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Cell Growth and Development

Growth-Regulated Expression of rhoG, a New Member of the ras Homolog Gene Family

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Pages 3138-3148 | Received 08 Oct 1991, Accepted 17 Apr 1992, Published online: 01 Apr 2023

References

  • Abo, Α., Ε. Pick, A. Hall, Ν. Totty, C. G. Teahan, and A. W. Segal. 1991. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1. Nature (London) 353:668–670.
  • Almendral, J. M., D. Sommer, J. Perera, J. Burckardt, H. MacDonald-Bravo, and R. Bravo. 1988. Complexity of early genetic response to growth factors in mouse fibroblasts. Mol. Cell. Biol. 8:2140–2148.
  • Avraham, H., and R. A. Weinberg. 1989. Characterization and expression of the human rhoH12 gene product. Mol. Cell. Biol. 9:2058–2066.
  • Bacon, R. Α., A. Salminen, H. Ruhohala, P. Novick, and S. Ferro-Novick. 1989. The GTP-binding protein YPT1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J. Cell Biol. 109:1015–1022.
  • Barbacid, M. 1987. ras genes. Annu. Rev. Biochem. 56:779–828.
  • Belyavsky, Α., Τ. Vinogradova, and K. Rajewsky. 1989. PCR-based cDNA library construction: general cDNA libraries at the level of a few cells. Nucleic Acids Res. 17:2919–2932.
  • Berridge, M. J., and R. F. Irvine. 1984. Inositol trisphosphate, a novel second messenger in signal transduction. Nature (London) 312:315–321.
  • Bird, A. P. 1987. CpG-rich islands and the function of hemi-methylation. Nature (London) 321:209–213.
  • Bos, J. L. 1988. The ras family and human carcinogenesis. Mutat. Res. 195:255–262.
  • Bourne, H. R., D. A. Sanders, and F. McCormick. 1990. The GTPase superfamily: a conserved switch for diverse cell functions. Nature (London) 348:125–132.
  • Bourne, H. R., D. A. Sanders, and F. McCormick. 1991. The GTPase superfamily: conserved structure and molecular mechanism. Nature (London) 349:117–123.
  • Brawerman, G. 1989. mRNA decay: finding the right targets. Cell 57:9–10.
  • Caput, D. Personal communication.
  • Castagna, M., Y. Takai, K. Kaibuchi, K. Sano, U. Kikkawa, and Y. Nishizuka. 1982. Direct activation of calcium activated phospholipid dependent protein kinase by tumor promoting phorbolesters. J. Biol. Chem. 257:7847.
  • Chardin, P., P. Boquet, P. Madaule, M. R. Popoff, E. J. Rubin, and D. M. Gill. 1989. The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells. EMBO J. 8:1087–1092.
  • Chardin, P., P. Madaule, and A. Tavitian. 1988. Coding sequences of human rho cDNAs clone 6 and clone 9. Nucleic Acids Res. 16:2717.
  • Chardin, P., and A. Tavitian. 1986. The ral gene: a new ras-related gene isolated by the use of a synthetic probe. EMBO J. 5:2203–2208.
  • Ciccarelli, C., L. Philipson, and V. Sorrentino. 1989. Regulation of expression of growth arrest-specific genes in mouse fibroblasts. Mol. Cell. Biol. 10:1525–1529.
  • Cochran, B. H., A. C. Reffel, and C. D. Stiles. 1983. Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell 33:939–947.
  • Dessen, P., C. Fondrat, C. Valencien, and C. Mugnier. 1990. BISANCE: a French service for access to biomolecular sequence databases. Cabios 6:355–356.
  • Didsbury, J., R. F. Weber, G. M. Bokoch, T. Evans, and R. Synderman. 1989. Rac, a novel Ras-related family of proteins that are botulinum toxin substrates. J. Biol. Chem. 264:16378–16382.
  • Dieckmann, D., S. Brill, M. D. Garrett, N. Totty, J. Hsuan, C. Monfries, C. Hall, L. Lim, and A. Hall. 1991. Bcr encodes a GTPase-activating protein for p21rac. Nature (London) 351:400–402.
  • Drivas, G. T., A. Shih, E. Coutavas, M. G. Rush, and P. D’Eustachio. 1990. Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line. Mol. Cell. Biol. 10:1793–1798.
  • Ellis, R. W., D. De Feo, T. Y. Shih, M. A. Gonda, H. A. Young, N. Tsuchida, D. Lowy, and E. Scolnick. 1981. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature (London) 292:506–511.
