, J. S. Takahashi, and M. E. Greenberg. 1993. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science 260: 238–241.
   PubMedGoogle Scholar
• Gubitz, A. K., and S. M. Reppert. 1999. Assignment of the melatonin-related receptor to human chromosome X (GPR50) and mouse chromosome X (Gpr50). Genomics 55: 248–251.
   PubMedGoogle Scholar
• Hannibal, J. 2002. Neurotransmitters of the retinohypothalamic tract. Cell Tissue Res. 309: 73–88.
   PubMed Web of Science ®Google Scholar
• Hastings, M. H., S. M. Mead, R. R. Vindlacheruvu, F. J. Ebling, E. S. Maywood, and J. Grosse. 1992. Non-photic phase shifting of the circadian activity rhythm of Syrian hamsters: the relative potency of arousal and melatonin. Brain Res. 591: 20–26.
   PubMed Web of Science ®Google Scholar
• Hunt, A. E., W. M. Al-Ghoul, M. U. Gillette, and M. L. Dubocovich. 2001. Activation of MT2 melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock. Am. J. Physiol. 280: C110–C118.
   PubMed Web of Science ®Google Scholar
• Kopp, M., H. Meissl, and H. W. Korf. 1997. The pituitary adenylate cyclase-activating polypeptide-induced phosphorylation of the transcription factor CREB (cAMP response element binding protein) in the rat suprachiasmatic nucleus is inhibited by melatonin. Neurosci. Lett. 227: 145–148.0
   PubMedGoogle Scholar
• Lewy, A. J., S. Ahmed, J. M. Jackson, and R. L. Sack. 1992. Melatonin shifts human circadian rhythms according to a phase-response curve. Chronobiol. Int. 9: 380–392.
   PubMed Web of Science ®Google Scholar
• Lewy, A. J., V. K. Bauer, B. P. Hasler, A. R. Kendall, M. L. Pires, and R. L. Sack. 2001. Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin. Brain Res. 918: 96–100.
   PubMed Web of Science ®Google Scholar
• Liu, C., D. R. Weaver, X. Jin, L. P. Shearman, R. L. Pieschl, V. K. Gribkoff, and S. M. Reppert. 1997. Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron 19: 91–102.
   PubMed Web of Science ®Google Scholar
• Malpaux, B., M. Migaud, H. Tricoire, and P. Chemineau. 2001. Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin. J. Biol. Rhythms 16: 336–347.
   PubMed Web of Science ®Google Scholar
• Margraf, R. R., and G. R. Lynch. 1993. Melatonin injections affect circadian behavior and SCN neurophysiology in Djungarian hamsters. Am. J. Physiol. 264: R615–R621.
   PubMedGoogle Scholar
• McArthur, A. J., A. E. Hunt, and M. U. Gillette. 1997. Melatonin action and signal transduction in the rat suprachiasmatic circadian clock: activation of protein kinase C at dusk and dawn. Endocrinology 138: 627–634.
   PubMed Web of Science ®Google Scholar
• Messager, S., M. L. Garabette, M. H. Hastings, and D. G. Hazlerigg. 2001. Tissue-specific abolition of Per1 expression in the pars tuberalis by pinealectomy in the Syrian hamster. NeuroReport 12: 1–4.
   PubMedGoogle Scholar
• Reebs, S. G., and N. Mrosovsky. 1989. Effects of induced wheel running on the circadian activity rhythms of Syrian hamsters: entrainment and phase response curve. J. Biol. Rhythms 4: 39–48.
   PubMed Web of Science ®Google Scholar
• Reppert, S. M., D. R. Weaver, and T. Ebisawa. 1994. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 13: 1177–1185.
   PubMed Web of Science ®Google Scholar
• Reppert, S. M., C. Godson, C. D. Mahle, D. R. Weaver, S. A. Slaugenhaupt, and J. F. Gusella. 1995. Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b-melatonin receptor. Proc. Natl. Acad. Sci. USA 92: 8734–8738.
   PubMed Web of Science ®Google Scholar
• Reppert, S. M., D. R. Weaver, V. M. Cassone, C. Godson, and L. F. Kolakowski, Jr. 1995. Melatonin receptors are for the birds: molecular analysis of two receptor subtypes differentially expressed in chick brain. Neuron 15: 1003–1015.
   PubMed Web of Science ®Google Scholar
• Reppert, S. M., D. R. Weaver, T. Ebisawa, C. D. Mahle, and L. F. Kolakowski, Jr. 1996. Cloning of a melatonin-related receptor from human pituitary. FEBS Lett. 386: 219–224.
