Overexpression of Transforming Growth Factor-β in Transgenic Mice Carrying the Human T-Cell Lymphotropic Virus Type I tax Gene

References

• Bascom, C. C., J. R. Wolfshohl, R. J. Coffey, Jr., L. Madison, N. R. Webb, A. R. Purchio, R. Derynck, and H. L. Moses. 1989. Complex regulation of transforming growth factor β1, β2, and β3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factor β1 and β2. Mol. Cell. Biol. 9:5508-5515.
   PubMed Web of Science ®Google Scholar
• Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
   PubMed Web of Science ®Google Scholar
• Church, G., and W. Gilbert. 1984. Genomic sequencing. Proc. Natl. Acad. Sci. USA 81:1991-1995.
   PubMed Web of Science ®Google Scholar
• Cross, S. L., M. B. Feinberg, J. B. Wolf, N. J. Holbrook, F. Wong-Staal, and W. J. Leonard. 1987. Regulation of the human interleukin-2 receptor chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I. Cell 49:47-56.
   PubMed Web of Science ®Google Scholar
• Danielpour, D., K. Y. Kim, L. L. Dart, S. Watanabe, A. B. Roberts, and M. B. Sporn. 1989. Sandwich enzyme-linked immunosorbent assays (SELISAs) quantitate and distinguish two forms of transforming growth factor-beta (TGF-β1 and TGF-β2) in complex biological fluids. Growth Factors 2:61-71.
   PubMed Web of Science ®Google Scholar
• Denhez, F., R. Lafyatis, P. Kondaiah, A. B. Roberts, and M. B. Sporn. 1990. Cloning by polymerase chain reaction of a new mouse TGF-β, mTGF-β3. Growth Factors 3:139-146.
   PubMed Web of Science ®Google Scholar
• Dvorak, H. F. 1986. Tumors: wounds that do not heal. N. Engl. J. Med. 315:1650-1659.
   PubMed Web of Science ®Google Scholar
• Felber, B. H., H. Paskalis, C. Kleinman-Ewing, F. Wong-Staal, and G. N. Pavlakis. 1985. The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats. Science 229:675-679.
   PubMed Web of Science ®Google Scholar
• Flanders, K. C., N. L. Thompson, D. S. Cissel, E. VanOb-berghen-Schilling, C. C. Baker, M. E. Kass, L. R. Ellingsworth, A. B. Roberts, and M. B. Sporn. 1989. Transforming growth factor-β1: histochemical localization with antibodies to different epitopes. J. Cell Biol. 108:653-660.
   PubMed Web of Science ®Google Scholar
• Fujii, M., P. Sassone-Corsi, and I. M. Verma. 1988. c-fos promoter trans-activation by the taxx protein of human T-cell leukemia virus type I. Proc. Natl. Acad. Sci. USA 85:8526-8530.
   PubMed Web of Science ®Google Scholar
• Geiser, A. G., S.-J. Kim, A. B. Roberts, and M. B. Sporn. 1991. Characterization of the mouse transforming growth factor-β1 promoter and activation by the Ha-ras oncogene. Mol. Cell. Biol. 11:84-92.
   PubMed Web of Science ®Google Scholar
• Green, J. E., C. G. Begley, D. K. Wagner, T. A. Waldmann, and G. Jay. 1989. trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene. Mol. Cell. Biol. 9:4731-4737.
   PubMed Web of Science ®Google Scholar
• Hinrichs, S. H., M. Nerenberg, R. K. Reynolds, G. Khoury, and G. Jay. 1987. A transgenic mouse model for human neurofibromatosis. Science 237:1340-1343.
   PubMed Web of Science ®Google Scholar
• Inoue, J., T. Seiki, T. Taniguchi, S. Tsuru, and M. Yoshida. 1986. Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1. EMBO J. 5:2883-2888.
   PubMed Web of Science ®Google Scholar
• Jeang, K.-T., R. Chiu, E. Santos, and S.-J. Kim. 1990. Oncoprotein Jun is a transcriptional activator of the HTLV-I long terminal repeat. Virology 181:218-227.
   Google Scholar
• Kim, S.-J., P. Angel, R. Lafyatis, K. Hattori, K. Y. Kim, M. B. Sporn, M. Karin, and A. B. Roberts. 1990. Autoinduction of transforming growth β1 is mediated by the AP-1 complex. Mol. Cell. Biol. 10:1492-1497.
   PubMed Web of Science ®Google Scholar
• Kim, S.-J., J. H. Kehrl, J. Burton, C. L. Tendler, K.-T. Jeang, D. Danielpour, C. Thevenin, K. Y. Kim, M. B. Sporn, and A. B. Roberts. 1990. Transactivation of the transforming growth factor β1 (TGF-β1) gene by human T-lymphotropic virus type 1 Tax: a potential mechanism for the increased production of TGF-β1 in adult T cell leukemia. J. Exp. Med. 172:121-129.
