Clb6/Cdc28 and Cdc14 Regulate Phosphorylation Status and Cellular Localization of Swi6

REFERENCE

• Andrews, B. J., and Moore L. A.. 1992. Interaction of the yeast Swi4 and Swi6 cell cycle regulatory proteins in vitro. Proc. Natl. Acad. Sci. USA 89:11852–11856.
   PubMedGoogle Scholar
• Baetz, K., and Andrews B.. 1999. Regulation of cell cycle transcription factor Swi4 through auto-inhibition of DNA binding. Mol. Cell. Biol. 19:6729–6741.
   PubMedGoogle Scholar
• Bardin, A. J., and Amon A.. 2001. Men and sin: what's the difference? Nat. Rev. Mol. Cell. Biol. 2:815–826.
   PubMedGoogle Scholar
• Basco, R. D., Segal M. D., and Reed S. I.. 1995. Negative regulation of G1 and G2 by S-phase cyclins of Saccharomyces cerevisiae. Mol. Cell. Biol. 15:5030–5042.
   PubMedGoogle Scholar
• Berben, G., Dumont J., Gilliquet V., Bolle P. A., and Hilger F.. 1991. The YDp plasmids: a uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae. Yeast 7:475–477.
   PubMedGoogle Scholar
• Breeden, L., and Mikesell G. E.. 1991. Cell cycle-specific expression of the SWI4 transcription factor is required for the cell cycle regulation of HO transcription. Genes Dev. 5:1183–1190.
   PubMedGoogle Scholar
• Cosma, M. P., Panizza S., and Nasmyth K.. 2001. Cdk1 triggers association of RNA polymerase to cell cycle promoters only after recruitment of the mediator by SBF. Mol. Cell 7:1213–1220.
   PubMed Web of Science ®Google Scholar
• Cross, F. R., and Jacobson M. D.. 2000. Conservation and function of a potential substrate-binding domain in the yeast Clb5 B-type cyclin. Mol. Cell. Biol. 20:4782–4790.
   PubMedGoogle Scholar
• Di Como, C. J., Chang H., and Arndt K. T.. 1995. Activation of CLN1 and CLN2 G1 cyclin gene expression by BCK2. Mol. Cell. Biol. 15:1835–1846.
   PubMedGoogle Scholar
• Dirick, L., Moll T., Auer H., and Nasmyth K.. 1992. A central role for SWI6 in modulating cell cycle Start-specific transcription in yeast. Nature 357:508–513.
   PubMedGoogle Scholar
• Epstein, C. B., and Cross F. R.. 1992. CLB5: a novel B cyclin from budding yeast with a role in S phase. Genes Dev. 6:1695–1706.
   PubMed Web of Science ®Google Scholar
• Epstein, C. B., and Cross F. R.. 1994. Genes that can bypass the CLN requirement for Saccharomyces cerevisiae cell cycle START. Mol. Cell. Biol. 14:2041–2047.
   PubMedGoogle Scholar
• Foord, R., Taylor I. A., Sedgwick S. G., and Smerdon S. J.. 1999. X-ray structural analysis of the yeast cell cycle regulator Swi6 reveals variations of the ankyrin fold and has implications for Swi6 function. Nat. Struct. Biol. 6:157–165.
   PubMedGoogle Scholar
• Hagemeier, C., Bannister A. J., Cook A., and Kouzarides T.. 1993. The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB. Proc. Natl. Acad. Sci. USA 90:1580–1584.
   PubMed Web of Science ®Google Scholar
• Harrington, L. A., and Andrews B. J.. 1996. Binding to the yeast SwI4,6-dependent cell cycle box, CACGAAA, is cell cycle regulated in vivo. Nucleic Acids Res. 24:558–565.
   PubMedGoogle Scholar
• Ho, Y., Costanzo M., Moore L., Kobayashi R., and Andrews B. J.. 1999. Regulation of transcription at the Saccharomyces cerevisiae start transition by Stb1, a Swi6-binding protein. Mol. Cell. Biol. 19:5267–5278.
   PubMed Web of Science ®Google Scholar
• Ho, Y., Mason S., Kobayashi R., Hoekstra M., and Andrews B.. 1997. Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 94:581–586.
   PubMed Web of Science ®Google Scholar
• Horak, C. E., Luscombe N. M., Qian J., Bertone P., Piccirrillo S., Gerstein M., and Snyder M.. 2002. Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev. 16:3017–3033.
   PubMed Web of Science ®Google Scholar
• Kelly, T. J., and Brown G. W.. 2000. Regulation of chromosome replication. Annu. Rev. Biochem. 69:829–880.
