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Article

TGIF Inhibits Retinoid Signaling

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Pages 990-1001 | Received 18 Apr 2005, Accepted 04 Nov 2005, Published online: 27 Mar 2023

REFERENCES

  • Allenby, G., R. Janocha, S. Kazmer, J. Speck, J. F. Grippo, and A. A. Levin. 1994. Binding of 9-cis-retinoic acid and all-trans-retinoic acid to retinoic acid receptors alpha, beta, and gamma. Retinoic acid receptor gamma binds all-trans-retinoic acid preferentially over 9-cis-retinoic acid. J. Biol. Chem. 269:16689–16695.
  • Bastien, J., and C. Rochette-Egly. 2004. Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene 328:1–16.
  • Bertolino, E., B. Reimund, D. Wildt-Perinic, and R. Clerc. 1995. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270:31178–31188.
  • Burglin, T. R. 1997. Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals. Nucleic Acids Res. 25:4173–4180.
  • Chambon, P. 1996. A decade of molecular biology of retinoic acid receptors. FASEB J. 10:940–954.
  • Chiang, C., Y. Litingtung, E. Lee, K. E. Young, J. L. Corden, H. Westphal, and P. A. Beachy. 1996. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383:407–413.
  • Egea, P. F., A. Mitschler, N. Rochel, M. Ruff, P. Chambon, and D. Moras. 2000. Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid. EMBO J. 19:2592–2601.
  • Gehring, W. J., M. Affolter, and T. Burglin. 1994. Homeodomain proteins. Annu. Rev. Biochem. 63:487–526.
  • Glass, C. K., and M. G. Rosenfeld. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14:121–141.
  • Golden, J. A. 1998. Holoprosencephaly: a defect in brain patterning. J. Neuropathol. Exp. Neurol. 57:991–999.
  • Gripp, K. W., D. Wotton, M. C. Edwards, E. Roessler, L. Ades, P. Meinecke, A. Richieri-Costa, E. H. Zackai, J. Massague, M. Muenke, and S. J. Elledge. 2000. Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination. Nat. Genet. 25:205–208.
  • Hayhurst, M., and S. K. McConnell. 2003. Mouse models of holoprosencephaly. Curr. Opin. Neurol. 16:135–141.
  • Heldin, C.-H., K. Miyazono, and P. ten Dijke. 1997. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390:465–471.
  • Heyman, R. A., D. J. Mangelsdorf, J. A. Dyck, R. B. Stein, G. Eichele, R. M. Evans, and C. Thaller. 1992. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 68:397–406.
  • Hoberg, J. E., F. Yeung, and M. W. Mayo. 2004. SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival. Mol. Cell 16:245–255.
  • Khorasanizadeh, S., and F. Rastinejad. 2001. Nuclear-receptor interactions on DNA-response elements. Trends Biochem. Sci. 26:384–390.
  • Lammer, E. J., D. T. Chen, R. M. Hoar, N. D. Agnish, P. J. Benke, J. T. Braun, C. J. Curry, P. M. Fernhoff, A. W. Grix, Jr., I. T. Lott, et al. 1985. Retinoic acid embryopathy. N. Engl. J. Med. 313:837–841.
  • Leid, M., P. Kastner, R. Lyons, H. Nakshatri, M. Saunders, T. Zacharewski, J. Y. Chen, A. Staub, J. M. Garnier, S. Mader, et al. 1992. Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell 68:377–395.
  • Levin, A. A., L. J. Sturzenbecker, S. Kazmer, T. Bosakowski, C. Huselton, G. Allenby, J. Speck, C. Kratzeisen, M. Rosenberger, A. Lovey, et al. 1992. 9-cis retinoic acid stereoisomer binds and activates the nuclear receptor RXR alpha. Nature 355:359–361.
  • Liu, Y., M. Festing, J. C. Thompson, M. Hester, S. Rankin, H. M. El-Hodiri, A. M. Zorn, and M. Weinstein. 2004. Smad2 and Smad3 coordinately regulate craniofacial and endodermal development. Dev. Biol. 270:411–426.
  • Massagué, J. 1998. TGFβ signal transduction. Annu. Rev. Biochem. 67:753–791.
  • Massagué, J., A. Hata, and F. Liu. 1997. TGFβ signaling through the Smad pathway. Trends Cell Biol. 7:187–192.
  • Massagué, J., and D. Wotton. 2000. Transcriptional control by the TGF-beta/Smad signaling system. EMBO J. 19:1745–1754.
  • McGinnis, W., R. L. Garber, J. Wirz, A. Kuroiwa, and W. J. Gehring. 1984. A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans. Cell 37:403–408.
  • McGinnis, W., M. S. Levine, E. Hafen, A. Kuroiwa, and W. J. Gehring. 1984. A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes. Nature 308:428–433.
