Repression of hsp70 Heat Shock Gene Transcription by the Suppressor of Hairy-Wing Protein of Drosophila melanogaster

REFERENCES

• Amin, J., R. Mestril, R. Lawson, H. Klapper, and R. Voellmy. 1985. The heat shock consensus sequence is not sufficient for hsp70 gene expression in Drosophila melanogaster. Mol. Cell. Biol. 5:197–203.
   Google Scholar
• Biessman, H. 1985. Molecular analysis of the yellow gene (y) region of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 82:7369–7373.
   PubMedGoogle Scholar
• Campuzano, S., L. Balcells, R. Villares, L. Carramolino, L. Garcia-Alonso, and J. Modolell. 1986. Excess function Hairywing mutations caused by gypsy and copia insertions within structural genes of the achaete-scute locus of Drosophila. Cell 44:303–312.
   PubMed Web of Science ®Google Scholar
• Cohen, R. S., and M. Meselson. 1984. Inducible transcription and puffing in Drosophila melanogaster transformed with hsp70-phage X hybrid heat shock genes. Proc. Natl. Acad. Sci. USA 81:5509–5513.
   PubMedGoogle Scholar
• Cohen, R. S., and M. Meselson. 1988. Periodic interactions of heat shock transcriptional elements. Nature (London) 332:856–858.
   PubMedGoogle Scholar
• Dorsett, D., C. Liu, and J. Jack. Unpublished data.
   Google Scholar
• Dorsett, D., G. A. Viglianti, B. J. Rutledge, and M. Meselson. 1989. Alteration of hsp82 gene expression by the gypsy transposon and suppressor genes in Drosophila melanogaster. Genes Dev. 3:454—468.
   PubMedGoogle Scholar
• Dorsett, D. 1990. Potentiation of a polyadenylylation site by a downstream protein-DNA interaction. Proc. Natl. Acad. Sci. USA 87:4373–4377.
   PubMedGoogle Scholar
• Dudler, R., and A. A. Travers. 1984. Upstream elements necessary for optimal function of the hsp70 promoter in transformed flies. Cell 38:391–398.
   PubMed Web of Science ®Google Scholar
• Dunn, T., S. Hahn, S. Ogden, and R. Schleif. 1984. An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression. Proc. Natl. Acad. Sci. USA 81:5017–5020.
   PubMed Web of Science ®Google Scholar
• Fischer, J. A., and T. Maniatis. 1988. Drosophila Adh: a promoter element expands the tissue specificity of an enhancer. Cell 53:451–461.
   PubMedGoogle Scholar
• Garabedian, M. J., B. M. Shepherd, and P. C. Wensink. 1986. A tissue-specific transcription enhancer from the Drosophila yolk protein 1 gene. Cell 45:859–867.
   PubMed Web of Science ®Google Scholar
• Geyer, P. K., C. Spana, and V. G. Corces. 1986. On the molecular mechanism of gypsy-induced mutations at the yellow locus of Drosophila melanogaster. EMBO J. 5:2657–2662.
   PubMed Web of Science ®Google Scholar
• Geyer, P., and V. G. Corces. 1987. Separate regulatory elements are responsible for the complex pattern of tissue-specific and developmental transcription of the yellow locus in Drosophila melanogaster. Genes Dev. 1:996–1004.
   PubMed Web of Science ®Google Scholar
• Geyer, P. K., M. M. Green, and V. G. Corces. 1988. Reversion of a gypsy-induced mutation at the yellow (y) locus of Drosophila melanogaster is associated with the insertion of a newly defined transposable element. Proc. Natl. Acad. Sci. USA 85:3938–3942.
   PubMedGoogle Scholar
• Geyer, P. K., M. M. Green, and V. G. Corces. 1990. Tissuespecific transcriptional enhancers may act in trans on the gene located in the homologous chromosome: the molecular basis of transvection in Drosophila. EMBO J. 9:2247–2256.
   PubMed Web of Science ®Google Scholar
• Gill, G., and M. Ptashne. 1988. Negative effect of the transcriptional activator GAL4. Nature (London) 334:721–724.
   PubMed Web of Science ®Google Scholar
• Glaser, R. L., and J. T. Lis. 1990. Multiple, compensatory regulatory elements specify spermatocyte-specific expression of the Drosophila melanogaster hsp26 gene. Mol. Cell. Biol. 10:131–137.
   PubMedGoogle Scholar
• Han, K., M. S. Levine, and J. L. Manley. 1989. Synergistic activation and repression of transcription by Drosophila ho- meobox proteins. Cell 56:573–583.
   PubMedGoogle Scholar
• Hiromi, Y., and W. J. Gehring. 1987. Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell 50:963–974.
   PubMedGoogle Scholar
• Hoch, M., C. Schroder, E. Seifert, and H. Jackie. 1990. exacting control elements for Krüppel expression in the Drosophila embryo. EMBO J. 9:2587–2595.
   PubMedGoogle Scholar
• Jack, J. W. 1985. Molecular organization of the cut locus of Drosophila melanogaster. Cell 42:869–876.
   PubMedGoogle Scholar
• Jaynes, J. B., and P. H. O’Farrell. 1988. Activation and repression of transcription by homeodomain-containing proteins that bind a common site. Nature (London) 336:744–749.
   PubMedGoogle Scholar
• Jaynes, J. B., and P. H. O’Farrell. Personal communication.
