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Mammalian Genetic Models with Minimal or Complex Phenotypes

The Transcription Factor Gene Nfib Is Essential for both Lung Maturation and Brain Development

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Pages 685-698 | Received 25 Sep 2004, Accepted 10 Oct 2004, Published online: 27 Mar 2023

REFERENCES

  • Anselmo, M. A., S. Dalvin, P. Prodhan, K. Komatsuzaki, J. T. Aidlen, J. J. Schnitzer, J. Y. Wu, and T. B. Kinane. 2003. Slit and robo: expression patterns in lung development. Gene Expr. Patterns 3:13–19.
  • Bachurski, C. J., S. E. Kelly, S. W. Glasser, and T. A. Currier. 1997. Nuclear factor I family members regulate the transcription of surfactant protein-C. J. Biol. Chem. 272:32759–32766.
  • Bachurski, C. J., G. H. Yang, T. A. Currier, R. M. Gronostajski, and D. Hong. 2003. Nuclear factor I/thyroid transcription factor 1 interactions modulate surfactant protein C transcription. Mol. Cell. Biol. 23:9014–9024.
  • Ben-Arie, N., B. A. Hassan, N. A. Bermingham, D. M. Malicki, D. Armstrong, M. Matzuk, H. J. Bellen, and H. Y. Zoghbi. 2000. Functional conservation of atonal and Math1 in the CNS and PNS. Development 127:1039–1048.
  • Bouwman, P., H. Gollner, H. P. Elsasser, G. Eckhoff, A. Karis, F. Grosveld, S. Philipsen, and G. Suske. 2000. Transcription factor Sp3 is essential for post-natal survival and late tooth development. EMBO J. 19:655–661.
  • Chaudhry, A. Z., G. E. Lyons, and R. M. Gronostajski. 1997. Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development. Dev. Dyn. 208:313–325.
  • Chaudhry, A. Z., A. D. Vitullo, and R. M. Gronostajski. 1998. Nuclear factor I (NFI) isoforms differentially activate simple versus complex NFI-responsive promoters. J. Biol. Chem. 273:18538–18546.
  • Chaudhry, A. Z., A. D. Vitullo, and R. M. Gronostajski. 1999. Nuclear factor I-mediated repression of the mouse mammary tumor virus promoter is abrogated by the coactivators p300/CBP and SRC-1. J. Biol. Chem. 274:7072–7081.
  • Cole, T. J., N. M. Solomon, R. Van Driel, J. A. Monk, D. Bird, S. J. Richardson, R. J. Dilley, and S. B. Hooper. 2004. Altered epithelial cell proportions in the fetal lung of glucocorticoid receptor null mice. Am. J. Respir. Cell Mol. Biol. 30:613–619.
  • Costa, R. H., V. V. Kalinichenko, and L. Lim. 2001. Transcription factors in mouse lung development and function. Am. J. Physiol. Lung Cell. Mol. Physiol. 280:L823–L838.
  • das Neves, L., C. Duchala, F. Godinho, M. Haxhiu, C. Colmenares, W. Macklin, C. Campbell, K. Butz, and R. Gronostajski. 1999. Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus and agenesis of the corpus callosum. Proc. Natl. Acad. Sci. USA 96:11946–11951.
  • de Jong, R. N., and P. C. van der Vliet. 1999. Mechanism of DNA replication in eukaryotic cells: cellular host factors stimulating adenovirus DNA replication. Gene 236:1–12.
  • Engelkamp, D., P. Rashbass, A. Seawright, and V. van Heyningen. 1999. Role of Pax6 in development of the cerebellar system. Development 126:3585–3596.
  • Forster, E., A. Tielsch, B. Saum, K. H. Weiss, C. Johanssen, D. Graus-Porta, U. Muller, and M. Frotscher. 2002. Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus. Proc. Natl. Acad. Sci. USA 99:13178–13183.
  • Galceran, J., E. M. Miyashita-Lin, E. Devaney, J. L. Rubenstein, and R. Grosschedl. 2000. Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development 127:469–482.