  • Melhuish, T. A., C. M. Gallo, and D. Wotton. 2001. TGIF2 interacts with histone deacetylase 1 and represses transcription. J. Biol. Chem. 276:32109–32114.
  • Melhuish, T. A., and D. Wotton. 2000. The interaction of C-terminal binding protein with the Smad corepressor TG-interacting factor is disrupted by a holoprosencephaly mutation in TGIF. J. Biol. Chem. 275:39762–39766.
  • Ming, J. E., and M. Muenke. 2002. Multiple hits during early embryonic development: digenic diseases and holoprosencephaly. Am. J. Hum. Genet. 71:1017–1032.
  • Muenke, M., and P. A. Beachy. 2000. Genetics of ventral forebrain development and holoprosencephaly. Curr. Opin. Genet. Dev. 10:262–269.
  • Nomura, M., and E. Li. 1998. Smad2 role in mesoderm formation, left-right patterning and craniofacial development. Nature 393:786–790.
  • Passner, J. M., H. D. Ryoo, L. Shen, R. S. Mann, and A. K. Aggarwal. 1999. Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature 397:714–719.
  • Pavri, R., B. Lewis, T. K. Kim, F. J. Dilworth, H. Erdjument-Bromage, P. Tempst, G. de Murcia, R. Evans, P. Chambon, and D. Reinberg. 2005. PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Mol. Cell 18:83–96.
  • Pendaries, V., F. Verrecchia, S. Michel, and A. Mauviel. 2003. Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner. Oncogene 22:8212–8220.
  • Piper, D. E., A. H. Batchelor, C.-P. Chang, M. L. Cleary, and C. Wolberger. 1999. Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation. Cell 96:587–597.
  • Rastinejad, F. 2001. Retinoid X receptor and its partners in the nuclear receptor family. Curr. Opin. Struct. Biol. 11:33–38.
  • Roessler, E., and M. Muenke. 1998. Holoprosencephaly: a paradigm for the complex genetics of brain development. J. Inherit. Metab. Dis. 21:481–497.
  • Rubenstein, J. L., and P. A. Beachy. 1998. Patterning of the embryonic forebrain. Curr. Opin. Neurobiol. 8:18–26.
  • Sapin, V., P. Bouillet, M. Oulad-Abdelghani, B. Dastugue, P. Chambon, and P. Dolle. 2000. Differential expression of retinoic acid-inducible (Stra) genes during mouse placentation. Mech. Dev. 92:295–299.
  • Seo, S. R., F. Lallemand, N. Ferrand, M. Pessah, S. L'Hoste, J. Camonis, and A. Atfi. 2004. The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation. EMBO J. 23:3780–3792.
  • Sharma, M., and Z. Sun. 2001. 5′TG3′ interacting factor interacts with Sin3A and represses AR-mediated transcription. Mol. Endocrinol. 15:1918–1928.
  • Shen, J., and C. A. Walsh. 2005. Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice. Mol. Cell. Biol. 25:3639–3647.
  • Sulik, K. K., D. B. Dehart, J. M. Rogers, and N. Chernoff. 1995. Teratogenicity of low doses of all-trans retinoic acid in presomite mouse embryos. Teratology 51:398–403.
  • Truett, G. E., P. Heeger, R. L. Mynatt, A. A. Truett, J. A. Walker, and M. L. Warman. 2000. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). BioTechniques 29:52, 54.
  • Umesono, K., K. K. Murakami, C. C. Thompson, and R. M. Evans. 1991. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell 65:1255–1266.
  • Wallis, D. E., and M. Muenke. 1999. Molecular mechanisms of holoprosencephaly. Mol. Genet. Metab. 68:126–138.
  • Wotton, D., P. S. Knoepfler, C. D. Laherty, R. N. Eisenman, and J. Massague. 2001. The Smad transcriptional corepressor TGIF recruits mSin3. Cell Growth Differ. 12:457–463.
  • Wotton, D., R. S. Lo, S. Lee, and J. Massague. 1999. A Smad transcriptional corepressor. Cell 97:29–39.
  • Wotton, D., R. S. Lo, L. A. Swaby, and J. Massague. 1999. Multiple modes of repression by the smad transcriptional corepressor TGIF. J. Biol. Chem. 274:37105–37110.
  • Wotton, D., and J. Massague. 2001. Smad transcriptional corepressors in TGF beta family signaling. Curr. Top. Microbiol. Immunol. 254:145–164.
  • Yanagisawa, J., Y. Yanagi, Y. Masuhiro, M. Suzawa, M. Watanabe, K. Kashiwagi, T. Toriyabe, M. Kawabata, K. Miyazono, and S. Kato. 1999. Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators. Science 283:1317–1321.
  • Zhang, Y., and R. Derynck. 1999. Regulation of Smad signaling by protein associations and signaling crosstalk. Trends Cell Biol. 9:274–279.

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