   Google Scholar
• Keleher, C. A., C. Goutte, and A. D. Johnson. 1988. The yeast cell-type-specific repressor α2 acts cooperatively with a noncell-type-specific protein. Cell 53:927–936.
   PubMedGoogle Scholar
• Klug, A., and D. Rhodes. 1987. ‘Zinc fingers’: a novel protein motif for nucleic acid recognition. Trends Biochem. Sci. 12:464–469.
   Web of Science ®Google Scholar
• Levine, M., and J. L. Manley. 1989. Transcriptional repression of eukaryotic promoters. Cell 59:405–408.
   PubMedGoogle Scholar
• Modolell, J., W. Bender, and M. Meselson. 1983. Drosophila melanogaster mutations suppressible by the suppressor of Hairy-wing are insertions of a 7.3-kilobase mobile element. Proc. Natl. Acad. Sci. USA 80:1678–1682.
   PubMedGoogle Scholar
• Parker, C. S., and J. Topol. 1984. A Drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene. Cell 37:273–283.
   PubMed Web of Science ®Google Scholar
• Parkhurst, S. M., and V. G. Corces. 1985. forked, gypsys, and suppressors in Drosophila. Cell 41:429–437.
   Google Scholar
• Parkhurst, S. M., D. A. Harrison, M. P. Remington, C. Spana, R. L. Kelley, R. S. Coyne, and V. G. Corces. 1988. The Drosophila su(Hw) gene, which controls the phenotypic effect of the gypsy transposable element, encodes a putative DNA- binding protein. Genes Dev. 2:1205–1215.
   PubMedGoogle Scholar
• Pelham, H. R. B., and M. Bienz. 1982. A synthetic heat shock promoter element confers heat inducibility on the herpes simplex virus thymidine kinase gene. EMBO J. 1:1473–1477.
   PubMed Web of Science ®Google Scholar
• Perisic, O., H. Xiao, and J. T. Lis. 1989. Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit. Cell 59:797–806.
   PubMed Web of Science ®Google Scholar
• Pick, L., A. Schier, M. Affolter, T. Schmidt-Glenewinkel, and W. J. Gehring. 1990. Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated. Genes Dev. 4:1224–1239.
   PubMedGoogle Scholar
• Proudfoot, N. J. 1986. Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation. Nature (London) 322:562–565.
   PubMed Web of Science ®Google Scholar
• Ptashne, M. 1986. Gene regulation by proteins acting nearby and at a distance. Nature (London) 322:697–701.
   PubMed Web of Science ®Google Scholar
• Rubin, G. M., and A. C. Spradling. 1983. Vectors for P element-mediated gene transfer in Drosophila. Nucleic Acids Res. 11:6341–6351.
   PubMed Web of Science ®Google Scholar
• Rutledge, B. J., M. A. Mortin, E. Schwarz, D. Thierry-Mieg, and M. Meselson. 1988. Genetic interactions of modifier genes and modifiable alleles in Drosophila melanogaster. Genetics 119: 391–397.
   PubMedGoogle Scholar
• Sauer, R. T., D. L. Smith, and A. D. Johnson. 1988. Domain structure, subunit organization, and operator-binding features of the yeast repressor α2. Genes Dev. 2:807–816.
   PubMedGoogle Scholar
• Shuey, D. J., and C. S. Parker. 1986. Binding of Drosophila heat-shock gene transcription factor to the hsp 70 promoter. J. Biol. Chem. 261:7934–7940.
   PubMedGoogle Scholar
• Simon, J. A., and J. T. Lis. 1987. A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements. Nucleic Acids. Res. 15:2971–2988.
   PubMed Web of Science ®Google Scholar
• Simon, J. A., C. A. Sutton, R. B. Lobell, R. L. Glaser, and J. T. Lis. 1985. Determinants of heat shock-induced chromosome puffing. Cell 40:805–817.
   PubMedGoogle Scholar
• Spana, C., D. A. Harrison, and V. G. Corces. 1988. The Drosophila melanogaster suppressor of Hairy-wing protein binds to specific sequences of the gypsy retrotransposon. Genes Dev. 2:1414–1423.
   PubMedGoogle Scholar
• Topol, J., D. M. Ruden, and C. S. Parker. 1985. Sequences required for in vitro transcriptional activation of a Drosophila hsp 70 gene. Cell 42:527–537.
   PubMed Web of Science ®Google Scholar
• Vincent, J.-P., J. A. Kassis, and P. H. O’Farrell. 1990. A synthetic homeodomain binding site acts as a cell type specific, promoter specific enhancer in Drosophila embryos. EMBO J. 9:2573–2578.
   PubMedGoogle Scholar
• Wiederrecht, G., D. J. Shuey, W. A. Kibbe, and C. S. Parker. 1987. The Saccharomyces and Drosophila heat-shock transcription factors are identical in size and DNA binding properties. Cell 48:507–515.
   PubMedGoogle Scholar
• Wu, C. 1984. Two protein-binding sites in chromatin implicated in the activation of heat shock genes. Nature (London) 309:229–234.
   PubMed Web of Science ®Google Scholar
• Wu, C., S. Wilson, B. Walker, I. Dawid, T. Paisley, V. Zimarino, and H. Ueda. 1987. Purification and properties of Drosophila heat-shock activator protein. Science 238:1247–1253.
   PubMed Web of Science ®Google Scholar
• Xiao, H., and J. T. Lis. 1988. Germline transformation used to define key features of heat shock response elements. Science 239:1139–1142.
   PubMed Web of Science ®Google Scholar