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Article

Oxidative Stress-Responsive Transcription Factor ATF3 Potentially Mediates Diabetic Angiopathy

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Pages 1087-1097 | Received 31 May 2005, Accepted 08 Nov 2005, Published online: 27 Mar 2023

REFERENCES

  • Ala-aho, R., M. Ahonen, S. J. George, J. Heikkila, R. Grenman, M. Kallajoki, and V. M. Kahari. 2004. Targeted inhibition of human collagenase-3 (MMP-13) expression inhibits squamous cell carcinoma growth in vivo. Oncogene 23:5111–5123.
  • Allan, A. L., C. Albanese, R. G. Pestell, and J. LaMarre. 2001. Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes. J. Biol. Chem. 276:27272–27280.
  • Benezra, R., S. Rafil, and D. Lyden. 2001. The Id proteins and angiogenesis. Oncogene 20:8334–8341.
  • Brownlee, M. 2001. Biochemistry and molecular cell biology of diabetic complications. Nature 414:813–820.
  • Chen, B. P. C., G. Liang, J. Whelan, and T. Hai. 1994. ATF3 and ATF3ΔZip. Transcriptional repression versus activation by alternatively spliced isoforms. J. Biol. Chem. 269:15819–15826.
  • Chen, B. P. C., C. D. Wolfgang, and T. Hai. 1996. Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10. Mol. Cell. Biol. 16:1157–1168.
  • Dong, J., S. Fujii, H. Li, H. Nakabayashi, M. Sakai, S. Nishi, D. Goto, T. Furumoto, S. Imagawa, T. A. K. M. Zaman, and A. Kitabatake. 2005. Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-δ. Arterioscler. Thromb. Vasc. Biol. 25:1078–1084.
  • Era, T., and O. N. Witte. 2000. Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate. Proc. Natl. Acad. Sci. USA 97:1737–1742.
  • Fan, F., S. Jin, S. A. Amundson, T. Tong, W. Fan, H. Zhao, X. Zhu, L. Mazzacurati, X. Li, K. L. Petrik, A. J. Fornace, Jr., B. Rajasekaran, and Q. Zhan. 2002. ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth. Oncogene 21:7488–7496.
  • Goruppi, S., J. V. Bonventre, and J. M. Kyriakis. 2002. Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy. EMBO J. 21:5427–5436.
  • Hai, T., C. D. Wolfgang, D. K. Marsee, A. E. Allen, and U. Sivaprasad. 1999. ATF3 and stress responses. Gene Expr. 7:321–335.
  • Hashimoto, Y., C. Zhang, J. Kawauchi, I. Imoto, M. T. Adachi, J. Inazawa, T. Amagasa, T. Hai, and S. Kitajima. 2002. An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli. Nucleic Acids Res. 30:2398–2406.
  • Inoue, K., T. Zama, T. Kamimoto, R. Aoki, Y. Ikeda, H. Kimura, and M. Hagiwara. 2004. TNF-α induced ATF3 expression is bidirectionally regulated by the JNK and ERK pathways in vascular endothelial cells. Genes Cells 9:59–70.
  • Kang, Y., C. R. Chen, and J. Massagué. 2003. A self-enabling TGFβ response coupled to stress signaling: Smad engages factor ATF3 for Id1 repression in epithelial cells. Mol. Cell 11:915–926.
  • Karnovsky, M. J., and G. B. Ryan. 1975. Structure of the glomerular slit diaphragm in freeze-fractured normal rat kidney. J. Cell Biol. 65:233–236.
  • Kawauchi, J., C. Zhang, K. Nobori, Y. Hashimoto, M. T. Adachi, A. Noda, M. Sunamori, and S. Kitajima. 2002. Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-α-induced apoptosis through down-regulation of p53 transcription. J. Biol. Chem. 277:39025–39034.