   PubMed Web of Science ®Google Scholar
• Koch, C., Moll T., Neuberg M., Ahorn H., and Nasmyth K.. 1993. A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase. Science 261:1551–1557.
   PubMed Web of Science ®Google Scholar
• Koch, C., Schleiffer A., Ammerer G., and Nasmyth K.. 1996. Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2. Genes Dev. 10:129–141.
   PubMed Web of Science ®Google Scholar
• Kuhne, C., and Linder P.. 1993. A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle. EMBO J. 12:3437–3447.
   PubMed Web of Science ®Google Scholar
• Longtine, M. S., McKenzie III A., Demarini D. J., Shah N. G., Wach A., Brachat A., Philippsen P., and Pringle J. R.. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953–961.
   PubMed Web of Science ®Google Scholar
• Lowndes, N. F., Johnson A. L., Breeden L., and Johnston L. H.. 1992. SWI6 protein is required for transcription of the periodically expressed DNA synthesis genes in budding yeast. Nature 357:505–508.
   PubMed Web of Science ®Google Scholar
• Madden, K., Sheu Y. J., Baetz K., Andrews B., and Snyder M.. 1997. SBF cell cycle regulator as a target of the yeast PKC-MAP kinase pathway. Science 275:1781–1784.
   PubMedGoogle Scholar
• Masumoto, H., Muramatsu S., Kamimura Y., and Araki H.. 2002. S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast. Nature 415:651–655.
   PubMed Web of Science ®Google Scholar
• Nasmyth, K. 1996. At the heart of the budding yeast cell cycle. Trends Genet. 12:405–412.
   PubMedGoogle Scholar
• Nasmyth, K., and Dirick L.. 1991. The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell 66:995–1013.
   PubMed Web of Science ®Google Scholar
• Nguyen, V. Q., Co C., and Li J. J.. 2001. Cyclin-dependent kinases prevent DNA rereplication through multiple mechanisms. Nature 411:1068–1073.
   PubMed Web of Science ®Google Scholar
• Noguchi, E., Shanahan P., Noguchi C., and Russell P.. 2002. CDK phosphorylation of Drc1 regulates DNA replication in fission yeast. Curr. Biol. 12:599–605.
   PubMedGoogle Scholar
• Ogas, J., Andrews B. J., and Herskowitz I.. 1991. Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription. Cell 66:1015–1026.
   PubMedGoogle Scholar
• Pereira, G., Manson C., Grindlay J., and Schiebel E.. 2002. Regulation of the Bfa1p-Bub2p complex at spindle pole bodies by the cell cycle phosphatase Cdc14p. J. Cell Biol. 157:367–379.
   PubMed Web of Science ®Google Scholar
• Piatti, S., Lengauer C., and Nasmyth K.. 1995. Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a ‘reductional’ anaphase in the budding yeast Saccharomyces cerevisiae. EMBO J. 14:3788–3799.
   PubMed Web of Science ®Google Scholar
• Primig, M., Sockanathan S., Auer H., and Nasmyth K.. 1992. Anatomy of a transcription factor important for the start of the cell cycle in Saccharomyces cerevisiae. Nature 358:593–597.
   PubMedGoogle Scholar
• Pringle, J. R., Adams A. E., Drubin D. G., and Haarer B. K.. 1991. Immunofluorescence methods for yeast. Methods Enzymol. 194:565–602.
   PubMedGoogle Scholar
• Queralt, E., and Igual J. C.. 2003. Cell cycle activation of the Swi6p transcription factor is linked to nucleocytoplasmic shuttling. Mol. Cell. Biol. 23:3126–3140.
   PubMed Web of Science ®Google Scholar
• Reed, S. I., Hadwiger J. A., and Lorincz A. T.. 1985. Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28. Proc. Natl. Acad. Sci. USA 82:4055–4059.
   PubMed Web of Science ®Google Scholar
• Reed, S. I., and Wittenberg C.. 1990. Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 87:5697–5701.
   PubMedGoogle Scholar
• Reynard, G. J., Reynolds W., Verma R., and Deshaies R. J.. 2000. Cks1 is required for G1 cyclin-cyclin-dependent kinase activity in budding yeast. Mol. Cell. Biol. 20:5858–5864.
   PubMed Web of Science ®Google Scholar
• Russo, A. A., Jeffrey P. D., Patten A. K., Massague J., and Pavletich N. P.. 1996. Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature 382:325–331.
