39
Views
54
CrossRef citations to date
0
Altmetric
Gene Expression

A Novel Variant of Inpp5f Is Imprinted in Brain, and Its Expression Is Correlated with Differential Methylation of an Internal CpG Island

, , , , , , , & show all
Pages 5514-5522 | Received 20 Jan 2005, Accepted 23 Mar 2005, Published online: 27 Mar 2023

REFERENCES

  • Arai, Y., T. Ijuin, M. Itoh, T. Takenawa, S. Takashima, and L. E. Becker. 2001. Developmental changes of synaptojanin expression in the human cerebrum and cerebellum. Dev. Brain Res. 129:1–9.
  • Barlow, D. P. 1995. Gametic imprinting in mammals. Science 270:1610–1613.
  • Beechey, C. V., B. M. Cattanach, and R. L. Selley. 2000. Standard ideogram/anomaly breakpoints of the Mouse MRC Mammalian Genetics Unit, Harwell, Oxfordshire, United Kingdom. [Online.] http://www.mgu.har.mrc.ac.uk/imprinting/implink.html.
  • Bell, A. C., and G. Felsenfeld. 2000. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 405:482–485.
  • Blagitko, N., S. Mergenthaler, U. Schulz, H. A. Wollmann, W. Craigen, T. Eggermann, H. H. Ropers, and V. M. Kalscheuer. 2000. Human GRB10 is imprinted and expressed from the paternal and maternal allele in a highly tissue- and isoform-specific fashion. Hum. Mol. Genet. 9:1587–1595.
  • Brudno, M., C. B. Do, G. M. Cooper, M. F. Kim, E. Davydov, E. D. Green, A. Sidow, and S. Batzoglou. 2003. NISC Comparative Sequencing Program LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA. Genome Res. 13:721–731.
  • Choi, J. D., L. A. Underkoffler, J. C. Collins, S. M. Marcheginani, N. A. Terry, C. V. Beechey, and R. J. Oakey. 2001. Microarray expression profiling of tissues from mice with uniparental duplications of chromosomes 7 and 11 to identify imprinted genes. Mammalian Genome 12:758–764.
  • Clark, S. J., J. Harrison, C. L. Paul, and M. Frommer. 1994. High sensitivity mapping of methylated cytosines. Nucleic Acids Res. 22:2990–2997.
  • Constancia, M., B. Pickard, G. Kelsey, and W. Reik. 1999. Imprinting mechanisms. Genome Res. 8:881–900.
  • Couronne, O., A. Poliakov, N. Bray, T. Ishkhanov, D. Ryaboy, E. Rubin, L. Pachter, and I. Dubchak. 2003. Strategies and tools for whole-genome alignments. Genome Res. 13:73–80.
  • Dallosso, A. R., A. L. Hancock, K. W. Brown, A. C. Williams, S. Jackson, and K. Malik. 2003. Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours. Hum. Mol. Genet. 13:405–415.
  • DeChiara, T. M., E. J. Robertson, and A. Efstratiadis. 1991. Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64:849–859.
  • Guillemot, F., T. Caspary, S. M. Tilghman, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, D. J. Anderson, A. L. Joyner, J. Rossant, and A. Nagy. 1995. Genomic imprinting of Mash2, a mouse gene required for trophoblast development. Nat. Genet. 9:235–241.
  • Hark, A. T., C. J. Schoenherr, D. J. Katz, R. S. Ingram, J. M. Levorse, and S. M. Tilghman. 2000. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature 405:486–489.
  • Kantor, B., Y. Kaufman, K. Makedonski, A. Razin, and R. Shemer. 2004. Establishing the epigenetic status of the Prader-Willi/Angelman imprinting center in the gametes and embryo. Hum. Mol. Genet. 13:2767–2779.
  • Kobayashi, S., H. Wagatsuma, R. Ono, H. Ichikawa, M. Yamazaki, H. Tashiro, K. Aisaka, N. Miyoshi, T. Kohda, A. Ogura, M. Ohki, T. Kaneko-Ishino, and F. Ishino. 2000. Mouse Peg9/Dlk1 and human PEG9/DLK1 are paternally expressed imprinted genes closely located to the maternally expressed imprinted genes: mouse Meg3/Gtl2 and human. MEG3. Genes Cells 5:1029–1037.
  • Lau, J. C. Y., M. L. Hanel, and R. Wevrick. 2004. Tissue-specific and imprinted epigenetic modifications of the human NDN gene. Nucleic Acids Res. 32:3376–3382.
  • Liu, J., S. Yu, D. Litman, W. Chen, and L. S. Weinstein. 2000. Identification of a methylation imprint mark within the mouse Gnas locus. Mol. Cell. Biol. 20:5808–5817.
  • Minagawa, T., T. Ijuin, Y. Mochizuki, and T. Takenawa. 2001. Identification and characterization of a Sac domain-containing phosphoinositide 5-phosphatase. J. Biol. Chem. 276:22011–22015.
  • Mizuno, Y., Y. Sotomaru, Y. Katsuzawa, T. Kono, M. Meguro, M. Oshimuru, J. Kawai, Y. Tomaru, H. Kiyosawa, I. Nikaido, H. Amanuma, Y. Hayashizaki, and Y. Okazaki. 2002. Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray. Biochem. Biophys. Res. Commun. 290:1499–1505.
  • Modrek, B., and C. J. Lee. 2003. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat. Genet. 34:177–180.