  • Khatri, J. J., C. Johnson, R. Magid, S. M. Lessner, K. M. Laude, S. I. Dikalov, D. G. Harrison, H. J. Sung, Y. Rong, and Z. S. Galis. 2004. Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma. Circulation 109:520–525.
  • Kobayashi, S., E. Ito, R. Honma, Y. Nojima, M. Shibuya, S. Watanabe, and Y. Maru. 2004. Dynamic regulation of gene expression by the Flt-1 kinase and Matrigel in endothelial tubulogenesis. Genomics 84:185–192.
  • Kobayashi, S., Y. Nojima, M. Shibuya, and Y. Maru. 2004. Nox1 regulates apoptosis and potentially stimulates branching morphogenesis in sinusoidal endothelial cells. Exp. Cell Res. 300:455–462.
  • Li, N., and M. Karin. 1999. Is NF-κB the sensor of oxidative stress? FASEB J. 13:1137–1143.
  • Maru, Y., S. Yamaguchi, T. Takahashi, H. Ueno, and M. Shibuya. 1998. Virally activated Ras cooperates with integrin to induce tubulogenesis in sinusoidal endothelial cell lines. J. Cell. Physiol. 176:223–234.
  • Maru, Y., S. Yamaguchi, and M. Shibuya. 1998. Flt-1, a receptor for vascular endothelial growth factor, has transforming and morphogenic potentials. Oncogene 16:2585–2595.
  • Maru, Y., H. Hirosawa, and M. Shibuya. 2000. An oncogenic form of the Flt-1 kinase has a tubulogenic potential in a sinusoidal endothelial cell line. Eur. J. Cell Biol. 79:130–143.
  • Mo, F. E., A. G. Muntean, C. C. Chen, D. B. Stolz, S. C. Watkins, and L. F. Lau. 2002. CYR61 (CCN1) is essential for placental development and vascular integrity. Mol. Cell. Biol. 22:8709–8720.
  • Moeller, B. J., Y. Cao, C. Y. Li, and M. W. Dewhirst. 2004. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell 5:429–441.
  • Mori, S., K. Kawano, T. Hirashima, and T. Natori. 1996. Relationships between diet control and the development of spontaneous type II diabetes and diabetic nephropathy in OLETF rats. Diabetes Res. Clin. Pract. 33:145–152.
  • Nawa, T., M. T. Nawa, M. T. Adachi, I. Uchimura, R. Shimokawa, K. Fujisawa, A. Tanaka, F. Numano, and S. Kitajima. 2002. Expression of transcriptional repressor ATF3/LRF1 in human atherosclerosis colocalization and possible involvement in cell death of vascular endothelial cells. Atherosclerosis 16:281–291.
  • Neeper, M., A. M. Schmidt, J. Brett, S. D. Yan, F. Wang, Y. C. Pan, K. Elliston, D. Stern, and A. Shaw. 1992. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J. Biol. Chem. 267:14998–15004.
  • Nilssen, L. S., J. Ødegård, G. H. Thoresen, A. Molven, D. Sandnes, and T. Christoffersen. 2004. G protein-coupled receptor agonist-stimulated expression of ATF3/LRF-1 and c-myc and comitogenic effects in hepatocytes do not require EGF receptor transactivation. J. Cell. Physiol. 201:349–358.
  • O'Brien, L. E., M. M. Zegers, and K. E. Mostov. 2002. Building epithelial architecture: insights from three-dimensional culture models. Nat. Rev. Mol. Cell Biol. 3:531–537.
  • Pan, Y., H. Chen, F. Siu, and M. S. Kilberg. 2003. Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter. J. Biol. Chem. 278:38402–38412.
  • Pearson, A. G., C. W. Gray, J. F. Pearson, J. M. Greenwood, M. J. During, and M. Dragunow. 2003. ATF3 enhances c-Jun mediated neurite sprouting. Mol. Brain Res. 120:38–45.
  • Perez, S., E. Vial, V. H. Dam, and M. Castellazzi. 2001. Transcription factor ATF3 partially transforms chick embryo fibroblasts by promoting growth factor-independent proliferation. Oncogene 20:1135–1141.
