2
Views
9
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Domains Outside of the DNA-Binding Domain Impart Target Gene Specificity to Myogenin and MRF4

&
Pages 6103-6108 | Received 11 Jun 1991, Accepted 10 Sep 1991, Published online: 31 Mar 2023

REFERENCES

  • Braun, Τ., Ε. Bober, Β. Winter, Ν. Rosenthal, and Η. Η. Arnold. 1990. Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12? EMBO J. 9:821-831.
  • Braun, T., G. Buschhausen-Denker, E. Bober, E. Tannich, and Η. Η. Arnold. 1989. A novel human muscle factor related to but distinct from MyoDl induces myogenic conversion in 10T1/2 fibroblasts? EMBO J. 8:701-709.
  • Braun, T., V. Winter, E. Bober, and Η. Η. Arnold. 1990. Transcriptional activation domain of the muscle-specific gene regulatory protein myf5. Nature (London) 346:663-665.
  • Brennan, T., T. Chakraborty, and Ε. Ν. Olson. 1991. Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis. Proc. Natl. Acad. Sci. USA 88:5675-5679.
  • Brennan, T. J., and Ε. Ν. Olson. 1990. Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization. Genes Dev. 4:582-595.
  • Buskin, J. N., and S. D. Hauschka. 1989. Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene. Mol. Cell. Biol. 9:2627-2640.
  • Capetanaki, Y. (Baylor College of Medicine). Personal communication.
  • Chakraborty, T., T. J. Brennan, L. Li, D. Edmondson, and Ε. Ν. Olson. 1991. Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding. Mol. Cell. Biol. 11:3633-3641.
  • Chakraborty, Τ., Τ. J. Brennan, and Ε. Ν. Olson. 1991. Differential trans-activation of a muscle-specific enhancer by myogenic helix-loop-helix proteins is separable from DNA binding. J. Biol. Chem. 266:2878-2882.
  • Cserjesi, P., and Ε. Ν. Olson. 1991. Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products. Mol. Cell. Biol. 11:4854-4862.
  • Davis, R. L., P.-F. Cheng, A. B. Lassar, and H. Weintraub. 1990. The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation. Cell 60:733-746.
  • Davis, R. L., H. Weintraub, and A. B. Lassar. 1987. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51:987-1000.
  • Edmondson, D. G., and Ε. Ν. Olson. 1989. A gene with homology to the myc similarity region of MyoDl is expressed during myogenesis and is sufficient to activate the muscle differentiation program. Genes Dev. 3:628-640.
  • French, Β. Α., K.-L. Chow, E. N. Olson, and R. J. Schwartz. 1991. Heterodimers of myogenic helix-loop-helix regulatory factors and Ε12 bind a complex element governing myogenic induction of the avian cardiac α-actin promoter. Mol. Cell. Biol. 11:2439-2450.
  • Gossett, L. Α., D. J. Kelvin, E. A. Sternberg, and Ε. Ν. Olson. 1989. A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes. Mol. Cell. Biol. 9:5022-5033.
  • Jaynes, J. B., J. E. Johnson, J. N. Buskin, C. L. Gartside, and S. D. Hauschka. 1988. The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer. Mol. Cell. Biol. 8:62-70.
  • Lassar, A. B., J. N. Buskin, D. Lockshon, R. L. Davis, S. Apone, S. D. Hauschka, and H. Weintraub. 1989. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Cell 58:823-831.
  • Lin, H., K. E. Yutzey, and S. F. Konieczny. 1991. Muscle-specific expression of the troponin I gene requires interactions between helix-loop-helix muscle regulatory factors and ubiquitous transcription factors. Mol. Cell. Biol. 11:267-280.
  • Miner, J. H., and B. Wold. 1990. Herculin, a fourth member of the MyoD family of myogenic regulatory genes. Proc. Natl. Acad. Sci. USA 87:1089-1093.
  • Murre, C., P. S. McCaw, and D. Baltimore. 1989. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56:777-783.
  • Murre, C. P., P. S. McCaw, H. Vaessin, M. Caudy, L. Y. Jan, Y. N. Jan, C. V. Cabrera, J. N. Buskin, S. D. Hauschka, A. B. Lassar, H. Weintraub, and D. Baltimore. 1989. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 58:537-544.
  • Olson, Ε. Ν. 1990. MyoD family: a paradigm for development? Genes Dev. 4:1454-1461.
  • Piette, J., J.-L. Bessereau, M. Huchet, and J.-P. Changeaux. 1990. Two adjacent MyoDl binding sites regulate expression of the acetylcholine receptor alpha subunit. Nature (London) 345:353-355.
  • Rhodes, S. J., and S. F. Konieczny. 1989. Identification of MRF4: a new member of the muscle regulatory factor gene family. Genes Dev. 3:2050-2061.
  • Sartorelli, V., K. A. Webster, and L. Kedes. 1990. Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Spl. Genes Dev. 4:1811-1822.
  • Sassoon, D., G. Lyons, W. E. Wright, V. Lin, A. Lassar, H. Weintraub, and M. Buckingham. 1989. Expression of two myogenic regulatory factor genes, myogenin and MyoD1, during mouse embryogenesis. Nature (London) 341:303-307.
  • Schwarz, J., T. Chakraborty, J. Martin, J. Zhou, and L. Olson. Submitted for publication.
  • Sternberg, Ε. Α., and E. Olson. Unpublished results.
  • Sternberg, Ε. Α., G. Spizz, W. M. Perry, D. Vizard, T. Weil, and Ε. Ν. Olson. 1988. Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene. Mol. Cell. Biol. 8:2896-2909.
  • Tanaka, M., and W. Herr. 1990. Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation. Cell 60:375-386.
  • Tapscott, S. J., and H. Weintraub. 1991. MyoD and the regulation of myogenesis by helix-loop-helix proteins. J. Clin. Invest. 87:1133-1138.
  • Thayer, M. J., S. J. Tapscott, R. L. Davis, W. E. Wright, A. B. Lassar, and H. Weintraub. 1989. Positive autoregulation of the myogenic determination gene MyoDl. Cell 58:241-248.
  • Weintraub, H., R. Davis, D. Lockshon, and A. Lassar. 1990. MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation. Proc. Natl. Acad. Sci. USA 87:5623-5627.
  • Wentworth, B. M., M. Donoghue, J. C. Engert, Ε. Β. Berglund, and N. Rosenthal. 1991. Paired MyoD binding sites regulate myosin light chain gene expression. Proc. Natl. Acad. Sci. USA 88:1242-1246.
  • Wright, W. E., D. A. Sassoon, and V. K. Lin. 1989. Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD. Cell 56:607-617.
  • Yutzey, K. E., S. J. Rhodes, and S. F. Konieczny. 1990. Differential trans activation associated with the muscle regulatory factors MyoD1, myogenin, and MRF4. Mol. Cell. Biol. 10:3934-3944.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.