15
Views
17
CrossRef citations to date
0
Altmetric
Gene Expression

Interleukin-6 Signals Activating junB and TIS11 Gene Transcription in a B-Cell Hybridoma

&
Pages 1409-1418 | Received 06 Jul 1990, Accepted 12 Dec 1990, Published online: 31 Mar 2023

REFERENCES

  • Akiyama, T., J. Ishida, S. Nakagawa, H. Ogawara, S. Watanabe, N. Itoh, M. Shibuya, and Y. Fukami. 1987. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J. Biol. Chem. 262:5592-5595.
  • Anderson, N. G., J. L. Mailer, N. K. Tanks, and T. W. Sturgill. 1990. Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature (London) 343:651-653.
  • Angel, P., E. A. Allegretto, S. T. Okino, K. Hattori, W. J. Boyle, T. Hunter, and M. Karin. 1988. Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. Nature (London) 332:166-171.
  • Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49:729-739.
  • Bohmann, D., T. Bos, A. Admon, T. Nishimura, P. K. Vogt, and R. Tjian. 1987. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science 238:1386-1392.
  • Chavier, P., M. Zerial, P. Lemaire, J. Almendral, R. Bravo, and P. Charnay. 1988. A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells. EMBO J. 7:29-35.
  • Chiu, C.-P., C. Moulds, R. L. Coffman, D. Rennick, and F. Lee. 1988. Multiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells. Proc. Natl. Acad. Sci. USA 85:7099-7103.
  • Chiu, R., W. J. Boyle, J. Meek, T. Smeal, T. Hunter, and M. Karin. 1988. The c-fos protein interacts with c-jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54:541-552.
  • Christy, B. A., L. F. Lau, and D. Nathans. 1988. A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with ‘zinc finger’ sequences. Proc. Natl. Acad. Sci. USA 85:7857-7861.
  • Cohen, D. R., and T. Curran. 1988. fra-1, a serum-inducible, cellular immediate early gene that encodes a fos-related antigen. Mol. Cell. Biol. 8:2063-2069.
  • Coulie, P., A. Vanhecke, J. Van Damme, S. Cayphas, P. Poupart, L. Dewit, and J. Content. 1987. High affinity binding sites for human 26-kDa protein (interleukin 6, B cell stimulatory factor-2, human hybridoma plasmacytoma growth factor, interferon-β2), different from those of type 1 interferon (α, β), on lymphoblastoid cells. Eur. J. Immunol. 17:1435-1440.
  • Curran, T., G. Peters, C. Van Bevereren, N. M. Teich, and I. M. Verma. 1982. FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. J. Virol. 44:674-682.
  • Frackelton, J. A. R., P. M. Tremble, and L. T. Williams. 1984. Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo immunopurification using a monoclonal antibody to phosphotyrosine. J. Biol. Chem. 259:7909-7915.
  • Garman, R. D., K. A. Jacobs, S. C. Clark, and D. H. Raulet. 1987. B-cell stimulatory factor 2 (β2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells. Proc. Natl. Acad. Sci. USA 84:7629-7633.
  • Gauldie, J., C. Richards, D. Harnish, P. Lansdorp, and H. Baumann. 1987. Interferon β2/BSF-2 shares identity with monocyte derived hepatocyte stimulating factor (HSF) and regulates the major acute phase protein response in liver cells. Proc. Natl. Acad. Sci. USA 84:7241-7255.
  • Haegeman, G., J. Content, G. Volckaert, R. Deryhnck, J. Tavernier, and W. Fiers. 1986. Structural analysis of the sequence coding for an inducible 26-kd protein in human fibroblasts. Eur. J. Biochem. 159:625-632.
  • Hannun, Y. A., C. R. Loomis, J. A. H. Merrill, and R. M. Bell. 1986. Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J. Biol. Chem. 261:12604-12609.
  • Harpold, M. M., R. M. Evance, M. Salditt-Georgieff, and J. E. Darnell. 1979. Production of mRNA in Chinese hamster cells: relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences. Cell 17:1025-1035.
  • Hazel, T. G., D. Nathans, and L. F. Lau. 1988. A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. Proc. Natl. Acad. Sci. USA 85:8444-8448.
  • Hidaka, H., Y. Sasaki, T. Tanaka, T. Endo, S. Ohno, Y. Fuji, and T. Nagata. 1981. N-(6-Aminohexyl)-5-chloronaphthalene- sulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc. Natl. Acad. Sci. USA 78:4354-4357.
  • Hirano, T., T. Taga, N. Nakano, K. Yasukawa, S. Kashiwamura, K. Shimizu, K. Nakajima, K. H. Pyun, and T. Kishimoto. 1985. Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2). Proc. Natl. Acad. Sci. USA 82:5490-5494.
