13
Views
55
CrossRef citations to date
0
Altmetric
Cell Growth and Development

RelB, a New Rel Family Transcription Activator That Can Interact with p50-NF-κB

, , , , , & show all
Pages 674-684 | Received 23 Sep 1991, Accepted 11 Nov 1991, Published online: 01 Apr 2023

REFERENCES

  • Almendral, J. M., D. Sommer, H. Macdonald-Bravo, J. Burckhardt, J. Perera, and R. Bravo. 1988. Complexity of the early genetic response to growth factors in mouse fibroblasts. Mol. Cell. Biol. 8:2140–2148.
  • Atwater, J. A., R. Wisdom, and I. M. Verma. 1990. Regulated mRNA stability. Annu. Rev. Genet. 24:519–541.
  • Baeuerle, P. A., and D. Baltimore. 1988. Activation of DNA- binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell 53:211–217.
  • Baeuerle, P. A., and D. Baltimore. 1988. IκB: a specific inhibitor of the NF-κB transcription factor. Science 242:540–546.
  • Baeuerle, P. A., and D. Baltimore. 1989. A 65 kD subunit of active NF-κB is required for inhibition of NF-κB by IκB. Genes Dev. 3:1689–1698.
  • Ballard, D. W., W. H. Walker, S. Doerre, P. Sista, J. A. Molitor, E. P. Dixon, N. J. Peffer, M. Hannink, and W. C. Greene. 1990. The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function. Cell 63:803–814.
  • Bours, V., P. R. Burd, K. Brown, J. Villalobos, S. Park, R.-P. Ryseck, R. Bravo, K. Kelly, and U. Siebenlist. 1992. A novel mitogen-inducible gene product related to p50/p105-NF-κB participates in transactivation through a κB site. Mol. Cell. Biol. 12:685–695.
  • Bours, V., J. Villalobos, P. R. Burd, K. Kelly, and U. Siebenlist. 1990. Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs. Nature (London) 348:76–80.
  • Bravo, R. 1990. Growth factor inducible genes, p. 324–343. In A. Habenicht (ed.), Growth factors, differentiation factors, and cytokines. Springer Verlag KG, Berlin.
  • Brownell, E., N. Mittereder, and N. R. Rice. 1989. A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon. Oncogene 4:935–942.
  • Bull, P., T. Hunter, and I. M. Verma. 1989. Transcriptional induction of the murine c-rel gene with serum and phorbol-12- myristate-13-acetate in fibroblasts. Mol. Cell. Biol. 9:5239–5243.
  • Bull, P., K. L. Morley, M. F. Hoekstra, T. Hunter, and I. M. Verma. 1990. The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Mol. Cell. Biol. 10:5473–5485.
  • Capobianco, A. J., D. L. Simmons, and T. D. Gilmore. 1990. Cloning and expression of a chicken c-rel cDNA: unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts. Oncogene 5:257–265.
  • Cochran, B. H., A. C. Reffel, and C. D. Stiles. 1983. Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell 33:939–947.
  • Davis, N., S. Ghosh, D. L. Simmons, P. Tempst, H.-C. Liou, D. Baltimore, and H. R. Bose, Jr. 1991. Rel-associated pp40: an inhibitor of the Rel family of transcriptional factors. Science 253:1268–1271.
  • Ghosh, S., and D. Baltimore. 1990. Activation in vitro of NF-κB by phosphorylation of its inhibitor IκB. Nature (London) 344:678–682.
  • Ghosh, S., A. M. Gifford, L. R. Riviere, P. Tempst, G. P. Nolan, and D. Baltimore. 1990. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell 62:1019–1029.
  • Gilmore, T. D. 1990. NF-κB, KBF1, dorsal and related matters. Cell 62:841–843.
  • Gilmore, T. D., and H. M. Temin. 1988. v-rel oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells. J. Virol. 62:703–714.