  • Evans, T., M. L. Brown, E. D. Fraser, and J. K. Northup. 1986. Purification of the major GTP-binding proteins from human placental membranes. J. Biol. Chem. 261:7052–7059.
  • Felsenstein, J. 1981. Evolutionary trees from DNA sequences: a maximum likelihood approach. J. Mol. Evol. 17:368–376.
  • Fort, P., J. Rech, A. Vie, M. Piechaczyk, A. Bonnieu, P. Jeanteur, and J.-M. Blanchard. 1987. Regulation of c-fos gene expression in hamster fibroblasts: initiation and elongation of transcription and mRNA degradation. Nucleic Acids Res. 15:5657–5667.
  • Frazier, W. A. 1991. Thromspondins. Curr. Opin. Cell Biol. 3:792–799.
  • Greenberg, M. E., and E. B. Ziff. 1984. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (London) 311:433–438.
  • Hart, M. J., A. Eva, T. Evans, S. A. Aaronson, and R. A. Cerione. 1991. Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. Nature (London) 354:311–314.
  • Hein, J. L. 1989. A unified approach to alignments and phytogenies. Methods Enzymol. 183:626–645.
  • Herschmann, H. R. 1991. Primary response genes induced by growth factors and tumor promoters. Annu. Rev. Biochem. 60:281–319.
  • Hirschhorn, R. R., P. Aller, Z. A. Yuan, C. W. Gibson, and R. Baserga. 1984. Cell-cycle-specific cDNAs from mammalian cells temperature sensitive for growth. Proc. Natl. Acad. Sci. USA 81:6004–6008.
  • Jähner, D., and T. Hunter. 1991. The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts. Mol. Cell. Biol. 11:3682–3690.
  • Johnson, D. I., and J. R. Pringle. 1990. Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity. J. Cell Biol. 111:143–152.
  • Kikuchi, Α., Τ. Yamashita, Μ. Kawata, Κ. Yamamoto, Κ. Ikeda, Τ. Taminoto, and Y. Takai. 1988. Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes. J. Biol. Chem. 263:2897–2904.
  • Lau, L. F., and D. Nathans. 1985. Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells. EMBO J. 4:3145–3151.
  • Lau, L. F., and D. Nathans. 1987. Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. Proc. Natl. Acad. Sci. USA 84:1182–1186.
  • Leonard, D. G., A. B. Ziff, and L. A. Greene. 1987. Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Mol. Cell. Biol. 7:3156–3167.
  • Lowe, D. G., D. J. Capon, E. Delwart, A. Y. Sakaguchi, S. L. Naylor, and D. V. Goeddel. 1987. Structure of the human and murine R-ras genes, novel genes closely related to ras protooncogenes. Cell 48:137–146.
  • Lu, K., R. A. Levine, and J. Campisi. 1989. c-ras-Ha gene expression is regulated by insulin or insulinlike growth factor and by epidermal growth factor in murine fibroblasts. Mol. Cell. Biol. 9:3411–3417.
  • Madaule, P., and R. Axel. 1985. A novel ras-related gene family. Cell 41:31–40.
  • Madaule, P., R. Axel, and A. Myers. 1987. Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 84:779–783.
  • Magnaldo, I., G. L’Allemain, J. C. Chambard, M. Moenner, D. Barritault, and J. Pouysségur. 1986. The mitogenic signalling pathway of fibroblast growth factor is not mediated through polyphosphoinositide hydrolysis and protein kinase C activation in hamster fibroblasts. J. Biol. Chem. 261:16916–16922.
  • Magnaldo, I., J. Pouyssegur, and S. Paris. 1988. Thrombin exerts a dual effect on stimulated adenylate cyclase in hamster fibroblasts: an induction via a GTP-binding protein and a potentiation via activation of protein kinase C. Biochem. J. 253:711–719.
  • Magnaldo, I., J. Pouyssegur, and S. Paris. 1989. Cyclic AMP inhibits mitogen-induced DNA synthesis in hamster fibroblasts, regardless of the signalling pathway involved. FEBS Lett. 245:65–69.
  • Majack, R. Α., J. Milbrandt, and V. M. Dixit. 1987. Induction of thrombospondin messenger RNA levels occurs as an immediate primary response to platelet-derived growth factor. J. Biol. Chem. 262:8821–8825.
  • Munemitsu, S., M. A. Innis, R. Clark, F. McCormick, A. Ullrich, and P. Polakis. 1990. Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42. Mol. Cell. Biol. 10:5977–5982.
  • Nikaido, T., D. W. Bradley, and A. Pardee. 1991. Molecular cloning of transcripts that accumulate during the late G1 phase in cultured mouse cells. Exp. Cell Res. 192:102–109.
