Enhancement of Sleeping Beauty Transposition by CpG Methylation: Possible Role of Heterochromatin Formation

REFERENCES

• Bellen, H. J., O'Kane C. J., Wilson C., Grossniklaus U., Pearson R. K., and Gehring W. J.. 1989. P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev. 3:1288–1300.
   PubMed Web of Science ®Google Scholar
• Bird, A. 2001. Molecular biology. Methylation talk between histones and DNA. Science 294:2113–2115.
   PubMed Web of Science ®Google Scholar
• Carlson, C. M., Dupuy A. J., Fritz S., Roberg-Perez K. J., Fletcher C. F., and Largaespada D. A.. 2003. Transposon mutagenesis of the mouse germline. Genetics 165:243–256.
   PubMed Web of Science ®Google Scholar
• Cui, Z., Geurts A. M., Liu G., Kaufman C. D., and Hackett P. B.. 2002. Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon. J. Mol. Biol. 318:1221–1235.
   PubMed Web of Science ®Google Scholar
• Dhar, V., Skoultchi A. I., and Schildkraut C. L.. 1989. Activation and repression of a beta-globin gene in cell hybrids is accompanied by a shift in its temporal replication. Mol. Cell. Biol. 9:3524–3532.
   PubMedGoogle Scholar
• Dupuy, A. J., Clark K., Carlson C. M., Fritz S., Davidson A. E., Markley K. M., Finley K., Fletcher C. F., Ekker S. C., Hackett P. B., Horn S., and Largaespada D. A.. 2002. Mammalian germ-line transgenesis by transposition. Proc. Natl. Acad. Sci. USA 99:4495–4499.
   PubMed Web of Science ®Google Scholar
• Dupuy, A. J., Fritz S., and Largaespada D. A.. 2001. Transposition and gene disruption in the male germline of the mouse. Genesis 30:82–88.
   PubMed Web of Science ®Google Scholar
• Feng, Y. Q., Lorincz M. C., Fiering S., Greally J. M., and Bouhassira E. E.. 2001. Position effects are influenced by the orientation of a transgene with respect to flanking chromatin. Mol. Cell. Biol. 21:298–309.
   PubMedGoogle Scholar
• Fischer, S. E., van Luenen H. G., and Plasterk R. H.. 1999. Cis requirements for transposition of Tc1-like transposons in C. elegans. Mol. Gen. Genet. 262:268–274.
   PubMedGoogle Scholar
• Fischer, S. E., Wienholds E., and Plasterk R. H.. 2001. Regulated transposition of a fish transposon in the mouse germ line. Proc. Natl. Acad. Sci. USA 98:6759–6764.
   PubMed Web of Science ®Google Scholar
• Friedrich, G., and Soriano P.. 1991. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5:1513–1523.
   PubMed Web of Science ®Google Scholar
• Geurts, A. M., Yang Y., Clark K. J., Liu G., Cui Z., Dupuy A. J., Bell J. B., Largaespada D. A., and Hackett P. B.. 2003. Gene transfer into genomes of human cells by the sleeping beauty transposon system. Mol. Ther. 8:108–117.
   PubMed Web of Science ®Google Scholar
• Greenwald, I. 1985. lin-12, a nematode homeotic gene, is homologous to a set of mammalian proteins that includes epidermal growth factor. Cell 43:583–590.
   PubMed Web of Science ®Google Scholar
• Grewal, S. I., and Elgin S. C.. 2002. Heterochromatin: new possibilities for the inheritance of structure. Curr. Opin. Genet. Dev. 12:178–187.
   PubMed Web of Science ®Google Scholar
• Hirochika, H., Okamoto H., and Kakutani T.. 2000. Silencing of retrotransposons in arabidopsis and reactivation by the ddm1 mutation. Plant Cell 12:357–369.
   PubMed Web of Science ®Google Scholar
• Horie, K., Kuroiwa A., Ikawa M., Okabe M., Kondoh G., Matsuda Y., and Takeda J.. 2001. Efficient chromosomal transposition of a Tc1/mariner-like transposon Sleeping Beauty in mice. Proc. Natl. Acad. Sci. USA 98:9191–9196.
   PubMed Web of Science ®Google Scholar
• Horie, K., Yusa K., Yae K., Odajima J., Fischer S. E., Keng V. W., Hayakawa T., Mizuno S., Kondoh G., Ijiri T., Matsuda Y., Plasterk R. H., and Takeda J.. 2003. Characterization of Sleeping Beauty transposition and its application to genetic screening in mice. Mol. Cell. Biol. 23:9189–9207.
   PubMed Web of Science ®Google Scholar
• Hrabe de Angelis, M. H., H. Flaswinkel, H. Fuchs, B. Rathkolb, D. Soewarto, S. Marschall, S. Heffner, W. Pargent, K. Wuensch, M. Jung, A. Reis, T. Richter, F. Alessandrini, T. Jakob, E. Fuchs, H. Kolb, E. Kremmer, K. Schaeble, B. Rollinski, A. Roscher, C. Peters, T. Meitinger, T. Strom, T. Steckler, F. Holsboer, T. Klopstock, F. Gekeler, C. Schindewolf, T. Jung, K. Avraham, H. Behrendt, J. Ring, A. Zimmer, K. Schughart, K. Pfeffer, E. Wolf, and R. Balling. 2000. Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat. Genet. 25:444–447.
   PubMed Web of Science ®Google Scholar
• Ivics, Z., Hackett P. B., Plasterk R. H., and Izsvak Z.. 1997. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 91:501–510.
   PubMed Web of Science ®Google Scholar
• Izsvak, Z., Ivics Z., and Plasterk R. H.. 2000. Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates. J. Mol. Biol. 302:93–102.