  • Hirano, T., K. Yasukawa, H. Harada, T. Taga, Y. Watanabe, T. Matsuda, S. Kashiwamura, K. Nakajima, K. Koyama, A. Iwamatsu, S. Tsunasawa, F. Sakiyama, H. Matsui, Y. Takahara, and T. Taniguchi. 1986. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature (London) 324:73-76.
  • Huhn, R. D., M. R. Posner, S. I. Rayter, J. G. Foulkes, and J. A. R. Frackelton. 1987. Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues. Proc. Natl. Acad. Sci. USA 84:4408-4412.
  • Ikebuchi, K., G. G. Wong, S. C. Clark, J. N. Ihle, Y. Hirai, and M. Ogawa. 1987. Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc. Natl. Acad. Sci. USA 84:9035-9039.
  • Jamal, S., and E. Ziff. 1990. Transactivation of c-fos and β-actin genes by raf as a step in early response to transmembrane signals. Nature (London) 344:463-466.
  • Kamps, M. P., and B. M. Sefton. 1988. Identification of multiple novel polypeptide substrates of the V-src, V-yes, V-jps, V-ros, and V-erb-β oncogenic tyrosine protein kinases utilizing antisera against phosphotyrosine. Oncogene 2:305-315.
  • Kawano, M., T. Hirano, T. Matsuda, Y. Horii, K. Iwato, H. Asaoku, B. Tang, O. Tanabe, H. Tanaka, A. Kuramoto, and T. Kishimoto. 1988. Autocrine generation and requirement of BSF- 2/IL-6 for human multiple myelomas. Nature (London) 332:83-85.
  • Kishimoto, T., and T. Hirano. 1988. Molecular regulation of B lymphocyte response. Annu. Rev. Immunol. 6:485-512.
  • Lee, W., P. Mitchell, and R. Tjian. 1987. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49:741-752.
  • Lemaire, P., O. Relevant, R. Bravo, and P. Charnay. 1988. Two genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells. Proc. Natl. Acad. Sci. USA 85:4691-4695.
  • Lim, R. W., B. C. Varnum, and H. R. Herschman. 1987. Cloning of tetradecanoyl phorbol ester-induced “primary response” sequences and their expression in density-arrested Swiss 3T3 cells and a TPA nonproliferative variant. Oncogene 1:263-270.
  • Lotz, M., F. Jirik, P. Kabouridis, C. Tsoukas, T. Hirano, T. Kishimoto, and D. A. Carson. 1988. B-cell stimulating factor/ interleukin 6 is a co-stimulant for human thymocytes and T lymphocytes. J. Exp. Med. 167:1253-1258.
  • Lüscher, R., E. A. Kuenzel, E. G. Krebs, and R. N. Eisenman. 1989. Myc oncoproteins are phosphorylated by casein kinase II. EMBO J. 8:1111-1119.
  • Lyall, R., A. Ziberstein, A. Gazit, R. Gilon, A. Levitzki, and J. Schlessinger. 1989. Tyrphostins inhibit EGF receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation. J. Biol. Chem. 264:14503-14509.
  • Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Matsuda, T., T. Hirano, and T. Kishimoto. 1988. Establishment of interleukin 6 (IL-6) B cell stimulatory factor 2 (BSF-2)- dependent cell line and preparation of anti-IL-6/BSF-2 monoclonal antibodies. Eur. J. Immunol. 18:951-956.
  • Milbrandt, J. 1987. A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. Science 238:797-799.
  • Miyaura, C., K. Onozaki, Y. Akiyama, T. Taniyama, T. Hirano, T. Kishimoto, and T. Suda. 1988. Recombinant human IL-6 (B-cell stimulatory factor 2) is a potent inducer of differentiation of mouse myeloid leukemia cells (M1). FEBS Lett. 234:17-21.
  • Muraguchi, A., T. Hirano, B. Tang, T. Matsuda, Y. Horii, K. Nakajima, and T. Kishimoto. 1988. The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells. J. Exp. Med. 167:332-344.
  • Nakabeppu, Y., K. Ryder, and D. Nathans. 1988. DNA binding activities of three murine jun proteins: stimulation by fos. Cell 55:907-915.
  • Nakajima, K. Unpublished data.
  • Nordan, R. P., and M. Potter. 1986. A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro. Science 233:566-569.
  • Okada, M., M. Kitahara, S. Kishimoto, T. Matsuda, T. Hirano, and T. Kishimoto. 1988. IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells. J. Immunol. 141:1543-1549.
  • Rapp, U. R., M. D. Goldsborough, G. E. Mark, T. I. Bonner, J. Groffen, F. H. Reynolds, and J. R. Stephenson. 1983. Structure and biological activity of raf-1, a unique oncogene transduced by a retrovirus. Proc. Natl. Acad. Sci. USA 80:4218-4222.
  • Ryder, K., L. F. Lau, and D. Nathans. 1988. A gene activated by growth factors is related to the oncogene v-jun. Proc. Natl. Acad. Sci. USA 85:1487-1491.