  • Gesemann, M., E. D. Litwack, K. T. Yee, U. Christen, and D. D. O'Leary. 2001. Identification of candidate genes for controlling development of the basilar pons by differential display PCR. Mol. Cell. Neurosci. 18:1–12.
  • Geurts, J. M., E. F. Schoenmakers, E. Roijer, A. K. Astrom, G. Stenman, and W. J. van de Ven. 1998. Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas. Oncogene 16:865–872.
  • Glasser, S. W., M. S. Burhans, T. R. Korfhagen, C. L. Na, P. D. Sly, G. F. Ross, M. Ikegami, and J. A. Whitsett. 2001. Altered stability of pulmonary surfactant in SP-C-deficient mice. Proc. Natl. Acad. Sci. USA 98:6366–6371.
  • Greenberg, J. M., F. Y. Thompson, S. K. Brooks, J. M. Shannon, and A. L. Akeson. 2004. Slit and robo expression in the developing mouse lung. Dev. Dyn. 230:350–360.
  • Gronostajski, R. M. 1986. Analysis of nuclear factor I binding to DNA using degenerate oligonucleotides. Nucleic Acids Res. 14:9117–9132.
  • Gronostajski, R. M. 2000. Roles of the NFI/CTF gene family in transcription and development. Gene 249:31–45.
  • Grunder, A., T. T. Ebel, M. Mallo, G. Schwarzkopf, T. Shimizu, A. E. Sippel, and H. Schrewe. 2002. Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech. Dev. 112:69–77.
  • Hamatani, T., M. G. Carter, A. A. Sharov, and M. S. Ko. 2004. Dynamics of global gene expression changes during mouse preimplantation development. Dev. Cell 6:117–131.
  • Han, R. N., S. Babaei, M. Robb, T. Lee, R. Ridsdale, C. Ackerley, M. Post, and D. J. Stewart. 2004. Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia. Circ. Res. 94:1115–1123.
  • Hogan, B. L., and J. M. Yingling. 1998. Epithelial/mesenchymal interactions and branching morphogenesis of the lung. Curr. Opin. Genet. Dev. 8:481–486.
  • Hummel, T., K. Schimmelpfeng, and C. Klambt. 1999. Commissure formation in the embryonic CNS of Drosophila. Development 126:771–779.
  • Jen, J. C., W. M. Chan, T. M. Bosley, J. Wan, J. R. Carr, U. Rub, D. Shattuck, G. Salamon, L. C. Kudo, J. Ou, D. D. Lin, M. A. Salih, T. Kansu, H. Al Dhalaan, Z. Al Zayed, D. B. MacDonald, B. Stigsby, A. Plaitakis, E. K. Dretakis, I. Gottlob, C. Pieh, E. I. Traboulsi, Q. Wang, L. Wang, C. Andrews, K. Yamada, J. L. Demer, S. Karim, J. R. Alger, D. H. Geschwind, T. Deller, N. L. Sicotte, S. F. Nelson, R. W. Baloh, and E. C. Engle. 2004. Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis. Science 304:1509–1513.
  • Kaplan, F., J. Comber, R. Sladek, T. J. Hudson, L. J. Muglia, T. Macrae, S. Gagnon, M. Asada, J. A. Brewer, and N. B. Sweezey. 2003. The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. Am. J. Respir. Cell Mol. Biol. 28:33–41.
  • Kralovics, R., Y. Guan, and J. T. Prchal. 2002. Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp. Hematol. 30:229–236.
  • Kruse, U., F. Qian, and A. E. Sippel. 1991. Identification of a fourth nuclear factor I gene in chicken by cDNA cloning: NFI-X. Nucleic Acids Res. 19:6641.
  • Kruse, U., and A. E. Sippel. 1994. Transcription factor nuclear factor I proteins form stable homo- and heterodimers. FEBS Lett. 348:46–50.
  • Labarca, C., and K. Paigen. 1980. A simple, rapid, and sensitive DNA assay procedure. Anal. Biochem. 102:344–352.
  • Li, S., F. Qiu, A. Xu, S. M. Price, and M. Xiang. 2004. Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene. J. Neurosci. 24:3104–3114.