  • Gorman, C., L. F. Moffat, and B. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Grumont, R. J., and S. Gerondakis. 1989. Structure of a mammalian c-rel protein deduced from the nucleotide sequence of murine cDNA clones. Oncogene Res. 4:1–8.
  • Haskill, S., A. A. Beg, S. M. Tompkins, J. S. Morris, A. D. Yurochko, A. Sampson-Johannes, K. Mondal, P. Ralph, and A. S. Baldwin, Jr. 1991. Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity. Cell 65:1281–1289.
  • Herschman, H. R. 1991. Primary response genes induced by growth factors and tumor promoters. Annu. Rev. Biochem. 60:281–319.
  • Ip, Y. T., R. Kraut, M. Levin, and C. A. Rushlow. 1991. The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in Drosophila. Cell 64:439–446.
  • Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact cells treated with alkali cations. J. Bacteriol. 153:163–168.
  • Johnston, M., and R. W. Davis. 1984. Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol. Cell. Biol. 4:1440–1448.
  • Kamens, J., P. Richardson, G. Mosialos, R. Brent, and T. Gilmore. 1990. Oncogenic transformation by v-Rel requires an amino-terminal activation domain. Mol. Cell. Biol. 10:2840–2847.
  • Kerr, L. D., J.-I. Inoue, N. Davis, I. Link, P. A. Baeuerle, H. R. Bose, Jr., and I. M. Verma. 1991. The Rel-associated pp40 protein prevents DNA binding of Rel and NF-κB: relationship with IκB and regulation by phosphorylation. Genes Dev. 5:1464–1476.
  • Kieran, M., V. Blank, F. Logeat, J. Vandekerckhove, F. Lottspeich, O. Le Bail, M. B. Urban, P. Kourilsky, P. A. Baeuerle, and A. Israel. 1990. The DNA binding subunit of NF-κB is identical to factor KB Fl and homologous to the rel oncogene product. Cell 62:1007–1018.
  • Kozak, M. 1989. The scanning model for translation: an update. J. Cell Biol. 108:229–241.
  • Landschulz, W. H., P. F. Johnson, and S. L. McKnight. 1988. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 240:1759–1764.
  • Lau, L. F., and D. Nathans. 1985. Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells. EMBO J. 4:3145–3151.
  • Lau, L. F., and D. Nathans. 1987. Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. Proc. Natl. Acad. Sci. USA 84:1182–1186.
  • Lau, L. F., and D. Nathans. 1991. Genes induced by serum growth factors, p. 165–201. In P. Cohen and J. G. Foulkes (ed.), The hormonal control regulation of gene transcription. Science Publishing, Inc., New York.
  • Lee, J., Y. Li, S. Doerre, P. Sista, D. W. Ballard, W. C. Greene, and B. R. Franza, Jr. 1991. A member of the set of κB binding proteins, HIVEN86A, is a product of the human c-rel protooncogene. Oncogene 6:665–667.
  • Lenardo, M. J., and D. Baltimore. 1989. NF-κB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58:227–229.
  • Lewin, B. 1991. Oncogenic conversion by regulatory changes in transcription factors. Cell 64:303–312.
  • Lim, M. Y., N. Davis, J. Zhang, and H. R. Bose. 1990. The v-rel oncogene product is complexed with cellular proteins including its proto-oncogene product and heat shock protein 70. Virology 175:149–160.
  • Lim, R. W., B. C. Varnum, and H. R. Herschman. 1987. Cloning of tetradecanoyl phorbol ester-induced 'primary response' sequences and their expression in density-arrested Swiss 3T3 cells and a TP A non-proliferative variant. Oncogene 1:263–270.
  • Luckow, B., and G. Schutz. 1987. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res. 15:5490.
  • Ma, J., and M. Ptashne. 1987. A new class of yeast transcriptional activators. Cell 51:113–119.
