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Transcriptional Regulation

War1p, a Novel Transcription Factor Controlling Weak Acid Stress Response in Yeast

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Pages 1775-1785 | Received 09 Sep 2002, Accepted 13 Dec 2002, Published online: 27 Mar 2023

REFERENCES

  • Adams, A., D. E. Gottschling, C. A. Kaiser, and T. Stearns. 1997. Methods in yeast genetics: a laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Balzi, E., M. Wang, S. Leterme, L. Van Dyck, and A. Goffeau. 1994. PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J. Biol. Chem. 269: 2206–2214.
  • Bissinger, P. H., and K. Kuchler. 1994. Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance. J. Biol. Chem. 269: 4180–4186.
  • Bracey, D., C. D. Holyoak, and P. J. Coote. 1998. Comparison of the inhibitory effect of sorbic acid and amphotericin B on Saccharomyces cerevisiae: is growth inhibition dependent on reduced intracellular pH? J. Appl. Microbiol. 85: 1056–1066.
  • Cui, Z., T. Shiraki, D. Hirata, and T. Miyakawa. 1998. Yeast gene YRR1, which is required for resistance to 4-nitroquinoline N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2. Mol. Microbiol. 29: 1307–1315.
  • Deak, T. 1991. Food-borne yeasts. Adv. Appl. Microbiol. 36: 179–278.
  • Delahodde, A., T. Delaveau, and C. Jacq. 1995. Positive autoregulation of the yeast transcription factor Pdr3p, which is involved in control of drug resistance. Mol. Cell. Biol. 15: 4043–4051.
  • DeRisi, J., B. van den Hazel, P. Marc, E. Balzi, P. Brown, C. Jacq, and A. Goffeau. 2000. Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants. FEBS Lett. 470: 156–160.
  • Des Etages, S. A., D. Saxena, H. L. Huang, D. A. Falvey, D. Barber, and M. C. Brandriss. 2001. Conformational changes play a role in regulating the activity of the proline utilization pathway-specific regulator in Saccharomyces cerevisiae. Mol. Microbiol. 40: 890–899.
  • Egner, R., and K. Kuchler. 1996. The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole. FEBS Lett. 378: 177–181.
  • Egner, R., Y. Mahé, R. Pandjaitan, and K. Kuchler. 1995. Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 5879–5887.
  • Fernandes, L., C. Rodrigues-Pousada, and K. Struhl. 1997. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol. Cell. Biol. 17: 6982–6993.
  • Friden, P., and P. Schimmel. 1987. LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes. Mol. Cell. Biol. 7: 2708–2717.
  • Gürner, W., E. Durchschlag, M. T. Martinez-Pastor, F. Estruch, G. Ammerer, B. Hamilton, H. Ruis, and C. Schüller. 1998. Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev. 12: 586–597.
  • Guo, H., and G. B. Kohlhaw. 1996. Regulation of transcription in mammalian cells by yeast Leu3p and externally supplied inducer. FEBS Lett. 390: 191–195.
  • Hedges, D., M. Proft, and K. D. Entian. 1995. CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 1915–1922.
  • Hill, J. E., A. M. Myers, T. J. Koerner, and A. Tzagoloff. 1986. Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast 2: 163–167.
  • Holyoak, C. D., D. Bracey, P. W. Piper, K. Kuchler, and P. J. Coote. 1999. The Saccharomyces cerevisiae weak-acid-inducible ABC transporter Pdr12 transports fluorescein and preservative anions from the cytosol by an energy-dependent mechanism. J. Bacteriol. 181: 4644–4652.
  • Holyoak, C. D., M. Stratford, Z. McMullin, M. B. Cole, K. Crimmins, A. J. Brown, and P. J. Coote. 1996. Activity of the plasma membrane H+-ATPase and optimal glycolytic flux are required for rapid adaptation and growth of Saccharomyces cerevisiae in the presence of the weak acid preservative sorbic acid. Appl. Environ. Microbiol. 62: 3158–3164.
  • Huang, H. L., and M. C. Brandriss. 2000. The regulator of the yeast proline utilization pathway is differentially phosphorylated in response to the quality of the nitrogen source. Mol. Cell. Biol. 20: 892–899.
  • Kaiser, C., S. Michaelis, and A. Mitchell. 1994. Methods in yeast genetics: a laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Katzmann, D. J., T. C. Hallstrüm, M. Voet, W. Wysock, J. Golin, G. Volckaert, and W. S. Moye-Rowley. 1995. Expression of an ATP-binding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 6875–6883.
  • Kolaczkowski, M., A. Kolaczowska, J. Luczynski, S. Witek, and A. Goffeau. 1998. In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network. Microb. Drug Resist. 4: 143–158.
  • Krebs, H. A., D. Wiggins, M. Stubbs, A. Sols, and F. Bedoya. 1983. Studies on the mechanism of the antifungal action of benzoate. Biochem. J. 214: 657–663.
