29
Views
242
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Identification of a Structural Determinant Necessary for the Localization and Function of Estrogen Receptor α at the Plasma Membrane

, , , , &
Pages 1633-1646 | Received 19 Jul 2002, Accepted 06 Dec 2002, Published online: 27 Mar 2023

REFERENCES

  • Albanese, C., J. Johnson, G. Watanabe, N. Eklund, D. Vu, A. Arnold, and R. G. Pestell. 1995. Transforming p21 ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J. Biol. Chem. 270: 23589–23597.
  • Alton, G., M. Hasilik, R. Niehues, K. Paneerselvam, J. R. Etchison, F. Fana, and H. H. Freeze. 1998. Direct utilization of mannose for mammalian glycoprotein biosynthesis. Glycobiology 8: 285–295.
  • Anderson, R. G. 1998. The caveolae membrane system. Annu. Rev. Biochem. 67: 199–225.
  • Aronica, S. M., W. L. Kraus, and B. S. Katzenellenbogen. 1994. Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc. Natl. Acad. Sci. USA 91: 8517–8521.
  • Catoria, G., M. V. Barone, M. Di Domenico, A. Bilancio, D. Ametrano, A. Migliaccio, and F. Auricchio. 1999. Non-transcriptional action of oestradiol and progestin triggers DNA synthesis. EMBO J. 18: 2500–2510.
  • Chambliss, K. L., I. S. Yuhanna, C. Mineo, P. Liu, Z. German, T. S. Sherman, M. E. Mendelsohn, R. G. W. Anderson, and P. W. Shaul. 2000. Estrogen receptor α and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae. Circ. Res. 87: e44–e52.
  • Cooper, L. F., J. C. Tiffee, J. P. Griffin, H. Hamano, and Z. Guo. 2000. Estrogen-induced resistance to osteoblast apoptosis is associated with increased hsp27 expression. J. Cell. Physiol. 185: 401–407.
  • Donovan, J. C. H., A. Milic, and J. M. Slingerland. 2001. Constitutive MEK/MAPK activation leads to p27kip1 deregulation and antiestrogen resistance in human breast cancer cells. J. Biol. Chem. 276: 40888–40895.
  • Duan, R., W. Xie, and S. Safe. 2001. Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1. J. Biol. Chem. 276: 11590–11598.
  • Filardo, E. J., J. A. Quinn, K. I. Bland, and R. A. Frackelton, Jr. 2000. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, gpr30, and occurs via transactivation of the epidermal growth factor receptor through release of HB-EGF. Mol. Endocrinol. 14: 1649–1660.
  • Greene, G., N. Sobel, W. King, and E. Jensen. 1984. Immunochemical studies of estrogen receptors. J. Steroid Biochem. 20: 51–56.
  • Holt, A., G. Alton, C. H. Scaman, G. Loppnow, A. Szpacenko, I. Svendsen, and M. M. Palcic. 1998. Identification of the quinone growth cofactor in mammalian semicarbazide-sensitive amine oxidase. Biochemistry 37: 4946–4957.
  • Kim, H. P., J. Y. Lee, J. K. Jeong, S. W. Bae, H. K. Lee, and I. Jo. 1999. Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor alpha localized in caveolae. Biochem. Biophys. Res. Commun. 263: 257–262.
  • Kousteni, S., T. Bellido, L. I. Plotkin, C. A. O'Brien, D. L. Bodenner, L. Han, K. Han, G. B. DiGregorio, J. A. Katzenellenbogen, B. S. Katzenellenbogen, P. K. Roberson, R. S. Weinstein, R. L. Jilka, and S. C. Manolagas. 2001. Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. Cell 104: 719–730.
  • Lavoie, J. N., G. L'Allemain, A. Brunet, R. Muller, and J. Pouyssegur. 1996. Cyclin D1 expression is regulated by the p42/p44 MAPK and negatively by the p38/HOG MAPK pathway. J. Biol. Chem. 271: 20608–20616.
  • Le Mellay, V., B. Grosse, and M. Lieberherr. 1997. Phospholipase C beta and membrane action of calcitriol and estradiol. J. Biol. Chem. 272: 11902–11907.
  • Levin, E. R. 1999. Cellular functions of the plasma membrane estrogen receptor. Trends Endocrinol. Metab. 10: 374–376.
  • Lieberherr, M., B. Grosse, M. Kachkache, and S. Balsan. 1993. Cell signaling and estrogens in female rat osteoblasts: a possible involvement of unconventional non-nuclear receptors. J. Bone Min. Res. 8: 1365–1376.
  • Lobenhofer, E. K., G. Huper, J. D. Iglehart, and J. R. Marks. 2000. Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis. Cell Growth Differ. 11: 99–110.
  • Lu, M. L., M. C. Schneider, Y. Zhang, and J. P. Richie. 2001. Caveolin-1 interacts with androgen receptor: a positive modulator of androgen receptor mediated transactivation. J. Biol. Chem. 276: 13442–13451.
  • Lublin, D. 1992. Glucosyl-phosphatidylinositol anchoring of membrane proteins. Curr. Top. Microbiol. Immunol. 178: 142–168.
  • Mandava, M. B. 1988. Plant growth-promoting brassinosteroids. Annu. Rev. Plant Physiol. Plant Mol. Biol. 39: 23–52.
  • Marquez, D. C., and R. J. Pietras. 2001. Membrane-associated binding sites for estrogen contribute to growth regulation of human breast cancer cells. Oncogene 20: 5420–5430.
  • Migliaccio, A., M. Di Domenico, G. Castoria, A. de Falco, P. Bontempo, E. Nola, and F. Auricchio. 1996. Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells. EMBO J. 15: 1292–1300.