   PubMed Web of Science ®Google Scholar
• Reppert, S. M., D. R. Weaver, and C. Godson. 1996. Melatonin receptors step into the light: cloning and classification of subtypes. Trends Pharmacol. Sci. 17: 100–102.
   PubMed Web of Science ®Google Scholar
• Roca, A. L., C. Godson, D. R. Weaver, and S. M. Reppert. 1997. Structure, characterization, and expression of the gene encoding the mouse Mel1a melatonin receptor. Endocrinology 137: 3469–3477.
   Google Scholar
• Roseboom, P. H., M. A. A. Namboodiri, D. B. Zimonjic, N. C. Popescu, I. R. Rodriguez, J. A. Gastel, and D. C. Klein. 1998. Natural melatonin ′knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase. Mol. Brain Res. 63: 189–197.
   PubMedGoogle Scholar
• Rusak, B., and G. D. Yu. 1993. Regulation of melatonin-sensitivity and firing-rate rhythms of hamster suprachiasmatic nucleus neurons: pinealectomy effects. Brain Res. 602: 200–204.
   PubMedGoogle Scholar
• Ting, K. N., N. A. Blaylock, and D. Sugden. 1999. Molecular and pharmacological evidence for MT1 receptor subtypes in tail artery of juvenile Wistar rats. Br. J. Pharmacol. 127: 987–995.
   PubMed Web of Science ®Google Scholar
• Travnickova-Bendova, Z., N. Cermakian, S. M. Reppert, P. Sassone-Corsi. 2002. Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity. Proc. Natl. Acad. Sci. USA 99: 7728–7733.
   PubMed Web of Science ®Google Scholar
• Viswanathan, N., and F. C. Davis. 1997. Single prenatal injections of melatonin or the D1-dopamine receptor agonist SKF 38393 to pregnant hamsters sets the offsprings' circadian rhythms to phases 180 degrees apart. J. Comp. Physiol. [A] 180: 339–346.
   PubMedGoogle Scholar
• von Gall, C., G. Duffield, M. Hastings, M. D. Kopp, F. Dehghani, H. W. Korf, and J. H. Stehle. 1998. CREB in the mouse SCN: a molecular integrator coding the phase adjusting stimuli of light, glutamate, PACAP and melatonin for clockwork access. J. Neurosci. 18: 10389–10397.
   PubMed Web of Science ®Google Scholar
• von Gall, C., D. R. Weaver, M. Kock, H. W. Korf, and J. H. Stehle. 2000. Melatonin limits transcriptional impact of phosphoCREB in the mouse SCN via the Mel1a receptor. NeuroReport 11: 1803–1807.
   PubMed Web of Science ®Google Scholar
• von Gall, C., M. L. Garabette, C. A. Kell, S. Frenzel, F. Dehghani, P. M. Schumm-Draeger, D. R. Weaver, H. W. Korf, M. H. Hastings, and J. H. Stehle. 2002. Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin. Nat. Neurosci. 5: 234–238.
   PubMed Web of Science ®Google Scholar
• von Gall, C., J. H. Stehle, and D. R. Weaver. 2002. Mammalian melatonin receptors: molecular biology and signal transduction. Cell Tissue Res. 309: 151–162.
   PubMed Web of Science ®Google Scholar
• Wan, Q., H. Y. Man, F. Liu, J. Braunton, N. B. Niznik, S. F. Pang, G. M. Brown, and Y. T. Wang. 1999. Differential modulation of GABAA receptor function by Mel1a and Mel1b receptors. Nat. Neurosci. 2: 401–403.
   PubMed Web of Science ®Google Scholar
• Watson, S., and S. Arkinstall. 1994. The G-protein linked receptor factsbook. Academic Press, San Diego, Calif.
   Google Scholar
• Weaver, D. R. 1999. Melatonin and circadian rhythmicity in vertebrates. Physiological roles and pharmacological effects, p. 197-262 In F. W. Turek and P. C. Zee (ed.), Regulation of sleep and circadian rhythms. Marcel Dekker, Inc., New York, N.Y.
   Google Scholar
• Weaver, D. R., C. Liu, and S. M. Reppert. 1996. Nature's knockout: the Mel1b receptor is not necessary for circadian or reproductive responses in Siberian hamsters. Mol. Endocrinol. 10: 1478–1487.
   PubMedGoogle Scholar