11
Views
50
CrossRef citations to date
0
Altmetric
Gene Expression

Mutations in the RNA Polymerase III Subunit Rpc11p That Decrease RNA 3′ Cleavage Activity Increase 3′-Terminal Oligo(U) Length and La-Dependent tRNA Processing

, , , &
Pages 621-636 | Received 23 Aug 2004, Accepted 15 Oct 2004, Published online: 27 Mar 2023

REFERENCES

  • Anderson, J., L. Phan, R. Cuesta, B. A. Carlson, M. Pak, K. Asano, G. R. Bjork, M. Tamame, and A. G. Hinnebusch. 1998. The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Genes Dev. 12:3650–3662.
  • Atwood, A., J. Choi, and H. L. Levin. 1998. The application of a homologous recombination assay revealed amino acid residues in an LTR-retrotransposon that were critical for integration. J. Virol. 72:1324–1333.
  • Bobkova, E. V., N. Habib, G. Alexander, and B. D. Hall. 1999. Mutational analysis of the hydrolytic activity of yeast RNA polymerase III. J. Biol. Chem. 274:21342–21348.
  • Bobkova, E. V., and B. D. Hall. 1997. Substrate specificity of the RNase activity of yeast RNA polymerase III. J. Biol. Chem. 272:22832–22839.
  • Calvo, O., R. Cuesta, J. Anderson, N. Gutierrez, M. T. Garcia-Barrio, A. G. Hinnebusch, and M. Tamame. 1999. GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:4167–4181.
  • Campbell, F. E., and D. R. Setzer. 1992. Transcription termination by RNA polymerase III: uncoupling of polymerase release from termination signal recognition. Mol. Cell. Biol. 12:2260–2272.
  • Chakshusmathi, G., S. D. Kim, D. A. Rubinson, and S. L. Wolin. 2003. A La protein requirement for efficient pre-tRNA folding. EMBO J. 22:6562–6572.
  • Chedin, S., M. Riva, P. Schultz, A. Sentenac, and C. Carles. 1998. The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination. Genes Dev. 12:3857–3871.
  • Elbashir, S. M., W. Lendeckel, and T. Tuschl. 2001. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15:188–200.
  • Fish, R. N., and C. M. Kane. 2002. Promoting elongation with transcript cleavage stimulatory factors. Biochim. Biophys. Acta 1577:287–307.
  • Forsburg, S. L. 1993. Comparison of Schizosaccharomyces pombe expression systems. Nucleic Acids Res. 21:2955–2956.
  • Hamada, M., Y. Huang, T. M. Lowe, and R. J. Maraia. 2001. Widespread use of TATA elements in the core promoters for RNA polymerases III, II, and I in fission yeast. Mol. Cell. Biol. 21:6870–6881.
  • Hamada, M., A. L. Sakulich, S. B. Koduru, and R. Maraia. 2000. Transcription termination by RNA polymerase III in fission yeast: a genetic and biochemically-tractable model system. J. Biol. Chem. 275:29076–29081.
  • Huang, Y., M. Hamada, and R. J. Maraia. 2000. Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICβ. J. Biol. Chem. 275:31480–31487.
  • Huang, Y., M. Hamada, and R. J. Maraia. 2003. RNA polymerase III from the fission yeast, Schizosaccharomyces pombe. Methods Enzymol. 370:165–173.
  • Huang, Y., E. McGillicuddy, M. Weindel, S. Dong, and R. Maraia. 2003. The fission yeast TFIIB-related factor limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment. Nucleic Acids Res. 31:2108–2116.
  • Intine, R. V., M. Dundr, T. Misteli, and R. J. Maraia. 2002. Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs. Mol. Cell 9:1113–1123.
  • Intine, R. V. A., A. L. Sakulich, S. B. Koduru, Y. Huang, E. Pierstorrf, J. L. Goodier, L. Phan, and R. J. Maraia. 2000. Transfer RNA maturation is controlled by phosphorylation of the human La antigen on serine 366. Mol. Cell 6:339–348.
