Transcriptional Regulation of the Apolipoprotein B100 Gene: Purification and Characterization of trans -Acting Factor BRF-2

References

• Borgmeyer, U., J. Nowock, and A. E. Sippel. 1984. The TGGCA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double stranded linear DNA. Nucleic Acids Res. 12:4295–4311.
   PubMedGoogle Scholar
• Brooks, A. R., B. D. Blackhart, K. Haubold, and B. Levy-Wilson. 1991. Characterization of tissue-specific enhancer elements in the second intron of the human apolipoprotein Β gene. J. Biol. Chem. 266:7848–7859.
   PubMedGoogle Scholar
• Carlsson, P., and G. Bjursell. 1989. Negative and positive promoter elements contribute to tissue specificity of apolipoprotein Β expression. Gene 77:113–121.
   PubMedGoogle Scholar
• Carlsson, P., P. Eriksson, and G. Bjursell. 1990. Two nuclear proteins bind to the major positive element of the apolipoprotein Β gene promoter. Gene 94:295–301.
   PubMedGoogle Scholar
• Collins, D. R., T. J. Knot, R. J. Pease, L. M. Powell, S. C. Wallis, S. Robertson, C. R. Pullinger, R. W. Milne, Y. L. Marcel, S. E. Humphries, P. J. Talmud, J. K. Lloyd, Ν. Ε. Miller, D. Muller, and J. Scot. 1988. Truncated variants of apolipoprotein Β cause hypobetalipoproteinemia. Nucleic Acids Res. 16:8361–8375.
   PubMedGoogle Scholar
• Costa, R. R., D. R. Grayson, and J. E. Darnell, Jr. 1989. Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and α1-antitrypsin genes. Mol. Cell. Biol. 9:1415–1425.
   PubMed Web of Science ®Google Scholar
• Courtois, G., J. G. Morgan, L. A. Campbell, G. Fourel, and G. R. Crabtree. 1987. Interaction of a liver-specific nuclear factor with fibrinogen and alpha 1-antitrypsin promoters. Science 238:688–692.
   PubMed Web of Science ®Google Scholar
• Das, Η. Κ., Τ. Leff, and J. L. Breslow. 1988. Cell type-specific expression of the human apoB gene is controlled by two cis-acting regulatory regions. J. Biol. Chem. 263:11452–11458.
   PubMedGoogle Scholar
• Dignam, J. D., R. M. Lebowitz, and R. G. Roeder. 1983. Accurate transcription by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
   PubMed Web of Science ®Google Scholar
• Frain, M., G. Swart, P. Monaci, A. Nicosia, S. Stampfli, R. Frank, and R. Cortese. 1989. The liver-specific transcription factor LF-B1 contains a diverged homeobox DNA binding domain. Cell 59:145–157.
   PubMed Web of Science ®Google Scholar
• Goldstein, J. L., and M. S. Brown. 1977. The low density lipoprotein pathway and its relation to atherosclerosis. Annu. Rev. Biochem. 46:897–930.
   PubMed Web of Science ®Google Scholar
• Goldstein, J. L., and M. S. Brown. 1982. Familial hypercholesterolemia, p. 672–712. In J. B. Stanbury, J. B. Wyngaarden, D. S. Fredrickson, J. L. Goldstein, and M. S. Brown (ed.), The metabolic basis of inherited disease, 5th ed. McGraw-Hill Book Co., New York.
   Google Scholar
• Gorsky, C. Μ., Μ. Carneiro, and U. Schibler. 1986. Tissue-specific in vitro transcription from the mouse albumin promoter. Cell 47:767–776.
   PubMedGoogle Scholar
• Grayson, D. R., R. H. Costa, K. G. Xanthopoulos, and J. E. Darnell, Jr. 1988. One factor recognizes the liver-specific enhancers in alpha 1-antitrypsin and transthyretin genes. Science 239:786–788.
   PubMedGoogle Scholar
• Havel, R. J., and J. P. Kane. 1989. Disorders of the biogenesis and secretion of lipoproteins containing the Β apolipoproteins, p. 1139–1164. In J. B. Stanbury, J. B. Wyngaarden, D. S. Frederickson, J. L. Goldstein, and M. S. Brown (ed.), The metabolic basis of inherited disease, 6th ed. McGraw-Hill Book Co., New York.
   Google Scholar
• Johnson, P. F., W. H. Landschulz, B. J. Graves, and S. L. McKnight. 1987. Identification of a rat liver nuclear protein that binds to the core element of three animal viruses. Genes Dev. 1:133–146.
   PubMed Web of Science ®Google Scholar
• Kadonaga, J. T., and R. Tjian. 1986. Affinity purification of sequence-specific DNA binding proteins. Proc. Natl. Acad. Sci. USA 83:5889–5893.
   PubMed Web of Science ®Google Scholar
• Kannel, W. B., W. P. Castelli, and T. Gorton. 1979. Cholesterol in the prediction of atherosclerotic disease. Ann. Intern. Med. 90:85–91.