  • Ma, J., and M. Ptashne. 1987. Deletion analysis of GAL4 defines two transcriptional activation segments. Cell 48:847–853.
  • Malone, R. E., and M. F. Hoekstra. 1984. Relationship between a hyper-rec mutation (reml) and other recombination and repair genes in yeast. Genetics 107:33–48.
  • Martin-Zanca, D., R. Oskam, G. Mitra, T. Copeland, and M. Barbacid. 1989. Molecular and biochemical characterization of the human trk proto-oncogene. Mol. Cell. Biol. 9:24–33.
  • Meyer, R., E. N. Hatada, H.-P. Hohmann, M. Haiker, C. Bartsch, U. Rothlisberger, H.-W. Lahm, E. J. Schaleger, A. P. G. M. van Loon, and C. Scheidereit. 1991. Cloning of the DNA-binding subunit of human nuclear factor κB: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor a. Proc. Natl. Acad. Sci. USA 88:966–970.
  • Morrison, L. E., N. Kabrun, S. Mudri, M. J. Hayman, and P. J. Enrietto. 1989. Viral rel and cellular rel associate with cellular proteins in transformed and normal cells. Oncogene 4:677–683.
  • Nabel, G. and D. Baltimore. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature (London) 326:711–713.
  • Nolan, G. P., S. Ghosh, H.-C. Lion, P. Tempst, and D. Baltimore. 1991. DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide. Cell 64:961–969.
  • Richardson, P. M., and T. D. Gilmore. 1991. v-rel is an inactive member of the Rel family of transcriptional activating proteins. J. Virol. 65:3122–3130.
  • Ruben, S. M., P. J. Dillon, R. Schreck, T. Henkel, C.-H. Chen, M. Maher, P. A. Baeuerle, and C. A. Rosen. 1991. Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-κB. Science 251:1490–1493.
  • Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463–5467.
  • Schmid, R. M., N. D. Perkins, C. S. Duckett, P. C. Andrews, and G. J. Nabel. 1991. Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65. Nature (London) 352:733–736.
  • Simek, S., and N. R. Rice. 1988. p59v-rel, the transforming protein of retjculeondotheliosis virus, is complexed with at least four other proteins in transformed chicken lymphoid cells. J. Virol. 62:4730–4736.
  • Stephens, R. M., N. R. Rice, R. R. Hiebsch, H. R. Bose, and R. V. Gilden. 1983. Nucleotide sequence of v-rel: the oncogene of the reticuloendotheliosis virus. Proc. Natl. Acad. Sci. USA 80:6229–6232.
  • Steward, R. 1987. Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel. Science 238:692–694.
  • Strebel, K., E. Beck, K. Strohmaier, and H. Schaller. 1986. Characterization of foot-and-mouth disease virus gene products with antisera against bacterially synthesized fusion proteins. J. Virol. 57:983–991.
  • Theilen, G., R. Zeigel, and M. Tweihaus. 1966. Biological studies with RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quails. J. Natl. Cancer Inst. 37:747–749.
  • Thisse, C., F. Perrin-Schmitt, C. Stoetzel, and B. Thisse. 1991. Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene product. Cell 65:1191–1201.
  • Urban, M. B., and P. A. Baeuerle. 1991. The role of the p50 and p65 subunits of NF-κB in the recognition of cognate sequences. New Biol. 3:279–288.
  • Urban, M. B., R. Schreck, and P. A. Baeuerle. 1991. NF-κB contacts DNA by heterodimer of the p50 and p65 subunit. EMBO J. 10:1817–1825.
  • Wilhelmsen, K. C., K. Eggleton, and H. M. Temin. 1984. Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the protooncogene c-rel. J. Virol. 52:172–182.
  • Yocum, R. R., S. Hanley, R. West, and M. Ptashne. 1984. Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol. Cell. Biol. 4:1985–1998.
  • Zabel, U., and P. A. Baeuerle. 1990. Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA. Cell 61:255–265.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.