   PubMed Web of Science ®Google Scholar
• Schneider, B. L., Yang Q. H., and Futcher A. B.. 1996. Linkage of replication to start by the Cdk inhibitor Sic1. Science 272:560–562.
   PubMed Web of Science ®Google Scholar
• Schwob, E., and Nasmyth K.. 1993. CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes Dev. 7:1160–1175.
   PubMed Web of Science ®Google Scholar
• Sedgwick, S. G., and Smerdon S. J.. 1999. The ankyrin repeat: a diversity of interactions on a common structural framework. Trends Biochem. Sci. 24:311–316.
   PubMed Web of Science ®Google Scholar
• Sedgwick, S. G., Taylor I. A., Adam A. C., Spanos A., Howell S., Morgan B. A., Treiber M. K., Kanuga N., Banks G. R., Foord R., and Smerdon S. J.. 1998. Structural and functional architecture of the yeast cell cycle-transcription factor swi6. J. Mol. Biol. 281:763–775.
   PubMed Web of Science ®Google Scholar
• Sidorova, J. M., and Breeden L. L.. 1997. Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae. Genes Dev. 11:3032–3045.
   PubMedGoogle Scholar
• Sidorova, J. M., Mikesell G. E., and Breeden L. L.. 1995. Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization. Mol. Biol. Cell 6:1641–1658.
   PubMedGoogle Scholar
• Siegmund, R. F., and Nasmyth K. A.. 1996. The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6. Mol. Cell. Biol. 16:2647–2655.
   PubMedGoogle Scholar
• Spellman, P. T., Sherlock G., Zhang M. Q., Iyer V. R., Anders K., Eisen M. B., Brown P. O., Botstein D., and Futcher B.. 1998. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol. Biol. Cell 9:3273–3297.
   PubMed Web of Science ®Google Scholar
• Stegmeier, F., Visintin R., and Amon A.. 2002. Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase. Cell 108:207–220.
   PubMed Web of Science ®Google Scholar
• Stuart, D., and Wittenberg C.. 1995. CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cells. Genes Dev. 9:2780–2794.
   PubMedGoogle Scholar
• Taba, M. R., Muroff I., Lydall D., Tebb G., and Nasmyth K.. 1991. Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast. Genes Dev. 5:2000–2013.
   PubMedGoogle Scholar
• Thuret, J. Y., Valay J. G., Faye G., and Mann C.. 1996. Civ1 (CAK in vivo), a novel Cdk-activating kinase. Cell 86:565–576.
   PubMed Web of Science ®Google Scholar
• Tyers, M., Tokiwa G., and Futcher B.. 1993. Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. EMBO J. 12:1955–1968.
   PubMed Web of Science ®Google Scholar
• Ubersax, J. A., Woodbury E. L., Quang P. N., Paraz M., Blethrow J. D., Shah K., Shokat K. M., and Morgan D. O.. 2003. Targets of the cyclin-dependent kinase Cdk1. Nature 425:859–864.
   PubMed Web of Science ®Google Scholar
• Verma, R., Annan R. S., Huddleston M. J., Carr S. A., Reynard G., and Deshaies R. J.. 1997. Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase. Science 278:455–460.
   PubMed Web of Science ®Google Scholar
• Visintin, R., Craig K., Hwang E. S., Prinz S., Tyers M., and Amon A.. 1998. The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol. Cell 2:709–718.
   PubMed Web of Science ®Google Scholar
• Wijnen, H., and Futcher B.. 1999. Genetic analysis of the shared role of CLN3 and BCK2 at the G(1)-S transition in Saccharomyces cerevisiae. Genetics 153:1131–1143.
   PubMedGoogle Scholar
• Wijnen, H., Landman A., and Futcher B.. 2002. The G1 cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6. Mol. Cell. Biol. 22:4402–4418.
   PubMed Web of Science ®Google Scholar
• Wittenberg, C., and Reed S. I.. 1988. Control of the yeast cell cycle is associated with assembly/disassembly of the Cdc28 protein kinase complex. Cell 54:1061–1072.
   PubMedGoogle Scholar
• Zhu, H., Klemic J. F., Chang S., Bertone P., Casamayor A., Klemic K. G., Smith D., Gerstein M., Reed M. A., and Snyder M.. 2000. Analysis of yeast protein kinases with protein chips. Nat. Genet. 26:283–289.
   PubMed Web of Science ®Google Scholar
• Zou, L., and Stillman B.. 2000. Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Mol. Cell. Biol. 20:3086–3096.
   PubMed Web of Science ®Google Scholar