  • Ishiguro, A., Y. Nogi, K. Hisatake, M. Muramatsu, and A. Ishihama. 2000. The Rpb6 subunit of fission yeast RNA polymerase II is a contact target of the transcription elongation factor TFIIS. Mol. Cell. Biol. 20:1263–1270.
  • Jeon, C., H. Yoon, and K. Agarwal. 1994. The transcription factor TFIIS zinc ribbon dipeptide Asp-Glu is critical for stimulation of elongation and RNA cleavage by RNA polymerase II. Proc. Natl. Acad. Sci. USA 91:9106–9110.
  • Johansson, M. J., and A. S. Bystrom. 2002. Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation. RNA 8:324–335.
  • Kadaba, S., A. Krueger, T. Trice, A. M. Krecic, A. G. Hinnebusch, and J. Anderson. 2004. Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae. Genes Dev. 18:1227–1240.
  • Kettenberger, H., K. J. Armache, and P. Cramer. 2003. Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage. Cell 114:347–357.
  • Komissarova, N., M. L. Kireeva, J. Becker, I. Sidorenkov, and M. Kashlev. 2003. Engineering of elongation complexes of bacterial and yeast RNA polymerases. Methods Enzymol. 370:233–251.
  • Kufel, J., and D. Tollervey. 2003. 3′-processing of yeast tRNATrp precedes 5′-processing. RNA 9:202–208.
  • Li, B., L. Howe, S. Anderson, J. R. Yates III, and J. L. Workman. 2003. The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. J. Biol. Chem. 278:8897–8903.
  • Maraia, R. J., and R. V. Intine. 2002. La protein and its associated small nuclear and nucleolar precursor RNAs. Gene Expr. 10:41–57.
  • Maundrell, K. 1993. Thiamine-repressible expression vectors pREP and pRIP for fission yeast. Gene 123:127–130.
  • Qian, X., C. Jeon, H. Yoon, K. Agarwal, and M. A. Weiss. 1993. Structure of a new nucleic-acid-binding motif in eukaryotic transcriptional elongation factor TFIIS. Nature 365:277–279.
  • Shaw, R. J., and D. Reines. 2000. Saccharomyces cerevisiae transcription elongation mutants are defective in PUR5 induction in response to nucleotide depletion. Mol. Cell. Biol. 20:7427–7437.
  • Shibuya, T., S. Tsuneyoshi, A. K. Azad, S. Urushiyama, Y. Ohshima, and T. Tani. 1999. Characterization of the ptr6+ gene in fission yeast: a possible involvement of a transcriptional coactivator TAF in nucleocytoplasmic transport of mRNA. Genetics 152:869–880.
  • Stefano, J. E. 1984. Purified lupus antigen La recognizes an oligouridylate stretch common to the 3′ termini of RNA polymerase III transcripts. Cell 36:145–154.
  • Van Horn, D. J., C. J. Yoo, D. Xue, H. Shi, and S. L. Wolin. 1997. The La protein in Schizosaccharomyces pombe: a conserved yet dispensable phosphoprotein that functions in tRNA maturation. RNA 3:1434–1443.
  • Whitehall, S. K., C. Bardeleben, and G. A. Kassavetis. 1994. Hydrolytic cleavage of nascent RNA in RNA polymerase III ternary transcription complexes. J. Biol. Chem. 269:2299–2306.
  • Willis, I., D. Frendewey, M. Nichols, A. Hottinger-Werlen, J. Schaack, and D. Soll. 1986. A single base change in the intron of a serine tRNA affects the rate of RNase P cleavage in vitro and suppressor activity in vivo in Saccharomyces cerevisiae. J. Biol. Chem. 261:5878–5885.
  • Wind, M., and D. Reines. 2000. Transcription elongation factor SII. Bioessays 22:327–336.
  • Wolin, S. L., and T. Cedervall. 2002. The La protein. Annu. Rev. Biochem. 71:375–403.
  • Yoo, C. J., and S. L. Wolin. 1997. The yeast La protein is required for the 3′ endonucleolytic cleavage that matures tRNA precursors. Cell 89:393–402.
  • Zaccolo, M., D. M. Williams, D. M. Brown, and E. Gherardi. 1996. An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. J. Mol. Biol. 255:589–603.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.