  • Morison, I. M., C. J. Paton, and S. D. Cleverley. 2001. The imprinted gene and parent of origin effect database. Nucleic Acids Res. 29:275–276.
  • Nikaido, I., C. Saito, Y. Mizuno, M. Meguro, H. Bono, M. Kadomura, T. Kono, G. A. Morris, P. A. Lyons, M. Oshimura, Y. Hayashizaki, Y. Okazaki, et al. 2003. Discovery of imprinted transcripts in the mouse transcriptome using large-scale expression profiling. Genome Res. 13(Suppl. 6B):1402–1409.
  • Paulsen, M., O. El-Maarri, S. Engemann, M. Strodicke, O. Franck, K. Davies, R. Reinhardt, W. Reik, and J. Walter. 2000. Sequence conservation and variability of imprinting in Beckwith-Wiedemann syndrome gene cluster in human and mouse. Hum. Mol. Genet. 9:1829–1841.
  • Paulsen, M., S. Takada, N. A. Youngson, M. Bebnchaib, C. Charlier, K. Segers, M. Georges, and A. C. Ferguson-Smith. 2001. Comparative sequence analysis of the imprinted Dlk1-Gtl2 locus in three mammalian species reveals highly conserved genomic elements and refines comparison with the Igf2-H19 region. Genome Res. 11:2085–2094.
  • Peters, J., S. F. Wroe, C. A. Wells, H. J. Miller, D. Bodle, C. V. Beechey, C. M. Williamson, and G. Kelsey. 1999. A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2. Proc. Natl. Acad. Sci. USA 96:3830–3835.
  • Reik, W., and J. Walter. 2001. Genomic imprinting: parental influence on the genome. Nat. Rev. Genet. 2:21–32.
  • Reik, W., and J. Walter. 1998. Imprinting mechanisms in mammals. Curr. Opin. Genet. Dev. 8:154–164.
  • Sassoon, D., and N. Rosenthal. 1993. Detection of messenger RNA by in situ hybridization, p. 384–406. In P. M. Wassarman and M. L. DePamphilis (ed.), Methods in enzymology. Academic Press, London, England.
  • Schoenherr, C. J., J. M. Levorse, and S. M. Tilghman. 2003. CTCF maintains differential methylation at the Igf2/H19 locus. Nature Genetics 33:66–69.
  • Smilinich, N. J., C. D. Day, G. V. Fitzpatrick, G. M. Caldwell, A. C. Lossie, P. R. Cooper, A. C. Smallwood, J. A. Joyce, P. N. Schofield, W. Reik, R. D. Nicholls, R. Weksberg, D. J. Driscoll, E. R. Maher, T. D. Shows, and M. J. Higgins. 1999. A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome. Proc. Natl. Acad. Sci. USA 96:8064–8069.
  • Surani, M. A., S. C. Barton, and M. L. Norris. 1986. Nuclear transplantation in the mouse: heritable differences between parental genomes after activation of the embryonic genome. Cell 45:127–136.
  • Szabo, P., S. H. Tang, Rentsendorj. A., G. P. Pfeifer, and J. R. Mann. 2000. Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Curr. Biol. 18:607–610.
  • Takada, S., M. Paulson, M. Trevendale, C.-E. Tsai, G. Kelsey, B. M. Cattanach, and A. C. Ferguson-Smith. 2002. Epigenetic analysis of the Dlk-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparisons with Igf2-H19. Hum. Mol. Genet. 11:77–86.
  • Thorvaldson, J., J. L. Duran, and M. S. Bartolomei. 1998. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev. 12:3693–3702.
  • Tremblay, K. D., J. R. Saam, R. S. Ingram, S. M. Tilghman, and M. S. Bartolomei. 1995. A paternal specific methylation imprint marks the alleles of the mouse H19 gene. Nat. Genet. 9:407–413.
  • Wilkins, A. S. 1993. Genetic analysis of animal development, 2nd ed. Wiley-Liss, New York, N.Y.
  • Wilkinson, D. G., and M. A. Nieto. 1993. Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts, p. 361–372. In P. M. Wassarman and M. L. DePamphilis (ed.), Methods in enzymology. Academic Press, London, England.
  • Wroe, S. F., G. Kelsey, J. A. Skinner, D. Bodle, S. T. Ball, C. V. Beechey, J. Peters, and C. M. Williamson. 2000. An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus. Proc. Natl. Acad. Sci. USA 97:3342–3346.
  • Wutz, A., O. W. Smrzka, N. Schweifer, K. Schellander, E. F. Wagner, and D. P. Barlow. 1997. Imprinted expression of the Igf2r gene depends on an intronic CpG island. Nature 389:745–749.
  • Wylie, A. A., S. K. Murphy, T. C. Orton, and R. L. Jirtle. 2000. Novel imprinted DLJ1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation. Genome Res. 10:1711–1718.
  • Yoon, B. J., H. Herman, A. Sikora, L. T. Smith, C. Plass, and P. D. Soloway. 2002. Regulation of DNA methylation of Rasgrf1. Nat. Genet. 30:92–96.
  • Zavolan, M., S. Kondo, C. Schonbach, J. Adachi, D. A. Hume, Y. Hayashizaki, T. Gaasterland, et al. 2003. Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome. Genome Res. 13(Suppl. 6B):1290–1300.
  • Zhang, T., P. Haws, and Q. Wu. 2004. Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation. Genome Res. 14:79–89.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.