   PubMed Web of Science ®Google Scholar
• Marchall, G. Personal communication.
   Google Scholar
• Maruyama, M., H. Shibuya, H. Harada, M. Hatakeyama, M. Seiki, T. Fujita, J. Inoue, M. Yoshida, and T. Taniguchi. 1987. Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-l-encoded p40x and T3/Ti complex triggering. Cell 48:343-350.
   PubMed Web of Science ®Google Scholar
• Miller, D. A., A. Lee, Y. Matsui, E. Y. Chen, H. L. Moses, and R. Derynck. 1989. Complementary DNA cloning of the murine transforming growth factor-p3 (TGF-β3) precursor and the comparative expression of the TGF-β3 and TGF-β1 messenger RNA in murine embryos and adult tissues. Mol. Endocrinol. 3:1926-1934.
   PubMedGoogle Scholar
• Miller, D. A., A. Lee, R. W. Pelton, E. Y. Chen, H. L. Moses, and R. Derynck. 1989. Murine transforming growth factor β2 cDNA sequence and expression in adult tissues and embryos. Mol. Endocrinol. 3:1108-1114.
   PubMed Web of Science ®Google Scholar
• Miyatake, S., M. Seiki, R. D. Malefijt, T. Heike, J. Fujisawa, Y. Takebe, J. Nishida, J. Shlomai, T. Yokota, M. Yoshida, K. Arai, and N. Arai. 1988. Activation of T cell derived lymphokine genes in T cells and fibroblasts: effects of human T cell leukemia virus type I p40x protein and bovine papilloma virus encoded E2 protein. Nucleic Acids Res. 16:6547-6566.
   PubMed Web of Science ®Google Scholar
• Miyatake, S., M. Seiki, M. Yoshida, and K. Arai. 1988. T-cell activation signals and human T-cell leukemia virus type I-en- coded p40x protein activate the mouse granulocyte-macrophage colony-stimulating factor gene through a common DNA element. Mol. Cell. Biol. 8:5581-5587.
   PubMed Web of Science ®Google Scholar
• Nerenberg, M., S. H. Hinrichs, R. K. Reynolds, G. Khoury, and G. Jay. 1987. The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice. Science 237:1324-1329.
   PubMed Web of Science ®Google Scholar
• Niitsu, Y., Y. Urushizaki, Y. Koshida, K. Terui, Y. Mahara, Y. Kohgo, and I. Urushizaki. 1988. Expression of the TGF-β gene in adult T cell leukemia. Blood 71:263-267.
   PubMed Web of Science ®Google Scholar
• Poiesz, B. J., F. W. Ruscetti, A. F. Gazdar, P. A. Bunn, J. D. Minna, and R. C. Gallo. 1980. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc. Natl. Acad. Sci. USA 77:7415-7419.
   PubMed Web of Science ®Google Scholar
• Qian, S. W., P. Kondaiah, A. B. Roberts, and M. B. Sporn. 1990. cDNA cloning by PCR of rat transforming growth factor β-1. Nucleic Acids Res. 18:3059.
   PubMed Web of Science ®Google Scholar
• Roberts, A. B., K. C. Flanders, P. Kondaiah, N. L. Thomson, E. Van Obberghen-Schilling, L. Wakefield, P. Rossi, B. De Crombrugghe, U. Heine, and M. B. Sporn. 1988. Transforming growth factor β: biochemistry and roles in embryogenesis, tissue repair and remodeling, and carcinogenesis. Recent Prog. Horm. Res. 44:157-197.
   PubMedGoogle Scholar
• Ruscetti, F. W. Personal communication.
   Google Scholar
• Schuh, A. C., S. J. Keating, F. S. Monteclaro, P. K. Vogt, and M. L. Breitman. 1990. Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice. Nature (London) 346:756-761.
   PubMed Web of Science ®Google Scholar
• Siekevitz, M., M. B. Feinberg, N. Holbrook, F. Wong-Staal, and W. C. Greene. 1987. Activation of interleukin 2 and interleukin 2 receptor (tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Proc. Natl. Acad. Sci. USA 84:5389-5393.
   PubMed Web of Science ®Google Scholar
• Thompson, N. L., K. C. Flanders, J. M. Smith, L. R. Ellingsworth, A. B. Roberts, and M. B. Sporn. 1989. Expression of transforming growth factor-pi in specific cells and tissues of adult and neonatal mice. J. Cell Biol. 108:661-669.
   PubMed Web of Science ®Google Scholar
• Van Obberghen-Schilling, E., N. S. Roche, K. C. Flanders, M. B. Sporn, and A. B. Roberts. 1988. Transforming growth factor β1 positively regulates its own expression in normal and transformed cells. J. Biol. Chem. 263:7741-7746.
   PubMed Web of Science ®Google Scholar
• Yoshida, M., I. Miyoshi, and Y. Hinuma. 1982. Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc. Natl. Acad. Sci. USA 79:2031-2035.
   PubMed Web of Science ®Google Scholar