  • Olofsson, B., P. Chardin, N. Touchot, A. Zarahoui, and A. Tavitian. 1988. Expression of the ras-related ralA, rho12 and rab genes in adult mouse tissues. Oncogene 3:231–234.
  • Paterson, H., A. J. Self, M. D. Garrett, I. Just, K. Aktories, and A. Hall. 1990. Microinjection of recombinant p21rho induces rapid changes in cell morphology. J. Cell Biol. 111:1001–1007.
  • Piechaczyk, M., J. M. Blanchard, L. Marty, C. Dani, F. Panabieres, S. El Sabrouty, P. Fort, and P. Jeanteur. 1984. Glycer-aldehyde-3-phosphate dehydrogenase gene expression is regulated at the post-transcriptional level in rat tissues. Nucleic Acid Res. 12:6951–6963.
  • Pizon, V., P. Chardin, I. Lerosey, B. Olofsson, and A. Tavitian. 1988. Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to Ras in the effector region. Oncogene 3:201–204.
  • Polakis, P. G., R. F. Weber, B. Nevins, J. R. Didsbury, T. Evans, and R. Snyderman. 1989. Identification of the ral and rac1 gene products, low molecular GTP-binding proteins from human platelets. J. Biol. Chem. 28:16383–16389.
  • Pouyssegur, J. 1990. G-proteins in growth factors action, p. 555–570. In L. Birnbaumer and R. Iyengar (ed.), G-proteins. Academic Press, Inc., New York.
  • Pouyssegur, J., C. Kahan, and K. Seuwen. 1990. Transmembrane signalling pathways initiating cell growth. Role of G-protein coupled receptors, p. 80–100. In S. Weber (ed.), Growth factors: from genes to clinical application. Raven Press, New York.
  • Reibel, L., O. Dorseuil, R. Stancou, J. Bertoglio, and G. Gacon. 1991. A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during Τ cell activation. Biochem. Biophys. Res. Commun. 175:451–458.
  • Rüther, U., E. F. Wagner, and R. Muller. 1985. Analysis of the differentiation-promoting potential of inducible c-fos genes introduced into embryonal carcinoma cells. EMBO J. 4:1775–1781.
  • Santos, E., and R. Nebreda. 1989. Structural and functional properties of Ras proteins. FASEB J. 3:2151–2163.
  • Schneider, C., R. M. King, and L. Philipson. 1988. Genes specifically expressed at growth arrest of mammalian cells. Cell 54:787–793.
  • Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659–667.
  • Shinjo, K., J. G. Koland, M. J. Hart, V. Narasimhan, D. I. Johnson, T. Evans, and R. A. Cerione. 1990. Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division cycle protein CDC42. Proc. Natl. Acad. Sci. USA 87:9853–9857.
  • Touchot, N., P. Chardin, and A. Tavitian. 1987. Four additional members of the ras gene superfamily isolated by oligonucleotide strategy: molecular cloning or YPT-related cDNAs from a rat brain library. Proc. Natl. Acad. Sci. USA 84:8210–8214.
  • Valencia, Α., Ρ. Chardin, A. Wittinghofer, and C. Sander. 1991. The Ras family: evolutionary tree and role of conserved amino acids. Biochemistry 19:4637–4648.
  • Van der Slugs, P., M. Hull, A. Zarahoui, A. Tavitian, B. Goud, and I. Mellman. 1991. The small GTP-binding protein Rab4 is associated with early endosomes. Proc. Natl. Acad. Sci. USA 88:6313–6317.
  • Van Obberghem-Schilling, E., J. C. Chambard, S. Paris, G. L’Allemain, and J. Pouyssegur. 1983. α-Thrombin-induced early mitogenic signalling events and G0 to S-phase transition of fibroblasts require continuous external stimulation. EMBO J. 4:2927–2932.
  • Vincent, S. Unpublished results.
  • Vincent, S., and P. Fort. 1990. Nucleotide sequence of hamster glyceraldehyde-3-phosphate dehydrogenase mRNA. Nucleic Acids Res. 10:3054.
  • Wilson, T., and R. Treisman. 1988. Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences. Nature (London) 336:396–399.
  • Yarden, Y., and A. Ullrich. 1988. Growth factor receptor tyrosine kinases. Annu. Rev. Biochem. 57:453–478.
  • Yeramian, P., P. Chardin, P. Madaule, and A. Tavitian. 1987. Nucleotide sequence of human rho cDNA clone 12. Nucleic Acids Res. 15:189.

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