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Mammalian Genetic Models with Minimal or Complex Phenotypes

Generation and Characterization of Mice Lacking the Zinc Uptake Transporter ZIP3

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Pages 5607-5615 | Received 24 Jan 2005, Accepted 30 Mar 2005, Published online: 27 Mar 2023

REFERENCES

  • Andrews, G. K. 1990. Regulation of metallothionein gene expression. Prog. Food Nutr. Sci. 14:193–258.
  • Andrews, G. K., and J. Geiser. 1999. Expression of metallothionein-I and -II genes provides a reproductive advantage during maternal dietary zinc deficiency. J. Nutr. 129:1643–1648.
  • Andrews, G. K., H. Wang, S. K. Dey, and R. D. Palmiter. 2004. The mouse zinc transporter 1 gene provides an essential function during early embryonic development. Genesis 40:74–81.
  • Apgar, J. 1985. Zinc and reproduction. Annu. Rev. Nutr. 5:43–68.
  • Baudon, J. J., J. L. Fontaine, M. Larregue, G. Feldmann, and R. Laplane. 1978. Acrodermatitis enteropathica. Anatomo-clinical study of 2 familial cases treated with zinc sulfate. Arch. Fr. Pediatr. 35:63–73.
  • Berg, J. M., and Y. G. Shi. 1996. The galvanization of biology: A growing appreciation for the roles of zinc. Science 271:1081–1085.
  • Bohane, T. D., E. Cutz, J. R. Hamilton, and D. G. Gall. 1977. Acrodermatitis enteropathica, zinc, and the Paneth cell. A case report with family studies. Gastroenterology 73:587–592.
  • Cole, T. B., C. A. Robbins, H. J. Wenzel, P. A. Schwartzkroin, and R. D. Palmiter. 2000. Seizures and neuronal damage in mice lacking vesicular zinc. Epilepsy Res. 39:153–169.
  • Cook Mills, J. M., and P. J. Fraker. 1993. Functional capacity of the residual lymphocytes from zinc-deficient adult mice. Br. J. Nutr. 69:835–848.
  • Coyle, P., J. C. Philcox, L. C. Carey, and A. M. Rofe. 2002. Metallothionein: the multipurpose protein. Cell. Mol. Life Sci. 59:627–647.
  • Dalton, T. P., K. Fu, R. D. Palmiter, and G. K. Andrews. 1996. Transgenic mice that over-express metallothionein-I resist dietary zinc deficiency. J. Nutr. 126:825–833.
  • Dalton, T. P., R. D. Palmiter, and G. K. Andrews. 1994. Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res. 22:5016–5023.
  • Dufner-Beattie, J., Y. M. Kuo, J. Gitschier, and G. K. Andrews. 2004. The adaptive response to dietary zinc in mice involves the differential cellular localization and zinc-regulation of the zinc transporters ZIP4 and ZIP5. J. Biol. Chem. 279:49082–49090.
  • Dufner-Beattie, J., S. J. Langmade, F. Wang, D. Eide, and G. K. Andrews. 2003. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem. 278:50142–50150.
  • Dufner-Beattie, J., F. Wang, Y. M. Kuo, J. Gitschier, D. Eide, and G. K. Andrews. 2003. The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. J. Biol. Chem. 278:33474–33481.
  • Eide, D. 1997. Molecular biology of iron and zinc uptake in eukaryotes. Curr. Opin. Cell Biol. 9:573–577.
  • Fraker, P. J., and L. E. King. 2004. Reprogramming of the immune system during zinc deficiency. Annu. Rev. Nutr. 24:277–298.
  • Fraker, P. J., L. E. King, T. Laakko, and T. L. Vollmer. The dynamic link between the integrity of the immune system and zinc status. J. Nutr. 130:1399S–1406S, 2000.
  • Godwin, A. R., H. S. Stadler, K. Nakamura, and M. R. Capecchi. 1998. Detection of targeted GFP-Hox gene fusions during mouse embryogenesis. Proc. Natl. Acad. Sci. USA 95:13042–13047.
  • Guerinot, M. L. 2000. The ZIP family of metal transporters. Biochim. Biophys. Acta 1465:190–198.
  • Hambidge, M., and N. F. Krebs. 2001. Interrelationships of key variables of human zinc homeostasis: Relevance to dietary zinc requirements. Annu. Rev. Nutr. 21:429–452.
  • Harris, E. D. 2002. Cellular transporters for zinc. Nutr. Rev. 60:121–124.
  • Huang, L., C. P. Kirschke, and J. Gitschier. 2002. Functional characterization of a novel mammalian zinc transporter, ZnT6. J. Biol. Chem. 277:26389–26395.
  • Huang, L. P., and J. Gitschier. 1997. A novel gene involved in zinc transport is deficient in the lethal milk mouse. Nat. Genet. 17:292–297.