   PubMed Web of Science ®Google Scholar
• Kardassis, D., M. Hadzopoulou-Cladaras, D. P. Ramji, R. Cortese, V. I. Zannis, and C. Cladaras. 1990. Characterization of the promoter elements required for hepatic and intestinal transcription of the human apoB gene: definition of the DNA-binding site of a tissue-specific transcriptional factor. Mol. Cell. Biol. 10:2653–2659.
   PubMedGoogle Scholar
• Kardassis, D., V. I. Zannis, and C. Cladaras. 1990. Purification and characterization of the nuclear factor BA1: a transcriptional activator of the human apoB gene. J. Biol. Chem. 265:21733–21740.
   PubMedGoogle Scholar
• Kuwabara, M. D., and D. S. Sigman. 1987. Footprinting DNA-protein complexes in situ following gel retardation assays using 1,10 phenanthroline-copper ion: Escherichia coli RNA polymerase-lac promoter complexes. Biochemistry 26:7234–7238.
   PubMedGoogle Scholar
• Ladias, J. Α. Α., and S. K. Karathanasis. 1991. Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily. Science 251:561–565.
   PubMed Web of Science ®Google Scholar
• Lai, E., V. R. Prezioso, E. Smith, O. Litvin, R. H. Costa, and J. E. Darnell, Jr. 1990. HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev. 4:1427–1436.
   PubMed Web of Science ®Google Scholar
• Lai, E., V. R. Prezioso, W. Tao, W. S. Chen, and J. E. Darnell, Jr. 1991. Hepatocyte nuclear factor 3 belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev. 5:416–427.
   PubMed Web of Science ®Google Scholar
• Lee, W., P. Mitchell, and R. Tjian. 1987. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49:741–752.
   PubMed Web of Science ®Google Scholar
• Li, Y., R.-F. Shen, S. Y. Tsai, and S. L. C. Woo. 1988. Multiple hepatic trans-acting factors are required for in vitro transcription of the human alpha-1-antitrypsin gene. Mol. Cell. Biol. 8:4362–4369.
   PubMedGoogle Scholar
• Lichtsteiner, S., J. Wuarin, and U. Schibler. 1987. The interplay of DNA-binding proteins on the promoter of the mouse albumin gene. Cell 51:963–973.
   PubMed Web of Science ®Google Scholar
• Maxam, A. M., and W. Gilbert. 1980. Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65:499–560.
   PubMedGoogle Scholar
• Mendel, D. B., and G. R. Crabtree. 1991. HNF-1, a member of a novel class of dimerizing homeodomain proteins. J. Biol. Chem. 266:677–680.
   PubMed Web of Science ®Google Scholar
• Metzger, S., T. Leff, and J. L. Breslow. 1990. Nuclear factors AF-1 and C/EBP bind to the human apoB gene promoter and modulate its transcriptional activity in hepatic cells. J. Biol. Chem. 265:9978–9983.
   PubMedGoogle Scholar
• Paonessa, G., F. Gounari, R. Frank, and R. Cortese. 1988. Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA. EMBO J. 7:3115–3123.
   PubMedGoogle Scholar
• Raymondjean, M., S. Cereghini, and M. Yaniv. 1988. Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells. Proc. Natl. Acad. Sci. USA 85:757–761.
   PubMedGoogle Scholar
• Roy, N. K., and Η. Κ. Das. Unpublished data.
   Google Scholar
• Saul, Y., R. Ben-Levy, and T. De-Medina. 1986. High affinity binding site for nuclear factor I next to hepatitis Β virus S gene promoter. EMBO J. 5:1967–1971.
   PubMedGoogle Scholar
• Siervogel, R. M., J. A. Morrison, K. Kelly, M. Meliles, P. Gartside, and C. Glueck. 1980. Familial hyper-alpha-lipoproteinemia in 26 kindreds. J. Clin. Genet. 17:13.
   PubMedGoogle Scholar
• Sladek, F. M., W. Zhong, E. Lai, and J. E. Darnell, Jr. 1990. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev. 4:2353–2365.
   PubMed Web of Science ®Google Scholar
• Young, S. G., S. J. Bertices, L. K. Curtiss, B. W. Dubois, and J. L. Witztum. 1987. Genetic analysis of a kindred with familial hypobetalipoproteinemia, evidence for two separate gene defects: one associated with an abnormal apolipoprotein Β species, apolipoprotein B-37; and a second associated with low plasma concentrations of apolipoprotein B-100. J. Clin. Invest. 79:1842–1859.
   PubMedGoogle Scholar
• Young, S. G., S. J. Bertices, L. K. Curtiss, and J. L. Witzum. 1987. Characterization of an abnormal species of apolipoprotein B, apolipoprotein B-37, associated with familial hypobetalipoproteinemia. J. Clin. Invest. 79:1831–1841.
   PubMedGoogle Scholar
• Young, S. G., S. T. Northey, and B. J. McCarthy. 1988. Low plasma cholesterol levels caused by a short deletion of the apolipoprotein Β gene. Science 241:591–593.
   PubMedGoogle Scholar