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Signal Transduction

Coordinate Regulation of the Mother Centriole Component Nlp by Nek2 and Plk1 Protein Kinases

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Pages 1309-1324 | Received 16 Jul 2004, Accepted 12 Nov 2004, Published online: 27 Mar 2023

REFERENCES

  • Bornens, M. 2002. Centrosome composition and microtubule anchoring mechanisms. Curr. Opin. Cell Biol. 14:25–34.
  • Bouckson-Castaing, V., M. Moudjou, D. J. Ferguson, S. Mucklow, Y. Belkaid, G. Milon, and P. J. Crocker. 1996. Molecular characterization of ninein, a new coiled-coil protein of the centrosome. J. Cell Sci. 109:179–190.
  • Casenghi, M., P. Meraldi, U. Weinhart, P. I. Duncan, R. Korner, and E. A. Nigg. 2003. Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev. Cell 5:113–125.
  • Cheng, K.-Y., E. D. Lowe, J. Sinclair, E. A. Nigg, and L. N. Johnson. 2003. The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. EMBO J. 22:5757–5768.
  • Compton, D. A. 2000. Spindle assembly in animal cells. Annu. Rev. Biochem. 69:95–114.
  • Dictenberg, J. B., W. Zimmerman, C. A. Sparks, A. Young, C. Vidair, Y. Zheng, W. Carrington, F. S. Fay, and S. J. Doxsey. 1998. Pericentrin and g-tubulin form a protein complex and are organized into a novel lattice at the centrosome. J. Cell Biol. 141:163–174.
  • do Carmo Avides, M., and D. M. Glover. 1999. Abnormal spindle protein, Asp, and the integrity of mitotic centrosomal microtubule organizing centers. Science 283:1733–1735.
  • Doxsey, S. 2001. Re-evaluating centrosome function. Nat. Revs: Mol. Cell. Biol. 2:688–698.
  • Durfee, T., K. Becherer, P.-L. Chen, S.-H. Yeh, Y. Yang, A. E. Kilburn, W.-H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7:555–569.
  • Elia, A. E., P. Rellos, L. F. Haire, J. W. Chao, F. J. Ivins, K. Hoepker, D. Mohammad, L. C. Cantley, S. J. Smerdon, and M. B. Yaffe. 2003b. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell 115:83–95.
  • Elia, A. E. H., L. C. Cantley, and M. B. Yaffe. 2003a. Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science 299:1228–1231.
  • Faragher, A. J., and A. M. Fry. 2003. Nek2 kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles. Mol. Biol. Cell 14:2876–2889.
  • Fry, A. M. 2002. The Nek2 protein kinase: a novel regulator of centrosome structure. Oncogene 21:6184–6194.
  • Fry, A. M., L. Arnaud, and E. A. Nigg. 1999. Activity of the human centrosomal kinase, Nek2, depends upon an unusual leucine zipper dimerization motif. J. Biol. Chem. 274:16304–16310.
  • Fry, A. M., P. Descombes, C. Twomey, R. Bacchieri, and E. A. Nigg. 2000. The NIMA-related kinase X-Nek2B is required for efficient assembly of the zygotic centrosome in Xenopus laevis.. J. Cell Sci. 113:1973–1984.
  • Fry, A. M., T. Mayor, P. Meraldi, Y.-D. Stierhof, K. Tanaka, and E. A. Nigg. 1998b. C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. J. Cell Biol. 141:1563–1574.
  • Fry, A. M., P. Meraldi, and E. A. Nigg. 1998a. A centrosomal function for the human Nek2 protein kinase, a member of the NIMA-family of cell cycle regulators. EMBO J. 17:470–481.
  • Fry, A. M., and E. A. Nigg. 1997. Characterization of mammalian NIMA-related kinases. Methods Enzymol. 283:270–282.
  • Golsteyn, R. M., K. E. Mundt, A. M. Fry, and E. A. Nigg. 1995. Cell cycle regulation of the activity and subcellular localization of PLK1, a human protein kinase implicated in mitotic spindle function. J. Cell Biol. 129:1617–1628.
  • Grallert, A., and I. M. Hagan. 2002. S. pombe NIMA related kinase, Fin1, regulates spindle formation, and an affinity of Polo for the SPB. EMBO J. 21:3096–3107.
  • Hames, R. S., and A. M. Fry. 2002. Alternative splice variants of the human centrosomal kinase Nek2 exhibit distinct patterns of expression in mitosis. Biochem. J. 361:77–85.
  • Hames, R. S., S. L. Wattam, H. Yamano, R. Bacchieri, and A. M. Fry. 2001. APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box. EMBO J. 20:7117–7127.
  • Hartman, J. J., J. Mahr, K. McNally, K. Okawa, A. Iwamatsu, S. Thomas, S. Cheesman, J. Heuser, R. D. Vale, and F. J. McNally. 1998. Katanin, a microtubule-severing protein is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit. Cell 93:277–287.
  • Heald, R., R. Tournebize, A. Habermann, E. Karsenti, and A. Hyman. 1997. Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization. J. Cell Biol. 138:615–628.
  • James, P., J. Halladay, and E. A. Craig. 1996. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144:1425–1436.
  • Jang, Y., C. Lin, S. Ma, and R. L. Erikson. 2002. Functional studies on the role of the C-terminal domain of mammalian polo-like kinase. Proc. Natl. Acad. Sci. USA 99:1984–1989.