  • Morey, A. K., A. Pedram, M. Razandi, B. A. Prins, R.-M. Hu, E. Biesiada, and E. R. Levin. 1997. Estrogen and progesterone inhibit human vascular smooth muscle proliferation. Endocrinology 138: 3330–3339.
  • Norfleet, A. M., M. L. Thomas, B. Gametchu, and C. S. Watson. 1999. Estrogen receptor-alpha detected on the plasma membrane of aldehyde-fixed GH3/B6/F10 rat pituitary tumor cells by enzyme-linked immunocytochemistry. Endocrinology 140: 3805–3814.
  • Okamoto, T., A. Schlegel, P. E. Scherer, and M. P. Lisanti. 1998. Caveolins, a family of scaffolding proteins for organizing “preassembled signaling complexes” at the plasma membrane. J. Biol. Chem. 273: 5419–5422.
  • Pedram, A., M. Razandi, and E. R. Levin. 1998. Extracellular regulated kinase/jun kinase cross-talk underlies vascular endothelial cell growth factor-induced endothelial cell proliferation. J. Biol. Chem. 273: 26722–26728.
  • Pettersson, K., F. Delaunay, and J. A. Gustafsson. 2000. Estrogen receptor beta acts as a dominant regulator of estrogen signaling. Oncogene 19: 4970–4978.
  • Pietras, R., and C. M. Szego. 1977. Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells. Nature 265: 69–72.
  • Razandi, M., P. Oh, A. Pedram, J. Schnitzer, and E. R. Levin. 2002. Estrogen receptors associate with and regulate the production of caveolin: implications for signaling and cellular actions. Mol. Endocrinol. 16: 100–115.
  • Razandi, M., A. Pedram, G. L. Greene, and E. R. Levin. 1999. Cell membrane and nuclear estrogen receptors derive from a single transcript: studies of ERα and ERβ expressed in CHO cells. Mol. Endocrinol. 13: 307–319.
  • Razandi, M., A. Pedram, and E. R. Levin. 2000. Estrogen signals to preservation of endothelial cell form and function. J. Biol. Chem. 275: 38540–38546.
  • Razandi, M., A. Pedram, and E. R. Levin. 2000. Plasma membrane estrogen receptors signal to anti-apoptosis in breast cancer. Mol. Endocrinol. 14: 1434–1447.
  • Resh, M. D. 1996. Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins. Cell. Signal. 8: 403–412.
  • Russell, K. S., M. P. Haynes, D. Sinha, E. Clerisme, and J. R. Bender. 2000. Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. Proc. Natl. Acad. Sci. USA 97: 5930–5935.
  • Schlegel, A., C. Wang, R. G. Pestell, and M. P. Lisanti. 2001. Ligand-independent activation of oestrogen receptor α by caveolin-1. Biochem. J. 359: 203–210.
  • Schnitzer, J. E., D. P. McIntosh, A. M. Dvorak, J. Liu, and P. Oh. 1995. Separation of caveolae from associated microdomains of GPI-anchored proteins. Science 269: 1435–1439.
  • Sherr, C. J. 1993. Mammalian G1 cyclins. Cell 73: 1059–1065.
  • Simoncini, T., A. Hafezi-Moghadam, D. P. Brazil, K. Ley, W. W. Chin, and J. K. Liao. 2000. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407: 538–541.
  • Tesarik, J., and C. Mendoza. 1995. Nongenomic effects of 17β-estradiol on maturing human oocytes: relationship to oocyte developmental potential. J. Clin. Endocrinol. Metab. 80: 1438–1443.
  • Truss, M., and M. Beato. 1993. Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors. Endocrine Rev. 14: 459–479.
  • Valentine, J. E., E. Kalkhoven, R. White, S. Hoare, and M. G. Parker. 2000. Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression. J. Biol. Chem. 275: 25322–25329.
  • Wang, Z.-Y., H. Seto, S. Fujioka, S. Yoshida, and J. Chory. 2001. BRl1 is a critical component of a plasma-membrane receptor for plant steroids. Nature 410: 380–383.
  • Watters, J. J., J. S. Campbell, M. J. Cunningham, E. G. Krebs, and D. M. Dorsa. 1997. Rapid membrane effects of steroids in neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription. Endocrinology 138: 4030–4033.
  • Watters, J. J., T. Y. Chun, Y. N. Kim, P. J. Bertics, and J. Gorski. 2000. Estrogen modulation of prolactin gene expression requires an intact mitogen-activated protein kinase signal transduction pathway in cultured rat pituitary cells. Mol. Endocrinol. 14: 1872–1881.
  • Watts, C. K., K. J. Sweeney, A. Warlters, E. A. Musgrove, and R. L. Sutherland. 1994. Antiestrogen regulation of cell cycle progression and cyclin D1 gene expression in MCF-7 human breast cancer cells. Breast Canc. Res. Treat. 31: 95–105.
  • White, R., J. A. Lees, M. Needham, J. Ham, and M. Parker. 1987. Structural organization and expression of the mouse estrogen receptor. Mol. Endocrinol. 1: 735–744.
  • Wise, P. M., D. B. Dubal, M. E. Wislon, S. W. Rau, and M. Bottner. 2001. Neuroprotective effects of estrogen—new insights into mechanisms of action. Endocrinology 142: 969–973.
  • Wyckoff, M. H., K. L. Chambliss, C. Mineo, I. S. Yuhanna, M. E. Mendelsohn, S. M. Mumby, and P. W. Shaul. 2001. Plasma membrane estrogen receptors are coupled to endothelial nitric-oxide synthase through Gαi. J. Biol. Chem. 276: 27071–27076.
  • Yu, Q., Y. Geng, and P. Sicinski. 2001. Specific protection against breast cancers by cyclin D1 ablation. Nature 411: 1017–1021.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.