  • Liu, M., S. J. Pleasure, A. E. Collins, J. L. Noebels, F. J. Naya, M. J. Tsai, and D. H. Lowenstein. 2000. Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc. Natl. Acad. Sci. USA 97:865–870.
  • Livy, D. J., and D. Wahlsten. 1997. Retarded formation of the hippocampal commissure in embryos from mouse strains lacking a corpus callosum. Hippocampus 7:2–14.
  • Livy, D. J., and D. Wahlsten. 1991. Tests of genetic allelism between four inbred mouse strains with absent corpus callosum. J. Hered. 82:459–464.
  • Long, H., C. Sabatier, L. Ma, A. Plump, W. Yuan, D. M. Ornitz, A. Tamada, F. Murakami, C. S. Goodman, and M. Tessier-Lavigne. 2004. Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron 42:213–223.
  • Lu, M., E. A. Grove, and R. J. Miller. 2002. Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc. Natl. Acad. Sci. USA 99:7090–7095.
  • Marillat, V., C. Sabatier, V. Failli, E. Matsunaga, C. Sotelo, M. Tessier-Lavigne, and A. Chedotal. 2004. The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons. Neuron 43:69–79.
  • Meisterernst, M., I. Gander, L. Rogge, and E. L. Winnacker. 1988. A quantitative analysis of nuclear factor I/DNA interactions. Nucleic Acids Res. 16:4419–4435.
  • Mucenski, M. L., S. E. Wert, J. M. Nation, D. E. Loudy, J. Huelsken, W. Birchmeier, E. E. Morrisey, and J. A. Whitsett. 2003. β-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis. J. Biol. Chem. 278:40231–40238.
  • Murtagh, J., F. Martin, and R. M. Gronostajski. 2003. The nuclear factor I (NFI) gene family in mammary gland development and function. J. Mammary Gland Biol. Neoplasia. 8:241–254.
  • Nagata, K., R. Guggenheimer, T. Enomoto, J. Lichy, and J. Hurwitz. 1982. Adenovirus DNA replication in vitro. Identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex. Proc. Natl. Acad. Sci. USA 79:6438–6442.
  • Nagata, K., R. A. Guggenheimer, and J. Hurwitz. 1983. Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA. Proc. Natl. Acad. Sci. USA 80:6177–6181.
  • National Institutes of Health. 1994. Report of the Consensus Development Conference on the Effect of Corticosteroids for Fetal Maturation on Perinatal Outcomes. National Institutes of Health, Bethesda Md. http://www.nichd.nih.gov/publications/pubs/corticosteroids/Corticosteroids.html.
  • Pellegrini, M., A. Mansouri, A. Simeone, E. Boncinelli, and P. Gruss. 1996. Dentate gyrus formation requires Emx2. Development 122:3893–3898.
  • Prodhan, P., and T. B. Kinane. 2002. Developmental paradigms in terminal lung development. Bioessays 24:1052–1059.
  • Reynolds, P. R., M. L. Mucenski, T. D. Le Cras, W. C. Nichols, and J. A. Whitsett. 2004. Midkine is regulated by hypoxia and causes pulmonary vascular remodeling. J. Biol. Chem. 279:37124–37132.
  • Richards, L. J. 2002. Surrounded by Slit-how forebrain commissural axons can be led astray. Neuron 33:153–155.
  • Rupp, R., U. Kruse, G. Multhaup, U. Gobel, K. Beyreuther, and A. Sippel. 1990. Chicken NFI/TGGCA proteins are encoded by at least three independent genes: NFI-A, NFI-B and NFI-C with homologues in mammalian genomes. Nucleic Acids Res. 18:2607–2616.
  • Savaskan, N. E., G. Alvarez-Bolado, R. Glumm, R. Nitsch, T. Skutella, and B. Heimrich. 2002. Impaired postnatal development of hippocampal neurons and axon projections in the Emx2−/− mutants. J. Neurochem. 83:1196–1207.
  • Schuur, E. R., U. Kruse, J. S. Iacovoni, and P. K. Vogt. 1995. Nuclear factor I interferes with transformation induced by nuclear oncogenes. Cell Growth Differ. 6:219–227.