  • Ploplis, V. A., R. Balsara, M. J. Sandoval-Cooper, Z. J. Yin, J. Betten, N. Modi, D. Gadoua, D. Donahue, J. A. Martin, and F. J. Castellino. 2003. Enhanced in vitro proliferation of aortic endothelial cells from plasminogen activator inhibitor-1-deficient mice. J. Biol. Chem. 279:6143–6151.
  • Qian, Y., J. Luo, S. S. Leonard, G. K. Harris, L. Millecchia, D. C. Flynn, and X. Shi. 2003. Hydrogen peroxide formation and actin filament reorganization by Cdc42 are essential for ethanol-induced in vitro angiogenesis. J. Biol. Chem. 278:16189–16197.
  • Saito, F., M. Kawaguchi, J. Izumida, T. Asakura, K. Maehara, and Y. Maruyama. 2003. Alteration in haemodynamics and pathological changes in the cardiovascular system during the development of type 2 diabetes mellitus in OLETF rats. Diabetologia 46:1161–1169.
  • Sawdey, M. S., and D. J. Loskutoff. 1991. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta. J. Clin. Investig. 88:1346–1353.
  • Senger, A. P., K. P. Claffey, J. E. Benes, C. A. Perruzzi, A. P. Sergiou, and M. Detmar. 1997. Angiogenesis promoted by vascular endothelial growth factor: regulation through α1β1 and α2β1 integrins. Proc. Natl. Acad. Sci. USA 94:13612–13617.
  • Stennett, L. S., A. I. Riker, T. M. Kroll, J. Chamberlin, T. Miki, B. J. Nickoloff, and I. C. Le Poole. 2004. Expression of gp100 and CDK2 in melanoma cells is not coregulated by a shared promoter region. Pigment Cell Res. 17:525–532.
  • Stone, J. R., and J. Collins. 2002. The role of hydrogen peroxide in endothelial proliferative responses. Endothelium 9:231–238.
  • Tamura, K., B. Hua, S. Adachi, I. Guney, J. Kawauchi, M. Morioka, M. Tamamori-Adachi, Y. Tanaka, Y. Nakabeppu, M. Sunamori, J. M. Sedivy, and S. Kitajima. 2005. Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation. EMBO J. 24:2590–2601.
  • Uchida, Y., K. Ohba, T. Yoshioka, K. Irie, T. Muraki, and Y. Maru. 2004. Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway. J. Biol. Chem. 279:4075–4083.
  • Vasseur, S., G. V. Mallo, A. Garcia-Montero, E. M. Ortiz, F. Fiedler, E. Canepa, S. Moreno, and J. L. Iovanna. 1999. Structural and functional characterization of the mouse p8 gene: promotion of transcription by the CAAT-enhancer binding protein α (C/EBPα) and C/EBPβ trans-acting factors involves a C/EBP cis-acting element and other regions of the promoter. Biochem. J. 343:377–383.
  • Vasseur, S., A. Hoffmeister, A. Garcia-Montero, G. V. Mallo, R. Feil, S. Kühbandner, J. C. Dagorn, and J. L. Iovanna. 2002. p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis. Oncogene 21:1685–1694.
  • Volpert, O. V., R. Pili, H. A. Sikder, T. Nelius, T. Zaichuk, C. Morris, C. B. Shiflett, M. K. Devlin, K. Conant, and R. M. Alani. 2002. Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1. Cancer Cell 2:473–483.
  • Wang, J., Y. Cao, and D. F. Steiner. 2003. Regulation of proglucagon transcription by activated transcription factor (ATF)3 and a novel isoform, ATF3b, through the cAMP-response element/ATF site of the proglucagon gene promoter. J. Biol. Chem. 278:32899–32904.
  • Yan, C., H. Wang, and D. D. Boyd. 2002. ATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent trans-activation of the collagenase promoter. J. Biol. Chem. 277:10804–10812.

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