Dominant Positive and Negative Selection Using a Hygromycin Phosphotransferase-Thymidine Kinase Fusion Gene

References

• Bender, M. A., T. D. Palmer, R. E. Gelinas, and A. D. Miller. 1987. Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region. J. Virol. 61:1639-1646.
   PubMed Web of Science ®Google Scholar
• Besnard, C., E. Monthioux, and J. Jami. 1987. Selection against expression of the Escherichia coli gene gpt in hprt+ mouse teratocarcinoma and hybrid cells. Mol. Cell. Biol. 7:4139-4141.
   PubMed Web of Science ®Google Scholar
• Boshart, M., F. Weber, G. Jahn, K. Dorsch-Hasler, B. Fleckenstein, and W. Schaffner. 1985. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41:521-530.
   PubMed Web of Science ®Google Scholar
• Colbere-Garapin, F., F. Horodniceanu, P. Kourilsky, and A. C. Garapin. 1981. A new dominant hybrid selective marker for higher eukaryotic cells. J. Mol. Biol. 150:1-14.
   PubMed Web of Science ®Google Scholar
• Fenwick, R. G. 1985. The HGPRT system, p. 333-373. In M. Gottesman (ed.), Molecular cell genetics. John Wiley & Sons, Inc., New York.
   Google Scholar
• Haarr, L., H. S. Marsden, C. M. Preston, J. R. Smiley, W. C. Summers, and W. P. Summers. 1985. Utilization of internal AUG codons for initiation of protein synthesis directed by mRNAs from normal and mutant genes encoding herpes simplex virus-specified thymidine kinase. J. Virol. 56:512-519.
   PubMedGoogle Scholar
• Heyman, R. A., E. Borrelli, J. Lesley, D. Anderson, D. D. Richman, S. M. Baird, R. Hyman, and R. M. Evans. 1989. Thymidine kinase obliteration: creation of transgenic mice with controlled immune deficiency. Proc. Natl. Acad. Sci. USA 86:2698-2702.
   PubMed Web of Science ®Google Scholar
• Jolly, D., H. Okayama, P. Berg, A. C. Esty, D. Filpula, P. Bohlen, G. G. Johnson, J. E. Shively, T. Hunkapillar, and T. Friedmann. 1983. Isolation and characterization of a full length expression cDNA for human hypoxanthine phosphoribosyl-transferase. Proc. Natl. Acad. Sci. USA 80:477-481.
   PubMed Web of Science ®Google Scholar
• Kasid, A., S. Morecki, P. Aebersold, K. Cornetta, K. Culver, S. Freeman, E. Director, M. T. Lotze, R. M. Blaese, W. F. Anderson, and S. A. Rosenberg. 1990. Human gene transfer: characterization of human tumor-infiltrating lymphocytes as vehicles for retroviral-mediated gene transfer in man. Proc. Natl. Acad. Sci. USA 87:473-477.
   PubMed Web of Science ®Google Scholar
• Kaster, K. R., G. Burgett, R. N. Rao, and T. D. Ingolia. 1983. Analysis of bacterial hygromycin B resistance gene by transcriptional and translational fusions and by DNA sequencing. Nucleic Acids Res. 11:6895-6911.
   PubMedGoogle Scholar
• Kozak, M. 1987. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:8125-8148.
   PubMed Web of Science ®Google Scholar
• Lusky, M., and M. Botchan. 1981. Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature (London) 293:79-81.
   PubMedGoogle Scholar
• Mann, R., R. C. Mulligan, and D. Baltimore. 1983. Construction of a retrovirus packaging mutant and its use to produce helper-free retrovirus. Cell 33:153-159.
   PubMed Web of Science ®Google Scholar
• Miller, A. D., and C. Buttimore. 1986. Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol. Cell. Biol. 6:2895-2902.
   PubMed Web of Science ®Google Scholar
• Moolten, F. L., and J. M. Wells. 1990. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J. Natl. Cancer Inst. 82:297-300.
   PubMed Web of Science ®Google Scholar
• Moolten, F. L., J. M. Wells, R. A. Heyman, and R. M. Evans. 1990. Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene. Hum. Gene Ther. 1:125-134.
   PubMed Web of Science ®Google Scholar
• Mulligan, R. C., and P. Berg. 1981. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proc. Natl. Acad. Sci. USA 78:2072-2076.
   PubMed Web of Science ®Google Scholar
• Overell, R. W., K. E. Weisser, and D. Cosman. 1988. Stably transmitted triple-promoter retroviral vectors and their use in transformation of primary mammalian cells. Mol. Cell. Biol. 8:1803-1808.
   PubMed Web of Science ®Google Scholar
• Rosenberg, S. A., P. Aebersold, K. Cornetta, A. Kasid, R. A. Morgan, R. Moen, E. M. Karson, M. T. Lotze, J. C. Yang, S. L. Topalian, M. J. Merino, K. Culver, A. D. Miller, R. M. Blaese, and W. F. Anderson. 1990. Gene transfer into humans: immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. N. Engl. J. Med. 323:570-578.
   PubMed Web of Science ®Google Scholar
• Santerre, R. F., N. E. Allen, J. N. Hobbs, R. N. Rao, and R. J. Schmidt. 1984. Expression of prokaryotic genes for hygromycin B and G418 resistance as dominant-selection markers in mouse L cells. Gene 30:147-156.
   PubMedGoogle Scholar
• Shinnick, T. M., R. A. Lerner, and J. G. Sutcliffe. 1981. Nucleotide sequence of Moloney murine leukaemia virus. Nature (London) 293:543-548.
   PubMed Web of Science ®Google Scholar
• St. Clair, M. H., C. U. Lambe, and P. A. Furman. 1987. Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information. Antimicrob. Agents Chemother. 31:844-849.
   PubMed Web of Science ®Google Scholar
• Taylor, M. W., A. E. Simon, and R. M. Kothari. 1985. The APRT system, p. 311-332. In M. Gottesman (ed.), Molecular cell genetics. John Wiley & Sons, Inc., New York.
   Google Scholar
• Tooze, J. (ed.). 1981. Molecular biology of tumor viruses, 2nd ed. DNA tumor viruses. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Topp, W. C. 1981. Normal rat cell lines deficient in nuclear thymidine kinase. Virology 113:408-411.
   PubMed Web of Science ®Google Scholar
• Van Beveren, C., F. van Straeten, J. A. Galleshaw, and I. M. Verma. 1981. Nucleotide sequence of the genome of a murine sarcoma virus. Cell 27:97-108.
   PubMed Web of Science ®Google Scholar
• Wagner, M. J., J. A. Sharp, and W. C. Summers. 1981. Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1. Proc. Natl. Acad. Sci. USA 78:1441-1445.
   PubMed Web of Science ®Google Scholar
• Wigler, M., A. Pellicer, S. Suverstein, R. Axel, G. Urlaub, and L. Chasin. 1979. DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells. Proc. Natl. Acad. Sci. USA 76:1373-1376.
   PubMed Web of Science ®Google Scholar
• Wigler, M., S. Suverstein, L. Lee, A. Pellicer, Y. Cheng, and R. Axel. 1977. Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell 11:223-232.
   PubMed Web of Science ®Google Scholar