  • Sekine, K., H. Ohuchi, M. Fujiwara, M. Yamasaki, T. Yoshizawa, T. Sato, N. Yagishita, D. Matsui, Y. Koga, N. Itoh, and S. Kato. 1999. Fgf10 is essential for limb and lung formation. Nat. Genet. 21:138–141.
  • Shannon, J. M., and B. A. Hyatt. 2004. Epithelial-mesenchymal interactions in the developing lung. Annu. Rev. Physiol. 66:625–645.
  • Shi, W., N. Heisterkamp, J. Groffen, J. Zhao, D. Warburton, and V. Kaartinen. 1999. TGF-β3-null mutation does not abrogate fetal lung maturation in vivo by glucocorticoids. Am. J. Physiol. 277:L1205–L1213.
  • Shu, T., K. G. Butz, C. Plachez, R. M. Gronostajski, and L. J. Richards. 2003. Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice. J. Neurosci. 23:203–212.
  • Shu, T., A. C. Puche, and L. J. Richards. 2003. Development of midline glial populations at the corticoseptal boundary. J. Neurobiol. 57:81–94.
  • Shu, T., and L. J. Richards. 2001. Cortical axon guidance by the glial wedge during the development of the corpus callosum. J. Neurosci. 21:2749–2758.
  • Shu, T., V. Sundaresan, M. M. McCarthy, and L. J. Richards. 2003. Slit2 guides both precrossing and postcrossing callosal axons at the midline in vivo. J. Neurosci. 23:8176–8184.
  • Soriano, P., C. Montgomery, R. Geske, and A. Bradley. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64:693–702.
  • Steele-Perkins, G., K. G. Butz, G. E. Lyons, M. Zeichner-David, H.-J. Kim, M. I. Cho, and R. M. Gronostajski. 2003. Essential role for NFI-C/CTF transcription-replication factor in tooth root development. Mol. Cell. Biol. 23:1075–1084.
  • Stiles, A. D., D. Chrysis, H. W. Jarvis, B. Brighton, and B. M. Moats-Staats. 2001. Programmed cell death in normal fetal rat lung development. Exp. Lung Res. 27:569–587.
  • Sundaresan, V., E. Mambetisaeva, W. Andrews, A. Annan, B. Knoll, G. Tear, and L. Bannister. 2004. Dynamic expression patterns of Robo (Robo1 and Robo2) in the developing murine central nervous system. J. Comp. Neurol. 468:467–481.
  • Tybulewicz, V. L., C. E. Crawford, P. K. Jackson, R. T. Bronson, and R. C. Mulligan. 1991. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65:1153–1163.
  • Warburton, D., M. Schwarz, D. Tefft, G. Flores-Delgado, K. D. Anderson, and W. V. Cardoso. 2000. The molecular basis of lung morphogenesis. Mech. Dev. 92:55–81.
  • Xian, J., K. J. Clark, R. Fordham, R. Pannell, T. H. Rabbitts, and P. H. Rabbitts. 2001. Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene. Proc. Natl. Acad. Sci. USA 98:15062–15066.
  • Yagi, T., Y. Ikawa, K. Yoshida, Y. Shigetani, N. Takeda, I. Mabuchi, T. Yamamoto, and S. Aizawa. 1990. Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection. Proc. Natl. Acad. Sci. USA 87:9918–9922.
  • Yu, H., A. Wessels, J. Chen, A. L. Phelps, J. Oatis, G. S. Tint, and S. B. Patel. 2 February 2004, posting date. Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. BMC Dev. Biol. 4:1. [Online.] http://www.biomedcentral.com/1471-213X/4/1.
  • Zhang, P., C. Wong, D. Liu, M. Finegold, J. W. Harper, and S. J. Elledge. 1999. p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step. Genes Dev. 13:213–224.
  • Zhao, Y., H. Z. Sheng, R. Amini, A. Grinberg, E. Lee, S. Huang, M. Taira, and H. Westphal. 1999. Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Science 284:1155–1158.
  • Zhou, C. J., C. Zhao, and S. J. Pleasure. 2004. Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities. J. Neurosci. 24:121–126.

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