Interaction between GATA and the C/EBP Family of Transcription Factors Is Critical in GATA-Mediated Suppression of Adipocyte Differentiation

REFERENCES

• Blobel, G. A., T. Nakajima, R. Eckner, M. Montminy, and S. H. Orkin. 1998. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation. Proc. Natl. Acad. Sci. USA 95:2061–2066.
   PubMedGoogle Scholar
• Boyes, J., P. Byfield, Y. Nakatani, and V. Ogryzko. 1998. Regulation of activity of the transcription factor GATA-1 by acetylation. Nature 396:594–598.
   PubMed Web of Science ®Google Scholar
• Cao, Z., R. M. Umek, and S. L. McKnight. 1991. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1538–1552.
   PubMed Web of Science ®Google Scholar
• Chen, P. L., D. J. Riley, Y. Chen, and W. H. Lee. 1996. Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev. 10:2794–2804.
   PubMedGoogle Scholar
• Crawford, S. E., C. Qi, P. Misra, V. Stellmach, M. S. Rao, J. D. Engel, Y. Zhu, and J. K. Reddy. 2002. Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors. J. Biol. Chem. 277:3585–3592.
   PubMed Web of Science ®Google Scholar
• Freytag, S. O., D. L. Paielli, and J. D. Gilbert. 1994. Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev. 8:1654–1663.
   PubMed Web of Science ®Google Scholar
• Ge, K., M. Guermah, C. X. Yuan, M. Ito, A. E. Wallberg, B. M. Spiegelman, and R. G. Roeder. 2002. Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis. Nature 417:563–567.
   PubMed Web of Science ®Google Scholar
• Juan, T. S., D. R. Wilson, M. D. Wilde, and G. J. Darlington. 1993. Participation of the transcription factor C/EBPδ in the acute-phase regulation of the human gene for complement component C3. Proc. Natl. Acad. Sci. USA 90:2584–2588.
   PubMedGoogle Scholar
• Landschulz, W. H., P. F. Johnson, and S. L. McKnight. 1989. The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite. Science 243:1681–1688.
   PubMedGoogle Scholar
• Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90:8392–8396.
   PubMed Web of Science ®Google Scholar
• Rekhtman, N., F. Radparvar, T. Evans, and A. I. Skoultchi. 1999. Direct interaction of hematopoietic transcription factors PU. 1 and GATA-1: functional antagonism in erythroid cells. Genes Dev. 13:1398–1411.
   PubMed Web of Science ®Google Scholar
• Rosen, E. D., C. J. Walkey, P. Puigserver, and B. M. Spiegelman. 2000. Transcriptional regulation of adipogenesis. Genes Dev. 14:1293–1307.
   PubMed Web of Science ®Google Scholar
• Tanaka, T., N. Yoshida, T. Kishimoto, and S. Akira. 1997. Defective adipocyte differentiation in mice lacking the C/EBPβ and/or C/EBPδ gene. EMBO J. 16:7432–7443.
   PubMed Web of Science ®Google Scholar
• Tong, Q., G. Dalgin, H. Xu, C. N. Ting, J. M. Leiden, and G. S. Hotamisligil. 2000. Function of GATA transcription factors in preadipocyte-adipocyte transition. Science 290:134–138.
   PubMed Web of Science ®Google Scholar
• Tong, Q., and G. S. Hotamisligil. 2001. Molecular mechanisms of adipocyte differentiation. Rev. Endocr. Metab. Disord. 2:349–355.
   PubMedGoogle Scholar
• Tontonoz, P., E. Hu, R. A. Graves, A. I. Budavari, and B. M. Spiegelman. 1994. mPPARγ2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8:1224–1234.
   PubMed Web of Science ®Google Scholar
• Tontonoz, P., E. Hu, and B. M. Spiegelman. 1994. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 79:1147–1156.
   PubMed Web of Science ®Google Scholar
• Tsang, A. P., J. E. Visvader, C. A. Turner, Y. Fujiwara, C. Yu, M. J. Weiss, M. Crossley, and S. H. Orkin. 1997. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90:109–119.
   PubMed Web of Science ®Google Scholar
• Visvader, J. E., M. Crossley, J. Hill, S. H. Orkin, and J. M. Adams. 1995. The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line. Mol. Cell Biol. 15:634–641.
   PubMed Web of Science ®Google Scholar
• Wang, N. D., M. J. Finegold, A. Bradley, C. N. Ou, S. V. Abdelsayed, M. D. Wilde, L. R. Taylor, D. R. Wilson, and G. J. Darlington. 1995. Impaired energy homeostasis in C/EBPα knockout mice. Science 269:1108–1112.
   PubMed Web of Science ®Google Scholar
• Whyatt, D. J., A. Karis, I. C. Harkes, A. Verkerk, N. Gillemans, A. G. Elefanty, G. Vairo, R. Ploemacher, F. Grosveld, and S. Philipsen. 1997. The level of the tissue-specific factor GATA-1 affects the cell-cycle machinery. Genes Funct. 1:11–24.
   PubMedGoogle Scholar
• Wu, Z., E. D. Rosen, R. Brun, S. Hauser, G. Adelmant, A. E. Troy, C. McKeon, G. J. Darlington, and B. M. Spiegelman. 1999. Cross-regulation of C/EBPα and PPARγ controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol. Cell 3:151–158.
   PubMed Web of Science ®Google Scholar
• Wu, Z., Y. Xie, N. L. Bucher, and S. R. Farmer. 1995. Conditional ectopic expression of C/EBPβ in NIH-3T3 cells induces PPARγ and stimulates adipogenesis. Genes Dev. 9:2350–2363.
   PubMed Web of Science ®Google Scholar
• Yamauchi, T., Y. Oike, J. Kamon, H. Waki, K. Komeda, A. Tsuchida, Y. Date, M. X. Li, H. Miki, Y. Akanuma, R. Nagai, S. Kimura, T. Saheki, M. Nakazato, T. Naitoh, K. Yamamura, and T. Kadowaki. 2002. Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice. Nat. Genet. 30:221–226.
   PubMed Web of Science ®Google Scholar
• Yeh, W. C., Z. Cao, M. Classon, and S. L. McKnight. 1995. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev. 9:168–181.
   PubMed Web of Science ®Google Scholar
• Zhang, P., G. Behre, J. Pan, A. Iwama, N. Wara-Aswapati, H. S. Radomska, P. E. Auron, D. G. Tenen, and Z. Sun. 1999. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU. 1. Proc. Natl. Acad. Sci. USA 96:8705–8710.
   PubMed Web of Science ®Google Scholar