  • Sassone-Corsi, P., W. W. Lamph, M. Kamps, and I. M. Verma. 1988. fos-associated cellular p39 is related to nuclear transcription factor AP-1. Cell 54:553-560.
  • Satoh, T., S. Nakamura, T. Taga, T. Matsuda, T. Hirano, T. Kishimoto, and Y. Kaziro. 1988. Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin-6. Mol. Cell. Biol. 8:3546-3549.
  • Sengupta, A., W. K. Liu, Y. G. Yeung, J. A. R. Frackelton, and E. R. Stanley. 1988. Identification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1. Proc. Natl. Acad. Sci. USA 85:8062-8066.
  • Sommercern, J., J. A. Mulligan, F. J. Lozeman, and E. G. Krebs. 1987. Activation of casein kinase II in response to insulin and to epidermal growth factor. Proc. Natl. Acad. Sci. USA 84:8834-8838.
  • Sukhatme, V. P., X. Cao, L. C. Chang, C. H. Tsai-Morris, D. Stamenkovich, P. D. P. Ferreira, D. R. Cohen, S. A. Edwards, T. B. Shows, T. Curran, M. M. Le Beau, and E. D. Adamson. 1988. A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53:37-43.
  • Taga, T., M. Higi, Y. Hirata, K. Yamasaki, K. Yasukawa, T. Matsuda, T. Hirano, and T. Kishimoto. 1989. Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell 58:573-581.
  • Taga, T., Y. Kawanishi, R. R. Hardy, T. Hirano, and T. Kishimoto. 1987. Receptors for B cell stimulatory factor 2: quantitation, specificity, distribution, and regulation of their expression. J. Exp. Med. 166:967-981.
  • Takai, Y., G. G. Wong, S. C. Clark, S. J. Burakoff, and S. H. Herrmann. 1988. B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes. J. Immunol. 140:508-512.
  • Tirone, F., and E. M. Shooter. 1989. Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon- related gene. Proc. Natl. Acad. Sci. USA 86:2088-2092.
  • Tosato, G., K. B. Seamon, N. D. Goldman, P. B. Sehgal, L. T. May, G. C. Washington, K. D. Jones, and S. E. Pike. 1988. Monocyte-derived human B-cell growth factor identified as interferon-β2 (BSF-2, IL-6). Science 239:502-504.
  • Van Beveren, C., F. Van Staalen, T. Curran, R. Muller, and I. M. Verma. 1983. Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxyl termini. Cell 32:1241-1255.
  • Van Damme, J., G. Opdenakker, R. J. Simpson, M. R. Rubira, S. Cayphas, A. Vink, A. Billiau, and J. Van Snick. 1987. Identification of the human 26 kd protein, interferon β2 (IFN- β2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor. J. Exp. Med. 165:914-919.
  • Van Snick, J. 1990. Interleukin-6: an overview. Annu. Rev. Immunol. 8:253-278.
  • Varnum, B., R. Lum, V. Sukhatme, and H. Herschman. 1989. Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate. Oncogene 4:1263-1265.
  • Varnum, B. C., R. W. Lim, and H. R. Herschman. 1989. Characterization of TIS7, a gene induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate. Oncogene 4:119-120.
  • Wall, R., M. Briskin, C. Carter, H. Govan, A. Taylor, and P. Kincade. 1986. A labile inhibitor blocks immunoglobulin κ-light- chain-gene transcription in a pre-B leukemic cell line. Proc. Natl. Acad. Sci. USA 83:295-298.
  • Wasylyk, C., B. Wasylyk, G. Heidecker, M. Huleihel, and U. R. Rapp. 1989. Expression of raf oncogenes activates the PEA1 transcription factor motif. Mol. Cell. Biol. 9:2247-2250.
  • Yaish, P., A. Gazit, C. Gilon, and C. Levitzki. 1988. Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors. Science 242:933-935.
  • Yamasaki, K., T. Taga, Y. Hirata, H. Yawata, Y. Kawanishi, B. Seed, T. Taniguchi, T. Hirano, and T. Kishimoto. 1988. Cloning and expression of the human interleukin-6 (BSF-2/IFN-β2) receptor. Science 241:825-828.
  • Yarden, Y., and A. Ullrich. 1988. Growth factor receptor tyrosine kinases. Annu. Rev. Biochem. 57:443-478.
  • Zerial, M., L. Toschi, R.-P. Ryseck, M. Schuermann, R. Mueller, and R. Bravo. 1989. The product of a novel growth factor activated gene, fos-B, interacts with JUN proteins enhancing their DNA binding activity. EMBO J. 8:805-813.
  • Zilberstein, A., R. Ruggieri, J. H. Korn, and M. Revel. 1986. Structure and expression of cDNA and genes for human interferon-β2, a distinct species inducible by growth-stimulatory cytokines. EMBO J. 5:2529-2537.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.