  • Lohr, D., P. Venkov, and J. Zlatanova. 1995. Transcriptional regulation in the yeast GAL gene family: a complex genetic network. FASEB J. 9: 777–787.
  • Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14: 953–961.
  • Marmorstein, R., M. Carey, M. Ptashne, and S. C. Harrison. 1992. DNA recognition by GAL4: structure of a protein-DNA complex. Nature 356: 408–414.
  • Martinez-Pastor, M. T., G. Marchler, C. Schüller, A. Marchler-Bauer, H. Ruis, and F. Estruch. 1996. The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J. 15: 2227–2235.
  • Pearce, A. K., I. R. Booth, and A. J. Brown. 2001. Genetic manipulation of 6-phosphofructo-1-kinase and fructose 2,6-bisphosphate levels affects the extent to which benzoic acid inhibits the growth of Saccharomyces cerevisiae. Microbiology 147: 403–410.
  • Pfeifer, K., K. S. Kim, S. Kogan, and L. Guarente. 1989. Functional dissection and sequence of yeast HAP1 activator. Cell 56: 291–301.
  • Piper, P., C. O. Calderon, K. Hatzixanthis, and M. Mollapour. 2001. Weak acid adaptation: the stress response that confers yeasts with resistance to organic acid food preservatives. Microbiology 147: 2635–2642.
  • Piper, P., Y. Mahé, S. Thompson, R. Pandjaitan, C. Holyoak, R. Egner, M. Mühlbauer, P. Coote, and K. Kuchler. 1998. The Pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast. EMBO J. 17: 4257–4265.
  • Piper, P. W. 1999. Yeast superoxide dismutase mutants reveal a pro-oxidant action of weak organic acid food preservatives. Free Radic. Biol. Med. 27: 1219–1227.
  • Piper, P. W., C. Ortiz-Calderon, C. Holyoak, P. Coote, and M. Cole. 1997. Hsp30, the integral plasma membrane heat shock protein of Saccharomyces cerevisiae, is a stress-inducible regulator of plasma membrane H+-ATPase. Cell Stress Chaperones 2: 12–24.
  • Rottensteiner, H., A. J. Kal, B. Hamilton, H. Ruis, and H. F. Tabak. 1997. A heterodimer of the Zn2Cys6 transcription factors Pip2p and Oaf1p controls induction of genes encoding peroxisomal proteins in Saccharomyces cerevisiae. Eur. J. Biochem. 247: 776–783.
  • Sadowski, I., C. Costa, and R. Dhanawansa. 1996. Phosphorylation of Ga14p at a single C-terminal residue is necessary for galactose-inducible transcription. Mol. Cell. Biol. 16: 4879–4887.
  • Schjerling, P., and S. Holmberg. 1996. Comparative amino acid sequence analysis of the C6 zinc cluster family of transcriptional regulators. Nucleic Acids Res. 24: 4599–4607.
  • Servos, J., E. Haase, and M. Brendel. 1993. Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases. Mol. Gen. Genet. 236: 214–218.
  • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19–27.
  • Stratford, M., and P. A. Anslow. 1996. Comparison of the inhibitory action on Saccharomyces cerevisiae of weak-acid preservatives, uncouplers, and medium-chain fatty acids. FEMS Microbiol. Lett. 142: 53–58.
  • Sze, J. Y., M. Woontner, J. A. Jaehning, and G. B. Kohlhaw. 1992. In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate. Science 258: 1143–1145.
  • Wach, A., A. Brachat, C. Alberti-Segui, C. Rebischung, and P. Philippsen. 1997. Heterologous HIS3 marker and GFP reporter modules for PCR-targeting in Saccharomyces cerevisiae. Yeast 13: 1065–1075.
  • Wang, D., Y. Hu, F. Zheng, K. Zhou, and G. B. Kohlhaw. 1997. Evidence that intramolecular interactions are involved in masking the activation domain of transcriptional activator Leu3p. J. Biol. Chem. 272: 19383–19392.
  • Watt, R., and P. W. Piper. 1997. UBI4, the polyubiquitin gene of Saccharomyces cerevisiae, is a heat shock gene that is also subject to catabolite derepression control. Mol. Gen. Genet. 253: 439–447.
  • Wolf, S. S., K. Roder, and M. Schweizer. 1996. Construction of a reporter plasmid that allows expression libraries to be exploited for the one-hybrid system. BioTechniques 20: 568–574.
  • Wolfger, H., Y. Mahé, A. Parle-McDermott, A. Delahodde, and K. Kuchler. 1997. The yeast ATP binding cassette (ABC) protein genes PDR10 and PDR15 are novel targets for the Pdr1 and Pdr3 transcriptional regulators. FEBS Lett. 418: 269–274.
  • Wolfger, H., Y. M. Mamnun, and K. Kuchler. 2001. Fungal ABC proteins: pleiotropic drug resistance, stress response and cellular detoxification. Res. Microbiol. 152: 375–389.
  • Zhang, L., and L. Guarente. 1994. The yeast activator HAP1—a GAL4 family member—binds DNA in a directly repeated orientation. Genes Dev. 8: 2110–2119.

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