  • Job, D., O. Valiron, and B. Oakley. 2003. Microtubule nucleation. Curr. Opin. Cell Biol. 15:111–117.
  • Kawaguchi, S., and Y. Zheng. 2004. Characterization of a Drosophila centrosome protein CP309 that shares homology with kendrin and CG-NAP. Mol. Biol. Cell 15:37–45.
  • Keating, T. J., and G. G. Borisy. 1999. Centrosomal and non-centrosomal microtubules. Biol. Cell 91:321–329.
  • Keating, T. J., and G. G. Borisy. 2000. Immunostructural evidence for the template mechanism of microtubule nucleation. Nat. Cell Biol. 2:352–357.
  • Kelm, O., M. Wind, W. D. Lehmann, and E. A. Nigg. 2002. Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1. J. Biol. Chem. 277:25247–25256.
  • Keryer, G., B. Di Fiore, C. Celati, K. F. Lechtreck, M. Mogensen, A. Delouvee, P. Lavia, M. Bornens, and A.-M. Tassin. 2003. Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity. Mol. Biol. Cell 14:4260–4271.
  • Lupas, A. 1996. Prediction and analysis of coiled-coil structures. Methods Enzymol. 266:513–525.
  • Mayor, T., U. Hacker, Y.-D. Stierhof, and E. A. Nigg. 2002. The mechanism regulating dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles. J. Cell Sci. 115:3275–3284.
  • Mayor, T., K. Tanaka, Y.-D. Stierhof, A. M. Fry, and E. A. Nigg. 2000. The centrosomal protein C-Nap1 displays properties supporting a role in cell cycle-regulated centrosome cohesion. J. Cell Biol. 151:837–846.
  • McIntosh, J. R., E. L. Grishchuk, and R. R. West. 2002. Chromosome-microtubule interactions during mitosis. Annu. Rev. Cell Dev. Biol. 18:193–219.
  • Meraldi, P., R. Honda, and E. A. Nigg. 2002. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53−/− cells. EMBO J. 21:483–492.
  • Meraldi, P., and E. A. Nigg. 2001. Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. J. Cell Sci. 114:3749–3757.
  • Mogensen, M. M., A. Malik, M. Piel, V. Bouckson-Castaing, and M. Bornens. 2000. Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: the role of ninein. J. Cell Sci. 113:3013–3023.
  • Moritz, M., M. B. Braunfeld, V. Guenebaut, J. Heuser, and D. A. Agard. 2000. Structure of the g-tubulin ring complex: a template for microtubule nucleation. Nat. Cell Biol. 2:365–370.
  • Neef, R., C. Preisinger, J. Sutcliffe, R. Kopajtich, E. A. Nigg, T. U. Mayer, and F. A. Barr. 2003. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J. Cell Biol. 162:863–875.
  • Nigg, E. A. 2002. Centrosome aberrations: cause or consequence of cancer progression. Nat. Rev. Cancer 2:815–825.
  • Nigg, E. A. 2001. Mitotic kinases as regulators of cell division and its checkpoints. Nat. Rev. Mol. Cell. Biol. 2:21–32.
  • Piel, M., P. Meyer, A. Khodjakov, C. L. Rieder, and M. Bornens. 2000. The respective contributions of the mother and daughter centrioles to centrosome activity and behaviour in vertebrate cells. J. Cell Biol. 149:317–329.
  • Quintyne, N. J., S. R. Gill, D. M. Eckley, C. L. Crego, D. A. Compton, and T. A. Schroer. 1999. Dynactin is required for microtubule anchoring at fibroblast centrosomes. J. Cell Biol. 147:321–334.
  • Reynolds, N., and H. Ohkura. 2003. Polo boxes form a single functional domain that mediates interactions with multiple proteins in fission yeast polo kinase. J. Cell Sci. 116:1377–1387.
  • Schroer, T. A. 2001. Microtubules don and doff their caps: dynamic attachments at plus and minus ends. Curr. Opin. Cell Biol. 13:92–96.
  • Seong, Y.-S., K. Kamijo, J.-S. Lee, E. Fernandez, R. Kuriyama, T. Miki, and K. S. Lee. 2002. A spindle checkpoint arrest and a cytokinesis failure by the dominant-negative polo-box domain of Plk1 in U-2 OS cells. J. Biol. Chem. 277:32282–32293.
  • Song, S., T. Z. Grenfell, S. Garfield, R. L. Erikson, and K. S. Lee. 2000. Essential function of the polo box of Cdc5 in subcellular localization and induction of cytokinetic structures. Mol. Cell. Biol. 20:286–298.
  • Takahashi, M., A. Yamagiwa, T. Nishimura, H. Mukai, and Y. Ono. 2002. Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. Mol. Biol. Cell 13:3235–3245.
  • Twomey, C., S. L. Wattam, M. R. Pillai, J. Rapley, J. E. Baxter, and A. M. Fry. 2004. Nek2B stimulates zygotic centrosome assembly in Xenopus laevis in a kinase-independent manner. Dev. Biol. 265:384–398.
  • Uto, K., N. Nakajo, and N. Sagata. 1999. Two structural variants of Nek2 kinase, termed Nek2A and Nek2B, are differentially expressed in Xenopus tissues and development. Dev. Biol. 208:456–464.
  • Wiese, C., and Y. Zhang. 2000. A new function for the gamma-tubulin ring complex as a microtubule minus-end cap. Nat. Cell Biol. 2:358–364.

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