   PubMed Web of Science ®Google Scholar
• Izsvak, Z., Khare D., Behlke J., Heinemann U., Plasterk R. H., and Ivics Z.. 2002. Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition. J. Biol. Chem. 277:34581–34588.
   PubMed Web of Science ®Google Scholar
• Ketting, R. F., Haverkamp T. H., van Luenen H. G., and Plasterk R. H.. 1999. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99:133–141.
   PubMed Web of Science ®Google Scholar
• Lavoie, B. D., and Chaconas G.. 1990. Immunoelectron microscopic analysis of the A, B, and HU protein content of bacteriophage Mu transpososomes. J. Biol. Chem. 265:1623–1627.
   PubMedGoogle Scholar
• Li, E. 2002. Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet. 3:662–673.
   PubMed Web of Science ®Google Scholar
• Luo, G., Ivics Z., Izsvak Z., and Bradley A.. 1998. Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA 95:10769–10773.
   PubMed Web of Science ®Google Scholar
• Miura, A., Yonebayashi S., Watanabe K., Toyama T., Shimada H., and Kakutani T.. 2001. Mobilization of transposons by a mutation abolishing full DNA methylation in Arabidopsis. Nature 411:212–214.
   PubMedGoogle Scholar
• Moerman, D. G., Benian G. M., and Waterston R. H.. 1986. Molecular cloning of the muscle gene unc-22 in Caenorhabditis elegans by Tc1 transposon tagging. Proc. Natl. Acad. Sci. USA 83:2579–2583.
   PubMedGoogle Scholar
• Muro, Y., Masumoto H., Yoda K., Nozaki N., Ohashi M., and Okazaki T.. 1992. Centromere protein B assembles human centromeric alpha-satellite DNA at the 17-bp sequence, CENP-B box. J. Cell Biol. 116:585–596.
   PubMedGoogle Scholar
• Nolan, P. M., Peters J., Strivens M., Rogers D., Hagan J., Spurr N., Gray I. C., Vizor L., Brooker D., Whitehill E., Washbourne R., Hough T., Greenaway S., Hewitt M., Liu X., McCormack S., Pickford K., Selley R., Wells C., Tymowska-Lalanne Z., Roby P., Glenister P., Thornton C., Thaung C., Stevenson J. A., Arkell R., Mburu P., Hardisty R., Kiernan A., Erven A., Steel K. P., Voegeling S., Guenet J. L., Nickols C., Sadri R., Nasse M., Isaacs A., Davies K., Browne M., Fisher E. M., Martin J., Rastan S., Brown S. D., and Hunter J.. 2000. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat. Genet. 25:440–443.
   PubMed Web of Science ®Google Scholar
• Osborne, B. I., and Baker B.. 1995. Movers and shakers: maize transposons as tools for analyzing other plant genomes. Curr. Opin. Cell Biol. 7:406–413.
   PubMed Web of Science ®Google Scholar
• Schubeler, D., Francastel C., Cimbora D. M., Reik A., Martin D. I., and Groudine M.. 2000. Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human beta-globin locus. Genes Dev. 14:940–950.
   PubMed Web of Science ®Google Scholar
• Schubeler, D., Lorincz M. C., Cimbora D. M., Telling A., Feng Y. Q., Bouhassira E. E., and Groudine M.. 2000. Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylation. Mol. Cell. Biol. 20:9103–9112.
   PubMed Web of Science ®Google Scholar
• Spradling, A. C., Stern D. M., Kiss I., Roote J., Laverty T., and Rubin G. M.. 1995. Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl. Acad. Sci. USA 92:10824–10830.
   PubMed Web of Science ®Google Scholar
• Tabara, H., Sarkissian M., Kelly W. G., Fleenor J., Grishok A., Timmons L., Fire A., and Mello C. C.. 1999. The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99:123–132.
   PubMed Web of Science ®Google Scholar
• Walsh, C. P., Chaillet J. R., and Bestor T. H.. 1998. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat. Genet. 20:116–117.
   PubMed Web of Science ®Google Scholar
• Waterston, R. H., Lindblad-Toh K., Birney E., Rogers J., et al. 2002. Initial sequencing and comparative analysis of the mouse genome. Nature 420:520–562.
   PubMed Web of Science ®Google Scholar
• Wu-Scharf, D., B. Jeong, C. Zhang, and H. Cerutti. 2000. Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-box RNA helicase. Science 290:1159–1162.
   PubMed Web of Science ®Google Scholar
• Yant, S. R., Ehrhardt A., Mikkelsen J. G., Meuse L., Pham T., and Kay M. A.. 2002. Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo. Nat. Biotechnol. 20:999–1005.
   PubMed Web of Science ®Google Scholar
• Yant, S. R., Meuse L., Chiu W., Ivics Z., Izsvak Z., and Kay M. A.. 2000. Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. Nat. Genet. 25:35–41.
   PubMed Web of Science ®Google Scholar
• Yoda, K., Kitagawa K., Masumoto H., Muro Y., and Okazaki T.. 1992. A human centromere protein, CENP-B, has a DNA binding domain containing four potential alpha helices at the NH2 terminus, which is separable from dimerizing activity. J. Cell Biol. 119:1413–1427.
   PubMed Web of Science ®Google Scholar
• Yu, F., Zingler N., Schumann G., and Stratling W. H.. 2001. Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription. Nucleic Acids Res. 29:4493–4501.
   PubMed Web of Science ®Google Scholar
• Zayed, H., Izsvak Z., Khare D., Heinemann U., and Ivics Z.. 2003. The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition. Nucleic Acids Res. 31:2313–2322.
   PubMed Web of Science ®Google Scholar