  • Huang, Z. L., and P. J. Fraker. 2003. Chronic consumption of a moderately low protein diet does not alter hematopoietic processes in young adult mice. J. Nutr. 133:1403–1408.
  • Inoue, K., K. Matsuda, M. Itoh, H. Kawaguchi, H. Tomoike, T. Aoyagi, R. Nagai, M. Hori, Y. Nakamura, and T. Tanaka. 2002. Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. Hum. Mol. Genet. 11:1775–1784.
  • Kambe, T., Y. Yamaguchi-Iwai, R. Sasaki, and M. Nagao. 2004. Overview of mammalian zinc transporters. Cell. Mol. Life Sci. 61:49–68.
  • Kelleher, S. L., and B. Lonnerdal. 2003. Zn transporter levels and localization change throughout lactation in rat mammary gland and are regulated by Zn in mammary cells. J. Nutr. 133:3378–3385.
  • Kelleher, S. L., and B. Lonnerdal. 2005. Zip3 plays a major role in zinc uptake into mammary epithelial cells and is regulated by prolactin. Am. J. Physiol. Cell. Physiol. 288:1042–1047.
  • Kim, B. E., F. D. Wang, J. Dufner-Beattie, G. K. Andrews, D. J. Eide, and M. J. Petris. 2004. Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane. J. Biol. Chem. 279:4523–4530.
  • King, J. C., D. M. Shames, and L. R. Woodhouse. 2000. Zinc homeostasis in humans. J. Nutr. 130(Suppl.):1360S–1366S.
  • King, L. E., and P. J. Fraker. 2002. Zinc deficiency in mice alters myelopoiesis and hematopoiesis. J. Nutr. 132:3301–3307.
  • Krieger, I., G. W. Evans, and P. S. Zelkowitz. 1982. Zinc dependency as a cause of chronic diarrhea in variant acrodermatitis enteropathica. Pediatrics 69:773–777.
  • Krishna, S. S., I. Majumdar, and N. V. Grishin. 2003. Structural classification of zinc fingers. Nucleic Acids Res. 31:532–550.
  • Lamar, E. E., and E. Palmer. 1984. Y-encoded, species-specific DNA in mice: evidence that the Y chromosome exists in two polymorphic forms in inbred strains. Cell 37:171–177.
  • Langmade, S. J., R. Ravindra, P. J. Daniels, and G. K. Andrews. 2000. The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene. J. Biol. Chem. 275:34803–34809.
  • Larregue, M., J. J. Baudon, J. L. Fontaine, G. Feldmann, and R. Laplane. 1977. Acrodermatitis enteropathica: zinc sulfate therapy. Ann. Dermatol. Venereol. 104:737–744.
  • Lee, D. K., J. Geiser, J. Dufner-Beattie, and G. K. Andrews. 2003. Pancreatic metallothionein-l may play a role in zinc homeostasis during maternal dietary zinc deficiency in mice. J. Nutr. 133:45–50.
  • Liuzzi, J. P., R. K. Blanchard, and R. J. Cousins. 2001. Differential regulation of zinc transporter 1, 2, and 4 mRNA expression by dietary zinc in rats. J. Nutr. 131:46–52.
  • Liuzzi, J. P., and R. J. Cousins. 2004. Mammalian zinc transporters. Annu. Rev. Nutr. 24:151–172.
  • Mathews, W. R., F. Wang, D. J. Eide, and M. Van Doren. 2005. Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J. Biol. Chem. 280:787–795.
  • McClain, C. J. 1990. The pancreas and zinc homeostasis. J. Lab. Clin. Med. 116:275–276.
  • Ohlsson, A. 1981. Acrodermatitis enteropathica Reversibility of cerebral atrophy with zinc therapy. Acta Paediatr. Scand. 70:269–273.
  • Taylor, K. M., and R. I. Nicholson. 2003. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta 1611:16–30.
  • Thomas, K. R., and M. R. Capecchi. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51:503–512.
  • Vallee, B. L., and D. S. Auld. 1990. Zinc coordination, function, and structure of zinc enzymes and other proteins. Biochemistry 29:5647–5659.
  • Wang, F., J. Dufner-Beattie, B. E. Kim, M. J. Petris, G. Andrews, and D. J. Eide. 2004. Zinc-stimulated endocytosis controls activity of the mouse ZIP1 and ZIP3 zinc uptake transporters. J. Biol. Chem. 279:24631–24639.
  • Wang, F., B. E. Kim, M. J. Petris, and D. J. Eide. 2004. The mouse ZIP5 protein functions as a zinc transporter and localizes to the basolateral surface of polarized cells. J. Biol. Chem. 279:51433–51441.
  • Yamashita, S., C. Miyagi, T. Fukada, N. Kagara, Y. S. Che, and T. Hirano. 2004. Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer. Nature 429:298–302.

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